心理因素对早发性与晚发性银屑病影响的比较分析

IF 2.3 4区 医学 Q2 DERMATOLOGY
E Elif Afacan Yıldırım, Muhterem Polat
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引用次数: 0

摘要

简介:牛皮癣是一种慢性炎症性疾病,显著影响社会心理健康。本研究比较了早发性牛皮癣的临床和社会心理特征(方法:本横断面研究纳入190例早发性(n=135)和晚发性(n=55)牛皮癣患者。收集了人口统计学、临床特征、合并症和社会心理因素的数据。医院焦虑抑郁量表(HADS)和皮肤科生活质量指数(DLQI)评估心理影响和生活质量。统计分析包括卡方检验、t检验和相关分析。结果:早发患者有银屑病家族史的可能性更大(43.7% vs. 16.4%)。结论:早发性银屑病患者更有可能将压力作为诱因并有家族史,而晚发性银屑病患者表现出更高的脓疱性银屑病发病率和更高的体重指数。早发性慢性斑块型银屑病患者有更大的心理负担,尤其是焦虑。这些发现强调了发病年龄在牛皮癣护理中定制社会心理支持和治疗策略的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of Psychological Factors on Early vs. Late-Onset Psoriasis: A Comparative Analysis.

Introduction: Psoriasis is a chronic inflammatory disease that significantly impacts psychosocial well-being. This study compared the clinical and psychosocial characteristics of early-onset (<40 years) and late-onset (≥40 years) psoriasis.

Methods: This cross-sectional study included 190 patients with psoriasis categorized as early-onset (n=135) and late-onset (n=55). Data on demographics, clinical features, comorbidities, and psychosocial factors were collected. The Hospital Anxiety and Depression Scale (HADS) and the Dermatology Life Quality Index (DLQI) assessed psychological impact and quality of life. Statistical analyses included chi-squared tests, t-tests, and correlation analyses.

Results: Early-onset patients were more likely to have a family history of psoriasis (43.7% vs. 16.4%, P<0.001), while pustular psoriasis was more common in the late-onset group (27.3% vs. 11.1%, P=0.006). A significant positive correlation was observed between DLQI scores and HADS-Total, HADS-Anxiety, and HADS-Depression scores (P<0.001). Psychological stress was reported as a disease trigger by 63.1% of patients, with a higher proportion in the early-onset group (P=0.025). Although initial comparisons revealed no significant difference in DLQI or HAD scores between groups, an additional analysis limited to chronic plaque psoriasis revealed significantly higher anxiety and total HADS scores in the early-onset group (P=0.002 and P=0.035, respectively), suggesting a stronger psychological burden when clinical subtype is controlled.

Conclusions: Early-onset psoriasis patients are more likely to report stress as a trigger and have a family history, while late-onset patients exhibit higher rates of pustular psoriasis and increased body mass index. Early-onset patients with chronic plaque psoriasis experience greater psychological burden, particularly anxiety. These findings highlight the importance of age of onset in tailoring psychosocial support and treatment strategies in psoriasis care.

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CiteScore
1.40
自引率
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发文量
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