Applied Organometallic Chemistry最新文献_第3页

Synthesis of a New Bis-4-Cumyl Phenoxy Phthalocyaninato Silicon (IV) and Its Evaluation on Selectivity for Iron (III) Ions 一种新的双-4-异丙基苯氧基酞菁硅 (IV) 的合成及其对铁 (III) 离子选择性的评估

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-16 DOI: 10.1002/aoc.70120

Mehmet Salih Ağırtaş, Derya Güngördü Solğun

{"title":"Synthesis of a New Bis-4-Cumyl Phenoxy Phthalocyaninato Silicon (IV) and Its Evaluation on Selectivity for Iron (III) Ions","authors":"Mehmet Salih Ağırtaş, Derya Güngördü Solğun","doi":"10.1002/aoc.70120","DOIUrl":"https://doi.org/10.1002/aoc.70120","url":null,"abstract":"<div>\u0000 \u0000 Axial phthalocyanine compound carrying 4-cumyl phenoxy groups was obtained from the reaction of 4-cumyl phenol with silicon phthalocyanine dichloride (SiPcCl2). The compound was characterized by 1H NMR, UV–visible light, FTIR, and mass spectrum. Electronic properties and photochemical properties of the compound were investigated by UV–visible light spectra. Singlet oxygen production capacity for the compound was investigated, and the singlet oxygen production (Φ∆) value was found to be 0.14. The sensor potential of the compound was investigated by UV–visible light spectra against magnesium (II) ions (Mg2+), manganese (II) ions (Mn2+), sodium (I) ions (Na+), nickel (II) ions (Ni2+), zinc (II) ions (Zn2+), silver (I) ions (Ag+), barium (II) ions (Ba2+), cadmium (II) ions (Cd2+), copper (II) ions (Cu2+), cobalt (II) ions (Co2+), and iron (III) ions (Fe3+). The selective sensitivity of the phthalocyanine compound only to Fe3+ ions enables the practical analysis of Fe3+ ions in many environments. This study presents an alternative and practically applicable method for the sensitive determination of Fe3+ ions, which have widespread adverse effects on the environment, ecosystem and human health.\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparation, Chemical Characterization, and Determination of the Cytotoxicity and Anti-Thyroid Cancer Properties of Pomegranate Aqueous Extract Green-Synthesized Silver Nanoparticles Following the STAT3 and p53 Signaling Pathways

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-16 DOI: 10.1002/aoc.70112

Mengxuan Mao, Zhanbin Cui, Xiaofei Wei, Tengfei Liu, Mingqiang Han

{"title":"Preparation, Chemical Characterization, and Determination of the Cytotoxicity and Anti-Thyroid Cancer Properties of Pomegranate Aqueous Extract Green-Synthesized Silver Nanoparticles Following the STAT3 and p53 Signaling Pathways","authors":"Mengxuan Mao, Zhanbin Cui, Xiaofei Wei, Tengfei Liu, Mingqiang Han","doi":"10.1002/aoc.70112","DOIUrl":"https://doi.org/10.1002/aoc.70112","url":null,"abstract":"<div>\u0000 \u0000 The biogenic silver nanoparticles manufactured using pomegranate as a supporting material are described in this study. The plant's leaves effectively stabilized the produced silver nanoparticles (Ag NPs) and acted as a natural reducing agent. The physicochemical characteristics of the prepared NPs were examined using TEM, EDX, FE-SEM, and UV–Vis methods. According to the study's data, the antioxidant properties of nanoparticles may be related to how well they treat thyroid cancer in humans. The capacity of biologically produced nanoparticles to prevent thyroid cancer cells was assessed. As determined by the MTT assay, the silver nanoparticles had strong anti-thyroid cancer characteristics, effectively eliminating the BCPAP cancer cell in a way that depended on both concentration and time. Ag NPs decrease the anti-apoptotic marker Bcl-2 level while promoting cell death, which is associated with increased levels of pro-apoptotic indicators such as cleaved caspase-8 and Bax. Additionally, compared to the corresponding control group, silver nanoparticles show a reduction in colony development. The data of Ag NPs showed that p53 expression was much higher, and that the examined cell lines had lower levels of signal transducer and activator of transcription 3 (STAT3). This implies that the pomegranate extract-induced biological reactions in BCPAP human thyroid cancer cells depend critically on STAT3 and p53.\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Triphenylamine-Based Dual Chemosensor for Cu2+ and Co2+ Ions and Volatile Acid Vapour Sensor, DFT Calculations 基于三苯胺的 Cu2+ 和 Co2+ 离子双重化学传感器和挥发性酸蒸汽传感器，DFT 计算

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-16 DOI: 10.1002/aoc.70105

Aravind R. Nesaragi, Jyoti Nagalik, Mounesh, Sharanakumar T. M., Halligudra Guddappa, Tahani Mazyad Almutairi, Sanjeev R. Inamdar, Anup Pandith

{"title":"Triphenylamine-Based Dual Chemosensor for Cu2+ and Co2+ Ions and Volatile Acid Vapour Sensor, DFT Calculations","authors":"Aravind R. Nesaragi, Jyoti Nagalik,  Mounesh, Sharanakumar T. M., Halligudra Guddappa, Tahani Mazyad Almutairi, Sanjeev R. Inamdar, Anup Pandith","doi":"10.1002/aoc.70105","DOIUrl":"https://doi.org/10.1002/aoc.70105","url":null,"abstract":"<div>\u0000 \u0000 In this work, a novel fluorescent chemosensor 3-(2-(2-(4-(diphenylamino)phenyl)-4,5-diphenyl-1H-imidazol-1-yl)thiazol-4-yl)-2H-chromen-2-one (TCCM) was effectively synthesized and characterized through NMR and Mass spectrum. An approach towards the recognition of Cu2+ and Co2+ ions using a turn-off fluorescence technique was developed. The chemosensor TCCM also exhibited colorimetric and fluorometric sensing behaviour with a visible colorimetric response to trifluoroacetic acid (TFA). Upon the addition of TFA to TCCM, a new peak formation at 500 nm in the absorption spectra along with the visible colour change from colourless to brown. In addition, it exhibits high selectivity towards Cu2+ and Co2+ ions with a limit of detection of 4.2 and 3.9 μM, respectively. It was discovered that the sensor was quite selective for Cu2+ and Co2+ ions that had a lot of competing ions. Further, the studies were supported by DFT analysis and NBO studies.\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive Exploration of Water-Soluble Schiff Base Complexes of Ni (II), Cu (II), Mn (II), and Ce (III): Electrochemical, Computational, and Biological Studies

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-16 DOI: 10.1002/aoc.70122

Eida S. Al-Farraj, Mahdi A. Mohammed

{"title":"Comprehensive Exploration of Water-Soluble Schiff Base Complexes of Ni (II), Cu (II), Mn (II), and Ce (III): Electrochemical, Computational, and Biological Studies","authors":"Eida S. Al-Farraj, Mahdi A. Mohammed","doi":"10.1002/aoc.70122","DOIUrl":"https://doi.org/10.1002/aoc.70122","url":null,"abstract":"<div>\u0000 \u0000 Novel water-soluble Ni(II), Cu(II), Mn(II), and Ce(III) complexes of sodium 4-hydroxy-3-((2-picolinoylhydrazineylidene)methyl)benzenesulfonate ligand (NaH2PH) were synthesized and characterized by the different analytical methods and spectroscopic techniques as well as magnetic measurements. The chemical structures of the studied chelates were supported by computational studies using DFT calculation. The ligand acts as a mono-negative tridentate (ONN) ligand in the copper (II) complex by (C=N)py, (C=N)az, and the deprotonated enolic oxygen atom (C-O). In [Mn2(NaPH)Cl2(H2O)2] complex, NaH2PH ligand acts as a bi-negative tetradentate (ONNO) ligand via deprotonated (OH)phenolic and (C=N*) groups around the first Mn (II), the (HO)enolic, and (C=N)az groups coordinated to another Mn(II). As a mono-negative bidentate (ON) ligand, the NaH2PH ligand functions in the [Ni(NaHPH)Cl(H2O)]·3H2O complex. The ligand functions as a bi-negative tetradentate (ONNO) ligand in the [Ce(NaPH)Cl(H2O)]·3H2O complex. The isotropic shape of the ESR spectrum of [Cu(NaHPH)(H2O)2Cl].H2O complex confirmed the octahedral geometry around the copper(II) ion. The voltammogram of the Cu(II) and Mn(II) ions exhibited two oxidation and two reduction waves. The antiradical potencies discovered have good radical scavenging activities against ABTS and DPPH radicals. Antimicrobial activities of the isolated complexes have been assessed against selected microorganism. According to the molecular docking studies, the Mn(II) complex shows higher interaction against MCF-7 (PDB ID: 3W2S), which has a good agreement with experimental data.\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adsorptive Removal of Congo Red Dye From Aqueous Media Using Composite of Graphitic Carbon Nitride Nanosheet and the Biopolymer Alginate

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-16 DOI: 10.1002/aoc.70059

Mohammad Ali Shirani, Mohammad Dinari, Mohammad Hassan Maleki, Monir Fouladi

{"title":"Adsorptive Removal of Congo Red Dye From Aqueous Media Using Composite of Graphitic Carbon Nitride Nanosheet and the Biopolymer Alginate","authors":"Mohammad Ali Shirani, Mohammad Dinari, Mohammad Hassan Maleki, Monir Fouladi","doi":"10.1002/aoc.70059","DOIUrl":"https://doi.org/10.1002/aoc.70059","url":null,"abstract":"<div>\u0000 \u0000 The removal of dyes from wastewater using stable adsorbents is well documented in numerous scientific reports. Therefore, this study aimed to evaluate a composite of graphitic carbon nitride nanosheet (g-C3N4NS) and the biopolymer alginate for the removal of Congo red (CR) dye from aqueous media. To address the challenges associated with the independent use of calcium alginate and g-C3N4NS in water, particularly regarding recovery issues, silica-coated magnetic nanoparticles (SMNPs) were incorporated into the composite. To achieve this objective, an alginate-based bioadsorbent was synthesized by crosslinking sodium alginate with calcium chloride in the presence of g-C3N4NS and SMNPs using an in situ method. Structural characterization was conducted using BET, TGA, TEM, FE-SEM, and EDX-Mapping analyses. Subsequently, the bioadsorbent was utilized to remove CR dye. The influence of various parameters, including initial concentration, contact time, adsorbent dosage, and pH, was subsequently investigated. According to the isotherm models, the linear Langmuir model exhibited a good fit to the experimental data for CR, indicating a maximum adsorption capacity of 68.03 mg g−1 at pH 5 within 120 min. The synthesized composite has the potential to pave the way for novel applications in both organic and inorganic transformations, as well as in the physical or chemical remediation of diverse pollutants.\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green Synthesis of Persimmon Tannin Modified With CoFe2O4@SiO2 Nanoparticles for Au(III) Ions Adsorbent: Synthesis Optimization and Characterization

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-13 DOI: 10.1002/aoc.70118

Jolang Budiarta, Dinar Indah Lufita Sari, Ratna Betriani, Leny Yuliatun, Eko Sri Kunarti, Roto Roto

{"title":"Green Synthesis of Persimmon Tannin Modified With CoFe2O4@SiO2 Nanoparticles for Au(III) Ions Adsorbent: Synthesis Optimization and Characterization","authors":"Jolang Budiarta, Dinar Indah Lufita Sari, Ratna Betriani, Leny Yuliatun, Eko Sri Kunarti, Roto Roto","doi":"10.1002/aoc.70118","DOIUrl":"https://doi.org/10.1002/aoc.70118","url":null,"abstract":"<div>\u0000 \u0000 Persimmon tannin (PT) was immobilized onto CoFe2O4@SiO2 microspheres to create a novel core–shell nanostructured magnetic bioadsorbent. The as-designed CoFe2O4@SiO2@PT was used to recover Au(III) ions. The bioadsorbent synthesis was performed with different reaction times of 2, 4, 6, 12, and 24 h with a PT to magnetic core weight ratio of 0.8, 1.0, 1.2, 1.5, and 2.0. The profile of Au(III) adsorption by the material in aqueous medium was investigated in a batch system. XRD, FTIR, TEM, thermal analysis, and VSM were used to analyze the materials. The adsorption experiments were conducted in a pH 5 medium, with an adsorbent weight of 5.0 mg and an Au(III) ion concentration of 200 mg/L. The XRD shows that the material is crystalline and retains its structure during the modification. The FTIR data suggest that the material contained expected functional groups. As indicated by the VSM data, it maintains magnetic properties with a range of 12.76 to 17.45 emu/g. The Au(III) adsorption mechanism by the CoFe2O4@SiO2@PT adsorbent was realized by electrostatic interaction and complex formation followed by the reduction of the ions. The maximum Au(III) adsorption capacity was recorded to be 393.34 mg/g.\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green Synthesis and Characterization of ZnO/α-Fe2O3 Nanocomposites Using Hydrocotyle umbellata Leaf Extract and Evaluation of Their Antimicrobial Properties

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-13 DOI: 10.1002/aoc.70121

Raja Kaliyaperumal, Karuppiah Nagaraj, Karunganathan Sakthikumar, Mohammed F. Albeshr, Gunasekaran Velmurugan

{"title":"Green Synthesis and Characterization of ZnO/α-Fe2O3 Nanocomposites Using Hydrocotyle umbellata Leaf Extract and Evaluation of Their Antimicrobial Properties","authors":"Raja Kaliyaperumal, Karuppiah Nagaraj, Karunganathan Sakthikumar, Mohammed F. Albeshr, Gunasekaran Velmurugan","doi":"10.1002/aoc.70121","DOIUrl":"https://doi.org/10.1002/aoc.70121","url":null,"abstract":"<div>\u0000 \u0000 In this study, ZnO/α-Fe2O3 nanocomposites were synthesized via a green coprecipitation method using Hydrocotyle umbellata leaf extract as a reducing and stabilizing agent. The synthesis involved Zn (NO₃)₂.6H₂O, ferric chloride, and sodium hydroxide in various molar ratios of ZnO/α-Fe₂O₃ (9:1, 8:2, 7:3), followed by calcination at 400°C. The synthesized nanocomposites were analyzed using XRD, FTIR, UV-Vis, and SEM to determine their crystalline structure, functional groups, optical properties, and surface morphology. The XRD analysis confirmed the formation of ZnO and α-Fe₂O₃ phases, whereas FTIR confirmed the presence of metal-oxygen bonds and phenolic compounds from the plant extract. UV-vis analysis showed a redshift in the absorption spectra, indicating a reduction in bandgap energy in ZnO/α-Fe₂O₃ nanocomposites compared to pure ZnO. The SEM results confirmed that the ZnO/α-Fe2O3 composites exhibit excellent crystallinity, with an average crystal size of approximately 39 nm, calculated using the Debye–Scherrer equation. The antimicrobial activity of ZnO/α-Fe₂O₃ nanocomposites was evaluated using the disk diffusion method against Staphylococcus aureus, Escherichia coli, and Aspergillus niger. The ZnO/α-Fe₂O₃ (8:2) formulation showed the strongest antibacterial effect against S. aureus, highlighting its potential for eco-friendly antimicrobial applications.\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, Spectroscopic Characterization, DFT Calculations, and Molecular Docking of Novel Thiourea Complexes and Their Cytotoxic and Antimicrobial Activities

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-12 DOI: 10.1002/aoc.70125

Mahmoud M. Ahmed, Nour T. I. Salama, Samir Bondock, Amina A. Soayed, Rehab M. I. Elsamra

{"title":"Synthesis, Spectroscopic Characterization, DFT Calculations, and Molecular Docking of Novel Thiourea Complexes and Their Cytotoxic and Antimicrobial Activities","authors":"Mahmoud M. Ahmed, Nour T. I. Salama, Samir Bondock, Amina A. Soayed, Rehab M. I. Elsamra","doi":"10.1002/aoc.70125","DOIUrl":"https://doi.org/10.1002/aoc.70125","url":null,"abstract":"<div>\u0000 \u0000 This research presents the synthesis and comprehensive characterization of two novel bioactive thiourea derivatives (TU1 and TU2) and their complexes with Pd(II), Cd(II), Cu(II), and Ni(II) salts. The ligands effectively formed stable chelates with the metal ions, displaying specific 1:1 and 1:2 stoichiometric ratios. Reduction of Cu(II) by thiourea was approved by the diamagnetic behavior of the yielded Cu(I)-TU complexes. Thermal analysis indicated that the complexes possess significant thermal stability. Computational studies provided detailed insights into the electronic properties, such as energy gaps and dipole moments, which correlate with the observed chemical reactivity and the cell membrane permeability to the complexes. Notably, the Cd(II)-TU2 complex demonstrated significant in vitro anticancer activity with IC50 values of 17.8 ± 0.6 μM and 12.0 ± 0.3 μM against MCF-7 and HepG-2 cell lines, respectively. This complex displayed slightly superior activity compared to cisplatin and nearly threefold the efficacy of imatinib. The superior activity of Cd(II)-TU2 complex could be due to the existence of many electron-rich sites in the 1,4-benzodioxane moiety and less bulky acetamide substituent of TU2 ligand. The data suggest that the synthesized compounds, especially the Cd(II)-TU2 complex and the TU2 ligand, are promising candidates for further investigation in therapeutic applications, particularly in the development of anticancer agents.\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, Characterization, Molecular Docking, and In Vitro Biological Activities of Schiff Base Metal Complexes With Furan Moiety

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-12 DOI: 10.1002/aoc.70116

Saira Nayab, Kalsoom Jan, Waliullha Khan, Amjad Subhan, Nhi Thi Xuan Nguyen, Younghu Son, Minyoung Yoon, Hyosun Lee

{"title":"Synthesis, Characterization, Molecular Docking, and In Vitro Biological Activities of Schiff Base Metal Complexes With Furan Moiety","authors":"Saira Nayab, Kalsoom Jan, Waliullha Khan, Amjad Subhan, Nhi Thi Xuan Nguyen, Younghu Son, Minyoung Yoon, Hyosun Lee","doi":"10.1002/aoc.70116","DOIUrl":"https://doi.org/10.1002/aoc.70116","url":null,"abstract":"<div>\u0000 \u0000 Herein, Cu(II), Zn(II), and Cd(II) complexes with furan-derived Schiff base ligand, (E)-N1,N1-diethyl-N2-(furan-2-ylmethylene)ethane-1,2-diamine(DEF), were synthesized. The synthesized ligand and M(II) (M = Cu, Zn, and Cd) complexes were characterized to confirm their purity and successful synthesis using 1H NMR, 13C NMR, and FTIR spectroscopy. Thermal analysis demonstrated their stability, whereas UV-Vis spectroscopy and molar conductance studies provided insights into their electronic properties and coordination behavior. Additionally, X-ray diffraction studies indicated that the Zn(II) and Cd(II) complexes have distorted tetrahedral geometries, whereas the Cu(II) complex adopted distorted square planar geometry. The studied complexes showed remarkable free-radical scavenging activity. Furthermore, they exhibited good inhibitory activity against urease and α-amylose. In particular, [Cu(DEF)Cl2] showed the best antioxidant activity, with an IC50 of 3.21 ± 0.19 μM, and the highest α-amylose inhibitory activities, with an IC50 of 6.11 ± 0.33 μM. Moreover, [Cd(DEF)Br2] proved to be more potent against Jack bean and Bacillus pasteurii ureases, with IC50 values of 3.90 ± 0.11 μM and 6.01 ± 0.10 μM, respectively. Molecular docking studies showed a good correlation between the biological activities of the synthesized [M(DEF)X2] complexes. Thus, the proposed compounds can serve as promising candidates for the treatment of infectious diseases.\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Palladium (II) Catalyzed Synthesis of Meta-Substituted Biphenyls via Carboxylate Directed Ortho-Arylation Decarboxylation Cascade: Experimental and Theoretical Insights

IF 3.7 2区化学

Applied Organometallic Chemistry Pub Date : 2025-03-11 DOI: 10.1002/aoc.70066

Debasish Sarmah, Porag Bora, Ankur Kanti Guha, Nand Kishor Gour, Anup Choudhury, Utpal Bora

引用次数: 0