Dermatology practical & conceptual最新文献

{"title":"Correlation of Psychosomatic Factors and Personality Traits with The Severity of Hidradenitis Suppurativa.","authors":"Konstantinos Kontoangelos, Foteini Dionysia Foulou, Sofia Tsiori, Charalabos Papageorgiou, Alexander Stratigos, Aikaterini I Liakou","doi":"10.5826/dpc.1404a4566","DOIUrl":"10.5826/dpc.1404a4566","url":null,"abstract":"<p><strong>Introduction: </strong>Hidradenitis suppurativa is a disease with a decisive burden on sufferers, both physical and psychological. It was expected that the more intense the severity of symptoms the patients experienced, the greater the correlation with the psychosomatic manifestations would be.</p><p><strong>Objectives: </strong>The present study aimed to explore the correlation between hidradenitis suppurativa and the psychosomatic burden, the personality, and the demographic characteristics of the participants.</p><p><strong>Methods: </strong>The participants were 90 outpatients of the hospital, aged 18 to 65, who had been diagnosed with hidradenitis and were sufficiently proficient in Greek. The psychometric instruments administered were the Symptom Checklist-90 (SCL90), the Beck Depression Inventory (BDI), the Eysenck Personality Questionnaire (EPQ), the short-form McGill Pain Questionnaire (SF-MPQ), the Hurley and refined Hurley classifications, the International Hidradenitis Suppurativa Severity Scoring System (IHS4), and a short demographic questionnaire. All statistical analyses were performed using the SPSS-28 statistical package.</p><p><strong>Results: </strong>According to statistical analyses, there was no statistically significant relationship between disease severity, psychosomatic burden, and personality. However, there were statistically significant associations with demographic factors, such as being female or not being in a relationship, the patient's body mass index, the locus of the skin lesion, a history of hospitalization, comorbidities, psychiatric history, and pain with psychopathological manifestations and personality.</p><p><strong>Conclusions: </strong>It is important that further research be conducted that will include more mental disorders besides anxiety and depression while at the same time excluding confounding factors for safer interpretation of the results.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attitudes and Behaviors Regarding Sun Exposure of the Italian Population.","authors":"Vincenzo Piccolo, Charles Taïeb, Marketa Saint Aroman, Catherine Baissac, Eleonora Cinelli, Giuseppe Argenziano","doi":"10.5826/dpc.1501a4650","DOIUrl":"10.5826/dpc.1501a4650","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological, Clinical, Dermoscopic Findings, and Management of Perinevoid Alopecia.","authors":"Cintia Medeiros Martins, Daniel Fernandes Melo, Hugo Monteiro Faver, Michela Starace, José Leonardo Rodrigues Machado, Carla Jorge Machado, Rita Fernanda Cortez de Almeida","doi":"10.5826/dpc.1501a4742","DOIUrl":"10.5826/dpc.1501a4742","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Melasma and Its Effect on Quality of Life: A Cross-Sectional Perspective.","authors":"Reza Almasi Ghale, Maryam Nasimi, Saeideh Alidoost, Marjan Talebi, Rouzbeh Almasi Ghale, Mehregan Rahmani, Farkhondeh Pouresmaeili","doi":"10.5826/dpc.1501a4601","DOIUrl":"10.5826/dpc.1501a4601","url":null,"abstract":"<p><strong>Introduction: </strong>Melasma is a skin disorder that causes brown spots on the face, especially in females and people with dark skin. This situation can have a significant impact on the patient's quality of life, including issues with self-confidence, mental strain, and difficulty in social and familial relationships.</p><p><strong>Objectives: </strong>This study aimed to evaluate the quality of life of patients with melasma.</p><p><strong>Methods: </strong>We conducted a study analyzing the relationship between the severity of melasma and quality of life using the Dermatology Life Quality Index (DLQI) questionnaire.</p><p><strong>Results: </strong>The study found that severity of melasma, which was measured by the Melasma Area and Severity Index (MASI), was closely related to the degree of maximum darkness in the affected area. The researchers also found a modest impact on quality of life related to the condition, with DLQI scores averaging 6.16, and a strong correlation between MASI scores and quality of life.</p><p><strong>Conclusions: </strong>Healthcare professionals should also consider the emotional and societal consequences of skin pigmentation conditions in addition to providing medical and therapeutic interventions. Further research is needed to better understand the complex relationships between different factors and their impact on skin health.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopic Features of Anogenital Verrucous Carcinoma.","authors":"Enrico Zelin, Giuseppe Stinco, Marco Turina, Enzo Errichetti","doi":"10.5826/dpc.1501a4655","DOIUrl":"10.5826/dpc.1501a4655","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopy of Vitiligo and Other Hypopigmented Skin Lesions in Indian Patients: A Cross-Sectional Study.","authors":"Ananya Sharma, Binod K Khaitan, Vishal Gupta, M Ramam, Kanika Sahni","doi":"10.5826/dpc.1501a4648","DOIUrl":"10.5826/dpc.1501a4648","url":null,"abstract":"<p><strong>Introduction: </strong>Non-vitiligo hypopigmented skin lesions may be close clinical mimickers of vitiligo, resulting in a diagnostic dilemma. Dermoscopic features of vitiligo have been studied, but those of other hypopigmentation disorders are not well-characterized.</p><p><strong>Objectives: </strong>We aimed to describe and compare the dermoscopic features of vitiligo and other hypopigmented skin lesions.</p><p><strong>Methods: </strong>This was a cross-sectional study including 105 vitiligo and 137 other hypopigmented skin lesions, including ash-leaf macules (N=17), nevus depigmentosus (N=16), post-inflammatory hypopigmentation (N=16), pityriasis alba (N=15), pityriasis versicolor (N=14), idiopathic guttate hypomelanosis (IGH) (N=14), lichen sclerosus (N=12), leprosy (N=9), and others. Dermoscopic findings were recorded by concordance of at least two qualified dermatologists.</p><p><strong>Results: </strong>Common dermoscopic findings in vitiligo were intermediate or ill-defined margins (96/105, 91.4%) and a complete absence of pigment network (70/105, 66.7%). Nevus depigmentosus lesions were mostly hypopigmented, with a faint pigment network throughout the lesion. In 15/17 (88.2%) ash-leaf macules, a characteristic pattern of sharply demarcated areas of normal pigment network was seen within a depigmented lesion. Almost all lesions of IGH had a sharply defined margin with completely absent pigment network; discernible eccrine openings within the lesion were seen in 9/14 (64.3%). Dermoscopic findings of a complete absence of pigment network, perifollicular retention of pigment, presence of vascular pattern, loss of discernibility of eccrine openings within the lesion, and lack of scaling were statistically significantly more common in vitiligo than other hypopigmented skin lesions (P <0.001).</p><p><strong>Conclusion: </strong>Vitiligo, nevus depigmentosus, ash-leaf macule, and IGH have distinctive dermoscopic features. Dermoscopy can aid in the differential diagnosis of vitiligo and other hypopigmented skin lesions.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geriatric Psoriasis: Evaluation of Clinical Features, Disease Course, and Treatment Modalities of Patients from a Tertiary Care Hospital.","authors":"Elif Çalışkan, Yusuf Can Edek, Nuray Keskin, Petek Üstün, Esra Adışen","doi":"10.5826/dpc.1501a4511","DOIUrl":"10.5826/dpc.1501a4511","url":null,"abstract":"<p><strong>Introduction: </strong>Psoriasis is an inflammatory skin disease characterized by erythematous, scaly, pruritic plaques on the extensor areas of the extremities. It is one of the most common dermatological diseases in the geriatric population.</p><p><strong>Objective: </strong>The aim of this investigation was to evaluate the demographic data, clinical characteristics, and treatment responses of the geriatric population (≥65 years) with psoriasis at our hospital.</p><p><strong>Methods: </strong>In this study, we examined 160 geriatric patients diagnosed with psoriasis. We evaluated patients in two groups: early onset (EaO) (<60 years) and elderly onset (EO) (≥60 years).</p><p><strong>Results: </strong>In our study, 53.8% of the patients were male, the average age was 68.7 years, and 65% of the patients were considered EaO. Knee and elbow lesions were detected more frequently at the beginning and during the disease in the EaO group; 44.4% of patients had nail psoriasis, while 20.6% had psoriatic arthritis. Nail involvement (P = 0.17) and the presence of psoriatic arthritis (P = 0.035) were more common in the EaO group. Erythrodermic psoriasis was more common in the EaO group, but it was not statistically significant (P = 0.097). It was observed that the disease course of psoriasis was slower in the EaO group compared to the EO group (P = 0.001). Systemic treatment was predominantly initiated as the first treatment agent in the EO group (P = 0.006). Patients in the EaO group received more cyclosporine treatment than the others (P = 0.004).</p><p><strong>Conclusions: </strong>The geriatric population is associated with multiple comorbidities and polypharmacy, highlighting the importance of evaluating patients' medications and comorbidities when selecting a treatment agent for psoriasis.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Trichoscopic Evaluations of Topical Finasteride 1%, Topical Spironolactone 5%, and Minoxidil 5% in Female Pattern Hair Loss Treatment.","authors":"Naglaa Mohamad Al Sayed, Eman Hamed El Morsy, Tarek Mahmoud Hussein, Eman Mohamed Hassan","doi":"10.5826/dpc.1501a4698","DOIUrl":"10.5826/dpc.1501a4698","url":null,"abstract":"<p><strong>Introduction: </strong>Female pattern hair loss (FPHL) is one of the most common forms of diffuse alopecia in females. Despite the availability of multiple treatment options, FPHL management poses challenges for the dermatologist.</p><p><strong>Objectives: </strong>We aimed to compare the efficacy and safety of topical finasteride 1% solution and spironolactone 5% solution to minoxidil 5% solution in the treatment of FPHL clinically and trichoscopically.</p><p><strong>Methods: </strong>Forty-five adult female patients diagnosed with FPHL were divided into three groups of 15 each. Group A was treated with topical finasteride 1%, group B used topical spironolactone 5%, and group C was treated with topical minoxidil solution 5 %, all groups were treated for 16 weeks.</p><p><strong>Results: </strong>By the end of 16th week, significant improvement on the Sinclair scale was observed in groups A and C, but the difference between the three groups was statistically insignificant. Trichoscopically, hair density significantly increased in groups A and C. There was a significant reduction in the number of patients with yellow dots, peripilar sign, and single hair follicular units (FU) in group A. In group C, a significant reduction in the number of patients with yellow dots and single hair FU was documented. No trichoscopic changes were detected in group B.</p><p><strong>Conclusions: </strong>Topical finasteride is as safe and effective as topical minoxidil in FPHL. Both treatments showed greater effectiveness clinically and trichoscopically than topical spironolactone. The use of topical finasteride may be another solution for the treatment of FPHL in minoxidil non-responders or in the presence of intolerable side effects.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combination of Cemiplimab and Radiotherapy in Advanced Squamous Cell Carcinoma.","authors":"André Aparício Martins, João Teixeira, Ricardo Vieira, Inês Coutinho","doi":"10.5826/dpc.1501a4814","DOIUrl":"10.5826/dpc.1501a4814","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatological Manifestations and Sebum Composition in Parkinson's Disease.","authors":"Meshi Paz, Peter Lio","doi":"10.5826/dpc.1501a4921","DOIUrl":"10.5826/dpc.1501a4921","url":null,"abstract":"<p><strong>Introduction: </strong>Parkinson disease (PD) is a multifaceted neurodegenerative disorder known for its hallmark motor symptoms. However, nonmotor manifestations, specifically dermatological changes, precede motor symptoms and may thus serve as vital early indicators of PD.</p><p><strong>Objectives: </strong>This article explores the skin-related changes associated with PD, focusing on alterations in sebum composition, microbial dysbiosis, and the potential for leveraging dermatological assessments as early, noninvasive diagnostic markers for PD.</p><p><strong>Methods: </strong>A comprehensive literature review was conducted to investigate dermatological manifestations of PD, focusing on sebum changes in affected individuals. Research explored the clinical relevance of altered lipid profiles, volatile organic compound (VOC) contributions, and microbiome dysbiosis in those with PD.</p><p><strong>Results: </strong>Individuals with PD exhibit excess sebum production characterized by altered lipid profiles, including elevated short-chain fatty acids (SCFAs) and disruptions in sphingolipid metabolism. The lipid-rich environment also promotes overgrowth of Malessezia yeast, contributing to varied dermatological symptoms in those with PD. VOCs identified in sebum have been linked to unique odors and serve as biomarkers for diagnostic potential. These findings support the potential for early PD diagnosis through dermatologic assessment and sebum analysis.</p><p><strong>Conclusion: </strong>Dermatological manifestations in PD offer promising noninvasive biomarkers for early diagnosis. Future research should aim to further elucidate the mechanisms underlying sebum dysregulation in PD and validate the clinical relevance of these biomarkers in larger populations.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11928091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}