Dermatology practical & conceptual最新文献

{"title":"Epidemiology and Severity of Prurigo Nodularis in Europe: A Literature Review with an Application to Italian Data.","authors":"Cataldo Patruno, Claudio Pelucchi, Carlotta Galeone, Martino Emmi, Paolo Amerio","doi":"10.5826/dpc.1502a4716","DOIUrl":"10.5826/dpc.1502a4716","url":null,"abstract":"<p><strong>Introduction: </strong>Prurigo nodularis is a chronic inflammatory skin disease with recent definition and relatively low prevalence. Information on prurigo nodularis, including its epidemiology, severity, and burden of disease, is still scanty.</p><p><strong>Objectives: </strong>We sought to review and summarize recent quantitative data on prurigo nodularis in Europe and to estimate the burden of disease in Italy, with a focus on moderate-to-severe prurigo nodularis.</p><p><strong>Methods: </strong>We conducted a systematic literature review of recent studies on the epidemiology of prurigo nodularis in Europe, using PubMed/MEDLINE and EMBASE. The study selection process was conducted independently by two reviewers. Articles focusing on the severity of prurigo nodularis were also searched (non-systematically), and relevant information was extracted. Synthetic results were combined to population data to derive the best estimate of the burden of prurigo nodularis in Italian adults.</p><p><strong>Results: </strong>Five articles reporting data on incidence and/or prevalence of prurigo nodularis in European populations were identified. The prevalence of prurigo nodularis ranged from 6.5 to 111.0 cases per 100,000, with a median estimate of 32.7 cases per 100,000, the incidence ranging between 2.88 and 20 per 100,000 person-years. Five other studies reported data on the severity of prurigo nodularis, measured through pruritus scores, quality-of-life indexes and/or percentage of non-response to treatment. We estimated a total of 16,280 prevalent prurigo nodularis cases in Italy, of whom 6,073 had moderate-to-severe to very severe disease. Among the latter, 1,798 estimated cases were not controlled by standard treatments.</p><p><strong>Conclusions: </strong>We retrieved and summarized recent epidemiological data on prurigo nodularis, evidencing a high burden of disease in Italy and other European countries.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopy of a Rare Case of Porokeratotic Eccrine Ostial and Dermal Duct Nevus.","authors":"Ranjana Beniwal, Akriti Agrawal","doi":"10.5826/dpc.1502a4997","DOIUrl":"10.5826/dpc.1502a4997","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"International Survey on Dermoscopic Image Management: ISIC Data on Capture, Storage, and AI Integration in Dermatology.","authors":"Aarthi Parvathaneni, Madison M Taylor, T Austin Black, Kelly C Nelson","doi":"10.5826/dpc.1502a4896","DOIUrl":"10.5826/dpc.1502a4896","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Perioral Dermatitis Associated with Inhaled Corticosteroids: A Retrospective Case Series.","authors":"Tullio Brunetti, Marco Adriano Chessa, Miriam Leuzzi, Carlotta Gurioli, Stephano Cedirian, Iria Neri","doi":"10.5826/dpc.1502a5239","DOIUrl":"10.5826/dpc.1502a5239","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Tunisian Endemic Pemphigus Foliaceus A Real Entity, Or Should These Cases Be Reclassified With Other Autoimmune Blistering Disease?","authors":"Ana Maria Abréu-Vélez, Willy Ramos, Michael S Howard","doi":"10.5826/dpc.1502a5008","DOIUrl":"10.5826/dpc.1502a5008","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Scabies: Association with Sleep Disorders, Anxiety, Depression, and Impaired Quality of Life.","authors":"Nihal Sarı, Gülsüm Yitik Tonkaz, Şeyda Arslan","doi":"10.5826/dpc.1502a4979","DOIUrl":"10.5826/dpc.1502a4979","url":null,"abstract":"<p><strong>Introduction: </strong>Scabies is a contagious, infectious skin disease that is observed worldwide. Scabies affects individuals of all ages, although it exhibits significant differences between childhood and adulthood. While the number of publications documenting the co-occurrence of anxiety, depression, and impaired quality of life (QoL) in adult patients with scabies is increasing, the presence of these issues in pediatric patients remains a topic of curiosity.</p><p><strong>Objectives: </strong>In this study, we aimed to investigate the presence of sleep disorders, QoL, anxiety, and depression in children with scabies.</p><p><strong>Methods: </strong>In this analytical case-control study, 68 scabies patients and 69 healthy controls aged 6-17 years were included.</p><p><strong>Results: </strong>In patients with scabies, sleep quality was significantly poorer compared to the control group (P<0.001). There was no difference between the two groups in terms of RCADS (Revised Children's Anxiety and Depression Scale) and total anxiety and depression scores. In the control group, the number of individuals with upper and upper-middle socioeconomic levels was higher (P=0.036). A moderate correlation was found between impairment in dermatology-related QoL and deterioration in sleep quality in patients with scabies (r=0.606, P<0.001).</p><p><strong>Conclusion: </strong>This study found that sleep disorders are common among children diagnosed with scabies, negatively impacting their QoL compared to healthy controls. We believe that obtaining information about both night and day sleep patterns during dermatological follow-ups of children diagnosed with scabies and providing recommendations on sleep hygiene as part of the treatment process may have positive effects on a child's QoL.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reactive Eccrine Syringofibroadenoma Associated with Neuropathy and Diabetic Foot Ulcer.","authors":"Yusuf Can Edek, Hale Nur Ertugay Aral, Meral Toker, Betül Öğüt, Esra Adışen","doi":"10.5826/dpc.1502a5230","DOIUrl":"10.5826/dpc.1502a5230","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of Osteoporosis Associated with Glucocorticoid Use in Pemphigus Vulgaris: Insights from a Retrospective Cohort Study.","authors":"Merve Kaya, Gülhan Aksoy Saraç, Onur Acar, Selma Emre, Akın Aktaş","doi":"10.5826/dpc.1502a5050","DOIUrl":"10.5826/dpc.1502a5050","url":null,"abstract":"<p><strong>Introduction: </strong>Pemphigus vulgaris (PV) is an autoimmune bullous disease affecting the skin and mucous membranes. Osteoporosis, a significant side effect of commonly used glucocorticoids in treatment, can adversely contribute to the existing morbidity.</p><p><strong>Objectives: </strong>This study aimed to assess the impact of glucocorticoid therapy on bone mineral density in patients with PV.</p><p><strong>Methods: </strong>Patients newly diagnosed with PV were included in this study. Femur and lumbar T-scores, serum calcium, vitamin D, alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) levels were analyzed before and one year after therapy.</p><p><strong>Results: </strong>Among 66 patients, the average time to diagnosis was 10.14 months, and the average daily dose of prednisone was 16.95 mg, with 63.6% of patients receiving medium doses. Our data showed no significant change in lumbar T-scores after one year of glucocorticoid treatment, but a significant decrease in femur density was observed. The decrease in femur T-scores was significant in the medium-dose group, while the lumbar T-scores decreased significantly in the high-dose group. There was no significant correlation between T-scores and sex, menopausal state, diagnosis time, or obesity. Additionally, vitamin D and LDH levels significantly increased after treatment, while changes in serum calcium and ALP levels were not significant.</p><p><strong>Conclusion: </strong>Given the multiple factors that reduce bone mineral density in PV patients, the current strategies for glucocorticoid-induced osteoporosis prophylaxis in this group may need re-evaluation, with potential for additional recommendations to be included in pemphigus guidelines.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Outcomes of Surgical and Chemical Matricectomy for Ingrown Toenail Management: A Retrospective Study.","authors":"Ayda Acar, Ayris Ozturk, Berke Kokluce, Bengu Gerceker Turk, Tugrul Dereli","doi":"10.5826/dpc.1502a4883","DOIUrl":"10.5826/dpc.1502a4883","url":null,"abstract":"<p><strong>Introduction: </strong>Matricectomy is an effective treatment method for ingrown toenails.</p><p><strong>Objectives: </strong>This study aimed to evaluate the outcomes of matricectomy procedures for ingrown toenails at a dermatology clinic, focusing on patient characteristics, recurrence rates, post-operative complications, and patient satisfaction.</p><p><strong>Methods: </strong>Patient records from 2009 to 2023 for those undergoing surgical or chemical matricectomy for ingrown toenails in the dermatological surgery unit were retrospectively reviewed.</p><p><strong>Results: </strong>The study analyzed 300 matricectomies performed on 164 patients. Chemical matricectomy was performed on 97.6% (160 patients), while 2.4% (4 patients) underwent surgical matricectomy alone, and 20.7% (34 patients) received both surgical and chemical matricectomy. Healing times and prolonged pain showed no significant differences between surgical, sodium hydroxide, and phenol matricectomy. No significant relationship was identified between side effect development and factors such as diabetes mellitus, previous nail procedures, or the type of matricectomy (surgical, phenol, or sodium hydroxide). Recurrence rates ranked from lowest to highest as follows: combined surgical and chemical, sodium hydroxide, and phenol matricectomy; however, these differences were not statistically significant.</p><p><strong>Conclusions: </strong>No significant difference was observed in recurrence rates, side effects, or patient satisfaction between surgical, sodium hydroxide, and phenol matricectomy procedures.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphological Evaluation of Facial Pigmented Lesions with Line-Field Confocal Optical Coherence Tomography: Correlation with Reflectance Confocal Microscopy. A Pilot Study.","authors":"Clément Lenoir, Mariano Suppa, Simone Soglia, Susana Puig, Linda Tognetti, Elisa Cinotti, Carmen Orte Cano, Gwendoline Diet, Pietro Rubegni, Jean-Luc Perrot, Véronique Del Marmol, Josep Malvehy, Javiera Perez-Anker","doi":"10.5826/dpc.1502a5068","DOIUrl":"10.5826/dpc.1502a5068","url":null,"abstract":"<p><strong>Introduction: </strong>Facial pigmented lesions pose significant challenges for diagnosis and treatment planning due to their anatomical topography and complexity. Traditional methods like dermoscopy have limitations, and while reflectance confocal microscopy (RCM) offers in-vivo cellular resolution, it is hindered by shallow penetration. The recently developed line-field confocal optical coherence tomography (LC-OCT) combines the benefits of OCT and RCM, providing deeper penetration and three-dimensional cellular imaging.</p><p><strong>Objectives: </strong>This study aims to assess the ability of LC-OCT in displaying morphological features correlated and compared with RCM and histopathological findings.</p><p><strong>Methods: </strong>Over a period of 1-year, various pigmented facial lesions were selected, including solar lentigo, seborrheic keratosis, lichen planus-like keratosis, pigmented actinic keratosis, basal cell carcinoma, compound nevus, lentigo maligna, and invasive melanoma. LC-OCT and RCM were used for imaging, and their morphological features were compared. Lesions, except solar lentigo and compound nevus, were excised for histopathological evaluation. Morphological criteria from imaging were correlated with histopathological findings.</p><p><strong>Results: </strong>LC-OCT matched RCM in spatial resolution while providing deeper tissue penetration and three-dimensional visualization. This advantage was particularly notable in pigmented actinic keratosis and basal cell carcinoma, where LC-OCT's vertical imaging offered unique diagnostic insights. It also enhanced the understanding of the architecture of melanocytic lesions.</p><p><strong>Conclusion: </strong>LC-OCT adds new insight into the imaging and diagnosis of facial pigmented lesions, offering additional morphological features. This pilot study highlights its potential to improve diagnostic accuracy and patient care, with further research needed to assess its broader clinical applications.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 2","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}