Tullio Brunetti, Marco Adriano Chessa, Annalucia Virdi, Iria Neri
{"title":"Rare Case of Cellular Neurothekeoma in an Infant with an Asymptomatic Abdominal Nodule.","authors":"Tullio Brunetti, Marco Adriano Chessa, Annalucia Virdi, Iria Neri","doi":"10.5826/dpc.1403a199","DOIUrl":"10.5826/dpc.1403a199","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 3","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11313544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tugba Atak, Selda Pelin Kartal, Elif Bengu Gungor, Fatma Ucar
{"title":"Serum Calprotectin Levels in Vitiligo Patients and Disease Relation.","authors":"Tugba Atak, Selda Pelin Kartal, Elif Bengu Gungor, Fatma Ucar","doi":"10.5826/dpc.1403a184","DOIUrl":"10.5826/dpc.1403a184","url":null,"abstract":"<p><strong>Introduction: </strong>Vitiligo is characterized as melanocyte loss in skin and mucous membranes, the pathogenesis of which has not yet been clarified. Calprotectin is a protein secreted from neutrophils, monocytes, and dendritic cells which has an effect on cytokine receptor regulation and the production of reactive oxygen radicals. It has been the subject of research in various inflammatory and autoimmune diseases, yet not investigated in vitiligo.</p><p><strong>Objective: </strong>The aim of our study was to investigate the role of calprotectin in the etiopathogenesis of vitiligo and its relationship with clinical subtypes and disease scores.</p><p><strong>Methods: </strong>Forty-four vitiligo patients with lack of autoimmune disease and 36 age- and sex-matched healthy controls were involved in the study. Serum calprotectin levels were measured by ELISA. The results were compared with the control group, and the relationship between patients' demographic characteristics, skin phototypes, disease type, disease scores (Vitiligo Area Scoring Index and Vitiligo Disease Activity Score), disease duration, and age at onset were evaluated.</p><p><strong>Results: </strong>The median serum calprotectin level was 454.08 pg/ml (41.19-873.41) in the patient group, and the median serum calprotectin level was 223.17 pg/ml (44.88-1044.43) in the control group. Serum calprotectin level was significantly higher in the patient group than in the control group (P = 0.016). No correlation was found between serum calprotectin level and disease scores, disease duration, age, or age of onset of disease (P > 0.05).</p><p><strong>Conclusions: </strong>In our study, serum calprotectin levels in the patient group were found to be significantly higher than in the control group. Our findings and the existing literature on calprotectin suggest its potential involvement in the pathogenesis of vitiligo, independent of disease progression and patient characteristics.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 3","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11314025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Case of Young Patient With Keloid After Topical Treatment with Potassium Hydroxide 5% of Molluscum Contagiosum.","authors":"Federico Bardazzi, Tullio Brunetti, Cosimo Misciali, Giacomo Clarizio, Camilla Loi, Alessandro Pileri","doi":"10.5826/dpc.1403a189","DOIUrl":"10.5826/dpc.1403a189","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 3","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11314405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iria Neri, Gionathan Orioni, Miriam Leuzzi, Elena Facchini, Elena Mengozzi, Marco Adriano Chessa
{"title":"Infantile Hemangioma with Minimal or Arrested Growth (IHMAG): A Retrospective Analysis of Clinical and Dermoscopic Diagnostic Clues.","authors":"Iria Neri, Gionathan Orioni, Miriam Leuzzi, Elena Facchini, Elena Mengozzi, Marco Adriano Chessa","doi":"10.5826/dpc.1403a206","DOIUrl":"10.5826/dpc.1403a206","url":null,"abstract":"<p><strong>Introduction: </strong>Infantile hemangioma with minimal or arrested growth (IHMAG) is an unusual subset of infantile hemangioma, difficult to recognize because they are often mistaken for capillary malformation or other entities. Dermoscopic features of IHMAG have been described only in small case series so far.</p><p><strong>Objectives: </strong>The aim of our study was to evaluate epidemiological, clinical, and dermoscopic features in 79 cases of IHMAG with a specific focus on neonates and toddlers with segmental complicated IHMAG and to provide a remarkable dermoscopic criterion to achieve diagnosis.</p><p><strong>Methods: </strong>This case series collected all the cases of IHMAG recorded in our Clinical Registry from January 2012 to March 2022.</p><p><strong>Results: </strong>A total of 79 cases of IHMAG were identified in our study; 53 (67.1%) were localized and 26 (32.9 %) were segmental. Patients showed some complications during follow-up such as ulceration and soft tissue anomalies. One PHACE syndrome and two LUMBAR syndromes were included. Our study highlights the main dermoscopic features differentiating IHMAG from infantile hemangiomas and capillary malformations in neonatal patients, highlighting the presence of enlarged unfocused telangiectatic vessels as remarkable clues.</p><p><strong>Conclusions: </strong>This is a large case series described in the literature about this rare entity. We emphasize that segmental IHMAG may be associated with structural abnormalities and may pose a diagnostic challenge especially in its rare facial segmental localization. The use of dermoscopy allowed us to find typical signs for IHMAG, thus avoiding the execution of invasive methods and ensuring the prompt suspicion of a syndrome in segmental neonatal cases.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 3","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11313902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preventing Delays in Care For Racial Minorities: Examining Referral Patterns in a Nail Specialty Clinic.","authors":"Rachel C Hill, Rhiannon C Miller, Shari R Lipner","doi":"10.5826/dpc.1403a192","DOIUrl":"10.5826/dpc.1403a192","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 3","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11314152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aurora Maria Alessandrini, Alice Nadia Rossi, Emi Dika
{"title":"Folliculitis Decalvans Due to Epidermal Growth Factor Inhibitor.","authors":"Aurora Maria Alessandrini, Alice Nadia Rossi, Emi Dika","doi":"10.5826/dpc.1403a161","DOIUrl":"10.5826/dpc.1403a161","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"14 3","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11314079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}