Dermatology practical & conceptual最新文献

{"title":"Topical Melatonin and Hair Graying Repigmentation: A Case Series.","authors":"Adrian Imbernon-Moya, Elena Alonso Delgado, Jiaying Xu, Francisco Hidalgo","doi":"10.5826/dpc.1603a6384","DOIUrl":"10.5826/dpc.1603a6384","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pigmented Purpura of Doucas and Kapetanakis in Pediatric Patients: A Rare Report of Six Cases.","authors":"Julia Nowowiejska-Purpurowicz, Vincenzo Piccolo, Dirk Van Gysel, Ramon Grimalt, Mario Cutrone","doi":"10.5826/dpc.1603a6241","DOIUrl":"10.5826/dpc.1603a6241","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557298/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopy of Capillary Malformations in Capillary Malformation-Arteriovenous Malformation Syndrome Type 2.","authors":"Inês Pereira Amaral, Ivânia Soares, Inês Tribolet Abreu, Madalena Pupo Correia, Filipe Monteiro, Joana Antunes","doi":"10.5826/dpc.1603a6663","DOIUrl":"10.5826/dpc.1603a6663","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperhidrotic and Hypertrichotic Cutaneous Plaque.","authors":"Pedro Simões Farinha, Beatriz Vilela, Alexandre João","doi":"10.5826/dpc.1603a6781","DOIUrl":"10.5826/dpc.1603a6781","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics of Patients Presenting with Moderate-to-Severe Atopic Dermatitis and Concomitant Inflammatory Bowel Diseases: a Multicenter Retrospective Study.","authors":"Elena Pezzolo, Maddalena Napolitano, Martina Maurelli, Caterina Foti, Vito Di Lernia, Michela Ortoncelli, Mariateresa Rossi, Cataldo Patruno, Maria Esposito, Niccolò Gori, Carlotta Gurioli, Ylenia Vallone, Francesca Peccerillo, Alessandro Armuzzi, Giampiero Girolomoni","doi":"10.5826/dpc.1603a6643","DOIUrl":"10.5826/dpc.1603a6643","url":null,"abstract":"<p><strong>Introduction: </strong>Atopic dermatitis (AD) and inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic immune-mediated disorders with overlapping immunopathogenic mechanisms. Limited research has investigated clinical features of AD and concomitant IBD.</p><p><strong>Objectives: </strong>This study aimed to evaluate the clinical presentation of adult patients with concomitant moderate-to-severe AD and IBD.</p><p><strong>Methods: </strong>Adult patients with moderate-to-severe AD and confirmed IBD were identified across 12 hospital-based dermatology centers between 2022 and 2024 by using electronic records.</p><p><strong>Results: </strong>Thirty-eight out of 4,236 (0.9%) patients with moderate-to-severe AD had verified IBD (19 CD and 19 UC), with a prevalence higher than that expected in the general Italian population (0.9% vs 0.41%). The mean age at AD diagnosis was 25 years, with AD preceding IBD diagnosis with a median interval of 10 years in 71% of cases. At the time of the study, 40% of CD patients and 63% of UC patients were in clinical remission. AD clinical presentation in patients with IBD was typical, with 68% of patients presenting with flexural phenotype, and associated with personal (34%) or family (40%) history of atopy.</p><p><strong>Conclusions: </strong>IBD is not frequent in AD patients, but the prevalence seems to be higher compared to the general population. AD occurring with IBD had a typical clinical presentation. Interestingly, occurrence of AD preceded IBD onset in most patients, putting dermatologists in the position to make early IBD diagnosis. However, no direct causal relationship can be drawn from these findings. Larger, controlled prospective studies are needed to clarify the relationship between AD and IBD.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interplay of Biological Treatment and Psychological Features in Patients with Psoriasis: A Real-Life Prospective Study.","authors":"Gaia Moretta, Tonia Samela, Alessia Provini, Gianluca Pagnanelli, Dario Graceffa, Diego Orsini, Viviana Lora, Antonio Giovanni Richetta, Annunziata Dattola, Simone Amato, Nicoletta Bernardini, Paola Tribuzi, Arianna Zangrilli, Martina Vultaggio, Luca Bianchi, Giacomo Caldarola, Eleonora De Luca, Clara De Simone, Domenico Giordano, Cinzia Masini, Mauro Bavetta, Stefania Lechiancole, Vincenzo Panasiti, Damiano Abeni","doi":"10.5826/dpc.1603a6163","DOIUrl":"10.5826/dpc.1603a6163","url":null,"abstract":"<p><strong>Introduction: </strong>Emotional dysregulation (ED), common among patients with psoriasis, leads to psychopathology and impairs treatment adherence.</p><p><strong>Objective: </strong>This study examined the changes in prevalence of ED in patients and its effects on illness perception, mental health, and quality of life (QoL) during one year of treatment with risankizumab.</p><p><strong>Method: </strong>ED, illness perception, general health, and QoL were measured at baseline, and at four, 16, and 52 weeks posttreatment in 58 patients with psoriasis.</p><p><strong>Results: </strong>Higher ED was associated with greater psychological distress and poorer QoL. Patients with higher levels of ED reported greater psychological distress, worse QoL, and higher symptom-related distress throughout treatment as compared to those with lower ones. Although both groups improved in terms of illness perception and clinical severity outcomes, patients with high ED consistently experienced worse subjective outcomes.</p><p><strong>Conclusion: </strong>ED is frequent in psoriasis patients and negatively affects mental health and QoL, despite clinical improvements in skin symptoms. Targeted psychological interventions may be necessary for patients who exhibit higher levels of emotional dysregulation to ensure comprehensive care and better long-term outcomes.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopy-Based AI Risk Scoring Enhanced Experienced Dermatologists' Decision-Making: a Large Retrospective Reader Study.","authors":"Laudine Janssen, Sofie Van Kelst, Heleen Cokelaere, Julie Terrasson, Julie De Smedt, Alexandre Bohyn, Bart Diricx, Jonas De Vylder, Tom Kimpe, Jorien Papeleu, Evelien Verhaeghe, Lieve Brochez, Marjan Garmyn","doi":"10.5826/dpc.1603a6981","DOIUrl":"10.5826/dpc.1603a6981","url":null,"abstract":"<p><strong>Introduction: </strong>The integration of artificial intelligence (AI) in dermoscopy is promising for diagnostic and management decisions.</p><p><strong>Objectives: </strong>This study aimed to assess the impact of a deep learning-generated AI risk score, based on dermoscopic images and metadata, on dermatologists' diagnostic accuracy, confidence, and management strategy for lesions suspicious of skin cancer.</p><p><strong>Methods: </strong>A neural network was developed using a database of dermoscopic images of benign and malignant skin lesions, including both proprietary and public data. In a multicenter, cross-sectional study, 104 experienced dermatologists, with a median dermoscopic experience of 10 years, evaluated batches from a test set of 922 skin lesions, including 577 benign (63%) and 345 malignant (37%) cases, resulting in a dataset comprising 9,198 observations. Each case was assessed before and after the AI-generated risk score. Key outcomes included accurate diagnosis, correct decision on malignancy, and management strategy.</p><p><strong>Results: </strong>Overall accuracy for correct diagnosis increased from 74.6% before AI to 81.6% after AI (95% confidence interval (CI): 3.8%-10.2%; P<0.001). Overall sensitivity for decision on malignancy increased from 91.7% before AI, to 97.6% after AI (95% CI: 2.9%-8.8%; P<0.001). The biggest increase in sensitivity was seen for melanoma and high-grade dysplastic naevi, from 79.0% before AI to 93.8% after AI (95% CI: 5.4%-24.4%; P=0.002). AI was significantly associated with choosing the correct management strategy (53.5% to 59.0%, 95% CI: 2.5%-8.5%; P<0.001).</p><p><strong>Conclusions: </strong>AI enhanced experienced dermatologists' decision-making, particularly for melanoma and high-grade dysplastic naevi. Future prospective studies should further explore AI's integration into routine clinical settings.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopic Hallmarks of Lymphomatoid Papulosis: A Case Series of Five Histopathologically Proven Lesions.","authors":"Caterina Mariarosaria Giorgio, Gabriella Brancaccio, Stefano Caccavale, Paola Vitiello, Giuseppe Argenziano, Gaetano Licata","doi":"10.5826/dpc.1603a6359","DOIUrl":"10.5826/dpc.1603a6359","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycosis Fungoides Characterized by Palmar-Plantar Keratosis and Exudation.","authors":"Huanhuan Qu, Fengming Chen, Lei Wang","doi":"10.5826/dpc.1603a6476","DOIUrl":"10.5826/dpc.1603a6476","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction.","authors":"","doi":"10.5826/dpc.1601a7994","DOIUrl":"10.5826/dpc.1601a7994","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}