Developmental psychobiology最新文献_第4页

Brief Report: An Examination of Curvilinear Relations Between Perceived Mother–Child Closeness and Maternal Hair Cortisol 简要报告：对感知到的母子亲密程度与母体毛发皮质醇之间曲线关系的研究

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-09-13 DOI: 10.1002/dev.22548

Kavya Swaminathan, Samantha MacDonald, Stacey Doan

{"title":"Brief Report: An Examination of Curvilinear Relations Between Perceived Mother–Child Closeness and Maternal Hair Cortisol","authors":"Kavya Swaminathan, Samantha MacDonald, Stacey Doan","doi":"10.1002/dev.22548","DOIUrl":"https://doi.org/10.1002/dev.22548","url":null,"abstract":"<div>\u0000 \u0000 Interpersonal closeness has important health benefits; however, recent work suggests that in certain contexts, closeness can come at a cost. In the current study, curvilinear relations between mother–child closeness and health (e.g., depressive and anxiety symptoms and hair cortisol concentrations [HCC]) were tested. Our sample consisted of 117 mother (Mage = 36.86) and child (Mage = 73.07 months, 50.86% male) dyads. A quadratic relationship between maternal perceived closeness with their child and self-reported depressive and anxiety symptoms, along with overall hair cortisol output, was hypothesized. Path analysis suggested that the quadratic term was predictive of maternal cortisol (β = 0.28, p = 0.001) and depression (β = 0.23, p = 0.014), such that both high and low perceived closeness predict greater maternal depressive symptoms and HCCs as compared to moderate levels of closeness. Results are discussed in terms of parenting support and burnout.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142230977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Attention Deficit Hyperactivity Disorder, Cannabis Use, and the Endocannabinoid System: A Scoping Review 注意缺陷多动障碍、大麻使用和内源性大麻素系统：范围综述

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-09-13 DOI: 10.1002/dev.22540

Jennie E. Ryan, Mitchell Fruchtman, Andrea Sparr-Jaswa, Amy Knehans, Brooke Worster

{"title":"Attention Deficit Hyperactivity Disorder, Cannabis Use, and the Endocannabinoid System: A Scoping Review","authors":"Jennie E. Ryan, Mitchell Fruchtman, Andrea Sparr-Jaswa, Amy Knehans, Brooke Worster","doi":"10.1002/dev.22540","DOIUrl":"https://doi.org/10.1002/dev.22540","url":null,"abstract":"There is emerging evidence that the endocannabinoid system (ECS) plays a significant role in the pathophysiology of many psychiatric disorders, including attention deficit hyperactivity disorder (ADHD). Increasing evidence suggests that a number of neurobiological correlates between endogenous cannabinoid function and cognitive dysfunction are seen in ADHD, making the ECS a possible target for therapeutic interventions. Cannabis use and cannabis use disorder are more prevalent in individuals with ADHD, compared to the general population, and there is growing popular perception that cannabis is therapeutic for ADHD. However, the relationship between cannabis use and ADHD symptomology is poorly understood. Further understanding of the role of the ECS in ADHD pathophysiology and the molecular alterations that may be a target for treatment is needed. To further the science on this emerging area of research, this scoping review describes the preclinical and clinical evidence seeking to understand the relationship between the ECS and ADHD.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22540","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142230975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence of Differential Prediction of Anxiety and Depression by Diurnal Alpha-Amylase and Cortisol in Development 发育过程中昼夜α-淀粉酶和皮质醇对焦虑和抑郁的不同预测证据

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-09-13 DOI: 10.1002/dev.22549

Bethany H. McCurdy, Carl F. Weems, Travis Bradley, Ryan Matlow, Victor G. Carrión

{"title":"Evidence of Differential Prediction of Anxiety and Depression by Diurnal Alpha-Amylase and Cortisol in Development","authors":"Bethany H. McCurdy, Carl F. Weems, Travis Bradley, Ryan Matlow, Victor G. Carrión","doi":"10.1002/dev.22549","DOIUrl":"https://doi.org/10.1002/dev.22549","url":null,"abstract":"Research and theory suggest an important role of neuroendocrine function in emotional development, particularly under conditions of elevated stress. We provide empirical data to clarify associations between alpha-amylase (AA) and cortisol as well as test the differential linkages among AA, cortisol, and symptoms of anxiety, depression, and posttraumatic stress in children. Children recruited from a low-income elevated violence community (n = 100; mean age = 10, SD = 0.64; 79% Latino; 67% received free or reduced lunch) were assessed on diurnal levels of AA and cortisol along with assessments of anxiety, depression, and posttraumatic stress symptoms (PTSS). Elevated anxiety symptoms were associated with steeper linear slopes of AA with higher levels of AA in the morning but lower levels of AA in the evening. Depression was associated with differential cubic trajectories of AA when PTSSs were included in the model. Anxiety also predicted differential cubic diurnal trends in cortisol, such that greater anxiety symptoms were associated with relatively higher levels of cortisol in the evening. Again, depression symptoms when PTSS were included predicted diurnal cubic trends with elevated depression associated with lower awakening and midday cortisol that reversed to higher evening cortisol compared to youth with fewer self-reported depression symptoms.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22549","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142230978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temperament in Early Childhood Is Associated With Gut Microbiota Composition and Diversity 幼儿期的性情与肠道微生物群的组成和多样性有关。

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-09-05 DOI: 10.1002/dev.22542

Eriko Ueda, Michiko Matsunaga, Hideaki Fujihara, Takamasa Kajiwara, Aya K. Takeda, Satoshi Watanabe, Keisuke Hagihara, Masako Myowa

{"title":"Temperament in Early Childhood Is Associated With Gut Microbiota Composition and Diversity","authors":"Eriko Ueda, Michiko Matsunaga, Hideaki Fujihara, Takamasa Kajiwara, Aya K. Takeda, Satoshi Watanabe, Keisuke Hagihara, Masako Myowa","doi":"10.1002/dev.22542","DOIUrl":"10.1002/dev.22542","url":null,"abstract":"Temperament is a key predictor of human mental health and cognitive and emotional development. Although human fear behavior is reportedly associated with gut microbiome in infancy, infant gut microbiota changes dramatically during the first 5 years, when the diversity and composition of gut microbiome are established. This period is crucial for the development of the prefrontal cortex, which is involved in emotion regulation. Therefore, this study investigated the relationship between temperament and gut microbiota in 284 preschool children aged 3–4 years. Child temperament was assessed by maternal reports of the Children's Behavior Questionnaire. Gut microbiota (alpha/beta diversity and genera abundance) was evaluated using 16S rRNA sequencing of stool samples. A low abundance of anti-inflammatory bacteria (e.g., Faecalibacterium) and a high abundance of pro-inflammatory bacteria (e.g., Eggerthella, Flavonifractor) were associated with higher negative emotionality and stress response (i.e., negative affectivity, β = −0.17, p = 0.004) and lower positive emotionality and reward-seeking (i.e., surgency/extraversion, β = 0.15, p = 0.013). Additionally, gut microbiota diversity was associated with speed of response initiation (i.e., impulsivity, a specific aspect of surgency/extraversion, β = 0.16, p = 0.008). This study provides insight into the biological mechanisms of temperament and takes important steps toward identifying predictive markers of psychological/emotional risk.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22542","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Greater Frontoparietal Connectivity During Task Engagement Among Toddlers With Parent-Reported Inattention 家长反映注意力不集中的幼儿在任务参与过程中前额叶连接性更强。

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-09-05 DOI: 10.1002/dev.22546

Heather M. Joseph, Hendrik Santosa, Nadiyah Fisher, Theodore Huppert, Judith K. Morgan

{"title":"Greater Frontoparietal Connectivity During Task Engagement Among Toddlers With Parent-Reported Inattention","authors":"Heather M. Joseph, Hendrik Santosa, Nadiyah Fisher, Theodore Huppert, Judith K. Morgan","doi":"10.1002/dev.22546","DOIUrl":"10.1002/dev.22546","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 Attention-deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with lifelong impairments. ADHD-related behaviors have been observed as early as toddlerhood for children who later develop ADHD. Children with ADHD have disrupted connectivity in neural circuitry involved in executive control of attention, including the prefrontal cortex (PFC) and dorsal attention network (DAN). It is not known if these alterations in connectivity can be identified before the onset of ADHD. Children (N = 51) 1.5–3 years old were assessed using functional near-infrared spectroscopy while engaging with a book. The relation between mother-reported ADHD-related behaviors and neural connectivity, computed using robust innovation-based correlation, was examined. Task engagement was high across the sample and unrelated to ADHD-related behaviors. Observed attention was associated with greater connectivity between the right lateral PFC and the right temporal parietal junction (TPJ). Children with greater ADHD-related behaviors had greater frontoparietal connectivity, particularly between the PFC bilaterally and the right TPJ. Toddlers at risk for developing ADHD may require increased frontoparietal connectivity to sustain attention. Future work is needed to examine early interventions that enhance developing attention and their effect on neural connectivity between the PFC and attention networks.\u0000 </section>\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22546","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Peripubertal Experiences on Competitive Behavior in Male Rats at Different Stages of Adulthood 围青春期经历对不同成年阶段雄性大鼠竞争行为的影响

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-09-05 DOI: 10.1002/dev.22544

Jinkun Huang, Wenjia Yang, Lili Bao, Bin Yin

{"title":"Effects of Peripubertal Experiences on Competitive Behavior in Male Rats at Different Stages of Adulthood","authors":"Jinkun Huang, Wenjia Yang, Lili Bao, Bin Yin","doi":"10.1002/dev.22544","DOIUrl":"10.1002/dev.22544","url":null,"abstract":"<div>\u0000 \u0000 Past studies in animal models have extensively investigated the impact of early life experiences on behavioral development, yet relatively few have specifically examined the implications of peripubertal experiences on the evolution of competitive behavior across distinct stages of adulthood. In the current research, we probed potential differences in competitive behavior during emerging adulthood (3 months old) and middle adulthood (12 months old) in 81 Sprague-Dawley male rats exposed to three different peripubertal (postnatal Days 37–60) environments: an enriched environment (EE), a chronic unpredictable mild stress (CUMS) condition, and a control condition. Anxiety-like behavior served as a positive control in our study. Results revealed significant variations in competitive behavior among the groups during emerging adulthood. The EE group displayed the least anxiety and outperformed their peers in food-reward-oriented competition, whereas the CUMS group excelled in status-driven, agonistic competition. However, these behavioral differentiations gradually attenuated by middle adulthood, at which point the control group began to show an advantage. Our findings suggest that although peripubertal experiences significantly shape competitive behavior in the emerging adulthood stage, this effect diminishes over time and is nearly non-detectable during mid-adulthood, underscoring the fluidity of behavioral development and demonstrating that the effects of peripubertal experiences can be modulated by subsequent life experiences.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive Control Moderates Associations Between Domains of Temperamental Reactivity and Preschoolers’ Social Behaviors 认知控制调节了脾气反应与学龄前儿童社交行为之间的关联。

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-09-05 DOI: 10.1002/dev.22545

Sejal Mistry-Patel, Tristin Nyman-Mallis, Jessica M. Dollar, Jeffrey R. Gagne, Rebecca J. Brooker

{"title":"Cognitive Control Moderates Associations Between Domains of Temperamental Reactivity and Preschoolers’ Social Behaviors","authors":"Sejal Mistry-Patel, Tristin Nyman-Mallis, Jessica M. Dollar, Jeffrey R. Gagne, Rebecca J. Brooker","doi":"10.1002/dev.22545","DOIUrl":"10.1002/dev.22545","url":null,"abstract":"Temperamental characteristics and emerging cognitive control are meaningful predictors of children's development of adaptive and maladaptive social behaviors during the preschool period. However, knowledge of the interplay of these pathways, when examined concurrently to highlight their individual contributions, is limited. Using a cross-sectional sample of 3-year-old children, we examined parent-reported discrete traits of negative (anger, fear, sadness, and shyness) and positive (low- and high-intensity pleasure) temperamental reactivity as predictors of children's prosociality and physical aggression. Further, we tested whether the effects of discrete temperament were moderated by cognitive control, as indexed by the N2 event-related potential, during a go/no-go task. Analyses focus on a subsample of children with an observable N2 (n = 66). When controlling for other relative temperament traits, several significant main effects emerged. Moreover, at low cognitive control (smaller N2), fear was negatively associated with aggression, whereas at high cognitive control, sadness was positively associated with aggression. Heightened anger was linked to reduced prosocial behavior when cognitive control was low but linked to greater prosocial behavior when cognitive control was high. The results highlight that discrete temperament traits predict individual differences in child outcomes but that associations depend on concurrent levels of cognitive control.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22545","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Agomelatine Is Unable to Attenuate Kainic Acid–Induced Deficits in Early Life Communicative Behavior 阿戈美拉汀无法减轻凯宁酸诱导的早期沟通行为障碍

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-08-28 DOI: 10.1002/dev.22543

Matthew S. Binder, Zachary J. Pranske, Samantha L. Hodges, Paige D. Womble, Eliesse M. Kwok, Saul I. Quintero, Andrew D. Kim, David A. Narvaiz, Joaquin N. Lugo

{"title":"Agomelatine Is Unable to Attenuate Kainic Acid–Induced Deficits in Early Life Communicative Behavior","authors":"Matthew S. Binder, Zachary J. Pranske, Samantha L. Hodges, Paige D. Womble, Eliesse M. Kwok, Saul I. Quintero, Andrew D. Kim, David A. Narvaiz, Joaquin N. Lugo","doi":"10.1002/dev.22543","DOIUrl":"https://doi.org/10.1002/dev.22543","url":null,"abstract":"Early life seizures are associated with a variety of behavioral comorbidities. Among the most prevalent of these are deficits in communication. Auditory communicative behaviors in mice, known as ultrasonic vocalizations (USVs), can be used to assess potential treatments. Agomelatine is a melatonin agonist that effectively reduces behavioral comorbidities of seizures in adults; however, its ability to attenuate seizure-induced communicative deficits in neonates is unknown. To address this, we administered C57 mice either saline or kainic acid (KA) on postnatal day (PD) 10. The mice then received either agomelatine or saline 1-h post-status epilepticus. On PD 11, we assessed the quantity of USVs produced, the duration, peak frequency, fundamental frequency, and amplitude of the vocalizations, as well as the call type utilization. We found that KA increased vocal production and reduced USV variability relative to controls. KA also increased USV duration and amplitude and significantly altered the types of calls produced. Agomelatine did not attenuate any of the deficits. Our study is the first to assess agomelatine's efficacy to correct USVs and thus provides an important point of context to the literature, indicating that despite its high therapeutic efficacy to attenuate other behavioral comorbidities of seizures, agomelatine's ability to correct neonatal communicative deficits is limited.","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.22543","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142100097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developmental Changes in How Head Orientation Structures Infants’ Visual Attention 头部方向如何构建婴儿视觉注意力的发育变化

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-08-27 DOI: 10.1002/dev.22538

John M. Franchak, Linda Smith, Chen Yu

{"title":"Developmental Changes in How Head Orientation Structures Infants’ Visual Attention","authors":"John M. Franchak, Linda Smith, Chen Yu","doi":"10.1002/dev.22538","DOIUrl":"10.1002/dev.22538","url":null,"abstract":"<div>\u0000 \u0000 Most studies of developing visual attention are conducted using screen-based tasks in which infants move their eyes to select where to look. However, real-world visual exploration entails active movements of both eyes and head to bring relevant areas in view. Thus, relatively little is known about how infants coordinate their eyes and heads to structure their visual experiences. Infants were tested every 3 months from 9 to 24 months while they played with their caregiver and three toys while sitting in a highchair at a table. Infants wore a head-mounted eye tracker that measured eye movement toward each of the visual targets (caregiver's face and toys) and how targets were oriented within the head-centered field of view (FOV). With age, infants increasingly aligned novel toys in the center of their head-centered FOV at the expense of their caregiver's face. Both faces and toys were better centered in view during longer looking events, suggesting that infants of all ages aligned their eyes and head to sustain attention. The bias in infants’ head-centered FOV could not be accounted for by manual action: Held toys were more poorly centered compared with non-held toys. We discuss developmental factors—attentional, motoric, cognitive, and social—that may explain why infants increasingly adopted biased viewpoints with age.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex-Specific Impacts of Early Life Sleep Disruption: Ethanol Seeking, Social Interaction, and Anxiety Are Differentially Altered in Adolescent Prairie Voles 早期睡眠中断对不同性别的影响：青春期草原田鼠的乙醇寻求、社会交往和焦虑发生了不同程度的改变。

IF 1.8 4区心理学

Developmental psychobiology Pub Date : 2024-08-27 DOI: 10.1002/dev.22541

Darren E. Ginder, Carolyn E. Tinsley, Mara E. Kaiser, Miranda M. Lim

{"title":"Sex-Specific Impacts of Early Life Sleep Disruption: Ethanol Seeking, Social Interaction, and Anxiety Are Differentially Altered in Adolescent Prairie Voles","authors":"Darren E. Ginder, Carolyn E. Tinsley, Mara E. Kaiser, Miranda M. Lim","doi":"10.1002/dev.22541","DOIUrl":"10.1002/dev.22541","url":null,"abstract":"<div>\u0000 \u0000 Early life sleep is important for neuronal development. Using the highly social prairie vole rodent model, we have previously reported that early life sleep disruption (ELSD) during the preweaning period results in interference with social bonding and increases ethanol consumption following a stressor in adulthood. Furthermore, ELSD increases parvalbumin expression and reduces glutamatergic neurotransmission in cortical regions in adult prairie voles. To understand the impact of ELSD on the lifespan, an examination of an earlier time in life is necessary. The aim of the present study was to examine behavioral outcomes of ELSD on adolescent prairie voles. Given the known effects of ELSD on development of neuronal systems involved in mood and social motivation, we hypothesized that anxiety, risk, and reward-related behaviors would be impacted by ELSD in adolescent prairie voles. We report that both male and female adolescent prairie voles that experienced ELSD showed heightened anxiety-like behavior compared to age-matched controls (CONs) as measured by a light–dark box. Additionally, both male and female ELSD voles showed reductions in both ethanol preference and consumption, and affiliative behavior compared to CONs. These results suggest that adolescent prairie voles of both sexes experience heightened anxiety-like behavior and reduced reward-seeking behaviors after ELSD. These results further suggest that early life sleep is critically important for neurotypical behaviors in adolescence.\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"66 7","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0