Harnessing the Power of Imidazolium Ionic Salts for Enhanced Suzuki–Miyaura Coupling Reactions: A Solid-State Approach

Recent advancements in modern catalysis have sparked significant interest, particularly with the integration of ionic salts. We successfully synthesized a multicationic bromide ionic salt featuring a mesitylene backbone. This study investigates a novel catalytic system comprising Pd(OAc)₂ in combination with these ionic salts in a molar ratio of 2:20, for solid-state Suzuki–Miyaura coupling reactions. The catalytic system underwent comprehensive characterization utilizing various analytical techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS). This methodology proves to be an efficient and operationally convenient approach for synthesizing a diverse array of biaryls under mild conditions, achieving excellent yields and turnover numbers (TONs) ranging from 462.35 to 547.05, with turnover frequencies (TOFs) between 21.01 and 51.79 min⁻¹. Notably, the catalytic system exhibited at least five times recyclability, maintaining good catalytic efficiency.