Applied Organometallic Chemistry最新文献

{"title":"Design a Novel Recyclable Fe3O4@SiO2-TGDM@Ni MICOF Electrode for CO2 Trap, Electrolyte, and Catalyst for Electro-Carboxylation Reaction","authors":"Mounir Ltifi,&nbsp;Mohamed Farouk,&nbsp;Zaman Abdalhussein Ibadi Alaridhee,&nbsp;Gafur Abdulakimov,&nbsp;Aseel Smerat,&nbsp;Dilafruz Kholmurodova,&nbsp;Nargiza Mukhtarkhanovna Nurillaeva,&nbsp;Rasulbek Eshmetov,&nbsp;Davron Kuronboev,&nbsp;Dushamov Dilshod Azadovich,&nbsp;Raouf Hassan","doi":"10.1002/aoc.70645","DOIUrl":"https://doi.org/10.1002/aoc.70645","url":null,"abstract":"<div>\u0000 \u0000 <p>The design and development of high-performance electrocatalytic systems featuring multiple functionalities, excellent recyclability, and reusability constitute a vital and essential advancement in the field of green chemistry. Such innovative approaches significantly mitigate environmental impacts by substantially reducing the discharge of toxic and hazardous pollutants into ecosystems, while concurrently lowering the operational and production costs associated with chemical processes. In alignment with this principle, a novel magnetic electrode based on Fe₃O₄@SiO₂-TGDM@Ni was strategically designed and developed. Within this core-shell architecture, the Fe₃O₄@SiO₂ component imparts strong magnetic properties that facilitate straightforward recovery and repeated use of the electrode through simple magnetic separation. The triaminoguanidine dimethoxybenzene (TGDM) layer simultaneously functions as an electrolyte mediator/support and a co-catalytic promoter, enhancing overall system efficiency. Meanwhile, the Ni NPs serve as the primary electrocatalyst, and thanks to the integrated magnetic recoverability, the entire electrode can be easily retrieved, reused, and assessed for minimal metal leaching. The practical performance of this multifunctional electrode was rigorously evaluated in the electrocarboxylation reaction. The electrochemical synthesis of 2-phenylpropanoic acid derivatives <b>3(a–l)</b> was performed under remarkably mild conditions (room temperature, iPrOH) using a constant current of 7 mA for just 1 h. These optimized conditions afforded the products in excellent isolated yields between 90% and 97%. Impressively, it maintained robust catalytic activity and structural integrity across up to 10 consecutive recycling cycles with negligible performance degradation. The core-shell structured Fe₃O₄@SiO₂-TGDM@Ni material underwent comprehensive characterization using a wide array of techniques, including SEM, EDS, TEM, FT-IR, BET, TGA, VSM, XPS, CV, ICP-OES and mass spectrometry. Similarly, the resulting 2-phenylpropanoic acids <b>3(a-l)</b> were fully identified and confirmed through melting point determination, ¹H NMR, ¹³C NMR spectroscopy, and elemental analysis (CHN).</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 10","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148862308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Half-Sandwich p-Cymene Ruthenium (II) Complexes of N/S-Donor Imine Ligands: Promising Chemotherapeutic Agent Against HCT116 Colon Cancer Cells","authors":"Basmah Abdulbaset Madkhali,&nbsp;Rais Ahmad Khan,&nbsp;Mohammad Abul Farah,&nbsp;Ibtisam I. BinSharfan,&nbsp;Wajhul Qamar,&nbsp;Waleed A. Q. Hailan,&nbsp;Khalid M. Al-Anazi,&nbsp;Arman D. Hadi,&nbsp;Ali Alsalme","doi":"10.1002/aoc.70643","DOIUrl":"https://doi.org/10.1002/aoc.70643","url":null,"abstract":"<div>\u0000 \u0000 <p>Two half-sandwich (η⁶-<i>p</i>-cymene) ruthenium compounds, <b>Ru-CH₃L</b> and <b>Ru-HL</b>, have been prepared via metal–ligand coordination with ligands <b>CH₃L</b> and <b>HL</b>, respectively. The synthesized compounds were characterized by FT-IR, ¹H NMR, ¹³C NMR, and elemental analysis. The coordination of the ligand to Ru (II) via phenolic-O and imine-N atoms was proved by the single X-ray structure of <b>CH₃L</b>, <b>HL</b>, and <b>Ru-CH₃L</b>. Moreover, the interactions of <b>Ru-CH</b>_<b>3</b><b>L</b> and <b>Ru-HL</b> with HSA were also examined. <b>Ru-CH</b>_<b>3</b><b>L</b> and <b>Ru-HL</b> bind to HSA with moderate affinity and static binding mode. The cytotoxicity of the compounds against HCT116, Caco-2, MCF-7, and HUVECs was evaluated by the MTT test. <b>Ru-CH₃L</b> showed potent activity against HCT116 cells with an IC₅₀ value of 18 μM. We have conducted comprehensive in vitro testing of Ru-CH₃L against HCT116 cells. Treatment with <b>Ru-CH</b>_<b>3</b><b>L</b> in HCT116 cells led to cell shrinkage, cell separation, increased intracellular reactive oxygen species (ROS) production, decreased mitochondrial membrane potential (MMP), and activation of caspase-3/7, culminating in cell apoptosis. Moreover, cell death and G2/M cell cycle arrest were observed.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148848615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mononuclear Copper(I) Complexes With Acylthiourea Ligands as Potential Anticancer Agents Against Pancreatic Cancer: Synthesis, Structural Characterization, DFT Calculations, and Docking Studies","authors":"Najeeb Ullah,&nbsp;Rocío Gabriela Peña Morejon,&nbsp;Jebiti Haribabu,&nbsp;Amir Karim,&nbsp;Rahimeh Eshaghi Malekshah,&nbsp;Sodio C. N. Hsu,&nbsp;Arunachalam Arulraj,&nbsp;Daniel Moraga,&nbsp;Cesar Echeverria,&nbsp;Ramalinga Viswanathan Mangalaraja,&nbsp;Diego Quezada,&nbsp;Varaprasad Kokkarachedu,&nbsp;Iskra A. Signore","doi":"10.1002/aoc.70642","DOIUrl":"https://doi.org/10.1002/aoc.70642","url":null,"abstract":"<div>\u0000 \u0000 <p>In this study, two acylthiourea ligands (<b>L1</b> and <b>L2</b>) were synthesized and coordinated to Cu(I) to afford mononuclear complexes <b>1</b> and <b>2</b> featuring sulfur-bound ligands that generate a three-coordinate Cu(S)₂Br core. Spectroscopic analyses (FT-IR, UV–Vis, ¹H and ¹³C NMR) together with ESI-MS confirmed successful coordination and analogous coordination environments for both complexes. Single-crystal X-ray diffraction (SCXRD) of complex <b>1</b> revealed a distorted trigonal-planar geometry with strong Cu-S interactions and additional stabilization through intermolecular C-H···Br and π···π contacts. Density functional theory (DFT-D3) calculations indicated metal-centered HOMO character, ligand-centered LUMO distribution, and reduced HOMO-LUMO gaps upon coordination, with complex <b>2</b> exhibiting higher softness and electrophilicity consistent with enhanced reactivity. Molecular docking studies against PDGFRA predicted stronger binding affinity for the copper complexes than for the free ligands, with complex <b>2</b> exhibiting the most favorable interaction profile. In vitro cytotoxicity assessed by the MTT assay against pancreatic cancer cell lines (PANC-1, MIA PaCa-2, and AsPC-1) showed that complex <b>2</b> exhibits superior growth inhibition compared with complex <b>1</b> and cisplatin, while maintaining better selectivity toward normal cells, with IC₅₀ values of 16.5 ± 0.1 μM for PANC-1 and MIA PaCa-2 and 8.1 ± 0.4 μM for AsPC-1. Collectively, the structural, computational, and biological findings highlight Cu(I)-acylthiourea complexes as promising candidates for further development as anticancer agents.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148784672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal Oxide/MWCNT–Supported Catalysts for One-Pot Multicomponent Synthesis of Fused Azepine Derivatives: Recent Advances and Biological Relevance","authors":"Kajal Sharma,&nbsp;Pankaj Kumar Jain,&nbsp;Jaya Dwivedi,&nbsp;Sonika Jain","doi":"10.1002/aoc.70637","DOIUrl":"https://doi.org/10.1002/aoc.70637","url":null,"abstract":"<div>\u0000 \u0000 <p>This review highlights recent (2021–2026) advances in the application of metals oxide (Fe₃O₄, CuO, ZnO, Ag, TiO₂, and CdO)@multiwalled carbon nanotubes (MO@MWCNTs)–supported catalysts for the one-pot multicomponent synthesis of fused azepine derivatives with five-, six-, and seven-membered rings, an important class of seven-membered nitrogen-containing heterocycles with diverse pharmacological properties. MO@MWCNTs-supported catalysts have emerged as highly efficient and versatile platforms for promoting one-pot multicomponent reactions (MCRs) owing to exceptional surface area, thermal stability, and tunable functionalization. The synergistic role of MO@MWCNTs in facilitating catalyst dispersion, improving recyclability, and enabling mild reaction conditions is critically discussed. These catalytic systems combine the exceptional surface area, thermal stability, and tunable functionalization of MO@MWCNTs with the reactivity of active catalytic species, enabling enhanced reaction efficiency and selectivity. Emphasis is placed on green synthesis approaches that minimize waste, reduce reaction time, and eliminate harsh conditions or toxic solvents. The synergistic role of MO@MWCNTs in facilitating catalyst dispersion, improving recyclability, and enabling mild reaction conditions is critically discussed.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148784180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"UiO-66-NH2 and Magnetic Fe3O4@Cellu@UiO-66-NH2 Composite as Efficient Supports for Cellulase Immobilization: Synthesis, Characterization, Performance Evaluation, and Reusability","authors":"Siti Unvaresi Misonia Beladona,&nbsp;Meiyanti Ratna Kumalasari,&nbsp;Muhammad Irmawan,&nbsp;Retno Agnestisia","doi":"10.1002/aoc.70640","DOIUrl":"https://doi.org/10.1002/aoc.70640","url":null,"abstract":"<div>\u0000 \u0000 <p>This study investigated the synthesis, characterization, and performance of UiO-66-NH₂ and magnetic Fe₃O₄@Cellu@UiO-66-NH₂ composites as efficient supports for cellulase immobilization and reusability. UiO-66-NH₂ was synthesized using an amine-functionalized ligand (H₂BDC-NH₂) to enhance its enzyme adsorption capacity, whereas Fe₃O₄ nanoparticles were surface-modified with cellulose to facilitate the growth of UiO-66-NH₂ crystals, forming a magnetic composite. The materials were systematically characterized using XRD, FTIR, nitrogen adsorption–desorption isotherms with BET analysis, SEM–EDX, and TEM to evaluate their crystallinity, functional groups, surface area and porosity, morphology, and elemental composition. The high surface area and microporous structure of UiO-66-NH₂ (900.67 m²/g) made it suitable for enzyme immobilization, whereas the Fe₃O₄@Cellu@UiO-66-NH₂ composite offered additional advantages such as magnetic recoverability and improved pore accessibility. Both materials were employed for cellulase immobilization via physical adsorption, yielding enzyme loading capacities of 290.63 mg/g for UiO-66-NH₂ and 295.47 mg/g for the composite. Reusability tests showed that more than 68% of enzymatic activity was retained after 10 cycles, whereas storage stability tests indicated over 52% activity retention after 30 days at 4°C. These findings underscore the superior stability, reusability, and immobilization efficiency of UiO-66-NH₂-based composites, particularly Fe₃O₄@Cellu@UiO-66-NH₂, making them promising candidates for industrial biocatalysis and enzyme reuse applications.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148784181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ecological-Friendly LaS: PrS1.7: Gd2S3 Made From Dithiocarbamate Precursors: A Step Forward in High-Performance Supercapacitors Efficiency","authors":"Shaan Bibi Jaffri,&nbsp;Khuram Shahzad Ahmad,&nbsp;Jehad S. Al-Hawadi,&nbsp;Bhumikaben Makawana,&nbsp;Ram K. Gupta,&nbsp;Osama M. Alkhudhari,&nbsp;Suliman A. Alderhami,&nbsp;Amal Alruwaili,&nbsp;Mousa M. Hossin","doi":"10.1002/aoc.70639","DOIUrl":"https://doi.org/10.1002/aoc.70639","url":null,"abstract":"<div>\u0000 \u0000 <p>The growing need for effective and maintainable charge-storing devices for the production of environmentally sound electrode substances. In the present study, a chalcogenide semiconducting nanomaterial LaS: PrS_1.7: Gd₂S₃ has been produced by a single route using diethylthiocarbamate ligand. The prepared nanocomposite showed a 3.79 eV band gap and possesses extraordinary photoactive property owing to its strong light absorption. Crystallographic study via X-ray diffractometry analysis displayed numerous crystal phases with an average crystallite size of about 33.86 nm. Functional group analysis using infrared spectroscopic technique elucidates the existence of metal-sulfide linkages (LaS: PrS_1.7: Gd₂S₃) in the range of 521–977 cm⁻¹ of wavenumber. The surface topography of the prepared nanocomplex displayed unique morphology with multiple active sites to carry out electrochemical (redox) reactions. The electrochemical evaluation, employing a standard three-electrode system verified a specific capacitance of about 989.49 Fg⁻¹ and a power density of 10156.69 W kg⁻¹ and one of the electrochemical tests evaluated a low series resistance of 0.65 Ω. The calculated results indicate that the prepared material LaS: PrS_1.7: Gd₂S₃ is a good choice for energy storage devices such as next-generation supercapacitors.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148754119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zn-Assisted Evaporation-Pyrolysis Strategy to Prepare Tannic Acid-Derived Fe-Fe3C-Fe3O4@CN-l Catalyst for Selective Hydrogenation of Nitroarenes","authors":"Xuewei Li,&nbsp;Zeyu Sha,&nbsp;Yue Liu,&nbsp;Shoushan Yang,&nbsp;Rui Sun,&nbsp;Zirui Wang,&nbsp;Xuefeng Bai","doi":"10.1002/aoc.70638","DOIUrl":"https://doi.org/10.1002/aoc.70638","url":null,"abstract":"<div>\u0000 \u0000 <p>The selective hydrogenation of nitroarenes is an indispensable reaction for the production of high-value arylamines in fine chemical and pharmaceutical industries. However, it remains challenging to develop low-cost, high-efficiency, and durable non-noble metal catalysts for such reactions under mild conditions. In this contribution, a novel Fe-Fe₃C-Fe₃O₄ embedded in nitrogen-doped carbon (Fe-Fe₃C-Fe₃O₄@CN-l) was successfully prepared using biomass tannic acid as a sustainable precursor via a facile Zn-assisted evaporation-pyrolysis route. Structural analyses based on XRD, TEM, BET, Raman, and XPS confirm that the evaporation of Zn species during pyrolysis effectively regulates the Fe-based nanoparticles, improves metal dispersion, enriches carbon defects, increases specific surface area, and generates abundant Fe-N species. Using hydrazine hydrate as a green hydrogen donor, the optimized catalyst exhibits outstanding hydrogenation performance, achieving a nitrobenzene conversion of 98.5% and aniline selectivity above 99.8%. Moreover, the catalyst possesses excellent substrate adaptability toward various functionalized nitroarenes and prominent reusability without noticeable performance decay after five consecutive cycles. This work provides a facile, green, and universal strategy for the rational design and fabrication of high-performance biomass-derived non-noble metal catalysts for advanced hydrogenation applications.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148754118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ruthenium(II) Schiff Base Complexes With 9-Formyl-8-Hydroxyjulolidine: From Synthesis to Anticancer Insights","authors":"Jayakumar Megapriya,&nbsp;Periasamy Viswanathamurthi,&nbsp;Jebiti Haribabu,&nbsp;Jan Grzegorgz Malecki","doi":"10.1002/aoc.70632","DOIUrl":"https://doi.org/10.1002/aoc.70632","url":null,"abstract":"<div>\u0000 \u0000 <p>Two hydrazone-based Schiff base ligands were synthesized through condensation reaction between 9-formyl-8-hydroxyjulolidine and 2-hydrazinobenzothiazole or 2-hydrazinoquinoline. These ligands were subsequently coordinated to the precursor complex [RuHCl(CO)(EPh₃)₃] (E = P or As), yielding a new family of Ru(II) complexes with the general formula [RuH(CO)(EPh₃)₂L] (<b>C1–C4</b>) (E = P or As; L = 9-formyl-8-hydroxy-julolidine-derived hydrazone ligands). Micro analyses and many spectroscopic methods, such as FT-IR, UV–Vis, NMR spectroscopy, and electrospray ionization (ESI) mass spectrometry, were used to conform the formation of ligands and their associated Ru(II) complexes. Solid-state structure analysis of complexes (<b>C1</b> and <b>C3</b>) confirmed distorted octahedral coordination geometries around the Ru(II) center. To assess the biological potential relevance of the newly synthesized complexes, molecular docking studies were first performed, which revealed favorable binding interactions with the selected target proteins. Additionally, intermolecular interactions in the crystalline state were investigated using Hirshfeld surface analysis and two-dimensional fingerprint plots, which revealed H···H contacts as the main contribution. The in vitro antiproliferative properties of the Ru(II) complexes were assessed against a noncancerous cell line (MCF-10A) and two cancer cell lines (MCF-7 and HepG-2). The results demonstrated pronounced anticancer activity relative to <i>cis</i>platin, with complex <b>C2</b> exhibiting exceptional cytotoxicity toward HepG-2 cells. Furthermore, flow cytometry study revealed that treatment with complex <b>C3</b> predominantly induced late apoptosis in HepG-2 cells, whereas complex <b>C2</b> primarily triggered early apoptotic cell death.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148753902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-Pot Random Copolymerization of Lactide and ε-Caprolactone Mediated by a Tri-Coordinated Zinc Catalyst","authors":"Priyanku Nath,&nbsp;Shweta Sagar,&nbsp;Aranya Ray,&nbsp;Himadri Karmakar,&nbsp;Rohan Kumar Mehar,&nbsp;Alok Sarkar,&nbsp;Tarun K. Panda","doi":"10.1002/aoc.70635","DOIUrl":"https://doi.org/10.1002/aoc.70635","url":null,"abstract":"<div>\u0000 \u0000 <p>A zinc complex bearing imino-phosphanamidinate chalcogenide ligands efficiently promotes the ring-opening polymerization (ROP) of <i>rac</i>-lactide (<i>rac</i>-LA) and ε-caprolactone (ε-CL), as well as their copolymerization. The complex demonstrated good control over the ROP of <i>rac</i>-LA, affording isotactic poly (lactic acid) (PLA) with high stereoselectivity (<i>P</i>_m = 0.82) and narrow dispersity (Ð &lt; 1.3). One-pot ring-opening copolymerization (ROCOP) of <i>rac</i>-LA and ε-CL in the presence of the zinc complex has been shown to produce random copolymers with predictable molecular weights. The fact that the randomization of the copolymers is driven concurrently by the formation of a gradient/partially random copolymer species and slow transesterification was established via in situ NMR spectroscopy. PLA-<i>co</i>-CL copolymers with varying CL/LA ratios were synthesized, displaying a single glass transition temperature (<i>T</i>_<i>g</i>) within the range between the <i>T</i>_<i>g</i> values of the corresponding homopolymers.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148753166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recyclable Magnetic Cu-MOF-74-Catalyzed C–N Coupling and Cyclization for Synthesis of Azole- and Indole-Fused Quinazolines or Pyrimidines","authors":"Thu Thuy Dinh,&nbsp;Thanh Ngoc Truong,&nbsp;Van Du Cao,&nbsp;Do Minh Hoang Vo,&nbsp;Pham Duy Quang Dao","doi":"10.1002/aoc.70636","DOIUrl":"https://doi.org/10.1002/aoc.70636","url":null,"abstract":"<div>\u0000 \u0000 <p>An improved methodology for synthesis of benzimidazole-fused quinazolines and pyrimidines was developed by recyclable magnetic Cu-MOF-74-catalyzed nucleophilic aromatic/vinylic substitution and cyclization of 2-(2-bromoaryl/vinyl)azoles and indoles with 2-aminoazoles. The reaction could apply to a wide scope of starting materials containing electron-donating or -withdrawing substituents on bromophenyl and azole/indole moieties. The catalyst could be recovered and reused up to four times without significant loss of catalytic activity.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"40 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148752792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}