Developmental psychobiology最新文献_第4页

Inflammatory Stress Response During Pregnancy as a Connecting Link in Intergenerational Risk Cascades 妊娠期间的炎症应激反应是代际风险级联的连接环节。

IF 1.9 4区心理学

Developmental psychobiology Pub Date : 2026-06-30 DOI: 10.1002/dev.70178

Heidemarie K. Laurent, Sherryl H. Goodman, Karen D. Rudolph, Kento Suzuki, Penina Backer, Aastha Dhimal, Sarah Pikhit, Douglas A. Granger

{"title":"Inflammatory Stress Response During Pregnancy as a Connecting Link in Intergenerational Risk Cascades","authors":"Heidemarie K. Laurent, Sherryl H. Goodman, Karen D. Rudolph, Kento Suzuki, Penina Backer, Aastha Dhimal, Sarah Pikhit, Douglas A. Granger","doi":"10.1002/dev.70178","DOIUrl":"10.1002/dev.70178","url":null,"abstract":"Pregnancy represents a critical juncture for intergenerational transmission of stress-related health vulnerabilities when child-bearers’ history of maltreatment may precipitate stress responses that adversely impact maternal and fetal outcomes. We aimed to shed light on this path by testing hypotheses that (1) childhood maltreatment would predict oral inflammatory responses to acute stress in late pregnancy, and (2) these inflammatory responses would relate to subsequent obstetric complications. Hypotheses were tested in a community sample of women (n = 158) from a larger longitudinal study. Participants reported a history of maltreatment and completed the Trier Social Stress Test during the third trimester of pregnancy. Five saliva samples collected before and after the task were assayed for pro-inflammatory cytokines (IL1β, IL6, TNFα) and C-reactive protein (CRP) to index oral inflammation. At 3 months postnatal, women reported pregnancy and birth complications, and birth outcomes. Multilevel models of inflammatory response trajectories supported hypothesized paths: Greater childhood maltreatment—especially physical neglect and sexual abuse—predicted higher and/or extended inflammatory stress responses. In turn, higher inflammatory stress responses related to greater pregnancy and birth complications, and extended inflammatory responses related to a greater likelihood of preterm birth. Findings support oral inflammatory response to stress as a potential link to target in intergenerational health risk transmission.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148359667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal Early Pregnancy Tetrahydrocannabinol (THC) Metabolites Correlate With Newborn Resting-State Functional Connectivity 孕妇妊娠早期四氢大麻酚（THC）代谢物与新生儿静息状态功能连接相关。

IF 1.9 4区心理学

Developmental psychobiology Pub Date : 2026-06-25 DOI: 10.1002/dev.70179

Chaela Nutor, Jocelyn Stanfield, Patricia A. Brennan, Dana Boyd Barr, Anne L. Dunlop, Cassandra L. Hendrix

{"title":"Maternal Early Pregnancy Tetrahydrocannabinol (THC) Metabolites Correlate With Newborn Resting-State Functional Connectivity","authors":"Chaela Nutor, Jocelyn Stanfield, Patricia A. Brennan, Dana Boyd Barr, Anne L. Dunlop, Cassandra L. Hendrix","doi":"10.1002/dev.70179","DOIUrl":"10.1002/dev.70179","url":null,"abstract":"<div>\u0000 \u0000 Growing evidence in preclinical and clinical models suggests that prenatal cannabis exposure (PCE) is associated with changes in brain functioning and behavior. This observational longitudinal study examines these associations using biological measures of PCE in a sample of Black mother-infant dyads (N = 42), who have historically been underrepresented in developmental neuroimaging studies. Maternal urine samples collected during pregnancy (8–14 weeks of gestation) were assayed for 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (COOH-THC) metabolites, providing a biologically verified measure of prenatal cannabis exposure. Newborns (57% female) completed a resting-state fMRI scan and were assessed using the NICU Network Neurobehavioral Scale at approximately 1 month postpartum. We performed voxelwise seed connectivity analyses using seeds in the bilateral hippocampus, insula, and caudate. We found that COOH-THC levels in early pregnancy were significantly associated with altered connectivity patterns in the hippocampus, insula, and caudate in infants. These functional connectivity patterns, however, were not correlated with indices of newborn neurobehavior. These preliminary results suggest that cannabis exposure early in pregnancy may impact neural connectivity shortly after birth, with effects that withstand the influence of co-occurring maternal psychosocial factors.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148316192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epigenetic Mechanisms Linking Maternal Stress During Pregnancy to Autism Spectrum Disorders: A Narrative Review 妊娠期间母亲压力与自闭症谱系障碍相关的表观遗传机制：综述。

IF 1.9 4区心理学

Developmental psychobiology Pub Date : 2026-06-16 DOI: 10.1002/dev.70173

Konstantina Kelaidoni, Konstantinos M. Kotsis

{"title":"Epigenetic Mechanisms Linking Maternal Stress During Pregnancy to Autism Spectrum Disorders: A Narrative Review","authors":"Konstantina Kelaidoni, Konstantinos M. Kotsis","doi":"10.1002/dev.70173","DOIUrl":"10.1002/dev.70173","url":null,"abstract":"<div>\u0000 \u0000 Autism Spectrum Disorders (ASD) are a heterogeneous group of neurodevelopmental conditions characterized by deficits in social communication and the presence of restricted, repetitive behaviors. While genetic factors contribute substantially to ASD etiology, growing evidence highlights the role of environmental and epigenetic factors, with maternal stress during pregnancy emerging as a potential determinant of fetal brain development. Prenatal stress may alter the intrauterine environment through modulation of the hypothalamic–pituitary–adrenal (HPA) axis and changes in glucocorticoid signaling. These physiological responses have been associated with epigenetic modifications, such as DNA methylation, histone post-translational modifications, and alterations in non-coding RNA expression although causal pathways remain under investigation. Consequently, gene expression programs critical for neuronal proliferation, migration, synaptogenesis, and stress–response maturation are reshaped. Converging evidence from human cohorts and animal models indicates that these stress-induced epigenetic changes affect genes such as NR3C1, FKBP5, BDNF, OXTR, and SHANK3, contributing to altered stress response, impaired synaptic plasticity, and disrupted neural connectivity. Foundational studies before 2020 established the basic mechanistic link between prenatal stress, glucocorticoid exposure, and epigenetic gene regulation, forming a basis for the 2020–2025 literature summarized here. This narrative review synthesizes research published between 2020 and 2025, integrating molecular, epidemiological, and neurodevelopmental perspectives to elucidate how prenatal stress induces lasting neurobiological changes, thereby advancing the conceptual framework for early detection and intervention in ASD.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148263818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating Stress: Exploring the Role of Empathy in Caregiving 导航压力：探讨共情在照顾中的作用。

IF 1.9 4区心理学

Developmental psychobiology Pub Date : 2026-06-16 DOI: 10.1002/dev.70177

Hannah Spencer, Peter A. Bos, Sabine van der Asdonk, Lenneke R. A. Alink, Renate S. M. Buisman

{"title":"Navigating Stress: Exploring the Role of Empathy in Caregiving","authors":"Hannah Spencer, Peter A. Bos, Sabine van der Asdonk, Lenneke R. A. Alink, Renate S. M. Buisman","doi":"10.1002/dev.70177","DOIUrl":"10.1002/dev.70177","url":null,"abstract":"Stress can negatively impact caregiving behavior; while chronic stress is consistently associated with reduced caregiver sensitivity, evidence regarding acute stress remains mixed. This preregistered study examined the causal effects of acute psychosocial stress on caregiver sensitivity with an experimental pseudorandomized design. Female participants (N = 130, Mage = 21.16, SD = 1.65) were assigned to either an adapted Trier Social Stress Test or a control condition, and then interacted with an infant simulator while their caregiver sensitivity was observed. We also investigated the role of situational empathic behavior and trait empathic concern in the relationship between acute stress and caregiver sensitivity. Structural equation modeling demonstrated that acute stress did not significantly decrease caregiver sensitivity. Furthermore, situational empathic behavior did not explain how acute stress affected caregiver sensitivity, nor did trait empathic concern influence how acute stress affected situational empathic behavior. However, trait empathic concern was positively associated with caregiver sensitivity, affirming that empathy is fundamental to caregiving. We discuss that effects of acute stress may be more subtle compared to chronic stress and highlight the importance of sensitive measurement instruments in continued research, which will help us to further understand how stress impacts caregiving and, consequently, child outcomes.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148263859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Children With Idiopathic Toe Walking Display Different Cortical Activation Patterns When Interpreting Tactile Sensation 特发性足趾行走患儿在解读触觉时表现出不同的皮层激活模式。

IF 1.9 4区心理学

Developmental psychobiology Pub Date : 2026-06-16 DOI: 10.1002/dev.70168

Jack H. Donne, Richard Beare, Jennifer A. Powell, Michael C. Fahey, Cylie M. Williams

{"title":"Children With Idiopathic Toe Walking Display Different Cortical Activation Patterns When Interpreting Tactile Sensation","authors":"Jack H. Donne, Richard Beare, Jennifer A. Powell, Michael C. Fahey, Cylie M. Williams","doi":"10.1002/dev.70168","DOIUrl":"10.1002/dev.70168","url":null,"abstract":"Idiopathic toe walking (ITW) is a diagnosis given to children who walk with an absence of heel strike in the contact phase of the gait cycle, who are otherwise typically developing. This study aimed to determine if children with ITW had cortical activation differences when completing a tactile sensation test compared to typically developing children. The study included 15 typically developing children and 15 children with ITW. Participants were required to perform a two-point discrimination test during an fMRI using a standard block design.Four clusters were identified, where the controls exhibited significantly greater activation than the ITW group during the tactile test. The largest cluster peaked in the right inferior frontal gyrus. A second cluster was centered in the right middle frontal gyrus. The third cluster peaked in the right inferior parietal lobule. Lastly, a smaller cluster was identified in the right precuneus.The results indicate that the control group exhibited greater activation than the ITW group in key brain regions involved in executive function, motor planning, and sensory integration. These findings support the notion that ITW is linked to functional differences in neural networks related to motor control and sensory integration.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70168","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148263887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic Variability in OXTR Polymorphism and Infant Reactivity to Ostracism Experiences OXTR多态性的遗传变异与婴儿对排斥经历的反应。

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2026-06-08 DOI: 10.1002/dev.70175

Testa Alessia, Quadrelli Ermanno, Dall'Olio Valentina, Tizzoni Laura, Peterlongo Paolo, Bulf Hermann, Turati Chiara

{"title":"Genetic Variability in OXTR Polymorphism and Infant Reactivity to Ostracism Experiences","authors":"Testa Alessia, Quadrelli Ermanno, Dall'Olio Valentina, Tizzoni Laura, Peterlongo Paolo, Bulf Hermann, Turati Chiara","doi":"10.1002/dev.70175","DOIUrl":"10.1002/dev.70175","url":null,"abstract":"The oxytocin system is central to regulating social behaviors, with genetic variations in the oxytocin receptor gene (OXTR), particularly the rs53576 single nucleotide polymorphism (SNP), linked to individual differences in emotional reactivity and social cognition. GG genotype carriers typically show heightened sensitivity to social dynamics, exhibiting greater empathy and prosocial behaviors in positive contexts but also increased anxiety and emotional dysregulation in response to negative social stressors, such as ostracism. Although these associations are well established in adults, little is known about the impact of genetic variability in the oxytocin system on infants’ behavioral and emotional reactivity to ostracism experiences. The current study investigated whether rs53576 allelic variations influence 13-month-olds’ (N = 56, 41% males; mostly White) affective and behavioral reactions to ostracism episodes during a live-triadic ball-tossing game. Results demonstrated that GG carriers show heightened sensitivity to ostracism compared to AA/AG carriers. Specifically, ostracized GG infants exhibited a more pronounced decrease in Positive Emotionality and an increase in Negative Emotionality. Current findings underscore the role of genetic predispositions in enhancing sensitivity to social experiences, shaping infants’ early interactions within their social environment.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70175","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148204433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantifying Visuomotor Maturation From Middle Childhood to Adolescence 量化从童年中期到青春期的视觉运动成熟。

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2026-06-08 DOI: 10.1002/dev.70176

Ewa Niechwiej-Szwedo, Lisa W. Christian

{"title":"Quantifying Visuomotor Maturation From Middle Childhood to Adolescence","authors":"Ewa Niechwiej-Szwedo, Lisa W. Christian","doi":"10.1002/dev.70176","DOIUrl":"10.1002/dev.70176","url":null,"abstract":"Proficiency in fine motor skills improves significantly from childhood into adolescence; however, a longitudinal approach has not been used to examine the maturation trajectory of eye–hand coordination. Capturing individual performance changes by following the same cohort over time could offer unique insight into the developmental processes. This study assessed eye and hand kinematics during the execution of a prehension task in typically developing children (n = 17) tested at two time points: middle childhood (mean age: 9.14 years) and adolescence (mean age: 13.51 years). Results showed significant improvement in overall performance, which was due to shorter fixation duration, faster reaching duration, and shorter object placement duration. Temporal pattern of eye–hand coordination became more mature (adult-like) when picking up an object, indicating efficient coordination between the grasp and reach movements. Results demonstrate that kinematic analysis of prehension and eye–hand coordination provides a sensitive assay of the maturation trajectory of visuohaptic integration during prehension. These findings may support new methods for assessing fine motor skills and enhance the diagnosis of neurodevelopmental disorders linked to visuomotor impairments.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70176","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148204441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Activational Effects of Gonadal Hormones on Social Reward Motivation in Adolescence and Adulthood in Female and Male Long–Evans Rats 性腺激素对雌雄Long-Evans大鼠青春期和成年期社会奖励动机的激活作用。

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2026-06-08 DOI: 10.1002/dev.70174

S. H. Murray, A. M. Randell, F. S. E. Krajcovic, B. C. J. Fletcher, C. M. McCormick

{"title":"Activational Effects of Gonadal Hormones on Social Reward Motivation in Adolescence and Adulthood in Female and Male Long–Evans Rats","authors":"S. H. Murray, A. M. Randell, F. S. E. Krajcovic, B. C. J. Fletcher, C. M. McCormick","doi":"10.1002/dev.70174","DOIUrl":"10.1002/dev.70174","url":null,"abstract":"There are age and sex differences in the processing of social reward, although the basis for these differences is not well established. We previously found greater social motivation at P50 (postpubertal adolescence) than at P70 (adulthood), and that female rats showed greater social motivation than male rats. Thus, we investigated whether gonadal hormones may contribute to age and sex differences in social reward motivation. Rats underwent either gonadectomy or sham surgery at P41 (adolescent group) or P69 (adult group) and began testing in the operant conditioning paradigm 5 days later. When trained on a fixed ratio of one, gonadectomized rats had a greater social preference relative to control rats, irrespective of sex and age. When tested on a progressive ratio (effort required to access social reward continually increased), adolescents were more motivated than were adults, irrespective of sex or gonadal status. However, resistance to extinction was evident in gonadectomized rats relative to control rats, irrespective of sex and age. Thus, the results provide evidence that gonadal hormones influence social preference, although not social motivation. Ongoing maturation, rather than puberty, is responsible for age-related changes in social reward motivation, and the presence of gonadal hormones independently influences the preference for a social partner.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70174","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148204367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal Separation Reduces Hypothalamic Interleukin-6 Expression and Enhances Microglial Activation During Critical Developmental Windows 母体分离降低下丘脑白细胞介素-6表达并增强关键发育窗口期小胶质细胞的激活。

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2026-05-31 DOI: 10.1002/dev.70172

Angelica Roque, Bryan Phillips-Farfán, Naima Lajud, Esperanza Meléndez-Herrera

{"title":"Maternal Separation Reduces Hypothalamic Interleukin-6 Expression and Enhances Microglial Activation During Critical Developmental Windows","authors":"Angelica Roque, Bryan Phillips-Farfán, Naima Lajud, Esperanza Meléndez-Herrera","doi":"10.1002/dev.70172","DOIUrl":"10.1002/dev.70172","url":null,"abstract":"<div>\u0000 \u0000 Early life stress, caused by maternal separation (MS), increases hippocampal inflammatory markers in neonates. However, the effects of MS on hypothalamic neuroimmune development and the peripheral immune response have not yet been assessed. This study examined the effect of MS on neuroimmune and synaptic development by evaluating the expression of pro- and anti-inflammatory cytokines and their association with synaptic plasticity markers in the hypothalamus and hippocampus throughout postnatal development. Microglial activation was analyzed in both brain regions at postnatal day 15 (P15), and the systemic immune response was measured through hemolytic capacity. Cytokine and synaptophysin expression showed dynamic, region-specific changes across postnatal development. MS reduced hypothalamic interleukin 6 expression at P6 and P12, enhanced microglial activation at P15, and blunted the developmental increase in hemolytic capacity seen in controls at P21. While control animals exhibited region-specific associations between cytokines and synaptic markers, these relationships were attenuated in the MS group, including a differential interleukin 6–synaptophysin association. These results suggest that MS alters hypothalamic neuroimmune relationships and systemic immune responses during critical developmental windows. Additionally, increased microglial activation at P15 suggests that MS induced proinflammatory, region-specific changes. These alterations may contribute to heightened vulnerability to mental disease later in life.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148136981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diminished Performance and Learning of a Novel Visuomotor Skill in Children Born Preterm 早产儿一项新的视觉运动技能的学习与表现减弱。

IF 2.2 4区心理学

Developmental psychobiology Pub Date : 2026-05-29 DOI: 10.1002/dev.70169

Samuel T. Nemanich, Cassandra Kemmel-Bartletti, Md Raihan Mia, Iqbal Ahamed, Naveen Bansal

{"title":"Diminished Performance and Learning of a Novel Visuomotor Skill in Children Born Preterm","authors":"Samuel T. Nemanich, Cassandra Kemmel-Bartletti, Md Raihan Mia, Iqbal Ahamed, Naveen Bansal","doi":"10.1002/dev.70169","DOIUrl":"10.1002/dev.70169","url":null,"abstract":"<div>\u0000 \u0000 Premature birth has long-term effects on sensory, motor, and cognitive development. Despite evidence of impaired motor function in young children born preterm, there is less known about motor learning and the characterization of the acquisition and retention of motor skills in this population. Furthermore, bimanual movements, important for performing everyday activities, may be preferentially affected in preterm children. In this study, we compared unimanual and bimanual motor skill learning in young children born preterm compared to children born at term age. Unimanual and bimanual de novo visuomotor learning tasks were implemented on a computerized tablet (Apple iPad). Fifty-five participants (N = 14 preterm), corrected age 5–8 years, completed three testing sessions: initial practice (72 practice attempts), 24-h retention (24 practice attempts), and 7-day retention (24 practice attempts). Speed (completion time) and accuracy (movement path length) characterized motor performance. Learning was determined by comparing performance at the end of initial practice to each retention test. Overall, preterm children exhibited reduced speed and accuracy on both tasks compared to term-born children. All children performed better on the unimanual version of the task. Retention was similar between groups and tasks. Biological age had a small, nonlinear relationship with performance. These results confirm that preterm children have impaired unimanual and bimanual skills but are capable of learning new visuomotor patterns, with potential differences in skill retention. This evidence provides insight into the varied trajectories of motor development of preterm children.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148053244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0