Developmental psychobiology最新文献_第5页

Chloride Modulates Central pH Sensitivity and Plasticity of Brainstem Breathing-Related Biorhythms in Zebra Finch Embryos 氯化物调节斑马雀胚胎中枢 pH 值敏感性和脑干呼吸相关生物节律的可塑性

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-06-25 DOI: 10.1002/dev.22518

Jessica R. Whitaker-Fornek, Jennie K. Nelson, Jason Q. Pilarski

{"title":"Chloride Modulates Central pH Sensitivity and Plasticity of Brainstem Breathing-Related Biorhythms in Zebra Finch Embryos","authors":"Jessica R. Whitaker-Fornek, Jennie K. Nelson, Jason Q. Pilarski","doi":"10.1002/dev.22518","DOIUrl":"10.1002/dev.22518","url":null,"abstract":"<div>\u0000 \u0000 All terrestrial vertebrate life must transition from aquatic gas exchange in the embryonic environment to aerial or pulmonary respiration at birth. In addition to being able to breathe air, neonates must possess functional sensory feedback systems for maintaining acid–base balance. Respiratory neurons in the brainstem act as pH sensors that can adjust breathing to regulate systemic pH. The central pH sensitivity of breathing-related motor output develops over the embryonic period in the zebra finch (Taeniopygia guttata). Due to the key role of chloride ions in electrochemical stability and developmental plasticity, we tested chloride's role in the development of central pH sensitivity. We blocked gamma-aminobutyric acid-A receptors and cation-chloride cotransport that subtly modulated the low-pH effects on early breathing biorhythms. Further, chloride-free artificial cerebrospinal fluid altered the pattern and timing of breathing biorhythms and blocked the stimulating effect of acidosis in E12–14 brainstems. Early and middle stage embryos exhibited rebound plasticity in brainstem motor outputs during low-pH treatment, which was eliminated by chloride-free solution. Results show that chloride modulates low-pH sensitivity and rebound plasticity in the zebra finch embryonic brainstem, but work is needed to determine the cellular and circuit mechanisms that control functional chloride balance during acid–base disturbances.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141455791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early Life Surgency, but not Effortful Control or Negative Affectivity, Is a Mediating Variable Between Maternal Pre-Pregnancy Body Mass Index and Childhood Obesity Risk 母亲孕前体重指数与儿童肥胖风险之间的中介变量是早期生活中的骚动，而不是努力控制或负性情感。

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-06-25 DOI: 10.1002/dev.22517

Nicole A. Cho, Gerald F. Giesbrecht, Deborah Dewey, Raylene A. Reimer

{"title":"Early Life Surgency, but not Effortful Control or Negative Affectivity, Is a Mediating Variable Between Maternal Pre-Pregnancy Body Mass Index and Childhood Obesity Risk","authors":"Nicole A. Cho, Gerald F. Giesbrecht, Deborah Dewey, Raylene A. Reimer","doi":"10.1002/dev.22517","DOIUrl":"10.1002/dev.22517","url":null,"abstract":"Maternal gestational obesity is related to risk of obesity in the child. This risk may be in part mediated by altered child temperament, which can affect mother–child interactions, including feeding and soothing behaviors that affect obesity risk. Our objective was to examine the association between maternal pre-pregnancy BMI and child zBMI and determine if child temperament, specifically positive Affectivity/Surgency, mediates this association. Using conditional process modeling, we analyzed data from 408 mother–child dyads enrolled in the Alberta Pregnancy Outcomes and Nutrition (APrON) study. Child temperament was assessed at 3 years of age via a parent report measure, the Child Behavior Questionnaire (CBQ), and child zBMI was calculated from in-person measurements of child height and weight at 4–5 years of age. Bivariate correlations showed that there was a significant positive correlation between zBMI and Surgency (r = 0.11, p = 0.03), and zBMI was also correlated with maternal pre-pregnancy BMI (r = 0.12, p = 0.02). Multivariable regression revealed that maternal pre-pregnancy BMI (adjusted β = 0.15, 95% confidence interval [CI]; 0.00–0.05, p = 0.02) and Surgency scores (adjusted β = 0.14, 95% CI; 0.02–0.28, p = 0.03) were associated with higher child zBMI at 4–5 years of age. Mediation analysis showed that Surgency mediated the association between pre-pregnancy BMI and child zBMI. Our models controlled for maternal gestational weight gain, gestational diabetes, socioeconomic status, maternal anxiety and depression, and gestational age at birth. Overall, maternal pre-pregnancy BMI was positively associated with child zBMI, and this association was mediated by higher child Surgency scores.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22517","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141455792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural Sensitivity to Peer Feedback and Depressive Symptoms: Moderation by Executive Function 对同伴反馈的神经敏感性与抑郁症状：执行功能的调节作用

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-06-25 DOI: 10.1002/dev.22515

Megan M. Davis, Haina H. Modi, Haley V. Skymba, Katherine Haigler, Megan K. Finnegan, Eva H. Telzer, Karen D. Rudolph

引用次数: 0

From One's Heart to the Mind of Others: A Study in School-Aged Children 从自己的心灵到他人的心灵：学龄儿童研究

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-06-25 DOI: 10.1002/dev.22516

Marta Zammuto, Cristina Ottaviani, Dora Bianchi, Fiorenzo Laghi, Antonia Lonigro

引用次数: 0

Parental Exposure to Morphine Before Conception Decreases Morphine and Cocaine-Induced Locomotor Sensitization in Male Offspring 父母在受孕前接触吗啡会降低男性后代对吗啡和可卡因诱导的运动敏感性

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-06-24 DOI: 10.1002/dev.22514

Amirhossein Heidari, Arman Hajikarim-Hamedani, Saereh Hosseindoost, Yekta Ghane, Mitra Sadat-Shirazi, Mohammad-Reza Zarrindast

{"title":"Parental Exposure to Morphine Before Conception Decreases Morphine and Cocaine-Induced Locomotor Sensitization in Male Offspring","authors":"Amirhossein Heidari, Arman Hajikarim-Hamedani, Saereh Hosseindoost, Yekta Ghane, Mitra Sadat-Shirazi, Mohammad-Reza Zarrindast","doi":"10.1002/dev.22514","DOIUrl":"10.1002/dev.22514","url":null,"abstract":"<div>\u0000 \u0000 Repeated exposure to abused drugs leads to reorganizing synaptic connections in the brain, playing a pivotal role in the relapse process. Additionally, recent research has highlighted the impact of parental drug exposure before gestation on subsequent generations. This study aimed to explore the influence of parental morphine exposure 10 days prior to pregnancy on drug-induced locomotor sensitization. Adult male and female Wistar rats were categorized into morphine-exposed and control groups. Ten days after their last treatment, they were mated, and their male offspring underwent morphine, methamphetamine, cocaine, and nicotine-induced locomotor sensitization tests. The results indicated increased locomotor activity in both groups after drug exposure, although the changes were attenuated in morphine and cocaine sensitization among the offspring of morphine-exposed parents (MEPs). Western blotting analysis revealed altered levels of D2 dopamine receptors (D2DRs) in the prefrontal cortex and nucleus accumbens of the offspring from MEPs. Remarkably, despite not having direct in utero drug exposure, these offspring exhibited molecular alterations affecting morphine and cocaine-induced sensitization. The diminished sensitization to morphine and cocaine suggested the development of a tolerance phenotype in these offspring. The changes in D2DR levels in the brain might play a role in these adaptations.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141455807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contributions of dysfunctional plasticity mechanisms to the development of atypical perceptual processing 功能失调的可塑性机制对非典型知觉加工发展的贡献

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2024-06-04 DOI: 10.1002/dev.22504

Stacy Moppert, Eduardo Mercado III

引用次数: 0

RSA instability in mothers of preschoolers and adolescents is related to observations of supportive parenting behaviors 学龄前儿童和青少年母亲的 RSA 不稳定性与观察到的支持性养育行为有关

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2024-06-04 DOI: 10.1002/dev.22513

Molly E. Hale, Kayley E. Morrow, Jianjie Xu, Zhuo Rachel Han, Assaf Oshri, Anne Shaffer, Margaret O. Caughy, Cynthia Suveg

{"title":"RSA instability in mothers of preschoolers and adolescents is related to observations of supportive parenting behaviors","authors":"Molly E. Hale, Kayley E. Morrow, Jianjie Xu, Zhuo Rachel Han, Assaf Oshri, Anne Shaffer, Margaret O. Caughy, Cynthia Suveg","doi":"10.1002/dev.22513","DOIUrl":"https://doi.org/10.1002/dev.22513","url":null,"abstract":"Respiratory sinus arrhythmia (RSA; a measure of respiratory modulation of vagal control of heart rate) is a dynamic process. For mothers, RSA functioning has been associated with depressive symptoms and coincides with supportive parenting. However, research has largely focused on RSA suppression (i.e., difference score from rest to stress task). The present study examined depressive symptoms and supportive parenting with RSA instability—a dynamic measure of the magnitude of RSA change across a task. In two samples of mothers (N = 210), one with preschoolers (Study 1: n = 108, Mage = 30.68 years, SD = 6.06, 47.0% Black, 43.0% White) and one with adolescents (Study 2: n = 102, Mage = 35.51, SD = 6.51, 75.2% Black), RSA instability was calculated during an interaction task. In both studies, instrumental supportive parenting behaviors were negatively related to RSA instability. Findings provide preliminary support for RSA instability as an indicator of physiological dysregulation for mothers.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22513","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141251283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations between adversity in the family of origin and hair cortisol concentration in adulthood 原生家庭的逆境与成年后毛发皮质醇浓度之间的关系

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2024-06-04 DOI: 10.1002/dev.22512

Tricia K. Neppl, Olivia N. Diggs, Brenda J. Lohman, Jeenkyoung Lee, Daniel Russell, Anne M. Bronikowski

{"title":"Associations between adversity in the family of origin and hair cortisol concentration in adulthood","authors":"Tricia K. Neppl, Olivia N. Diggs, Brenda J. Lohman, Jeenkyoung Lee, Daniel Russell, Anne M. Bronikowski","doi":"10.1002/dev.22512","DOIUrl":"https://doi.org/10.1002/dev.22512","url":null,"abstract":"The current study examined associations between parental adversities as experienced in adolescence and hair cortisol concentration (HCC) 26 years later (n = 47). Specifically, bivariate correlations and linear regressions were used to examine harsh parenting as well as parental economic pressure, emotional distress, and body mass index (BMI) when their adolescent was between 15 and 16 years old (parent average age 43). HCC was measured when the adolescent was an adult (average 42 years old), at a similar age to when their parent(s) first participated in the study. We also assessed their economic pressure, emotional distress, obesity, and perceived stress in adulthood. For results across generations, parental economic pressure experienced during adolescence was significantly related to HCC when these adolescents were adults. None of the adult economic pressure, emotional distress, BMI, and perceived stress variables were associated with their HCC. Interestingly, there were significant associations among adult perceived stress, economic pressure, emotional distress, and obesity. Thus, the association between parental economic pressure and adult HCC is independent of adult adversities. Results highlight early economic adversity as a possible childhood stressor that has implications throughout the life course.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22512","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141251282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex differences in acute early life stress-enhanced fear learning in adult rats 成年大鼠早期急性应激增强恐惧学习的性别差异

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2024-06-04 DOI: 10.1002/dev.22511

Brianna L. Minshall, Rachel A. Skipper, Collin A. Riddle, Catherine F. Wasylyshyn, Dragana I. Claflin, Jennifer J. Quinn

{"title":"Sex differences in acute early life stress-enhanced fear learning in adult rats","authors":"Brianna L. Minshall, Rachel A. Skipper, Collin A. Riddle, Catherine F. Wasylyshyn, Dragana I. Claflin, Jennifer J. Quinn","doi":"10.1002/dev.22511","DOIUrl":"https://doi.org/10.1002/dev.22511","url":null,"abstract":"Patients diagnosed with posttraumatic stress disorder (PTSD) present with a spectrum of debilitating anxiety symptoms resulting from exposure to trauma. Women are twice as likely to be diagnosed with anxiety and PTSD compared to men; however, the reason for this vulnerability remains unknown. We conducted four experiments where we first demonstrated a female vulnerability to stress-enhanced fear learning (SEFL) with a moderate, acute early life stress (aELS) exposure (4 footshocks in a single session), compared to a more intense aELS exposure (15 footshocks in a single session) where males and females demonstrated comparable SEFL. Next, we demonstrated that this female vulnerability does not result from differences in footshock reactivity or contextual fear conditioning during the aELS exposure. Finally, using gonadectomy or sham surgeries in adult male and female rats, we showed that circulating levels of gonadal steroid hormones at the time of adult fear conditioning do not explain the female vulnerability to SEFL. Additional research is needed to determine whether this vulnerability can be explained by organizational effects of gonadal steroid hormones or differences in sex chromosome gene expression. Doing so is critical for a better understanding of increased female vulnerability to certain psychiatric diseases.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22511","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141251281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why do individuals with Williams syndrome or Down syndrome fail the Weather Prediction Task? 为什么威廉姆斯综合症或唐氏综合症患者无法完成天气预测任务？

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2024-05-28 DOI: 10.1002/dev.22503

Emilie Bochud-Fragnière, Gianni Lonchampt, Paola Bittolo, Giada Ehrensperger, Antonella Rita Circelli, Nicole Antonicelli, Floriana Costanzo, Deny Menghini, Stefano Vicari, Pamela Banta Lavenex, Pierre Lavenex

{"title":"Why do individuals with Williams syndrome or Down syndrome fail the Weather Prediction Task?","authors":"Emilie Bochud-Fragnière, Gianni Lonchampt, Paola Bittolo, Giada Ehrensperger, Antonella Rita Circelli, Nicole Antonicelli, Floriana Costanzo, Deny Menghini, Stefano Vicari, Pamela Banta Lavenex, Pierre Lavenex","doi":"10.1002/dev.22503","DOIUrl":"10.1002/dev.22503","url":null,"abstract":"Williams syndrome (WS) and Down syndrome (DS) are two neurodevelopmental disorders with distinct genetic origins characterized by mild to moderate intellectual disability. Individuals with WS or DS exhibit impaired hippocampus-dependent place learning and enhanced striatum-dependent spatial response learning. Here, we used the Weather Prediction Task (WPT), which can be solved using hippocampus- or striatum-dependent learning strategies, to determine whether individuals with WS or DS exhibit similar profiles outside the spatial domain. Only 10% of individuals with WS or DS solved the WPT. We further assessed whether a concurrent memory task could promote reliance on procedural learning to solve the WPT in individuals with WS but found that the concurrent task did not improve performance. To understand how the probabilistic cue–outcome associations influences WPT performance, and whether individuals with WS or DS can ignore distractors, we assessed performance using a visual learning task with differing reward contingencies, and a modified WPT with unpredictive cues. Both probabilistic feedback and distractors negatively impacted the performance of individuals with WS or DS. These findings are consistent with deficits in hippocampus-dependent learning and executive functions, and reveal the importance of congruent feedback and the minimization of distractors to optimize learning in these two populations.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22503","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0