Applied Organometallic Chemistry最新文献

{"title":"Synthesis and Polymerization Activity of Phosphine-Pyrrolido [PN] Titanium and Zirconium Complexes","authors":"Jin Iwasaki,&nbsp;Tomoyuki Toda,&nbsp;Ayana Wakatsuki,&nbsp;Shun Ohta,&nbsp;Kei Nishii,&nbsp;Yoshihiro Matano,&nbsp;Katsuhiko Takenaka","doi":"10.1002/aoc.7928","DOIUrl":"https://doi.org/10.1002/aoc.7928","url":null,"abstract":"<div>\u0000 \u0000 <p>A monoanionic bidentate [PN]-type ligand based on dibenzophosphole was synthesized, and its coordination properties toward titanium and zirconium were investigated. The complexes [PN]M (NR₂)₃ (M = Ti, R = Me; M = Zr, R = Et) were synthesized through the reaction of 4-(1H-pyrrole-2-yl)dibenzophosphole, [PN]H, with three equivalents of Ti (NMe₂)₄ or Zr (NEt₂)₄. Both titanium and zirconium complexes featuring the [PN] ligand were characterized by NMR and elemental analysis. Single-crystal X-ray crystallography unveiled the solid-state structure of [PN]Zr (NEt₂)₃, with the pyrrolido group coordinated to the zirconium center in the η¹-mode. Ethylene polymerization at 0.4 MPa using these complexes and dried modified methylaluminoxane (dMMAO) as a cocatalyst yielded linear polyethylene (PE) with a melting point of 128°C–136°C; the polymerization activity reached up to 64 kg/mol (Zr)·h·bar at 70°C.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inspecting the Antimicrobial, Bio-Catalytic, DNA Interactions, In Vitro Cytotoxicity, and Cell Cycle Analysis Efficiency of Newly Nano-Sized Co (II), Ni (II), Cu (II), and Zn (II) Complexes of Schiff's Base Ligand: Spectroscopic Characterization and Quantum Chemical Calculations","authors":"Ibtisam Mousa,&nbsp;Marwah M. M. Madkhali,&nbsp;Sharah A. Aldulmani,&nbsp;Abdel-Nasser M. A. Alaghaz","doi":"10.1002/aoc.7927","DOIUrl":"https://doi.org/10.1002/aoc.7927","url":null,"abstract":"<div>\u0000 \u0000 <p>Nano-sized bivalent metal complexes of Cu (II) <b>(C1)</b>, Ni (II) <b>(C2)</b>, Co (II) <b>(C3)</b>, and Zn (II) <b>(C4)</b> were prepared and characterized of the form [M(L)₂] where L = 2-((E)-((4-methyl-2-(((E)-thiophen-2-ylmethylene)amino)phenyl)imino)methyl)benzenethiol] (C₁₉H₁₆N₂S₂), M = Cu (II), Ni (II), Co (II), and Zn (II). Elemental analyses, molecular weight calculations, infrared, ¹H, ¹³C, and ¹⁵N NMR, electronic, mass, magnetic susceptibility, and conductivity assessments were employed to evaluate our bivalent metal complexes. DFT studies were used to study the tautomeric equilibrium of the ligand (HL), via the DFTB3LYP technique in connection with a 6–311G* correlation consistent basis set. The metal formed four coordinated with the tridentate N₂S donor Schiff base to form octahedral geometry complexes. The XRD analysis of the divalent metal complexes revealed sharp, intense diffraction peaks, indicating their crystalline nature with nanoscale particle sizes. Additional evidence was provided by EDX, SEM, and AFM images, which also confirmed the uniform distribution across the complex surface. Analysis of the absorption patterns for the nano-sized complexes interaction with CT-DNA signifies that the complexes bind via intercalation, with intrinsic binding constant (<i>K</i>_<i>b</i>) spanning from 4.25 × 10⁵ to 8.34 × 10³ M⁻¹. Nano-sized metal (II) complexes show a higher viscous nature than HL. The cytotoxicity of H-L ligand and its complexes against HCT-116, and M-NFS-60 cells was assessed by the MTT assay. Complex <b>C3</b> shows greater cytotoxic effects compared to Cisplatin on MCF-7 cells. Our flow cytometry data indicate significant levels of apoptosis and cell cycle arresting in both liver and breast cancer cell lines.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Palladium-Imidazole Nanoparticles' Cytotoxic Effects on Colon Cancer Cells: Induction of Cell Cycle Arrest and Apoptosis Mediated via Mitochondria","authors":"Khaled M. Ismail,&nbsp;Safaa S. Hassan,&nbsp;Demiana H. Hanna","doi":"10.1002/aoc.7908","DOIUrl":"https://doi.org/10.1002/aoc.7908","url":null,"abstract":"<div>\u0000 \u0000 <p>The present study emphasized the potential antitumor activity of compound A; [Pd (Im)₂Cl₂], a nano-sized coordination compound with a size of 23.76 nm. Characterization was performed using elemental analysis, molar conductance, magnetic measurement, FTIR, Ultraviolet–visible (UV–vis) spectroscopy, thermal analysis, mass spectrometry, and NMR. The complex showed stability up to 300°C. Furthermore, the compound's formation spontaneity was supported by activation parameters calculated from TGA. The di-aqua form of the separated solid complex, compound B [Pd (Im)₂(H₂O)₂]²⁺, was successfully prepared. The geometry optimization of imidazole and its complexes showed that both complexes were more stable than free imidazole. The cis di-aqua form of [Pd (Im)₂(H₂O)₂]²⁺ exhibits superior stability with a more potent IC₅₀ value of 5.72±0.68 μg/mL. This form demonstrates greater inhibitory impacts on Caco-2 cancer cell proliferation compared to [Pd (Im)₂Cl₂]. Moreover, the cytoxicity of [Pd (Im)₂(H₂O)₂]²⁺ against Caco-2 cells was confirmed by a significant increase in LDH levels in treated Caco-2 cells compared to untreated ones. Treatment with [Pd (Im)₂(H₂O)₂]²⁺ in Caco-2 cells markedly raised the percentage of early and late apoptotic cells, accompanied by Go/G1 phase arrest with a more intense comet nucleus. Apoptosis induction in [Pd (Im)₂(H₂O)₂]²⁺ treated cells was mediated through increased reactive oxygen species (ROS) production. Moreover, [Pd (Im)₂(H₂O)₂]²⁺ markedly raised the expression levels of cleaved Caspase-3, Bax, and P53 in treated Caco-2 cells, while concurrently dropping the levels of Bcl-2, cyclin D1, and CDK4. Overall, these findings indicate that [Pd (Im)₂(H₂O)₂]²⁺ triggers significant cytotoxicity in Caco-2 cancer cells in a dose-dependent manner, primarily via ROS-mediated cell death, possibly via the mitochondrial pathway. Additionally, the active species in selected proteins related to apoptosis and cell cycle arrest were explored and compared with theoretical molecular docking results. The outcomes also validated the safety of using [Pd (Im)₂(H₂O)₂]²⁺ against healthy cells, suggesting it as a promising treatment option for colon cancer in humans.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Graphene Oxide Decorated SiO2/Fe3O4 as a Recyclable Catalyst for the Green Synthesis of Novel Thiazinoazepines via Multicomponent Reaction of Isatoic Anhydrides: Cytotoxic Activity and Theoretical Study","authors":"Marziyeh Mohammadi,&nbsp;Zahra Azizi,&nbsp;Zinatossadat Hossaini","doi":"10.1002/aoc.7898","DOIUrl":"https://doi.org/10.1002/aoc.7898","url":null,"abstract":"<div>\u0000 \u0000 <p>This work investigated the use of a complex technique including isatoic anhydrides, α-haloketones, electron-deficient acetylenic compounds, ammonium acetate, and isothiocyanates in a water-based solution at normal room temperature in the presence of SiO₂/Fe₃O₄@Graphene Oxide. The goal was to generate novel thiazinoazepine molecules with significant yields. The thiazinoazepines that have been synthesized contain NH functional groups with acidic protons and demonstrate notable antioxidant activity. The (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide), MTT assay was utilized to evaluate the cytotoxicity of all the synthesized compounds in vitro against cancer cell lines (MCF-7 and A549) as well as normal cell lines). Cytotoxicity refers to the ability of a compound to kill cells. The derivative <b>6e</b> was shown to be the most potent cytotoxic agent, similar to doxorubicin in its lack of selectivity. Alternatively, compound <b>6b</b> might be considered as a compound that is equally effective but more selective than doxorubicin. Quantum chemical approaches utilizing density functional theory have been utilized to enhance comprehension of reaction mechanisms. The used technology for synthesizing thiazinoazepines provides several advantages, including rapid reaction kinetics, outstanding product yield, and straightforward product isolation.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bi2S3/Eu-Bi12O17CL2 Nanosheets for Photocatalytic Reduction of CO2 to CO","authors":"Yi-Nan Zheng,&nbsp;Xiao-Li Song,&nbsp;Shu-Yan Wang,&nbsp;Li-Guo Gao","doi":"10.1002/aoc.7938","DOIUrl":"https://doi.org/10.1002/aoc.7938","url":null,"abstract":"<div>\u0000 \u0000 <p>Two-dimensional (2D) Eu-Bi₁₂O₁₇Cl₂ nanosheet binary composites modified by Bi₂S₃ nanocrystals were constructed at room temperature using a simple in situ anion-exchange strategy with pure carbon disulfide as a direct sulfur source. The method is simple to prepare, energy efficient, and easy to handle compared to conventional treatments. These biphasic composites were thoroughly characterized by a batch of analytical techniques. XRD, FT-IR, Raman, TEM, and XPS spectroscopies verified the coexistence of the two components in the composites, with Bi₂S₃ uniformly distributed in irregularly shaped nanocrystals of Eu-Bi₁₂O₁₇Cl₂ nanosheets to form intimate interfacial contacts in the heterojunction domain. In addition, oxygen vacancies can be created during the vulcanization process. The synthesized Bi₂S₃/Eu-Bi₁₂O₁₇Cl₂ composites exhibit high photocatalytic efficiency for CO₂ as well as high selectivity for CO under visible-light irradiation. A feasible photocatalytic mechanism was also proposed and tested for reusability. This study reveals the construction of robust Bi₂S₃-containing composites with sufficient oxygen vacancies and enhanced photocatalytic capabilities under moderate conditions.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, Crystal Structure, Formation Mechanism, Theoretical Studies, and Biological Evaluation of Azine-Based Bismuth (III) Complex","authors":"Fei-Hong Yao,&nbsp;Chen-Xuan Tang,&nbsp;Xie-Yu Fan,&nbsp;Yue-You Zheng,&nbsp;Tian-Hong Deng,&nbsp;Can Liu,&nbsp;Xuan-Li He,&nbsp;Yan-Hua Lei,&nbsp;Xu Li,&nbsp;Li-Ming Tao,&nbsp;Chuan-Hua Li","doi":"10.1002/aoc.7922","DOIUrl":"https://doi.org/10.1002/aoc.7922","url":null,"abstract":"<div>\u0000 \u0000 <p>The azine-based bismuth (III) complex [Bi(H₂L¹)(NO₃)₃(H₂O)₂]•H₂O(<b>1a</b>) was synthesized by an equivalent reaction between Schiff base and Bi (NO₃)₃•5H₂O using mannitol as an auxiliary agent. During the formation of the complex (<b>1a</b>), the Schiff base containing 3-methoxy group transformed into 3-methoxysalicylaldehyde azine and further coordinated with Bi^III ion to form a mononuclear Bi^III complex (<b>1a</b>). Bismuth (III) ions were unexpectedly found to catalyze the formation of the azines from Schiff bases derived from pyrazinohydrazide, and their formation mechanism was further studied. Theoretical studies of the complex (<b>1a</b>) involving thermodynamic and electronic properties were done using the density functional theory (DFT) B3LYP method. Furthermore, in vitro biological evaluation showed that the antimicrobial and cytotoxic activities of the complex (<b>1a</b>) were much higher than those of free ligands. The obtained MIC and IC₅₀ values of the complex (<b>1a</b>) were almost close to those of the reference drugs.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Synthesis of New Spiropyrrole Derivatives by Employing Activated Carbonyl Compounds and Graphen Oxide Decorated on Ag@CuO/ZnO NPs or CuO/ZnO NPs: Theoretical and Biological Study","authors":"Nasir Iravani,&nbsp;Marziyeh Mohammadi,&nbsp;Zinatossadat Hossaini","doi":"10.1002/aoc.7859","DOIUrl":"https://doi.org/10.1002/aoc.7859","url":null,"abstract":"<div>\u0000 \u0000 <p>This study focused on investigating the synthesis of new spiropyrrole derivatives with high yields. The two nanocatalyst CuO/ZnO@Graphen Oxide nanocomposites (CuO/ZnO@GO NCs) and Ag/CuO/ZnO@Graphen Oxide (Ag@CuO/ZnO@GO NCs) were employed in a multicomponent reaction at room temperature to synthesize new compounds. The reaction involved isatins, <i>N</i>-alkyl isatins, and ninhydrin as activated carbonyl compounds, ammonium acetate, ethyl 2-arylamino-4-dioxo-4-arylbutanoates, hydrazonoyl chloride, or ethylbromopyruvate in water. Also, the catalytic activity of the green synthesized CuO/ZnO@GO and Ag@CuO/ZnO@GO was evaluated in the reduction of organic pollutants such as 4-nitrophenol (4-NP) in water at mild conditions. The results indicated that the biosynthesized MNCs have very high and effective catalytic activity for organic pollutants within a few seconds. The newly synthesized spiro compounds demonstrate antioxidant activity as a result of two assessment processes conducted by its NH group. In addition, the antibacterial activity of newly created spiro compounds was assessed using a disk distribution method, involving two types of Gram-negative bacteria. These compounds were found to limit the growth of Gram-positive bacteria as well. Also, to better understand the reaction mechanism, density functional theory (DFT)–based quantum chemical methods have been applied. The advantages of this technology encompass rapid response times, high product yields, and uncomplicated catalyst and product separation via simple procedures.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Imine Complexes Incorporating ZrO(II), VO(II), and Pd(II) Cations: Synthesis, DFT Calculation, Molecular Docking, Antimicrobial, and Antitumor Activity","authors":"Shimaa M. Abdel-Fatah,&nbsp;Maram T. Basha,&nbsp;Badriah Saad Al-Farhan,&nbsp;Mohamed R. Shehata,&nbsp;Laila H. Abdel Rahman","doi":"10.1002/aoc.7785","DOIUrl":"https://doi.org/10.1002/aoc.7785","url":null,"abstract":"<div>\u0000 \u0000 <p>Novel imine complexes of ZrO(II), VO(II), and Pd(II) have been synthesized and described using IR, TGA, UV/Vis, and ¹HNMR methods, along with powder X-ray diffraction (XRD), elemental (CHN) analysis, mass spectrometry, molar conductance, and magnetic susceptibility measurements. Conductivity measurements indicate that none of the complexes function as electrolytes. Magnetic susceptibility data confirm the paramagnetism of the VO(II) complex, while ZrO(II) and Pd(II) complexes exhibit diamagnetic properties. Various analyses suggest that divalent cations favor a 1:1 metal-to-ligand ratio. Biological studies demonstrated that all complexes possess significant antimicrobial activity against a range of bacterial and fungal strains. We also observed that the antimicrobial potency of the metal complexes follows the order: ZrO(II) &gt; Pd(II) &gt; VO(II) &gt; H₂A, with the ZrO(II) complex showing the highest inhibition zone (28 mm) against Gram-negative bacteria. The antifungal activity against <i>Aspergillus flavus</i> increases in the order VO(II) &gt; ZrO(II) &gt; Pd(II) &gt; H₂A. Additionally, the complexes exhibit high cytotoxicity against carcinoma cell lines, including the HepG-2, when compared with the clinically proven vinblastine. Density functional theory (DFT) calculations were performed to elucidate the equilibrium geometry of the imine ligand and its complexes at the B3LYP level of theory, using the Gaussian 09 program with 6-311G++(dp) basis set for C, H, O, N, and Cl atoms, and lanl2dz for Pd, V, and Zr atoms. Finally, docking studies revealed potential binding modes at the active sites of bacterial and fungal receptors.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bio-Ag/ZnO@MWCNTs Promoted Green Synthesis of Novel Bis-Pyrimidothiazines: Evaluation of Biological Activity","authors":"Ashraf Sadat Shahvelayati,&nbsp;Faramarz Rostami-Charati,&nbsp;Hannaneh Sadat Shirangi,&nbsp;Seyyed Komeil Hosseini Sfandani","doi":"10.1002/aoc.7787","DOIUrl":"https://doi.org/10.1002/aoc.7787","url":null,"abstract":"<div>\u0000 \u0000 <p>This work investigated the one-pot multicomponent reactions of guanidine, isothiocyanates, and unsaturated 1,3-dicarbonyl compounds in an aqueous media at room temperature using catalytic quantities of Ag/ZnO@MWCNTs which was produced bis-pyrimidothiazines with high yields. This field of study uses diphenyl-picrylhydrazine (DPPH) radical trapping to investigate the antioxidant properties of some generated bis-pyrimidothiazines. Academic studies that are now in progress have focused on investigating the antibacterial properties of compounds that have been created. An experimental process that produced the bis-pyrimidothiazines showed a number of noteworthy characteristics, including quick reaction kinetics, high product yields, and simple catalyst separation from the reaction mixture.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Synthesized Biogenic Ag Nanoparticles With Enhanced Antibacterial, Antifungal, Antibiofilm, and Antioxidant Activities: Catalytic Applications in the ipso-Hydroxylation of Aryl Boronic Acids","authors":"Asit Kumar Das,&nbsp;Md Sattar Ali,&nbsp;Arindam Misra,&nbsp;Sahidul Islam,&nbsp;Binoy Kar,&nbsp;Smritikana Biswas,&nbsp;Gaurav Ghatak,&nbsp;Dasarath Mal,&nbsp;Manik Shit,&nbsp;Malay Dolai,&nbsp;Aniruddha Das","doi":"10.1002/aoc.7796","DOIUrl":"https://doi.org/10.1002/aoc.7796","url":null,"abstract":"<div>\u0000 \u0000 <p>Green synthesis of metal nanoparticles using plant sources is one of the most environmentally sound, economically safer, and operationally simple approaches compared with their physiochemical methods. In this work, we have developed the biogenic synthesis of Ag nanoparticles using the aqueous peel extract of <i>Punica granatum</i> L. fruit, which mitigates the requirement for any hazardous reagents or toxic chemicals. The ultraviolet-visible spectrum confirmed the formation of Ag@PPE NPs with an absorption peak at 420 nm. The X-ray diffraction analysis confirms that the biosynthesized Ag@PPE NPs are crystalline, with a crystallite size of 9.23 nm. SEM and TEM images revealed the spherical morphology of Ag@PPE NPs, with particle sizes ranging from 2 to 20 nm. The biosynthesized Ag@PPE NPs were explored as antimicrobial agents against both Gram-positive (CA-MRSA) and Gram-negative (<i>Escherichia coli</i>) bacteria as well as <i>Candida albicans</i> (ATCC 14053). The mean zone of inhibition against the CA-MRSA group was 15.34 ± 2.5 mm, while it was 12.33 ± 1.5 mm against <i>E. coli</i>. In this study, Ag@PPE NPs demonstrated strong antibiofilm activity and antioxidant activity. Moreover, the catalytic applicability of the synthesized Ag@PPE NPs has been investigated for the oxidative hydroxylation of differently substituted aryl boronic acids into phenols at room temperature. The reaction proceeded efficiently in a short reaction time, and the desired products were obtained with high to excellent yields (82%–94%). Notably, the nanocatalyst can be recovered in five consecutive runs without decreasing its catalytic performance. The plausible mechanism of this <i>ipso</i>-hydroxylation reaction is well presented.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}