Case Reports in Oncology最新文献

{"title":"Rare Extraskeletal Ewing Sarcoma of the Anterior Abdominal Wall: A Diagnostic Challenge.","authors":"Saurabh Raj, Debanjan Nandi, Rudrakshi Mahaldar","doi":"10.1159/000547251","DOIUrl":"https://doi.org/10.1159/000547251","url":null,"abstract":"<p><strong>Introduction: </strong>Ewing sarcoma (ES) is a highly malignant neoplasm, typically arising from bone in children and young adults. Extraskeletal Ewing sarcoma (EES), involving soft tissues without bone involvement, represents a small fraction of ES cases. Even rarer is its manifestation in the anterior abdominal wall.</p><p><strong>Case presentation: </strong>We report a case of a 27-year-old male presenting with right iliac fossa pain and a palpable mass, ultimately diagnosed as EES of the anterior abdominal wall. Radiological imaging revealed a soft tissue tumour within the rectus sheath with evidence of pulmonary metastasis. Histopathological analysis revealed small round blue cells, and immunohistochemistry demonstrated strong positivity for CD99, FLI1, WT1, and synaptophysin, confirming the diagnosis. Treatment was initiated with multi-agent chemotherapy and radiotherapy, and the patient remains under ongoing follow-up.</p><p><strong>Conclusion: </strong>This case underscores the diagnostic challenge EES poses in atypical locations, requiring a high index of suspicion and a multimodal diagnostic and therapeutic approach.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1123-1128"},"PeriodicalIF":0.7,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145250021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PDL1 Expression and Outcomes in Histiocytic Neoplasms.","authors":"Matthew J Moon, Mohammed M Milhem, John M Rieth","doi":"10.1159/000546447","DOIUrl":"10.1159/000546447","url":null,"abstract":"<p><strong>Introduction: </strong>Histiocytic sarcoma (HS) and interdigitating dendritic cell sarcoma (IDCS) are both extremely rare and aggressive histiocytic neoplasms that are most often treated with lymphoma-based chemotherapy; however, there is growing use of immune checkpoint inhibitors (ICI) in the second- or further-line settings as prognosis is typically poor in these neoplasms.</p><p><strong>Case presentations: </strong>We describe two cases: first, HS in a 60-year-old man with primary tumor in the right anterior lower limb, and second, IDCS in an 82-year-old man in the right para-parotid region after initial wide local excision of a right postauricular mass suggestive of a pleomorphic undifferentiated sarcoma. Systemic imaging showed retroperitoneal, inguinal, and pelvic adenopathy in the first case and no distant metastases in the second case. Both were diagnosed via biopsy with extensive immunohistochemistry and were also found to be strongly positive on PDL1 testing. Treatment was initiated with ICIs in both patients, which was paired with palliative radiotherapy for the HS patient. Both cases exhibited a durable response to treatment upon repeated systemic imaging.</p><p><strong>Conclusion: </strong>To our knowledge, these are the first-reported cases of the use of ICIs in the first-line setting in these histiocytic neoplasms and highlight their efficacy. The significant elevation in PDL1 expression seen in both cases may serve as a potential biomarker of excellent response in these neoplasms.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1050-1056"},"PeriodicalIF":0.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small Duodenal Adenocarcinoma with Peritoneal Dissemination Mimicking Duodenal Brunner's Gland Hyperplasia.","authors":"Masao Yoshida, Yoichi Yamamoto, Hiroyuki Ono","doi":"10.1159/000547237","DOIUrl":"10.1159/000547237","url":null,"abstract":"<p><strong>Introduction: </strong>Gastric-phenotype non-ampullary duodenal carcinomas are rare but potentially aggressive tumors.</p><p><strong>Case presentation: </strong>A 52-year-old woman was referred for a duodenal polyp. Endoscopy revealed multiple duodenal bulb polyps suggestive of Brunner's gland hyperplasia. Histopathology confirmed well-differentiated tubular adenocarcinoma with submucosal invasion and a positive margin. The patient underwent pancreaticoduodenectomy, and residual subserosal carcinoma was detected. Despite adjuvant chemotherapy, liver metastases and peritoneal dissemination developed 7 months postoperatively. The patient died 24 months after surgery.</p><p><strong>Conclusion: </strong>This case highlights the aggressive nature of gastric-phenotype duodenal adenocarcinoma and the need for early radical surgical intervention when vertical margins are positive after endoscopic resection.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1069-1073"},"PeriodicalIF":0.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late-Onset Bilateral Retinoblastoma in Adolescence with Successful Globe Salvage.","authors":"Shreyas Temkar, Nirupama Kasturi, Amit Kumar Deb, Hemanth Ramachandar, Krishna Murali, Renu Puthenvilayil Rajan","doi":"10.1159/000546983","DOIUrl":"10.1159/000546983","url":null,"abstract":"<p><strong>Introduction: </strong>Retinoblastoma (RB) is the most common intraocular malignancy in children, known to occur within 5 years of age. The occurrence of RB after the first decade of life is rare and is usually unilateral. Owing to its varied and delayed presentation with advanced stages, enucleation is advocated in most cases of late-onset RB. However, with the advent of multiple treatments, such as local therapies, the chances of globe salvage can still be attempted, even in late-onset RB.</p><p><strong>Case presentation: </strong>We report a case of a 14-year-old boy who had active RB in the right eye and retinomas in the left eye. The child was given systemic three-drug chemotherapy (standard VEC regimen) along with intravitreal injection of topotecan for vitreous seeds in the right eye and cryotherapy for the retinomas in the left eye. By 1 year, the right eye lesion had shown stable type II regression and no recurrence of vitreous seeds, while the left eye lesions showed type IV regression.</p><p><strong>Conclusion: </strong>This case highlights a case of bilateral late-onset RB with a rare combination of active RB in one eye and retinoma in the other eye. Successful globe salvage was achieved by combining local and systemic approaches, resulting in good anatomical and functional outcomes.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1063-1068"},"PeriodicalIF":0.7,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of False-Negative Results in the One-Step Nucleic Acid Amplification Assay for Sentinel Lymph Node Metastasis in Breast Cancer with Low Cytokeratin 19 Expression.","authors":"Ai Koyanagi, Akinari Kakumoto, Hajime Kuroda, Shogo Baba, Mami Koketsu, Oi Harada, Yasutaka Kato, Hiroshi Nishihara, Hiroyuki Kawami","doi":"10.1159/000546995","DOIUrl":"10.1159/000546995","url":null,"abstract":"<p><strong>Introduction: </strong>One-step nucleic acid amplification (OSNA) for the analysis of sentinel lymph nodes is now widely used as a reliable tool for the intraoperative diagnosis of breast cancer metastasis based on the quantification of CK19 mRNA. However, discrepancies have been noted between the molecular diagnosis and histological evaluation, potentially due to differences in tissue sampling or technical limitations. Furthermore, false-negative results may occur when target mRNA expression is reduced.</p><p><strong>Case presentation: </strong>We herein describe a 45-year-old female patient who underwent breast-conserving surgery. The final pathological stage after surgery was pT2N1aM0 (stage IIB), hormone receptor positive (HER2: 1+). An OSNA analysis of two sentinel lymph nodes revealed no metastasis, whereas touch imprint cytology of one of the lymph nodes was positive. Immunohistochemistry of the primary tumor showed a mixture of extensive CK19-negative and focal CK19-positive lesions. A genetic analysis of the CK19-negative lesion detected mutations and abnormalities, including the <i>ESR1</i> amplification, <i>FANCA</i> deletion, <i>STK11</i> deletion, <i>TSC2</i> deletion, <i>POLD1</i> deletion, and mutations in <i>PIK3CA</i>, <i>ARID1A</i>, <i>NF2</i>, <i>SETBP1</i>, and <i>EP300</i>. Of these, tumor heterogeneity and genetic alterations, including mutations in <i>ARID1A</i>, <i>NF2</i>, and <i>EP300</i>, in the CK19-negative lesion were hypothesized to suppress CK19 expression.</p><p><strong>Conclusion: </strong>False-negative results are more likely to occur for CK19-negative breast cancer, emphasizing the importance of incorporating complementary diagnostic methods, such as touch imprint cytology and different molecular markers. A multifaceted diagnostic approach is crucial for ensuring accurate staging and appropriate treatment planning.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1074-1080"},"PeriodicalIF":0.7,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144798278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast-Enhanced Ultrasound of Metastatic Clear Cell Sarcoma of the Liver: A Case Report and Review of the Literature.","authors":"Jian Gong, Jiao-Jiao Ding, Wei-Dong Luo","doi":"10.1159/000547164","DOIUrl":"https://doi.org/10.1159/000547164","url":null,"abstract":"<p><strong>Introduction: </strong>Clear cell sarcoma (CCS) is a rare malignant soft tissue tumor derived from neural crest cells, and it exhibits a high tendency for recurrence and metastasis. Distant metastasis significantly affects the prognosis. The incidence of liver metastasis from CCS is very low, and related contrast-enhanced ultrasound imaging reports are scarce.</p><p><strong>Case report: </strong>We herein report a case involving a 23-year-old Tibetan man who was admitted to the hospital with swelling, pain, and limited movement of the right knee joint. Imaging revealed a tumor in the right knee, and preoperative examinations detected multiple liver lesions. Contrast-enhanced ultrasound showed high enhancement with a thick rim and uneven iso-enhancement in the center during the arterial phase, slow washout of the rim in the portal to delayed phases, and uneven low enhancement centrally. Based on these imaging findings and the patient's history, hepatic tuberculosis was considered, although a tumor could not be ruled out. Laboratory tests - including routine blood, liver function - were normal, and most tumor markers were normal except neuron-specific enolase. The patient underwent surgical resection of the knee tumor, and pathological diagnosis confirmed CCS. The liver lesions were further evaluated with contrast-enhanced computed tomography and enhanced magnetic resonance imaging, but a definitive diagnosis remained elusive. Ultimately, ultrasound-guided needle biopsy confirmed liver metastasis from CCS.</p><p><strong>Conclusion: </strong>Contrast-enhanced ultrasound has a good effect on the diagnosis of liver metastases. Combining with the relevant medical history of the patient or identifying the primary lesion can increase diagnostic confidence.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1111-1122"},"PeriodicalIF":0.7,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Naproxen in High-Temperature Neoplastic Fever: A Case Report Highlighting Its Distinctive Profile among Nonsteroidal Anti-Inflammatory Drugs.","authors":"Rui Li, Yong Chen, ChangYu Deng, Yue Li","doi":"10.1159/000547114","DOIUrl":"10.1159/000547114","url":null,"abstract":"<p><strong>Introduction: </strong>Neoplastic fever (NF) is a relatively common yet frequently underrecognized complication in patients with advanced malignancies. NF is characterized by persistent low-grade fever (typically <38.5°C) driven by tumor-associated cytokine release rather than by infectious or autoimmune causes. As a leading contributor to fever of unknown origin in oncology patients, NF is often difficult to diagnose because of its nonspecific clinical presentation and reliance on exclusion criteria. This case illustrates the diagnostic complexity of NF and highlights the clinical value of targeted antipyretic strategies to support timely oncologic decision-making.</p><p><strong>Case presentation: </strong>A 41-year-old male with stage IVC sigmoid colon adenocarcinoma presented with recurrent high-grade fever (up to 40.4°C), chills, and markedly elevated inflammatory markers (C-reactive protein [CRP]: 202.0 mg/L; procalcitonin: 3.44 ng/mL) over a 2-week period. Comprehensive infectious evaluations, including cultures, antigen testing, and imaging, were all negative. Empirical antibiotics and conventional nonsteroidal anti-inflammatory drugs (NSAIDs) (ibuprofen, diclofenac) failed to achieve sustained defervescence. After ruling out infectious and autoimmune causes and considering chemotherapy-induced tumor lysis, NF was suspected. Administration of 500 mg of naproxen (suppository) led to rapid normalization of temperature (36.4°C) and sustained defervescence. A corresponding decrease in inflammatory markers (CRP: 51.6 mg/L; procalcitonin: 1.70 ng/mL) further confirmed the diagnosis.</p><p><strong>Conclusion: </strong>This case underscores the importance of NF in cancer patients with persistent high-grade fevers who are unresponsive to antimicrobial and standard antipyretic therapies and further demonstrates the distinctive efficacy of naproxen in managing such fevers compared with conventional NSAIDs. Specifically, the rapid and sustained defervescence observed following naproxen administration not only supported the diagnosis but also facilitated the timely continuation of anticancer treatment. Therefore, early recognition of NF and appropriate use of the naproxen test may help avoid unnecessary interventions and ultimately improve patient outcomes.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1004-1011"},"PeriodicalIF":0.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Necrosis of Hepatocellular Carcinoma in Viral B Cirrhosis: A Case Report.","authors":"Yasmine Hidous, Abdelwaheb Nakhli, Emna Mrabet, Nesrine Hemdani, Zeineb Benzarti, Bochra Bouchabou, Rym Ennaifer","doi":"10.1159/000546699","DOIUrl":"10.1159/000546699","url":null,"abstract":"<p><strong>Introduction: </strong>Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide and its prognosis largely depends on the stage at diagnosis and the feasibility of curative treatments. Spontaneous necrosis of HCC is an extremely rare phenomenon with an unclear pathophysiology. Various mechanisms, including vascular disturbances, immune-mediated response, and recurrent infection, have been considered. This case report presents a rare case of spontaneous necrosis of a small HCC in a patient with hepatitis B-related cirrhosis.</p><p><strong>Case presentation: </strong>A 63-year-old male with compensated hepatitis B-related cirrhosis was under routine surveillance when a suspicious liver lesion was detected on ultrasound. Subsequent contrast-enhanced computed tomography (CT) confirmed the presence of an 18-mm HCC in segment VIII, corresponding to Barcelona Clinical Liver Cancer stage A. Due to limited curative treatment options, transarterial chemoembolization was considered. However, a follow-up CT scan was performed 2 weeks before the procedure unexpectedly revealed complete regression of arterial enhancement, suggestive of spontaneous tumor necrosis. The patient remained asymptomatic, with stable liver function and mild biological inflammatory markers. No evidence of vascular thrombosis or significant systemic inflammation was noted, suggesting localized vascular disturbances or intrinsic tumor factors might have precipitated the necrosis.</p><p><strong>Conclusion: </strong>This case highlights the exceptional occurrence of spontaneous necrosis in a small HCC. While the underlying mechanisms remain speculative, further documentation and research on similar cases may provide insights into HCC pathophysiology and potential implications for future therapeutic strategies.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1028-1033"},"PeriodicalIF":0.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12310190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adrenal Incidentaloma Masquerading as Malignancy: A Rare Case of Ganglioneuroma with Nodal Metastasis.","authors":"Shahrukh Memon, Saurabh Raj, Rudrakshi Mahaldar","doi":"10.1159/000547075","DOIUrl":"10.1159/000547075","url":null,"abstract":"<p><strong>Introduction: </strong>Adrenal ganglioneuromas are rare benign tumours, accounting for 0.3%-2% of adrenal incidentalomas. They arise from Schwann and ganglion cells and often mimic adrenal cortical carcinoma clinically and radiologically. Despite their benign nature, metastatic deposits in lymph nodes have been reported, suggesting tumour maturation. Diagnosis is typically confirmed through postoperative histopathology.</p><p><strong>Case presentation: </strong>A male patient in his early 60s with a history of hypertension presented with an adrenal incidentaloma. Imaging revealed a well-defined, hypodense right adrenal mass (35 HU) with calcifications and an enlarged aortocaval lymph node, raising suspicion for carcinoma. Biochemical analysis showed a non-functional adrenal tumour. Intraoperatively, the mass appeared benign, but the lymph node deposit suggested malignancy. Histopathological examination confirmed right adrenal ganglioneuroma with metastatic deposits in the aortocaval lymph nodes. The patient recovered well postoperatively, with normal serum cortisol levels and no signs of recurrence at 6-month follow-up.</p><p><strong>Conclusion: </strong>Adrenal ganglioneuromas can present as adrenal incidentalomas with lymph node involvement, mimicking malignancy. Surgery remains the gold standard for treatment, and postoperative histopathology is crucial for diagnosis. In such cases, no adjuvant therapy or stringent follow-up is required after surgical removal.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1057-1062"},"PeriodicalIF":0.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Administration of a Single Dose of Pembrolizumab, Docetaxel, and Cisplatin Leads to Complete Disappearance of a Locally Advanced Hypopharyngeal Squamous Cell Carcinoma: A Case Report.","authors":"Basil Alzahrani, Mohammed Albin Ahmed, Anas Alzahrani, Abbas Alhejji, Ali Al Zahrani","doi":"10.1159/000547116","DOIUrl":"10.1159/000547116","url":null,"abstract":"<p><strong>Introduction: </strong>Immune-checkpoint inhibition has improved the outcomes of patients with a metastatic squamous cell carcinoma in the head and neck. The combination of pembrolizumab, platinum agent, and 5-fluorouracil had been shown to improve the survival of patients with a positive programmed death ligand 1 (PD-L1) test and had become the standard treatment. Patients with a high combined positive score (CPS) of >20 can be treated solely with pembrolizumab. The treatment is usually continued until disease progression. Induction immunotherapy has also shown benefits.</p><p><strong>Case presentation: </strong>We present a case of a locally advanced hypopharyngeal squamous cell carcinoma in a 63-year-old Arabic man who was started on pembrolizumab, docetaxel, and cisplatin for the first treatment cycle, but he failed to show up for the subsequent cycles due to the coronavirus disease 2019 pandemic restrictions. He came back after 10 months with complete clinical and radiological response.</p><p><strong>Conclusion: </strong>The present report may possibly be the first to report a case of locally advanced squamous cell carcinoma of the hypopharynx that showed complete clinical and radiological response to a single dose of pembrolizumab, docetaxel, and cisplatin.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"1012-1020"},"PeriodicalIF":0.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12306960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}