Dermatology practical & conceptual最新文献_第2页

Are Tattoos Safe in Patients with Systemic Lupus Erythematosus? Results From a Single-Center Study.

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a230

Francesco Natalucci, Fulvia Ceccarelli, Licia Picciariello, Giulio Olivieri, Claudia Ciancarella, Cristiano Alessandri, Fabrizio Conti

{"title":"Are Tattoos Safe in Patients with Systemic Lupus Erythematosus? Results From a Single-Center Study.","authors":"Francesco Natalucci, Fulvia Ceccarelli, Licia Picciariello, Giulio Olivieri, Claudia Ciancarella, Cristiano Alessandri, Fabrizio Conti","doi":"10.5826/dpc.1404a230","DOIUrl":"10.5826/dpc.1404a230","url":null,"abstract":"Introduction: Systemic Lupus Erythematosus is a pleiotropic autoimmune disease with common skin involvement. To date, only one study has investigated tattoos safety in SLE patients.Objective: We performed a single-center study to evaluate the development of local and systemic complications after tattooing in a cohort of systemic lupus erythematosus (SLE) patients. Furthermore, we tried to identify SLE patients who had expressed the will to get a tattoo and why they decided not to.Methods: Consecutive SLE patients were asked to complete a questionnaire about tattoos, including their number, features, and side effects. Open questions were proposed to non-tattooed patients to describe why they did not have tattoos.Results: One hundred ninety-two SLE patients were enrolled [M/F 21/171; median age 41 years (IQR 18)]. Almost 50% of them had at least one tattoo. Seven patients (7.4%) referred adverse reactions to tattoos; interestingly, only one patient experienced a systemic reaction, specifically the occurrence of self-limiting lymphadenopathy. The main reason for not getting a tattoo was the diagnosis of SLE.Conclusions: Our results suggest the safety of tattoos in SLE patients, as demonstrated by a low prevalence of mild adverse events.","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment and Validity of Trichoscopy for Eyebrow Involvement in Lichen Planopilaris and Frontal Fibrosing Alopecia: A Case-Control Study.

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a277

Awatef Kelati, Wassim Halli, Soumiya Chiheb

{"title":"Assessment and Validity of Trichoscopy for Eyebrow Involvement in Lichen Planopilaris and Frontal Fibrosing Alopecia: A Case-Control Study.","authors":"Awatef Kelati, Wassim Halli, Soumiya Chiheb","doi":"10.5826/dpc.1404a277","DOIUrl":"10.5826/dpc.1404a277","url":null,"abstract":"Introduction: Few publications are available on eyebrow trichoscopy in patients with alopecia areata and frontal fibrosing alopecia (FFA).Objective: To investigate the validity of using trichoscopy to examine eyebrow involvement in patients with lichen planopilaris (LPP) and FFA.Methods: In this case-control study, 109 patients with eyebrow involvement in LPP and FFA (cases) and with acquired hair disorders of the eyebrows (controls) were included.Results: Trichoscopy was highly specific and sensitive for the diagnosis of LPP and FFA. Trichoscopic features significantly associated with LPP were peripilar scaling, peripilar pigmentation, broken hairs, peripilar white halos, diffuse empty follicles, and vellus hair. Localized peripilar erythema and empty follicles were significantly associated with the diffuse form of LPP and the zigzag type of FFA. Yellow dots, dystrophic hairs, hair regrowth in different directions, and diffuse empty follicles were associated with LPP activity and FFA severity.Limitations: The retrospective nature of the statistical analysis.Conclusions: Trichoscopy is a valid tool for evaluating eyebrow involvement in LPP and FFA. Thus, it could help increase the diagnostic accuracy and predict the prognosis of eyebrow hair loss at an early stage.","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11620180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical and Dermoscopic Characteristics of Cutaneous Chondroid Syringoma: A Systematic Review. 皮肤软骨瘤的临床和皮肤镜特征：系统回顾

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a237

Antonio Di Guardo, Charalampos G Balampanos, Luca Gargano, Domenico Giordano, Alessandro Capalbo, Flavia Persechino, Severino Persechino

{"title":"Clinical and Dermoscopic Characteristics of Cutaneous Chondroid Syringoma: A Systematic Review.","authors":"Antonio Di Guardo, Charalampos G Balampanos, Luca Gargano, Domenico Giordano, Alessandro Capalbo, Flavia Persechino, Severino Persechino","doi":"10.5826/dpc.1404a237","DOIUrl":"10.5826/dpc.1404a237","url":null,"abstract":"Introduction: Cutaneous chondroid syringoma (CS) is a rare benign mixed skin tumor originating from sweat glands. Despite its rarity, accurate diagnosis and management are crucial due to its potential for malignant transformation.Objective: This study aimed to provide comprehensive insights into the main features of cutaneous CS, encompassing its epidemiology, clinical presentation, and particularly, dermoscopic findings.Methods: A systematic review was conducted to identify relevant literature on CS up to November 2023. Data extraction included clinical and histopathological characteristics from case reports and small case series.Results: The systematic review identified 347 unique CS cases, predominantly benign. Clinical features included a predilection for the head and neck region, with variations in morphology observed. Dermoscopic patterns, although limited, revealed recurrent features aiding diagnosis. Malignant CS cases constituted a notable subset, exhibiting distinct clinical and histopathological features.Conclusion: Cutaneous chondroid syringoma presents with characteristic clinical and histopathological features, necessitating comprehensive diagnostic approaches. Dermoscopy emerges as a valuable tool, although further research is needed to establish definitive patterns. Treatment primarily involves wide local excision, with collaboration among clinicians essential for optimal management. Future studies are warranted to address existing knowledge gaps and enhance understanding of this rare skin neoplasm.","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11620009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trichoscopy For Eyelash Involvement in Lichen Planopilaris: A Pilot Prospective Study.

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a274

Kelati Awatef, Wassim Halli, Soumiya Chiheb

引用次数: 0

Review - Expert Opinion on Antibiotics and Antibiotic Resistance in Dermatology. 回顾--关于皮肤科抗生素和抗生素耐药性的专家意见。

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a282

Giuseppe Argenziano, Marco Ardigò, Giuseppe Micali, Maria Rita Nasca, Alessandra Scilletta, Linda Tognetti, Pietro Rubegni, Stefano Veraldi

{"title":"Review - Expert Opinion on Antibiotics and Antibiotic Resistance in Dermatology.","authors":"Giuseppe Argenziano, Marco Ardigò, Giuseppe Micali, Maria Rita Nasca, Alessandra Scilletta, Linda Tognetti, Pietro Rubegni, Stefano Veraldi","doi":"10.5826/dpc.1404a282","DOIUrl":"10.5826/dpc.1404a282","url":null,"abstract":"Introduction: Antibiotic resistance has become a serious, severe problem worldwide. This issue does not only relate to the use of systemic antibiotics but to topical ones as well, like systemic therapies and local treatment of skin and mucosal infections. Antiseptics, an alternative to the topical treatment with antibiotics of wounds and some inflammatory dermatological conditions, tend to be microbicidal and have a broader spectrum of antimicrobial activity than antibiotics. Among these, polyhexanide (PHMB) allows for the control of the infection while avoiding the development of resistance.Objectives: Recommendations on the rules of good clinical practice for the management of small wounds, burns and post-traumatic ulcerative wounds, impetigo or folliculitis in the initial stages, and acne.Methods: Literature review on the principal topical therapies for small wounds, injuries, impetigo, folliculitis, and acne and a proposal of innovative, highly-tolerated treatments.Results and conclusions: Given the abuse of topical antibiotics in dermatology, for the treatment of small wounds, injuries, localized folliculitis, impetigo, and acne, the use of alternative topical treatments like polyhexanide and Rigenase® is recommended.","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11620216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Palmoplantar Psoriasis Resistant to Adalimumab Successfully Treated with Bimekizumab.

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a244

Emanuele Trovato, Martina Dragotto, Eugenio Capalbo, Pietro Rubegni

引用次数: 0

Profiling of Toll-like Receptors and Related Signaling Mediators in the Pathogenesis of Morphea.

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a219

Hilal Ayvaz Celik, Nilgun Gurbuz, Ergin Turantepe, Mücahit Secme, Yavuz Dodurga

{"title":"Profiling of Toll-like Receptors and Related Signaling Mediators in the Pathogenesis of Morphea.","authors":"Hilal Ayvaz Celik, Nilgun Gurbuz, Ergin Turantepe, Mücahit Secme, Yavuz Dodurga","doi":"10.5826/dpc.1404a219","DOIUrl":"10.5826/dpc.1404a219","url":null,"abstract":"Introduction: Morphea, also known as localized scleroderma, is a rare fibrosing inflammatory disease of unknown pathogenesis.Objectives: Although the genetic basis for morphea is important, reports on the evaluation of Toll-like receptors (TLR) in this disease is quite limited. We aimed to evaluate TLR expression levels and serum IL-6, IL-17A, TGF-β1, FGF, and VEGF levels in patients with morphea and compare these results with healthy controls.Methods: The expression levels of TLRs in the lesional and non-lesional adjacent skin of patients with morphea and in normal skin of healthy controls were evaluated by RT-PCR, whereas serum levels of IL-6, IL-17A, TGF-β1, FGF, and VEGF were evaluated by ELISA.Results: Based on our findings, TLR1 gene expression increased 34.3-fold in the lesional skin of patients with morphea. In addition, IL-6, IL-17A, TGF-β, FGF, and VEGF were found to be higher in the blood samples of the patient group than in the healthy group.Conclusion: TLRs are important parts of the pathogenesis of morphea, and a better understanding of them will lead to more directed, effective treatments. We believe that this study will be important for pioneering TLR-targeted therapeutic approaches in the treatment of morphea in the future.","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scalp Porokeratosis: Dermoscopy Key Role in Unmasking a Hidden Condition.

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a248

Rosario Agüero, Cristián Navarrete-Dechent, Bengu Nisa Akay

引用次数: 0

Non-invasive Imaging Techniques for the Diagnosis of Chromoblastomycosis.

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a236

Giulio Cortonesi, Davide Cosetti, Mariano Suppa, Cyril Habougit, Jean-Luc Perrot, Elisa Cinotti

引用次数: 0

Efficacy And Safety Of Low-Dose Methotrexate In Generalized And Recalcitrant Lichen Planus: A Retrospective Study At A Tertiary Care Center.

IF 2.5 4区医学

Dermatology practical & conceptual Pub Date : 2024-10-30 DOI: 10.5826/dpc.1404a220

Ananta Khurana, Savitha Sharath, Kabir Sardana

{"title":"Efficacy And Safety Of Low-Dose Methotrexate In Generalized And Recalcitrant Lichen Planus: A Retrospective Study At A Tertiary Care Center.","authors":"Ananta Khurana, Savitha Sharath, Kabir Sardana","doi":"10.5826/dpc.1404a220","DOIUrl":"10.5826/dpc.1404a220","url":null,"abstract":"Introduction: Methotrexate (MTX) acts by suppressing multiple immune pathways involved in the pathogenesis of lichen planus (LP). Trials assessing the efficacy and relapse rates of methotrexate in LP are lacking.Objectives: Our objective was to analyze the efficacy and safety of low-dose methotrexate in generalized and recalcitrant LP patients retrospectively and to assess the relapse rates in patients after stopping MTX therapy.Methods: We analyzed clinical and therapeutic details of LP patients treated with low-dose MTX at our center. The cumulative dose and duration of MTX was calculated, and the time to achieve disease control was noted. We analyzed duration of remission and time after which recurrences were seen post-treatment.Results: Records of 42 generalized and recalcitrant LP patients treated with MTX were analyzed. The starting dose of MTX was 7.5 mg (n=7) or 10 mg (n= 35) once weekly, increased to 10/15 mg weekly in patients with inadequate response. Ten patients were lost to follow-up. Complete resolution was achieved in 30/32 (93%) patients within a mean duration of 14.76 weeks (4-32 weeks), and the cumulative dose of MTX to achieve remission was 153.58 mg (50-375 mg). Only minor side effects were noted in 12/32 (37.5%) patients, and none required treatment discontinuation. The mean duration of remission was 29.43 months (5-60 months).Conclusion: MTX demonstrated high efficacy and a good safety profile in extensive cutaneous LP and may be a safer alternative to steroids for this condition.","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0