Lana Salloum, Eliza Dewey, Ursula Biba, Rachel Day, Arash Mostaghimi
{"title":"Clinical Outcomes in a Longitudinal Virtual Dermatology Care Model for Eczema and Psoriasis.","authors":"Lana Salloum, Eliza Dewey, Ursula Biba, Rachel Day, Arash Mostaghimi","doi":"10.5826/dpc.1603a7607","DOIUrl":"10.5826/dpc.1603a7607","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Less Is More: Cost-Effective Psoriasis Management via Disease-Driven Dosing of IL-17/IL-23 Inhibitors.","authors":"Edoardo Cammarata, Chiara Airoldi, Jacopo Colombo, Andrealuna Ucciero, Luca Mastorino, Veronica Arese, Lorenza Burzi, Franco Castelli, Massimo Chiarpenello, Francesca Graziola, Claudia Leporati, Michela Ortoncelli, Paolo Pella, Ginevra Pertusi, Alessia Pisterna, Pietro Quaglino, Simone Ribero, Gianluca Rossotto, Rossana Tiberio, Paolo Dapavo, Paola Savoia","doi":"10.5826/dpc.1603a6747","DOIUrl":"10.5826/dpc.1603a6747","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic plaque psoriasis is commonly treated with IL-17 and IL-23 inhibitors, which are highly effective but associated with substantial costs. Because many patients achieve long-term disease control, fixed-dose regimens may result in overtreatment.</p><p><strong>Objectives: </strong>This study assessed the economic impact of disease-activity-guided dose reduction (DR) strategies using secukinumab, brodalumab, guselkumab, and risankizumab in adults with stable plaque psoriasis.</p><p><strong>Methods: </strong>This cost analysis was based on data from the PSORED trial, a multicenter prospective open-label study conducted in Piedmont, Italy (2023-2025). Patients with stable disease (PASI ≤3, DLQI ≤3 for ≥9 months) underwent DR trough a 1.5x extension of maintenance dosing intervals. Costs under DR and standard dosing (SD) were compared over 52 weeks using Italian tariff data and real-world treatment patterns.</p><p><strong>Results: </strong>Among 156 enrolled patients, 39 discontinued DR, 38 returned to standard dosing, and one switched therapy. DR reduced biologics consumption without increasing follow-up requirements, yielding a 26% decrease in total costs and an average annual saving of €7,303.57 per patient.</p><p><strong>Conclusions: </strong>DR was both clinically effective and cost-saving, maintaining disease control without major safety concerns. These findings support the implementation of DR strategies in routine clinical practice to enhance long-term sustainability while preserving therapeutic efficacy.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Cleiman, Ayal Hassidim, Rony Shreberk-Hassidim
{"title":"National Crisis-Induced Psychological Stress and Increased Herpes Zoster Incidence: A 10-Year Retrospective Study.","authors":"Michael Cleiman, Ayal Hassidim, Rony Shreberk-Hassidim","doi":"10.5826/dpc.1603a6852","DOIUrl":"10.5826/dpc.1603a6852","url":null,"abstract":"<p><strong>Introduction: </strong>Psychological stress is known to affect dermatological conditions, but its impact during national crises is not well established.</p><p><strong>Objectives: </strong>To assess the association between crisis-induced stress and the incidence of infectious and inflammatory skin diseases, focusing on herpes zoster.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was performed using emergency room records from Hadassah Medical Center, Israel. Skin-related visits were compared between October and December 2023 (national crisis), and the same months in 2014-2022: between the COVID-19 lockdowns (March-May 2020, December 2020-February 2021) and pre-pandemic years (2014-2022). Logistic regression models, adjusted for age and sex, evaluated disease incidence.</p><p><strong>Results: </strong>Among 1,644 patients, infectious skin diseases increased significantly during the October-December 2023 crisis (odds ratio (OR)=2.106; P<0.001), mainly due to herpes zoster (OR=2.616; P=0.009). No significant change was observed for inflammatory skin diseases. During COVID-19 lockdowns, no significant difference was found, likely reflecting reduced healthcare utilization.</p><p><strong>Conclusions: </strong>National crisis-related stress was associated with higher incidence of infectious skin diseases, particularly herpes zoster, but not with inflammatory conditions. These findings support targeted interventions, including vaccination and stress management, during crises.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric and Elderly Teledermatology in a Rural Area of Spain: A Descriptive Study.","authors":"Gloria Baeza-Hernández, Freddy Eduardo Rojas-Farias, Carolina Sanz-Muñoz, Beatriz Casado-Verrier","doi":"10.5826/dpc.1603a6550","DOIUrl":"10.5826/dpc.1603a6550","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesca Pampaloni, Stephano Cedirian, Daniel Fernandez Melo, Aurora Maria Alessandrini, Alessandro Pileri, Bianca Maria Piraccini, Michela Starace
{"title":"Trichoscopy of Scalp Folliculotropic Mycosis Fungoides: A Review of the Literature.","authors":"Francesca Pampaloni, Stephano Cedirian, Daniel Fernandez Melo, Aurora Maria Alessandrini, Alessandro Pileri, Bianca Maria Piraccini, Michela Starace","doi":"10.5826/dpc.1603a6459","DOIUrl":"10.5826/dpc.1603a6459","url":null,"abstract":"<p><strong>Background: </strong>Mycosis fungoides (MF) is the most common type of T-cell lymphoma and is characterized by the infiltration of the epidermis by small to medium-sized atypical T lymphocytes. Folliculotropic MF (FMF) is a rare clinicopathological variant of MF characterized by preferential infiltration of the follicular epithelium. Clinical presentation of FMF can vary from follicle-based patches to plaques, nodules, and tumors, with cicatricial or not alopecia. The most involved site is the head, especially the face.</p><p><strong>Objective: </strong>The aim of this review was to assess the main trichoscopic findings reported in scalp lesions.</p><p><strong>Methods: </strong>A comprehensive literature search of PubMed was performed.</p><p><strong>Results: </strong>Ten studies were included; the trichoscopic features reported were decreased number of pilosebaceous units, dotted dilated vessels, white/yellow scales, and perifollicular halos. The main clinical presentation reported were patchy alopecia or generalized alopecia. Most of the studies included were case reports, so studies with larger sample sizes are strongly needed to make trichoscopy a complementary diagnostic tool to improve the differential diagnoses between FMF and other scalp disorders.</p><p><strong>Conclusion: </strong>Trichoscopy plays a key role in diagnosing FMF of the scalp, revealing characteristic features such as milky-red globules, orange-yellow patches, comedones, and distinct vascular patterns.</p>","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vincenzina Rubino, Elisa Margherita Difonzo, Luigi Pisano
{"title":"Dermatophytic Infections of the Eyebrows Due To Nannizzia Gypsea: A Case Series.","authors":"Vincenzina Rubino, Elisa Margherita Difonzo, Luigi Pisano","doi":"10.5826/dpc.1603a7226","DOIUrl":"10.5826/dpc.1603a7226","url":null,"abstract":"","PeriodicalId":11168,"journal":{"name":"Dermatology practical & conceptual","volume":"16 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}