Dermatology practical & conceptual最新文献_第2页

Keratotic Spicules in Lichen Scrofulosorum: A Novel Dermoscopic Clue. 阴囊地衣的角化性针状体：一种新的皮肤镜线索。

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a7024

Mariem Tabka, Hicham Mokhtari, Maissa Lajhouri, Mohammad Azouagh, Asmahane Souissi, Mourad Mokni

引用次数: 0

Evaluation of Stress, IL-18, and IL-22 Levels and Their Interrelationships in Patients with Seborrheic Dermatitis. 脂溢性皮炎患者应激、IL-18和IL-22水平及其相互关系的评估

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a7150

Lütfi Işık, Müzeyyen Gönül, Selda Pelin Kartal, Funda Güçel

{"title":"Evaluation of Stress, IL-18, and IL-22 Levels and Their Interrelationships in Patients with Seborrheic Dermatitis.","authors":"Lütfi Işık, Müzeyyen Gönül, Selda Pelin Kartal, Funda Güçel","doi":"10.5826/dpc.1603a7150","DOIUrl":"10.5826/dpc.1603a7150","url":null,"abstract":"Introduction: Seborrheic dermatitis (SD) is a chronic inflammatory dermatosis with multifactorial pathogenesis. Cytokines such as IL-18 and IL-22 are implicated in inflammatory and stress-related pathways, but their roles in SD remain unclear.Objectives: To investigate serum IL-18 and IL-22 levels in SD patients, evaluate their relationship with disease severity and perceived stress, and explore their potential relevance to SD pathophysiology.Methods: In this cross-sectional study, 46 SD patients and 42 healthy controls were included. Disease severity was assessed using the Seborrheic Dermatitis Area Severity Index, and stress with the Perceived Stress Scale-10. Serum cytokine levels were measured by ELISA. Group comparisons and correlation analyses between cytokines, disease severity, and stress were performed.Results: Patients had significantly higher stress scores than controls (mean 19.8 ± 4.6 vs 13.7 ± 4.2). Serum IL-22 levels were elevated in SD (median 369.3 vs 143.1 pg/mL; P<0.001). A cutoff of 202.8 pg/mL for IL-22 distinguished patients from controls, with 100% sensitivity and 97.6% specificity. IL-18 levels did not differ significantly between groups. IL-18 and IL-22 showed a moderate negative correlation (r=-0.409; P=0.005). Stress scores correlated positively with disease severity (r=0.336; P=0.022), and IL-22 correlated with stress across all participants (r=0.541; P<0.001).Conclusions: Elevated serum IL-22 levels observed in patients with SD suggest a possible involvement of IL-22 in SD-related inflammatory processes. The observed associations between IL-22 and perceived stress support a potential interaction between immunological and psychosocial factors in SD. These findings should be considered exploratory and warrant confirmation in larger studies.","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Demodex Folliculitis Following Anifrolumab Infusion. 滴注无性菌抗体后蠕形螨性毛囊炎。

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a6923

Hannah Bulosan, Lisa Maier, Andrea Kalus

引用次数: 0

Impact of Isotretinoin Therapy on Thyroid Hormone Levels in Patients with Acne Vulgaris: A Systematic Review and Meta-Analysis. 异维甲酸治疗对寻常痤疮患者甲状腺激素水平的影响：一项系统综述和荟萃分析。

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a7403

Mishari Tariq Alrubaiaan, Ajlan Hashim Alajlani, Raneem Alwatban, Abdulelah Nabil Alkadi, Hawra Fahad Alkhodairy, Fatimah Moayed Alalwan, Sarah Waleed Bin Rashid, Waleed Alajroush

{"title":"Impact of Isotretinoin Therapy on Thyroid Hormone Levels in Patients with Acne Vulgaris: A Systematic Review and Meta-Analysis.","authors":"Mishari Tariq Alrubaiaan, Ajlan Hashim Alajlani, Raneem Alwatban, Abdulelah Nabil Alkadi, Hawra Fahad Alkhodairy, Fatimah Moayed Alalwan, Sarah Waleed Bin Rashid, Waleed Alajroush","doi":"10.5826/dpc.1603a7403","DOIUrl":"10.5826/dpc.1603a7403","url":null,"abstract":"Introduction: Systemic isotretinoin is extensively used to treat moderate-to-severe acne vulgaris and may have systemic endocrine effects through the hypothalamic-pituitary-thyroid axis.Objectives: To investigate the changes in thyroid hormone levels after commencement of systemic isotretinoin among patients with acne vulgaris.Methods: A PubMed, ScienceDirect, Scopus, and Cochrane Library search was performed. Pooled analysis was conducted utilizing Review Manager (RevMan 5.4.1).Results: A total of 447 patients from eight observational studies were included. After three and four months, no increase in TSH levels was observed following isotretinoin treatment with a standardized mean difference (SMD) of 0.09 (95% CI: -0.27-0.46; P=0.62) and (SMD=0.72; 95% CI: -0.01-1.45; P>0.05), respectively. However, a significant increase in TSH levels was observed at six months (SMD=0.54; 95% CI: 0.05-1.03; P=0.03). T4 levels showed no alteration at three months (SMD= -0.24; 95% CI: -0.56-0.08; P=0.14) but were reduced at four months (SMD= -0.79; 95% CI: -1.20--0.38; P=0.0001) and six months (SMD= -0.87; 95% CI: -1.57--0.17; P=0.01). T3 levels were reduced at three months (SMD= -0.42; 95% CI: -0.80--0.04; P=0.03), four months (SMD=-0.63; 95% CI: -1.03--0.23; P=0.002), and 6 months (SMD= -1.13; 95% CI: -1.77--0.55; P=0.0001).Conclusion: Long-term isotretinoin treatment may cause time-dependent changes in thyroid hormone levels.","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sherlock Holmes In Dermatology: Solving Diagnostic Mysteries With Ultraviolet Light. 夏洛克·福尔摩斯在皮肤病学：用紫外线解开诊断之谜。

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a7080

Milos Nisavic, Aleksandra Bukvic Sajinovic, Danica Tiodorovic

引用次数: 0

Research Letter Down Syndrome and Thyroid Disease as Joint Risk Factors for Atopic Dermatitis: A Nationwide Cohort Analysis. 唐氏综合征和甲状腺疾病是特应性皮炎的共同危险因素：一项全国性队列分析。

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a7088

Kevin W Hoffman, Malay Shah, James Madsen, Tejas P Joshi, Vicky Ren

引用次数: 0

Tunisian Endemic Pemphigus Foliaceus is a Real Entity with Distinctive Epidemiological, Genetic, and Environmental Features. 突尼斯地方性叶状天疱疮是一种具有独特流行病学、遗传和环境特征的真实实体。

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a7044

Hatem Masmoudi, Hamida Turki, Olfa Abida, François Tron

引用次数: 0

Reply to "Scabies Treatment Failure: Beyond Permethrin and Plastic Bags". 回复“疥疮治疗失败：超越氯菊酯和塑料袋”。

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a6648

Vanessa Azzolina, Franziska Schauer, Julia Felicitas Pilz, Alexander Zink, Kilian Eyerich, Anna Caroline Pilz

引用次数: 0

Evaluation of Fibromyalgia Frequency in Chronic Spontaneous Urticaria Patients Referred to a Tertiary Dermatology Outpatient Clinic. 评价纤维肌痛频率在慢性自发性荨麻疹患者转介三级皮肤科门诊。

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a6659

Fatma Etgü, Derya Çırakoğlu

{"title":"Evaluation of Fibromyalgia Frequency in Chronic Spontaneous Urticaria Patients Referred to a Tertiary Dermatology Outpatient Clinic.","authors":"Fatma Etgü, Derya Çırakoğlu","doi":"10.5826/dpc.1603a6659","DOIUrl":"10.5826/dpc.1603a6659","url":null,"abstract":"Introduction: Chronic spontaneous urticaria (CSU) and fibromyalgia (FM) share overlapping features such as autoimmunity, psychological influence, and female predominance. Previous studies show conflicting results on FM prevalence in CSU patients.Objectives: This study aimed to assess the prevalence of concurrent FM in patients with CSU.Methods: A cross-sectional study including 257 CSU patients and age- and sex-matched healthy controls. Data collected included demographics, disease duration, severity (UAS-7), and quality of life (DLQI). FM was diagnosed using the 2016 ACR criteria.Results: The prevalence of FM was 18.98% in CSU patients and 4.43% for the control group (P<0.01). The mean WPI and SSS scores were higher in the CSU group; WPI was statistically significant (P < 0.01), whereas SSS showed no statistically significant difference (P = 0.05). CSU patients with FM had longer disease duration, higher disease severity, and more impairment in life. Furthermore, female CSU patients had more FM than did male CSU patients (P<0.001).Conclusions: FM was more prevalent among patients with CSU compared to the control group. Female sex, higher disease severity, and impaired quality of life were significantly associated with FM in CSU patients. Given the reduced quality of life observed in individuals with both conditions, clinicians should consider evaluating CSU patients, especially those with severe symptoms, for FM to ensure accurate diagnosis and comprehensive management. Further studies are needed to clarify the nature of this association.","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subungual Glomus Tumor Managed with Nd: YAG Laser: A Case Report with Clinical and Ultrasonographic Follow-Up. Nd: YAG激光治疗掌下血管球瘤1例临床及超声随访。

IF 2.4 4区医学

Dermatology practical & conceptual Pub Date : 2026-07-31 DOI: 10.5826/dpc.1603a7237

Valeria Duque-Clavijo, Maria Alejandra Sánchez, Claudia González, Hernán Duque-Romero

引用次数: 0