Applied Organometallic Chemistry最新文献

{"title":"Ultrasound-Assisted Dispersion of Metal Nanoparticles on Clay for Reduction of Organic Pollutants and Antimicrobial Activities","authors":"Mohammed Hachemaoui,&nbsp;Bouhadjar Boukoussa,&nbsp;Adel Mokhtar,&nbsp;Fadila Benali,&nbsp;Carmen B. Molina,&nbsp;Kheira Chinoune,&nbsp;Fatima Zohra Zeggai,&nbsp;Adel Kessouri,&nbsp;Shashikant P. Patol,&nbsp;Jibran Iqbal,&nbsp;Issam Ismail,&nbsp;Mohamed Abboud","doi":"10.1002/aoc.70191","DOIUrl":"https://doi.org/10.1002/aoc.70191","url":null,"abstract":"<div>\u0000 \u0000 <p>Water pollution by persistent dyes and bacteria has become one of the major environmental concerns. One of the most widely used strategies is the use of supported metal nanoparticles (MNPs) to remove a wide variety of dyes. This work concerns the dispersion of MNPs (M = Ag, Zn, and Cu) on kaolin clay using ultrasonic irradiation. The resulting solids were used as catalysts to reduce methylene blue (MB), methyl orange (MO), and orange G (OG) dyes in a simple and binary system. The obtained results showed that ultrasonic irradiation produced a good dispersion of MNPs with ultrafine sizes. According to XPS and TEM analysis, the MNPs (M = Ag, Cu, and Zn) were well formed. Catalytic tests showed that AgNPs-modified kaolin (K-Ag) was the most efficient compared with other catalysts modified by ZnNPs and CuNPs. In all tests, the K-Ag catalyst was more efficient with MB dye than with azo dyes. It was shown that the reduction of dyes is influenced by the concentration of the starting reactants, the mass of the catalyst, and the nature of the dye used. The rate constants were calculated to be 83.10⁻⁴ and 24.10⁻⁴ s⁻¹ for MB and MO dyes, respectively. For the system containing a mixture of dyes, the K-Ag catalyst was more selective with MB dye. The reuse of the K-Ag catalyst showed good results without losing its performance. Antibacterial applications showed that K-Cu material was the most efficient overall bacteria.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143925972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facile Synthesis and Characterization of Trimetallic CuCrFe-BTC MOF for the Adsorptive Removal of Diamond Green G: Kinetic, Isotherm, and Thermodynamic Study","authors":"Ali Umar,&nbsp;Sultan Alam,&nbsp;Hira Zaman,&nbsp;Muhammad Zahoor,&nbsp;Riaz Ullah,&nbsp;Essam A. Ali,&nbsp;Muhammad Naveed Umar","doi":"10.1002/aoc.70189","DOIUrl":"https://doi.org/10.1002/aoc.70189","url":null,"abstract":"<div>\u0000 \u0000 <p>In this study, trimetallic organic frameworks (CuCrFe-BTC MOF) was synthesized via the solvothermal method and applied for the adsorptive removal of diamond green G dye from aqueous medium. The synthesized CuCrFe-BTC MOF was characterized by SEM, FTIR, XRD, TGA, Zeta potential analyzer, and surface area analyzer. The results revealed that the synthesized MOF has spherical particles in the nanoscale range (80 nm), FTIR analysis confirmed the presence of necessary functional groups, XRD indicated high crystallinity with distinct peaks and TGA analysis demonstrated the thermal stability up to 500°C. The moderate negative charge value (−14.7 mV) as predicted by zeta potential analysis suggests its suitability for remediation of cationic pollutants. BET analysis revealed a high surface area of 767 m²/g, with a microporous structure. The synthesized MOF were then employed for the removal of diamond green G dye from water using batch adsorption approach. The effect of contact time, adsorbent dosage, pH, initial dye concentration, and temperature on adsorption was also evaluated to optimize the adsorption process. The maximum adsorption was achieved at optimum contact time of 60 min, adsorbent dosage of 0.01 g, pH 8, initial dye concentration of 100 ppm, and temperature 298 K. Different isotherm and kinetic models were applied to the adsorption experimental data. Kinetic data analysis revealed the best fit of the data with pseudo-second-order model confirming the chemisorption nature of the adsorption process. The isotherm studies data fitted well into Langmuir isotherm model, indicating monolayer adsorption with a maximum adsorption capacity <i>Q</i>_<i>m</i> of 434 mg.g⁻¹. Thermodynamic studies revealed that the adsorption process was endothermic with an enthalpy change ∆H° of 14.74 kjmol⁻¹ and an entropy change ∆S° of 53.44 jmol⁻¹ K⁻¹. Gibbs free energy ∆G° was negative at all tested experimental temperatures. The Gibbs free energy value increased with increase in temperature (−0.921, −1.989, and −3.058 at 293, 313, and 333 K respectively) indicated the feasibility of the process at high temperature. The overall adsorption process might involve several potential mechanisms including chemisorption involving π-π bonding, pore-filling, electrostatic interactions, and hydrogen bonding. The adsorbent was regenerated with sodium hydroxide and ethanol for many cycles and very little differences in adsorption capacity were recorded till 7th cycle. The study verified the structural stability and performance of CuCrFe-BTC MOF and showed its regeneration potential in industrial applications and could therefore, be considered as best alternative of commercial activated carbon.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phosphine-Modified [FeFe]-Hydrogenase Mimics With Various –S(CH2)nS– Linker Lengths (n = 4, 5, 7, 8): Impact of PPh3 Ligand on Structure, Redox Properties, and Catalytic Activity","authors":"Hassan Abul-Futouh,&nbsp;Sara J. Abaalkhail,&nbsp;Khalid A. Alrashidi,&nbsp;Abdulaziz A. Alayyafi,&nbsp;Zaher A. Algharaibeh,&nbsp;Adnan S. Abu-Surrah,&nbsp;Hajem Bataineh,&nbsp;Helmar Görls,&nbsp;Wolfgang Weigand","doi":"10.1002/aoc.70199","DOIUrl":"https://doi.org/10.1002/aoc.70199","url":null,"abstract":"<div>\u0000 \u0000 <p>In this study, we synthesized a series of PPh₃-substituted diiron complexes with the general formula [Fe₂(CO)₅PPh₃{<i>μ</i>-S(CH₂)_<i>n</i>S}] (<i>n</i> = 4 (<b>1</b>), 5 (<b>2</b>), 7 (<b>3</b>), 8 (<b>4</b>)), bearing structural similarities to the active site of [FeFe]-hydrogenase. These complexes were derived from their parent analogues, [Fe₂(CO)₆{<i>μ</i>-S(CH₂)_<i>n</i>S}] (<i>n</i> = 4, 5, 7, 8), through ligand substitution. Their formation was verified through a combination of spectroscopic methods, elemental analysis, and X-ray crystallography, confirming their structural integrity and composition. Moreover, we examined how the PPh₃ ligand and the varying lengths of the dithiolato linker in complexes <b>1</b>–<b>4</b> affect their redox properties and catalytic performance. Using cyclic voltammetry, we evaluated their electrochemical behavior and proton reduction activity in the presence of acetic acid (AcOH). Consequently, the reduction potential shifts of complexes <b>1</b>–<b>4</b>, in comparison to their precursors, followed the sequence: <b>3</b> &gt; <b>2</b> &gt; <b>1</b> &gt; <b>4</b>. Furthermore, at the highest AcOH concentration established, complex <b>3</b> demonstrates the most significant current enhancement (<i>i</i>_cat/<i>i</i>_p = 26.2). In comparison, complexes <b>1</b>, <b>2</b>, and <b>4</b> exhibit relatively similar <i>i</i>_cat/<i>i</i>_p values of 13.6, 13.0, and 11.9, respectively.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co2+ and Ni2+ Complexes of the New (E)-N′-(2-hydroxy-5-nitrobenzylidene) morpholine-4-carbothiohydrazide Chelating Agent: Synthesis, Spectral, Thermal, and Corrosion Inhibition Investigations","authors":"Amal A. Nassar","doi":"10.1002/aoc.70179","DOIUrl":"https://doi.org/10.1002/aoc.70179","url":null,"abstract":"<div>\u0000 \u0000 <p>In the current study, the new (<i>E</i>)-<i>N′</i>-(2-hydroxy-5-nitrobenzylidene)morpholine-4-carbothiohydrazide (<b>H</b>_<b>2</b><b>L</b>) ligand and its [Co(HL)₂] (<b>1</b>) and [Ni(HL)Cl]·1.5H₂O (<b>2</b>) complexes have been produced and analyzed using analytical and spectral tools as elemental microanalyses, conductivity measurements, ¹H- and ¹³C-NMR, FT-IR, UV–vis, XRD, SEM, and thermogravimetric and differential thermogravimetric (TG-DTG) analyses. The FT-IR vibrational data indicated that the ligand loses its phenolic proton and acts as a monobasic ONS tridentate anion in both of the complexes. UV–vis measurements, as well as magnetic data, proposed that the Co²⁺ complex (<b>1</b>) has octahedral geometry, whereas the Ni²⁺ complex (<b>2</b>) exists in a tetrahedral shape. Powder XRD patterns for the investigated compounds show that the ligand and its tetra-coordinated Ni²⁺ complex (<b>2</b>) have a crystalline nature with crystallite sizes of 96.68 and 170.29 nm, respectively, whereas, hexa-coordinated Co²⁺ complex (<b>1</b>) is amorphous. Furthermore, the thermal pyrolysis of the organic ligand and its metal chelates were presented. Also, the Coats–Redfern and Horowitz–Metzger models were employed to estimate the activation thermodynamic parameters for different pyrolytic stages of the two complexes. Furthermore, the efficacy of the (<b>H</b>_<b>2</b><b>L</b>) ligand and its cobalt and nickel complexes as inhibitors of corrosion for carbon steel in 0.5 M H₂SO₄ solutions was examined through electrochemical (PDP and EIS) and theoretical (MC simulations and DFT) analyses. The information gathered from the PDP analysis demonstrated that the (<b>H</b>_<b>2</b><b>L</b>) ligand and its Co²⁺ and Ni²⁺ complexes function as mixed-type inhibitors. Additionally, findings from EIS studies confirm the development of a protective coating over carbon steel, thereby offering a shield against corrosion. The conclusions of both studies corroborate the effectiveness of the organic (<b>H</b>_<b>2</b><b>L</b>) and its Co²⁺ and Ni²⁺ complexes as corrosion inhibitors.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vitro Anticancer and Antibacterial Activity of a New Hg(II) Pyridinedicarboxylate Coordination Supramolecular Compound","authors":"Elham Akhtari,&nbsp;Khosro Mohammadi,&nbsp;Payam Hayati,&nbsp;Saeide Keshavarzi,&nbsp;Omid Tavallaei,&nbsp;Hossein Derakhshankhah,&nbsp;Heshmat Karamveysi,&nbsp;Mahnaz Mohammadpour,&nbsp;Pascal Retailleau","doi":"10.1002/aoc.70173","DOIUrl":"https://doi.org/10.1002/aoc.70173","url":null,"abstract":"<div>\u0000 \u0000 <p>Nanoparticles and single crystals of mercury(II) coordination supramolecular compounds, [HL′][Hg(L)(Cl)(H₂O)], (where H₂L = pyridine-2,6-dicarboxylic acid and L′ = 2,4-diamino-6-chloropyrimidine), have been synthesized using both the branch tube (1) and ultrasonic irradiation (UI) (1′) methods. The compounds were characterized using SEM, XRPD, FTIR spectroscopy, and elemental analysis through the EDS method. Single crystal X-ray diffraction (SCXRD) data for compound (1) indicates that the Hg²⁺ ion has a coordination number of five. The thermal stability of both macro (1) and nano-structures (1′) was investigated using thermal gravimetric analysis (TG). The antimicrobial properties of the Hg compound were evaluated against both gram-negative and gram-positive bacteria using the disk diffusion method. <i>Staphylococcus aureus</i> (IZD = 13 mm) was identified as the more susceptible bacterium after treatment compared to <i>Pseudomonas aeruginosa</i> (IZD = 10 mm) at a concentration of 31.25 μg/μL. In vitro cytotoxicity of the compound was screened against two cancer cell lines: human breast cancer (MCF7) and human prostatic adenocarcinoma (PC3). The results showed antiproliferative activity, with IC50 values of 15.83 μM for PC3 and 22.50 μM for MCF7. Finally, antioxidant activity testing revealed that the Hg(II) compound possesses relatively poor radical scavenging properties.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel 3D Heteronuclear (Cu(II) and Mg(II)) Coordination Polymer: Synthesis, Crystal Structure, and Catalytic Activity in the Formation of 1,2,3-Triazoles","authors":"Arefeh Ahadi,&nbsp;Mojtaba Amini,&nbsp;Mahdieh Ghobadifard,&nbsp;Sajjad Mohebbi,&nbsp;Jan Janczak","doi":"10.1002/aoc.70175","DOIUrl":"https://doi.org/10.1002/aoc.70175","url":null,"abstract":"<div>\u0000 \u0000 <p>In the current study, the heteronuclear coordination polymer C₁₂H₁₈Cu₂MgO₁₂ was synthesized in crystalline form using the gradual evaporation method and utilized as a precursor for the synthesis of CuO/MgO mixed nano-oxide. The crystal structure and thermal stability of the polymer were confirmed. Following the calcination of the polymer compound at 500°C, CuO/MgO mixed nano-oxide were synthesized. The morphology and structure of the nanopowders were characterized through FE-SEM, EDX, XRD, FT-IR, VSM, XPS, ICP-OES, and TEM techniques. Ultimately, the nanopowders were employed as catalysts in the azide–alkyne cycloaddition reaction. With very low leaching of copper (2.40 ppm) and magnesium ions (0.52 ppm), CuO/MgO nanocatalyst recycling and reuse were achieved for up to five cycles.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143919623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bimetallic Metal–Organic Framework (MOF)–Derived NiO/CuO-Embedded Carbon for Supercapacitor","authors":"Hani Nasser Abdelhamid","doi":"10.1002/aoc.70193","DOIUrl":"https://doi.org/10.1002/aoc.70193","url":null,"abstract":"<div>\u0000 \u0000 <p>Metal–organic frameworks (MOFs) can be efficient precursors for synthesizing metal oxide-embedded carbon nanomaterials. Bimetallic MOF of nickel and copper was synthesized and used to prepare metal oxide of copper and nickel embedded into carbon, denoted as NiO/CuO@C. The material was characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM) image, high-resolution TEM (HR-TEM) image, and X-ray photoelectron spectroscopy (XPS). Data analysis of the material characterization confirms the synthesis of NiO/CuO@C. The electrochemical measurements of the prepared materials were investigated using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) using Nyquists plots and Bode plots. NiO/CuO@C-loaded nickel foam (NF) showed specific capacitance of 735, 536, 525, 486, 450, 400, 303, 232, and 169 F/g at scan rates of 0.5, 1, 2, 4, 10, 20, 50, 100, and 200 mV/s, respectively. The material exhibits good electrochemical performance and can be used for energy storage.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143919622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Water-Stable Homochiral 2D Zn-MOF With D-Camphorate-Derived Dicarboxylate Ligand for Enantioselective Sensing of D/L-Histidine","authors":"Kunnan Yang,&nbsp;Xuze Pan,&nbsp;Haoyu Xin,&nbsp;Xiao Zhang,&nbsp;Qingfu Zhang","doi":"10.1002/aoc.70187","DOIUrl":"https://doi.org/10.1002/aoc.70187","url":null,"abstract":"","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and Exploration of the Anti-Inflammatory and Antioxidant Potential of Silver Nanoparticle of Propolis and GC–MS Profiling","authors":"Sumaira Naz,&nbsp;Hammad Ullah,&nbsp;Muhammad Zahoor,&nbsp;Adnan Khan,&nbsp;Abdul Bari Shah,&nbsp;Riaz Ullah,&nbsp;Essam A. Ali","doi":"10.1002/aoc.70182","DOIUrl":"https://doi.org/10.1002/aoc.70182","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 &lt;p&gt;In the current study, propolis aqueous extract was utilized as biological reducing agent to fabricate its silver nanoparticles (Prop-AgNPs). First, the extract was subjected to GC–MS analysis to determine its chemical profile. After characterization, the Prop-AgNPs were evaluated for its biological potential in comparison with parental raw extract. The SEM images revealed the NPs as spherical or somewhat spherical in shape with particle size distribution ranging from 80 to 100 nm. The antioxidant potentials of the extract and fabricated nanoparticles were determined against DPPH free radical producing substantial antioxidant activities with IC&lt;sub&gt;50&lt;/sub&gt; values of 55.07 and 46.62 μg/mL correspondingly, whereas for standard ascorbic acid, its value recorded was 30.35 μg/mL. The Prop-AgNPs was then evaluated for in vivo anti-inflammatory potentials in animal model. Inflammation was induced by administering turpentine oil to lower limb of rat, and subsequently, changes in biochemical and hematological parameters were monitored. Animals were administered with doses of extract and Prop-AgNPs for 14 days, whereas biochemical parameters were monitored at day 7th and 14th of the study. Comparatively, the results were more promising on day 14th of the study. The creatinine level for the normal group were 0.55 ± 0.08 and 0.50 ± 0.04 at day 7th and 14th, whereas for negative control group, the results were 0.88 ± 0.04 (&lt;i&gt;p&lt;/i&gt; &lt; 0.001) and 0.94 ± 0.03 correspondingly; while for standard group, the recorded values were 0.57 ± 0.09 and 0.53 ± 0.07. Groups treated with 0.5 and 1 mg/kg body weight (b.w.) doses of extract has creatinine level 0.78 ± 0.23 (&lt;i&gt;p&lt;/i&gt; &lt; 0.05) and 0.69 ± 0.13 at day 7th while 0.69 ± 0.13 and 0.65 ± 1.15 at day 14th. Group treated with dose of 0.5 mg and 1 mg/kg b.w. of the synthesized nanoparticle has creatinine level 0.76 ± 0.03 and 0.63 ± 0.09 at day 7th while 0.71 ± 0.09 and 0.60 ± 0.05 at day 14th of the study. Both the extract and Prop-AgNPs normalized the level of blood urea, SGPT, bilirubin, and alkaline phosphatase compared with normal control and negative control groups among which the results of blood urea, SGPT, and alkaline phosphatase were statistically significant (&lt;i&gt;p&lt;/i&gt; &lt; 0.001). The level of hemoglobin for the normal control, negative control, and standard groups was 10.4 ± 0.13, 12.5 ± 0.68 (&lt;i&gt;p&lt;/i&gt; &lt; 0.001) and 12.4 ± 0.43 (&lt;i&gt;p&lt;/i&gt; &lt; 0.001) at day 7th, whereas at day 14th, the results were 12.1 ± 00.52, 13.8 ± 0.57 (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), and 12.6 ± 0.54 indicated more promising changes the studied parameter. The group treated with 0.5 and 1 mg/kg b.w. doses of propolis extract has hemoglobin levels 11.9 ± 0.27 (&lt;i&gt;p&lt;/i&gt; &lt; 0.001) and 11.8 ± 0.31 (&lt;i&gt;p&lt;/i&gt; &lt; 0.001) at day 7th, whereas at day 14th, the results were 12.9 ± 0.24, and 12.8 ± 0.54 while equivalent doses of nanoparticles resulted in hemoglobin level as 11.8 ± 0.38 (&lt;i&gt;p&lt;/i&gt; &lt; 0.001) and 12.7 ± 0.41","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and Characterization of Mn (II), Ni (II), and Cu (II) Complexes Derived From Sulfonamide and o-Vanillin-Based Schiff Base and Their Antimicrobial, Antioxidant, and Cytotoxic Properties","authors":"Tamanna Fariha Mitu,&nbsp;Saiful Islam,&nbsp;Shamima Akther,&nbsp;A. H. M. Shofiul Islam Molla Jamal,&nbsp;Shyama Prosad Moulick,&nbsp;Md. Najem Uddin,&nbsp;Md. Aftab Ali Shaikh,&nbsp;Pradip K. Bakshi","doi":"10.1002/aoc.70203","DOIUrl":"https://doi.org/10.1002/aoc.70203","url":null,"abstract":"<div>\u0000 \u0000 <p>A Schiff base, 4-[(2-hydroxy-3-methoxy-1-methylene)amino]benzenesulfonamide (HL), and mononuclear complexes of this with Cu (II), Ni (II), and Mn (II) have been synthesized and characterized using elemental (CHNS) and metal content analysis, molar conductivity, FT-IR, ¹H-NMR, ¹³C-NMR, UV–visible spectral studies, magnetic susceptibility measurement, LC–MS spectral analysis, thermal analysis (TGA, DTG, and DTA), and PXRD method. The proposed formulae for the complexes are [MnL₂(H₂O)₂], [NiL₂(H₂O)₂], and [CuL₂], where Schiff base acts as a bidentate <i>ON</i> chelating ligand. Octahedral geometry has been proposed for the Mn (II) and Ni (II) complexes and square planar geometry for the Cu (II) complex. The PXRD pattern reveals that Mn (II), Ni (II), and Cu (II) complexes were crystalline, with an average crystallite size ranging from 64.64 to 84.82 nm. In vitro biological activity assessments of the Schiff base and its metal complexes showed their potential bioactivity. The IC₅₀ values of the complexes indicate that Mn (II) and Cu (II) complexes have more free radical scavenging capacity compared to the parent Schiff base. Antimicrobial screening against multiple multidrug resistant Gram-positive and Gram-negative bacteria and fungi demonstrated significant antimicrobial activity for the Schiff base and its metal complexes. The LC₅₀ values from the brine shrimp lethality bioassay showed that the Schiff base along with the Mn (II) and Cu (II) complexes had a strong cytotoxicity. The Schiff base complexes exhibited a greater binding affinity for hydrogen bonds, π-sulfur, π-alkyl, and van der Waals interactions, according to the results of the molecular docking technique.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}