Bioresources and Bioprocessing最新文献

{"title":"Production of rare ginsenosides by biotransformation of Panax notoginseng saponins using Aspergillus fumigatus.","authors":"Lian Yang, Dongmei Lin, Feixing Li, Xiuming Cui, Dengji Lou, Xiaoyan Yang","doi":"10.1186/s40643-024-00794-0","DOIUrl":"10.1186/s40643-024-00794-0","url":null,"abstract":"<p><p>Panax notoginseng saponins (PNS) are the main active components of Panax notoginseng. But after oral administration, they need to be converted into rare ginsenosides by human gut microbiota and gastric juice before they can be readily absorbed into the bloodstream and exert their effects. The sources of rare ginsenosides are extremely limited in P. notoginseng and other medical plants, which hinders their application in functional foods and drugs. Therefore, the production of rare ginsenosides by the transformation of PNS using Aspergillus fumigatus was studied in this research. During 50 days at 25 ℃ and 150 rpm, A. fumigatus transformed PNS to 14 products (1-14). They were isolated by varied chromatographic methods, such as silica gel column chromatography, Rp-C₁₈ reversed phase column chromatography, semi-preparative HPLC, Sephadex LH-20 gel column chromatography, and elucidated on the basis of their ¹H-NMR, ¹³C-NMR and ESIMS spectroscopic data. Then, the transformed products (1-14) were isolated and identified as Rk₃, Rh₄, 20 (R)-Rh₁, 20 (S)-Protopanaxatriol, C-K, 20 (R)-Rg₃, 20 (S)-Rg₃, 20 (S)-Rg₂, 20 (R)-R₂, Rk₁, Rg₅, 20 (S)-R₂, 20 (R)-Rg₂, and 20 (S)-I_, respectively. In addition, all transformed products (1-14) were tested for their antimicrobial activity. Among them, compounds 5 (C-K) and 7 [20 (S)-Rg₃] showed moderate antimicrobial activities against Staphylococcus aureus and Candida albicans with MIC values of 6.25, 1.25 μg/mL and 1.25, 25 μg/mL, respectively. This study lays the foundation for production of rare ginsenosides.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"11 1","pages":"81"},"PeriodicalIF":4.3,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11319572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a microbial dewaxing agent using three spore forming bacteria.","authors":"Xiaoyan Guo, Xutao Zhao, Lizhu Li, Haibo Jin, Jianjun Wang","doi":"10.1186/s40643-024-00795-z","DOIUrl":"10.1186/s40643-024-00795-z","url":null,"abstract":"<p><p>Microbial enhanced oil recovery (MEOR) is a cost effective and efficient method for recovering residual oil. However, the presence of wax (paraffin) in residual oil can substantially reduce the efficiency of MEOR. Therefore, microbial dewaxing is a critical process in MEOR. In this study, a bacterial dewaxing agent of three spore-forming bacteria was developed. Among these bacteria, Bacillus subtilis GZ6 produced the biosurfactant surfactin. Replacing the promoter of the surfactin synthase gene cluster (srfA), increased the titer of surfactin in this strain from 0.33 g/L to 2.32 g/L. The genetically modified strain produced oil spreading rings with diameters increasing from 3.5 ± 0.1 to 4.1 ± 0.2 cm. The LadA F10L/N133R mutant was created by engineering an alkane monooxygenase (LadA) using site-directed mutagenesis in the Escherichia coli host. Compared to the wild-type enzyme, the resulting mutant exhibited an 11.7-fold increase in catalytic efficiency toward the substrate octadecane. When the mutant (pIMPpladA2mu) was expressed in Geobacillus stearothermophilus GZ178 cells, it exhibited a 2.0-fold increase in octadecane-degrading activity. Cultures of the two modified strains (B. subtilis GZ6 (pg3srfA) and G. stearothermophilus GZ178 (pIMPpladA2mu)) were mixed with the culture of Geobacillus thermodenitrificans GZ156 at a ratio of 5:80:15. The resulting composition increased the rate of wax removal by 35% compared to the composition composed of three native strains. This study successfully developed a multi-strain bacterial agent with enhanced oil wax removal capabilities by genetically engineering two bacterial strains.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"11 1","pages":"80"},"PeriodicalIF":4.3,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11310373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141900988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodegradation: the best solution to the world problem of discarded polymers.","authors":"Jun Wu, Jia Wang, Yicheng Zeng, Xinxiao Sun, Qipeng Yuan, Ling Liu, Xiaolin Shen","doi":"10.1186/s40643-024-00793-1","DOIUrl":"10.1186/s40643-024-00793-1","url":null,"abstract":"<p><p>The widespread use of polymers has made our lives increasingly convenient by offering a more convenient and dependable material. However, the challenge of efficiently decomposing these materials has resulted in a surge of polymer waste, posing environment and health risk. Currently, landfill and incineration treatment approaches have notable shortcomings, prompting a shift towards more eco-friendly and sustainable biodegradation approaches. Biodegradation primarily relies on microorganisms, with research focusing on both solitary bacterial strain and multi-strain communities for polymer biodegradation. Furthermore, directed evolution and rational design of enzyme have significantly contributed to the polymer biodegradation process. However, previous reviews often undervaluing the role of multi-strain communities. In this review, we assess the current state of these three significant fields of research, provide practical solutions to issues with polymer biodegradation, and outline potential future directions for the subject. Ultimately, biodegradation, whether facilitated by single bacteria, multi-strain communities, or engineered enzymes, now represents the most effective method for managing waste polymers.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"11 1","pages":"79"},"PeriodicalIF":4.3,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11306678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancement of astaxanthin accumulation via energy reassignment by removing the flagella of Haematococcus pluvialis.","authors":"Yuyong Hou, Zhile Guo, Zhiyong Liu, Suihao Yan, Meijie Cui, Fangjian Chen, Weijie Wang, Longjiang Yu, Lei Zhao","doi":"10.1186/s40643-024-00789-x","DOIUrl":"10.1186/s40643-024-00789-x","url":null,"abstract":"<p><p>Astaxanthin biosynthesis in Haematococcus pluvialis is driven by energy. However, the effect of the flagella-mediated energy-consuming movement process on astaxanthin accumulation has not been well studied. In this study, the profiles of astaxanthin and NADPH contents in combination with the photosynthetic parameters with or without flagella enabled by pH shock were characterized. The results demonstrated that there was no significant alteration in cell morphology, with the exception of the loss of flagella observed in the pH shock treatment group. In contrast, the astaxanthin content in the flagella removal groups was 62.9%, 62.8% and 91.1% higher than that of the control at 4, 8 and 12 h, respectively. Simultaneously, the increased Y(II) and decreased Y(NO) suggest that cells lacking the flagellar movement process may allocate more energy towards astaxanthin biosynthesis. This finding was verified by NADPH analysis, which revealed higher levels in flagella removal cells. These results provide preliminary insights into the underlying mechanism of astaxanthin accumulation enabled by energy reassignment in movement-lacking cells.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"11 1","pages":"78"},"PeriodicalIF":4.3,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11296984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recombinant GH3 β-glucosidase stimulated by xylose and tolerant to furfural and 5-hydroxymethylfurfural obtained from Aspergillus nidulans.","authors":"Diandra de Andrades, Robson C Alnoch, Gabriela S Alves, Jose C S Salgado, Paula Z Almeida, Gabriela Leila Berto, Fernando Segato, Richard J Ward, Marcos S Buckeridge, Maria de Lourdes T M Polizeli","doi":"10.1186/s40643-024-00784-2","DOIUrl":"10.1186/s40643-024-00784-2","url":null,"abstract":"<p><p>The β-glucosidase gene from Aspergillus nidulans FGSC A4 was cloned and overexpressed in the A. nidulans A773. The resulting purified β-glucosidase, named AnGH3, is a monomeric enzyme with a molecular weight of approximately 80 kDa, as confirmed by SDS-PAGE. Circular dichroism further validated its unique canonical barrel fold (β/α), a feature also observed in the 3D homology model of AnGH3. The most striking aspect of this recombinant enzyme is its robustness, as it retained 100% activity after 24 h of incubation at 45 and 50 ºC and pH 6.0. Even at 55 °C, it maintained 72% of its enzymatic activity after 6 h of incubation at the same pH. The kinetic parameters V_max, K_M, and Kcat/K_M for ρ-nitrophenyl-β-D-glucopyranoside (ρNPG) and cellobiose were also determined. Using ρNPG, the enzyme demonstrated a V_max of 212 U mg ^- 1, K_M of 0.0607 mmol L ^- 1, and K_cat/K_M of 4521 mmol L ^- 1 s ^- 1 when incubated at pH 6.0 and 65 °C. The K_M, V_max, and K_cat/K_M using cellobiose were 2.7 mmol L ^- 1, 57 U mg ^- 1, and 27 mmol ^-1 s ^- 1, respectively. AnGH3 activity was significantly enhanced by xylose and ethanol at concentrations up to 1.5 mol L ^- 1 and 25%, respectively. Even in challenging conditions, at 65 °C and pH 6.0, the enzyme maintained its activity, retaining 100% and 70% of its initial activity in the presence of 200 mmol L ^- 1 furfural and 5-hydroxymethylfurfural (HMF), respectively. The potential of this enzyme was further demonstrated by its application in the saccharification of the forage grass Panicum maximum, where it led to a 48% increase in glucose release after 24 h. These unique characteristics, including high catalytic performance, good thermal stability in hydrolysis temperature, and tolerance to elevated concentrations of ethanol, D-xylose, furfural, and HMF, position this recombinant enzyme as a promising tool in the hydrolysis of lignocellulosic biomass as part of an efficient multi-enzyme cocktail, thereby opening new avenues in the field of biotechnology and enzymology.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"11 1","pages":"77"},"PeriodicalIF":4.3,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11286919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy recovery from syngas and pyrolysis wastewaters with anaerobic mixed cultures","authors":"Alberto Robazza, Anke Neumann","doi":"10.1186/s40643-024-00791-3","DOIUrl":"https://doi.org/10.1186/s40643-024-00791-3","url":null,"abstract":"<p>The anaerobic digestion of aqueous condensate from fast pyrolysis is a promising technology for enhancing carbon and energy recovery from waste. Syngas, another pyrolysis product, could be integrated as a co-substrate to improve process efficiency. However, limited knowledge exists on the co-fermentation of pyrolysis syngas and aqueous condensate by anaerobic cultures and the effects of substrate toxicity. This work investigates the ability of mesophilic and thermophilic anaerobic mixed cultures to co-ferment syngas and the aqueous condensate from either sewage sludge or polyethylene plastics pyrolysis in semi-batch bottle fermentations. It identifies inhibitory concentrations for carboxydotrophic and methanogenic reactions, examines specific component removal and assesses energy recovery potential. The results show successful co-fermentation of syngas and aqueous condensate components like phenols and N-heterocycles. However, the characteristics and load of the aqueous condensates affected process performance and product formation. The toxicity, likely resulting from the synergistic effect of multiple toxicants, depended on the PACs’ composition. At 37 °C, concentrations of 15.6 g_COD/g_VSS and 7.8 g_COD/g_VSS of sewage sludge-derived aqueous condensate inhibited by 50% carboxydotrophic and methanogenic activity, respectively. At 55 °C, loads between 3.9 and 6.8 g_COD/g_VSS inhibited by 50% both reactions. Polyethylene plastics condensate showed higher toxicity, with 2.8 g_COD/g_VSS and 0.3 g_COD/g_VSS at 37 °C decreasing carboxydotrophic and methanogenic rates by 50%. At 55 °C, 0.3 g_COD/g_VSS inhibited by 50% CO uptake rates and methanogenesis. Increasing PAC loads reduced methane production and promoted short-chain carboxylates formation. The recalcitrant components in sewage sludge condensate hindered e-mol recovery, while plastics condensate showed high e-mol recoveries despite the stronger toxicity. Even with challenges posed by substrate toxicity and composition variations, the successful conversion of syngas and aqueous condensates highlights the potential of this technology in advancing carbon and energy recovery from anthropogenic waste streams.</p><h3 data-test=\"abstract-sub-heading\">Graphical Abstract</h3>\u0000","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"69 1","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141776515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, characterizations, and antimicrobial activity of sustainable home furnishing-based waste fabric treated using biobased nanocomposite.","authors":"Eman M Swielam, Zeinab M Hussien, Mohamed S Hasanin","doi":"10.1186/s40643-024-00787-z","DOIUrl":"10.1186/s40643-024-00787-z","url":null,"abstract":"<p><p>Clothing and textile industries are major contributors to environmental pollution including textile manufacturing through garment production, spinning, weaving, and dyeing. In this context, the sustainability textile industry is a big challenge and contributes to serving a large segment of society. Also, textile wastes could be used as a raw material for added-value products. Herein, in this study, recycling of residues fabric was treated with antimicrobial nanocomposite to reach the best use of exhausts and obtain multifunction products of aesthetic via the technical design of the waste raw materials. Besides, solving the unemployment problem by opening fields for small industry projects capable of producing high-value textile artifacts, especially when treated against microbes, can be applied to home furnishings. The waste fabric was treated via green synthesis nanocomposite based on chitosan and in situ prepared ZnONPs and cross-linked with tannic acid. The prepared nanocomposite was characterized using physicochemical analysis including attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and X-ray diffraction (XRD). Additionally, the nanocomposite and treated fabric topographical behavior were studied using scanning electron microscopy (SEM) attachment with energy dispersive X-ray analysis (EDX), and images were processed to evaluate the roughness structure. Additionally, high-resolution transmission electron microscopy (HR-TEM) and dynamic light scattering (DLS) were performed to ensure the size and stability of the nanocomposite. The obtained results affirmed the green synthesis of nanocomposite with a size around 130 nm, as well as the doped ZnONPs average size of 26 nm and treated waste fabric, performed a promising attraction between nanocomposite and fabric fibers. Moreover, the antimicrobial study observed excellent activity of nanocomposite against bacteria and unicellular fungi as well.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"11 1","pages":"75"},"PeriodicalIF":4.3,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11272763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing cellulose-binding protein domains for the development of functionalized cellulose materials.","authors":"Shaowei Li, Guodong Liu","doi":"10.1186/s40643-024-00790-4","DOIUrl":"10.1186/s40643-024-00790-4","url":null,"abstract":"<p><p>Cellulosic materials are attracting increasing research interest because of their abundance, biocompatibility, and biodegradability, making them suitable in multiple industrial and medical applications. Functionalization of cellulose is usually required to improve or expand its properties to meet the requirements of different applications. Cellulose-binding domains (CBDs) found in various proteins have been shown to be powerful tools in the functionalization of cellulose materials. In this review, we firstly introduce the structural characteristics of commonly used CBDs belonging to carbohydrate-binding module families 1, 2 and 3. Then, we summarize four main kinds of methodologies for employing CBDs to modify cellulosic materials (i.e., CBD only, genetic fusion, non-covalent linkage and covalent linkage). Via different approaches, CBDs have been used to improve the material properties of cellulose, immobilize enzymes for biocatalysis, and design various detection tools. To achieve industrial applications, researches for lowering the production cost of CBDs, improving their performance (e.g., stability), and expanding their application scenarios are still in need.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"11 1","pages":"74"},"PeriodicalIF":4.3,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11272768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reparative effects of Schizophyllum commune oat bran fermentation broth on UVB-induced skin inflammation via the JAK/STAT pathway.","authors":"Zixin Song, Jiman Geng, Dongdong Wang, Jiaxuan Fang, Ziwen Wang, Changtao Wang, Meng Li","doi":"10.1186/s40643-024-00792-2","DOIUrl":"10.1186/s40643-024-00792-2","url":null,"abstract":"<p><p>Human immortal keratinocyte cells (HaCaT) are induced with UVB to establish an injury model. This model is utilized to investigate whether oat bran fermentation broth (OBF) has a reparative effect on skin inflammation and damage to the skin barrier caused by UVB irradiation. The results show that compared with unfermented oat bran (OB), OBF exhibits higher structural homogeneity, increased molecular weight size, active substances content, and in vitro antioxidant activity. OBF has a scavenging effect on excess reactive oxygen species (ROS) and increases the intracellular levels of antioxidant enzymes. It was found that OBF has a stronger inhibitory effect on the release of inflammatory factors than OB. It increases the synthesis of AQP3 and FLG proteins while decreasing the secretion of KLK-7. OBF can inhibit the transcription level of inflammatory factors by suppressing the JAK/STAT signaling pathway. Safety experiments demonstrate that OBF has a high safety profile.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"11 1","pages":"73"},"PeriodicalIF":4.3,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11272765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An experimental study on the curing of desert sand using bio-cement.","authors":"Xiao Fu, Wan-Jun Ye","doi":"10.1186/s40643-024-00788-y","DOIUrl":"10.1186/s40643-024-00788-y","url":null,"abstract":"<p><p>In order to promote the development and utilization of desert sand, this study is based on researching the most suitable ratio of bio-cement, analyzing the shear strength and permeability of improved desert sand by combining bio-cement and fly ash, and clarifying the applicability of tap water in bio-cement. The relationship between the two and the microstructural properties was investigated using the results of the straight shear test and the permeability test. The results showed that the urease solution prepared with tap water had a more pronounced temperature resistance. The urea concentration and the corresponding pH environment had a direct effect on the urease activity. The calcium carbonate yield was positively correlated with the calcium concentration, and the urea concentration was higher in the ranges of 1.0-1.5 mol/L. As the enzyme-to-gel ratio decreased, the calcium carbonate precipitate produced per unit volume of urease solution gradually converged to a certain value. The shear strength (increased by 37.9%) and permeability (decreased by about 8.9-68.5%) of the modified desert sand peaked with the increase in fly ash content. The microscopic test results indicated that the fly ash could provide nucleation sites for the bio-cement, effectively improving the mechanical properties of the desert sand. The crystal types of calcium carbonate in the modified desert sand were calcite and aragonite, which were the most stable crystal types. This study provides innovative ideas for interdisciplinary research in the fields of bioengineering, ecology and civil engineering.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"11 1","pages":"72"},"PeriodicalIF":4.3,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11264504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141730998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}