Dermatology practical & conceptual最新文献

{"title":"Dermoscopic Features of Eccrine Poromas in Diverse Skin Phototypes: A Retrospective Study of 26 Cases.","authors":"Bengu Nisa Akay, Handan Merve Erol Mart, Aylin Okcu Heper","doi":"10.5826/dpc.1502a5071","DOIUrl":"10.5826/dpc.1502a5071","url":null,"abstract":"<p><strong>Introduction: </strong>Eccrine poroma (EP) is a benign adnexal tumor. Establishing a definitive diagnosis based on clinical and dermoscopic findings can be challenging.</p><p><strong>Objectives: </strong>The aim of this study was to perform a comprehensive analysis of the dermoscopic features of pigmented, hypopigmented, and nonpigmented variants of EP and to compare these dermoscopic features in patients with dark and light Fitzpatrick skin phototypes.</p><p><strong>Methods: </strong>A total of 26 cases of histopathologically confirmed EP were included. Each case was categorized as pigmented, hypopigmented, or nonpigmented based on the melanin content within the lesion. Patients were classified according to their Fitzpatrick skin phototypes. Dermoscopic images were subjected to revised pattern analysis, and the results were compared with the existing literature.</p><p><strong>Results: </strong>Regarding Fitzpatrick skin phototype, four (15.4%), 11 (42.3%), six (23.1%), and five (19.2%) patients had Fitzpatrick skin phototypes II, III, IV, and V, respectively. Of the cases, 17 (65.4%) were classified as nonpigmented, three (11.5%) as hypopigmented, and six (23.1%) as pigmented EP. All pigmented EP cases occurred in patients with dark skin and were located on non-acral sites. Polymorphic vascular pattern, branched vessels with rounded endings, linear-irregular vessels, interlacing white areas around vessels, and collarettes were more frequently observed in patients with light skin. In contrast, clod vessels, coiled vessels, white lines, ulceration, fiber sign, scales, and structureless areas were more common in patients with dark skin.</p><p><strong>Conclusions: </strong>This study underscores the significant dermoscopic diversity observed in EP, revealing distinct patterns based on pigmentation and Fitzpatrick skin phototypes.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatal Disseminated Mucormycosis by Cunninghamella in Newly Diagnosed Acute Myeloid Leukemia: Case Report and Diagnostic Challenges.","authors":"Sebastián González-Valdés, Magdalena Vial, Renate Steffen, Mauricio Lechuga","doi":"10.5826/dpc.1502a5016","DOIUrl":"10.5826/dpc.1502a5016","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sun Protection Knowledge and Practices in Fifth-year Medical Students: Impact of Gender, Sunburn Experience and Sunscreen Use.","authors":"Funda Tamer, Emre Guven, Esra Adisen","doi":"10.5826/dpc.1502a4996","DOIUrl":"10.5826/dpc.1502a4996","url":null,"abstract":"<p><strong>Introduction: </strong>Ultraviolet exposure is the most important modifiable risk factor for developing skin cancer.</p><p><strong>Objectives: </strong>We evaluated the knowledge and behaviors of medical students regarding sun protection.</p><p><strong>Methods: </strong>Between October 2023 and May 2024, fifth-year medical students filled a questionnaire on sun protection.</p><p><strong>Results: </strong>This study included 255 students: 134 males and 121 females. Among them, 100 (39.2%) students stated that they always used sunscreen, 43.1% used sunscreen on sunny days and in the winter, whereas 42% applied it only to the face. Of the 135 students who knew the two-finger technique, 99 stated that they had learned this information from social media, and 218 (85.5%) took at least one other sun protection measure. In females, wearing sunscreen (P<0.001), reapplying it (P=0.003), using it in winter (P<0.001), knowing the two-finger technique (P<0.001), and taking other sun protection measures (P=0.020) were more frequent and duration of sunscreen use was longer (P<0.001) compared to males. Sunburn was more common in males and in those who stated that they did not go out during peak sun time (P=0.013, P=0.017, respectively). Statements on sun protection were similar in both sexes. For instance, 95.9% of females and 96.3% of males revealed that sun protection prevents skin cancer.</p><p><strong>Conclusion: </strong>Although females used sunscreen and applied other sun protection methods more frequently than did males, appropriate sunscreen use was inadequate among all students. Updating the curriculum and providing educational social media sites where reliable information can be obtained may improve medical students' sun protection habits.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopy of de novo Syringocystadenoma Papilliferum in Dark and Fair Skin.","authors":"Noemi Plozner, Maitha Abdulla Aljuwaied, Esmaeel AlSayed Mohamed Almarzooqi, Mohammed Ahmed, Giuseppe Stinco, Enzo Errichetti","doi":"10.5826/dpc.1502a5393","DOIUrl":"10.5826/dpc.1502a5393","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective Sequential and Rotational Therapy in a Patient With Xeroderma Pigmentosum.","authors":"Jimena Carrero Martín, Álvaro Núñez Domínguez, Marta López Pando, Raquel Santos-Juanes Galache, Cristina Galache Osuna, Jorge Santos-Juanes Jiménez","doi":"10.5826/dpc.1502a5168","DOIUrl":"10.5826/dpc.1502a5168","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal Implications of Psoriasis: Urinary Podocyte Markers and Disease Progression.","authors":"Sule Gencoglu, Meltem Yardim, Ramazan Fazil Akkoc","doi":"10.5826/dpc.1502a4910","DOIUrl":"10.5826/dpc.1502a4910","url":null,"abstract":"<p><strong>Introduction: </strong>Psoriasis may lead to glomerular inflammatory damage and disruption of the podocyte barrier, allowing podocyte degradation products to leak into the urine.</p><p><strong>Objectives: </strong>We aimed to analyze the concentrations of podocyte surface glycoprotein podocalyxin (PDX) and podocyte slit protein nephrin in spot urine samples from patients with mild, moderate, or severe psoriasis vulgaris.</p><p><strong>Methods: </strong>A total of 78 participants, including 58 patients diagnosed with mild, moderate, or severe psoriasis vulgaris and 20 healthy controls, were included in the study. Psoriasis was diagnosed based on the typical morphological characteristics of the lesions. Morning urine samples were used to evaluate urine PDX and nephrin levels. Albuminuria was evaluated by calculating the urine albumin-to-creatinine ratio (uACR).</p><p><strong>Results: </strong>Urinary PDX and nephrin levels were significantly higher in the psoriasis group than in the control group. Urinary PDX and nephrin levels in the mild and moderate psoriasis groups were similar but higher than those in the control group and significantly higher in the severe psoriasis group than in the mild and moderate psoriasis groups. The microalbuminuria rates were similar between the psoriasis and control groups. A significant positive correlation was observed between urine PDX, nephrin, uACR, and SBP. After adjusting for age, BMI, and sex, urine PDX and nephrin levels were found to be independent risk factors for microalbuminuria.</p><p><strong>Conclusion: </strong>This study showed that podocyte damage in patients with psoriasis begins in the early stages of the disease and significantly increases in the severe stage of the disease.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Skin Cancer Prevention and Awareness in the Italian Population: Insights from the \"Save Your Skin\" Screening Campaign.","authors":"Paola Savoia, Laura Cristina Gironi, Chiara Airoldi, Francesca Zottarelli, Mauro Alaibac, Marco Ardigò, Giuseppe Argenziano, Stefano Astorino, Francesco Bellinato, Luca Bianchi, Maurizio Congedo, Claudia Costa, Alessandro Di Stefani, Maria Concetta Fargnoli, Caterina Foti, Pasquale Frascione, Giampiero Girolomoni, Vieri Grandi, Fabrizio Guarneri, Katharina Hansel, Francesco Lacarruba, Serena Lembo, Angelo Valerio Marzano, Giuseppe Micali, Steven Paul Nisticò, Annamaria Offidani, Ketty Peris, Bianca Maria Piraccini, Pietro Quaglino, Marco Romanelli, Franco Rongioletti, Pietro Rubegni, Camilla Salvini, Massimiliano Scalvenzi, Paolo Sena, Marco Spadafora, Carlo Francesco Tomasini, Marina Venturini, Elisa Zavattaro","doi":"10.5826/dpc.1502a5350","DOIUrl":"10.5826/dpc.1502a5350","url":null,"abstract":"<p><strong>Introduction: </strong>Skin cancer prevention campaigns aim to reduce modifiable risk factors, yet high-risk groups often maintain inadequate protection practices.</p><p><strong>Objectives: </strong>This study analyzed data from Italy's 2023 \"Save Your Skin\" campaign, which provided free skin checks nationwide.</p><p><strong>Methods: </strong>Data from 1,773 participants across 29 centers in 13 regions were collected to assess sun exposure, photoprotection habits, and skin cancer awareness, identifying gaps in prevention efforts.</p><p><strong>Results: </strong>Most participants were female (70.16%), with a median age of 36, and 96.61% were born in Italy. While 71.24% joined for prevention reasons, others participated due to changes in a nevus (12.35%) or personal (2.31%) or family (7.33%) history of skin cancer. Self-assessments of nevi often did not align with dermatologists' evaluations, but family and personal history reporting was more accurate. Participants showed confusion about nevi and melanoma: only 52.7% correctly identified nevi as benign, while 67.2% recognized melanoma as malignant. On average, participants answered 1.57 out of three knowledge questions correctly, with those having a family or personal history of skin cancer performing better. High-risk sun exposure behaviors were identified in 37.78% of participants. Older adults used sunscreen less frequently but relied more on hats and shade, while younger individuals reported less sun exposure at work. Notably, participants with actinic damage demonstrated lower awareness and provided fewer correct answers on photoprotection.</p><p><strong>Conclusions: </strong>These findings underscore the need for targeted public health strategies to improve education on skin cancer prevention, particularly among high-risk and older populations.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scabies Management Outcomes: Identification of Risk Factors for Treatment Success or Failure.","authors":"Vanessa Azzolina, Franziska Schauer, Julia Felicitas Pilz, Alexander Zink, Kilian Eyerich, Anna Caroline Pilz","doi":"10.5826/dpc.1502a5077","DOIUrl":"10.5826/dpc.1502a5077","url":null,"abstract":"<p><strong>Introduction: </strong>Scabies is a parasitic infectious skin disease classified as a neglected tropical disease by the World Health Organization in 2017. Currently, it is becoming a major challenge in high-income countries, with rapidly rising incidence and increasing reports about treatment failure.</p><p><strong>Objectives: </strong>Factors that are associated with treatment failure or success were evaluated.</p><p><strong>Methods: </strong>This non-interventional prospective observational study was conducted as a questionnaire survey at the Department of Dermatology and Venereology of the University of Freiburg from January to November 2023. Patients that still suffered from scabies 2-6 weeks after medical treatment were classified as \"failure\"; those who were free of scabies belonged to the success group.</p><p><strong>Results: </strong>Of 102 participants, with a mean age of 34.4 ± 17.3 years (male: 60.4%), 77 (75.5%) were assigned to the success and 25 (24.5%) to the failure group. A larger proportion of the latter was clinically more severely affected, applied permethrin monotherapy, did not undertake special decontamination measures, but used alcohol as a disinfectant. Treatment success was associated with an additional systemic treatment, a repeated intake of ivermectin, and intensified decontamination measures such as storage of clothes in plastic bags for four days or vacuum cleaning of car seats.</p><p><strong>Conclusions: </strong>Our findings indicate that a consistent second-dose administration of ivermectin and refraining from permethrin monotherapy may be advisable.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Frequency of Microsatellite Metastases, Satellite Metastases, and Residual Tumor in Thin Melanomas: A Retrospective Cohort Study.","authors":"Ebba Wennberg, Rudy Bittar, Helena Svensson, John Paoli","doi":"10.5826/dpc.1502a5157","DOIUrl":"10.5826/dpc.1502a5157","url":null,"abstract":"<p><strong>Introduction: </strong>Thin invasive melanomas (Breslow thickness ≤1.0 mm) are increasing in incidence in Sweden, but notably also have a favorable prognosis. Treatment typically involves complete diagnostic excision followed by wide local excision (WLE) to eliminate potential microsatellite and satellite metastases along with residual melanoma.</p><p><strong>Objectives: </strong>This study aimed to investigate the frequency of microsatellite and satellite metastases in diagnostic excision specimens and residual melanoma in WLE specimens from thin melanomas.</p><p><strong>Methods: </strong>This was a retrospective cohort study including consecutively collected primary thin melanomas excised at Sahlgrenska University Hospital (Gothenburg, Sweden) between January 2014 and December 2020.</p><p><strong>Results: </strong>Among 1,012 cases, no microsatellites were observed in the diagnostic excisions. Meanwhile, macroscopic satellite metastases were only present in 0.2% of the cases (N=2). Among 887 melanomas undergoing WLE with available data (87.6%), no microsatellites or satellite metastases were found in the extra tissue removed. Of the completely excised melanomas (N=936, 92.5%), only 0.2% (N=2) exhibited residual melanoma in the WLE.</p><p><strong>Conclusions: </strong>Our findings align with previous studies suggesting that WLE may result in excessive and unnecessary treatment for completely excised thin melanomas. The requirement of performing WLEs following complete excision of thin melanomas needs to be reevaluated.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amelanotic Melanoma in Oculocutaneous Albinism: Clinical Presentation and Diagnostic Pitfalls with Dermoscopic-Histopathological Correlation.","authors":"Davide Gioco, Ilaria Girolami, Maria Angeles Gonzalez Inchaurraga, Cesare Massone, Simona Sola, Maria A Pizzichetta","doi":"10.5826/dpc.1502a4986","DOIUrl":"10.5826/dpc.1502a4986","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}