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Dermatology practical & conceptual最新文献

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Factors Influencing Relapse After Omalizumab in Chronic Urticaria. Does the Method of Discontinuation Influence Relapse? 影响慢性荨麻疹患者奥玛单抗治疗后复发的因素。停药的方法会影响复发吗？
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5196
Petek Üstün, Esra Adışen
{"title":"Factors Influencing Relapse After Omalizumab in Chronic Urticaria. Does the Method of Discontinuation Influence Relapse?","authors":"Petek Üstün, Esra Adışen","doi":"10.5826/dpc.1503a5196","DOIUrl":"10.5826/dpc.1503a5196","url":null,"abstract":"<p><strong>Introduction: </strong>Omalizumab is recommended for chronic urticaria (CU) until spontaneous remission occurs rather than for a specific period of time. The rate of relapse after treatment varies depending on the method of discontinuation.</p><p><strong>Objectives: </strong>Our study aimed to investigate how the method of omalizumab discontinuation and other factors affect the rate of post-treatment relapses.</p><p><strong>Methods: </strong>Patients with CU were divided into three groups based on their method of discontinuing omalizumab treatment: direct discontinuation, extending treatment intervals to eight weeks, and reducing the treatment dose to 150 mg/4 weeks. These groups were then compared for relapse rates.</p><p><strong>Results: </strong>A total of 200 patients were included in this study. Among the 109 patients who discontinued omalizumab directly, 65.1% experienced a relapse. The relapse rate was 40.7% in those who extended the treatment intervals to eight weeks and 15.6% in those who reduced the dose to 150 mg/4 weeks. There was a statistically significant difference in post-treatment relapse rates according to the method of discontinuation (P< 0.001).</p><p><strong>Conclusions: </strong>Gradual tapering of treatment rather than direct discontinuation has been shown to prolong remission. Achieving the lowest relapse rate with a reduction in the treatment dose to 150 mg/4 weeks is significant for the design of omalizumab discontinuation protocol and provides insights for future studies.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laser Therapy Approaches in the Treatment of Kaposi's Sarcoma: A Comprehensive Review of Dermatologic Options. 激光治疗卡波西肉瘤的方法：皮肤科选择的综合综述。
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5332
Chiara Battilotti, Fortunato Cassalia, Francesca Svara, Alessandra Latini, Norma Cameli, Steven Paul Nisticò
{"title":"Laser Therapy Approaches in the Treatment of Kaposi's Sarcoma: A Comprehensive Review of Dermatologic Options.","authors":"Chiara Battilotti, Fortunato Cassalia, Francesca Svara, Alessandra Latini, Norma Cameli, Steven Paul Nisticò","doi":"10.5826/dpc.1503a5332","DOIUrl":"10.5826/dpc.1503a5332","url":null,"abstract":"<p><strong>Introduction: </strong>Kaposi's sarcoma (KS) is a multicentric angioproliferative disease associated with human herpesvirus 8 and often exacerbated by immunosuppression. Effective treatment includes systemic and local therapies, with laser treatments gaining prominence in dermatological practice.</p><p><strong>Objectives: </strong>This narrative review evaluated the efficacy and safety of laser treatment modalities in the management of cutaneous and mucosal KS lesions to guide dermatological decision-making.</p><p><strong>Methods: </strong>A comprehensive English-language literature search was conducted using PubMed and Scopus up to November 2024. Search terms included \"Kaposi's sarcoma\", \"laser therapy,\" and \"laser treatment.\" Case reports and observational studies with defined patient characteristics, standardized laser protocols, and documented outcomes were included.</p><p><strong>Results: </strong>The Nd:YAG laser emerged as the leading modality for thick, nodular KS lesions, demonstrating deep tissue penetration and high efficacy with minimal adverse effects. The pulsed dye laser (PDL) was highly effective for superficial cutaneous and mucosal lesions, with excellent cosmetic outcomes and minimal recurrence. The CO<sub>2</sub> laser showed promise in ablating small lesions but had limitations due to scarring risks and potential biohazard concerns. Argon lasers were historically important but are now less favored due to lower specificity for vascular targets and higher risk of non-vascular tissue damage.</p><p><strong>Conclusions: </strong>Laser therapy offers versatile and effective treatment options for KS. Nd:YAG and PDL lasers are particularly promising due to their high efficacy, favorable safety profiles, and low recurrence rates. Further research is needed to refine laser protocols and validate long-term outcomes in different patient populations.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging Pemphigoid Gestationis and Parry Romberg Syndrome: New Perspectives on Autoimmune Disorder Interactions. 桥接类天疱疮妊娠和Parry Romberg综合征：自身免疫性疾病相互作用的新观点。
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5619
Guneet Awal, Navleen Kaur, Amandeep Singh, Arora Pooja
{"title":"Bridging Pemphigoid Gestationis and Parry Romberg Syndrome: New Perspectives on Autoimmune Disorder Interactions.","authors":"Guneet Awal, Navleen Kaur, Amandeep Singh, Arora Pooja","doi":"10.5826/dpc.1503a5619","DOIUrl":"10.5826/dpc.1503a5619","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reflectance Confocal Microscopy and LC-OCT for Noninvasive Evaluation of Clonal Seborrheic Keratosis in Dark Skin Individuals. 反射共聚焦显微镜和LC-OCT在黑皮肤个体克隆性脂溢性角化病中的无创评价。
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5961
Giulio Cortonesi, Vittoria Cioppa, Linda Tognetti, Pietro Rubegni, Elisa Cinotti
{"title":"Reflectance Confocal Microscopy and LC-OCT for Noninvasive Evaluation of Clonal Seborrheic Keratosis in Dark Skin Individuals.","authors":"Giulio Cortonesi, Vittoria Cioppa, Linda Tognetti, Pietro Rubegni, Elisa Cinotti","doi":"10.5826/dpc.1503a5961","DOIUrl":"10.5826/dpc.1503a5961","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous Angiosarcoma Mimics Basal Cell Carcinoma: Utility of Optical Super-High Magnification Dermoscopy in Differential Diagnosis. 皮肤血管肉瘤模拟基底细胞癌：光学超高倍皮肤镜在鉴别诊断中的应用。
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5296
Stefania Guida, Gianmarco Diego Bigotto, Giorgio Stabile, Antonio Podo Brunetti, Nathalie Rizzo, Franco Rongioletti
{"title":"Cutaneous Angiosarcoma Mimics Basal Cell Carcinoma: Utility of Optical Super-High Magnification Dermoscopy in Differential Diagnosis.","authors":"Stefania Guida, Gianmarco Diego Bigotto, Giorgio Stabile, Antonio Podo Brunetti, Nathalie Rizzo, Franco Rongioletti","doi":"10.5826/dpc.1503a5296","DOIUrl":"10.5826/dpc.1503a5296","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing Diagnosis of Flat Pigmented Basal Cell Carcinoma with Line-Field Confocal Optical Coherence Tomography. 线场共聚焦光学相干断层扫描增强扁平型基底细胞癌的诊断价值。
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5344
Antonio Di Guardo, Luca Ambrosio, Giovanni Di Lella, Giovanni Pellacani, Claudio Conforti
{"title":"Enhancing Diagnosis of Flat Pigmented Basal Cell Carcinoma with Line-Field Confocal Optical Coherence Tomography.","authors":"Antonio Di Guardo, Luca Ambrosio, Giovanni Di Lella, Giovanni Pellacani, Claudio Conforti","doi":"10.5826/dpc.1503a5344","DOIUrl":"10.5826/dpc.1503a5344","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eruptive Disseminated Spitz Nevi With Architectural Features of Clark/Dysplastic Nevus. 爆发性弥散性斯皮茨痣伴克拉克/发育不良痣的建筑特征。
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5323
Giovanna Curi Campos, Elizabeth Leocadia Fernandes, Jan Lapins, Karina Schultz, Ricardo Silvestre Silva Macarenco, Mariana Tavares Colferai
{"title":"Eruptive Disseminated Spitz Nevi With Architectural Features of Clark/Dysplastic Nevus.","authors":"Giovanna Curi Campos, Elizabeth Leocadia Fernandes, Jan Lapins, Karina Schultz, Ricardo Silvestre Silva Macarenco, Mariana Tavares Colferai","doi":"10.5826/dpc.1503a5323","DOIUrl":"10.5826/dpc.1503a5323","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flagellate Rash in Chikungunya: A Comprehensive Review of Dermatological Manifestations. 基孔肯雅热鞭毛疹：皮肤病表现的综合综述。
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5363
Nikhil Mehta, Sonali Gupta, K M Sathvi, Neetu Bhari
{"title":"Flagellate Rash in Chikungunya: A Comprehensive Review of Dermatological Manifestations.","authors":"Nikhil Mehta, Sonali Gupta, K M Sathvi, Neetu Bhari","doi":"10.5826/dpc.1503a5363","DOIUrl":"10.5826/dpc.1503a5363","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multicentric Granular Cell Tumor With Uncommon Dermoscopic Features. 具有罕见皮肤镜特征的多中心颗粒细胞瘤。
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5433
Inês Aparício Martins, Alexandre João, Juliana Baptista, Cândida Fernandes
{"title":"Multicentric Granular Cell Tumor With Uncommon Dermoscopic Features.","authors":"Inês Aparício Martins, Alexandre João, Juliana Baptista, Cândida Fernandes","doi":"10.5826/dpc.1503a5433","DOIUrl":"10.5826/dpc.1503a5433","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Case of Compound Spitz Nevus with Somatotropin Treatment: Rare Clinical Findings and Diagnostic Approach. 生长激素治疗小儿复合斯皮茨痣：罕见的临床表现和诊断方法。
IF 2.3 4区 医学
Dermatology practical & conceptual Pub Date : 2025-07-31 DOI: 10.5826/dpc.1503a5464
Amanda do Carmo Gusmão, Ana Clara Braga, Gabriela Dal Bosco Guarda, Carlos Arthur de Figueiredo Athayde, Luciana Pantaleão, Juliane Lucio Coutinho Dos Santos
{"title":"Pediatric Case of Compound Spitz Nevus with Somatotropin Treatment: Rare Clinical Findings and Diagnostic Approach.","authors":"Amanda do Carmo Gusmão, Ana Clara Braga, Gabriela Dal Bosco Guarda, Carlos Arthur de Figueiredo Athayde, Luciana Pantaleão, Juliane Lucio Coutinho Dos Santos","doi":"10.5826/dpc.1503a5464","DOIUrl":"10.5826/dpc.1503a5464","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"15 3","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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