APL Materials最新文献_第5页

Material discovery and modeling acceleration via machine learning 通过机器学习加速材料发现和建模

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-09-04 DOI: 10.1063/5.0230677

Carmine Zuccarini, Karthikeyan Ramachandran, Doni Daniel Jayaseelan

引用次数: 0

Nanozyme microspheres with structural color-coding labels for synergistic therapy of psoriasis 用于银屑病协同治疗的带结构色标的纳米酶微球

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-09-03 DOI: 10.1063/5.0229803

Nengjie Yang, Yuting Huang, Chen Dong, Chi Sun, Peipei Xi, Yuexiao Dai, Rui Zhao, Yunan Wang, Yujuan Zhu, Zhifeng Gu

{"title":"Nanozyme microspheres with structural color-coding labels for synergistic therapy of psoriasis","authors":"Nengjie Yang, Yuting Huang, Chen Dong, Chi Sun, Peipei Xi, Yuexiao Dai, Rui Zhao, Yunan Wang, Yujuan Zhu, Zhifeng Gu","doi":"10.1063/5.0229803","DOIUrl":"https://doi.org/10.1063/5.0229803","url":null,"abstract":"Psoriasis is an immune system-mediated skin disease identified by the appearance of erythematous as a central symptom. As a recurrent and chronic inflammatory disease, psoriasis is influenced by both genetic and environmental factors and is known to be with no effective cure. Considering a multifaceted etiology of psoriasis, synergistic therapy exhibits great benefits over monotherapy, which becomes common for the treatment of various diseases. Herein, we present the nanozyme microspheres with structural color-coding labels for synergistic therapy of psoriasis. In particular, microsphere hydrogel is fabricated by the edible hydroxypropyl cellulose (HPC), which can generate a photonic liquid crystalline mesophase under lyotropic conditions in solution. Through adjustment of hydrogel components, microspheres endow with different functions, including moisturizing (paraffin), cfDNA scavenging (chitosan), and anti-inflammation (cerium oxide nanozyme). To improve patient convenience, hydrogel drops with different properties are tailored with different vivid structural colors by exploiting the lyotropic behavior of HPC. Of particular note, both in vitro and in vivo experiments have demonstrated the significant therapeutic effects of the encoded structural color microspheres. Green moisturizing microspheres facilitate to relieve dry, flaky skin patches; blue cfDNA scavenging and red anti-inflammatory microspheres significantly reduce skin inflammation. More importantly, combination therapy with encoded microspheres exerted the synergistic effects, including the increased body weight, thicker epidermal layer, and reduced immune activation. Overall, this synergistic treatment offers a promising platform for personalized management of psoriasis and various inflammatory skin diseases.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"79 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visible/near-infrared luminescence and concentration effects of Pr3+-doped Sr2Al2GeO7 downconversion phosphors 掺杂 Pr3+ 的 Sr2Al2GeO7 下转换荧光粉的可见光/近红外发光和浓度效应

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-09-03 DOI: 10.1063/5.0226329

Tiantian Shen, Shanshan Zhao, An Su, Haisheng Liu, Fayi Chen, Benchun Li, Xinxin Han, Dechao Yu, Dawei Zhang

{"title":"Visible/near-infrared luminescence and concentration effects of Pr3+-doped Sr2Al2GeO7 downconversion phosphors","authors":"Tiantian Shen, Shanshan Zhao, An Su, Haisheng Liu, Fayi Chen, Benchun Li, Xinxin Han, Dechao Yu, Dawei Zhang","doi":"10.1063/5.0226329","DOIUrl":"https://doi.org/10.1063/5.0226329","url":null,"abstract":"The Pr3+ ion has been widely doped into various materials as a red and near-infrared (NIR) emitting center for applications in lighting and solar spectrum downconversion. Herein, the preparation of a new library of Pr3+-doped Sr2Al2GeO7 phosphors was proved by powder x-ray diffraction patterns and Rietveld refinements and characterized by a scanning electron microscope with energy-dispersive x-ray spectrometry. The Sr2Al2GeO7:Pr3+ sample strongly absorbs blue photons over 420–500 nm and yields intense visible emissions with dominant peaks around 490 nm from the Pr3+ 3P0 → 3H4 transition, as well as robust NIR emission bands over 800–1200 nm. In addition to the typical transitions of 1D2 → 3F2 at 880 nm, 1G4 → 3H4 at 1000 nm, and 1D2 → 3F3,4 at 1070 nm, the distinguishable NIR emission at 929 nm was demonstrated from the 3P0 → 1G4 transition via static and dynamic spectroscopic analysis. Most interestingly, for the 3P0 blue-excited state, a considerably elevated concentration of about 10%Pr3+ was optimal for the visible/NIR emissions, in stark contrast to the diluted optimal 1%Pr3+ for the 1D2 state. The relevant cross-relaxation from the 3P0 and 1D2 states between Pr3+ was comprehensively treated by theoretical speculations and experimental results. Such concentrated Pr3+ blue activators would significantly facilitate the blue-to-NIR downconversion through a desired two-step sequential transition from the 3P0 initial state to the 1G4 intermediate level for quantum efficiency exceeding unity. The current results would consolidate the basis of concentrated Pr3+ donors to promote the novel Pr3+/Yb3+ codoping downconversion for greatly increasing Si solar cell efficiency.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"17 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnetic casein/CaCO3/Fe3O4 microspheres stimulate osteogenic differentiation 磁性酪蛋白/CaCO3/Fe3O4 微球刺激成骨分化

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-09-03 DOI: 10.1063/5.0229172

Mingjie Zhang, Xiaolei Li, Han Lin

{"title":"Magnetic casein/CaCO3/Fe3O4 microspheres stimulate osteogenic differentiation","authors":"Mingjie Zhang, Xiaolei Li, Han Lin","doi":"10.1063/5.0229172","DOIUrl":"https://doi.org/10.1063/5.0229172","url":null,"abstract":"The quality of life is significantly impacted by bone defects, which calls for the creation of optimum restorative materials with particular qualities. Current repair materials, such as metal alloys, polymer scaffolds, and bone cement, have a number of drawbacks, such as poor fracture toughness, non-degradability, and insufficient osteogenic ability. To address these challenges, we designed a novel magnetic casein/CaCO3/Fe3O4 microspheres (CCFM), combining biodegradability, osteoinductivity, osteoconductivity, and osteogenesis properties together. In vitro studies confirmed the outstanding biocompatibility and osteogenic differentiation effects on MC3T3-E1 cells of CCFM, highlighting their potential as a promising bone regeneration platform for clinical applications. As a novel bone repair material with superparamagnetic properties, CCFM not only possess good osteoinductivity, osteoconductivity, and osteogenesis properties but also can remain in the lesion location for a long time under an external magnetic field, representing a significant advancement in the field of bone tissue engineering and offering new possibilities for effective bone defect remediation and patient care.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"45 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilizing (Al, Ga)2O3/Ga2O3 superlattices to measure cation vacancy diffusion and vacancy-concentration-dependent diffusion of Al, Sn, and Fe in β-Ga2O3 利用（Al, Ga）2O3/Ga2O3 超晶格测量阳离子空位扩散以及β-Ga2O3 中铝、锡和铁随空位浓度变化的扩散情况

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-08-30 DOI: 10.1063/5.0206398

Nathan D. Rock, Haobo Yang, Brian Eisner, Aviva Levin, Arkka Bhattacharyya, Sriram Krishnamoorthy, Praneeth Ranga, Michael A. Walker, Larry Wang, Ming Kit Cheng, Wei Zhao, Michael A. Scarpulla

{"title":"Utilizing (Al, Ga)2O3/Ga2O3 superlattices to measure cation vacancy diffusion and vacancy-concentration-dependent diffusion of Al, Sn, and Fe in β-Ga2O3","authors":"Nathan D. Rock, Haobo Yang, Brian Eisner, Aviva Levin, Arkka Bhattacharyya, Sriram Krishnamoorthy, Praneeth Ranga, Michael A. Walker, Larry Wang, Ming Kit Cheng, Wei Zhao, Michael A. Scarpulla","doi":"10.1063/5.0206398","DOIUrl":"https://doi.org/10.1063/5.0206398","url":null,"abstract":"Diffusion of native defects such as vacancies and their interactions with impurities are fundamental to semiconductor crystal growth, device processing, and design. However, the transient equilibration of native defects is difficult to directly measure. We used (AlxGa1−x)2O3/Ga2O3 superlattices (SLs) to detect and analyze transient diffusion of cation vacancies during annealing in O2 at 1000–1100 °C. Using a novel finite difference scheme for diffusion with time- and space-varying diffusion constants, we determined diffusion constants for Al, Fe, and cation vacancies, including the vacancy concentration dependence for Al. In the case of SLs grown on Sn-doped β-Ga2O3 (010) substrates, gradients observed in the extent of Al diffusion indicate a supersaturation of vacancies in the substrates that transiently diffuse through the SLs coupled strongly to Sn and thus slowed compared to undoped cases. In the case of SLs grown on (010) Fe-doped substrates, the Al diffusion is uniform through the SLs, indicating a depth-uniform concentration of vacancies. We find no evidence for the introduction of VGa from the free surface at rates sufficient to affect Al diffusion at at. % concentrations, establishing an upper bound on surface injection. In addition, we show that unintentional impurities in Sn-doped Ga2O3 such as Fe, Ni, Mn, Cu, and Li also diffuse toward the surface and accumulate. Many of these likely have fast interstitial diffusion modes capable of destabilizing devices, thus suggesting that impurities may require further reduction. This work provides a method to measure transients in diffusion-mediating native defects otherwise hidden in common processes such as ion implantation, etching, and film growth.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"171 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrical conductivity anisotropy of InGaZn3O6 single crystals by pressurized optical floating zone growth and its oxygen annealing effect 加压光学浮区生长 InGaZn3O6 单晶的电导率各向异性及其氧退火效应

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-08-30 DOI: 10.1063/5.0218948

N. Kase, Y. Kawamura, Y. Kobayashi, T. Inoue, K. Tanaka, N. Miyakawa

引用次数: 0

Synergizing intrinsic symmetry breaking with spin–orbit torques for field-free perpendicular magnetic tunnel junction 无磁场垂直磁隧道结的本征对称性破缺与自旋轨道力矩协同作用

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-08-30 DOI: 10.1063/5.0221776

Jing Zhou, Lisen Huang, Sherry Lee Koon Yap, Dennis Jing Xiong Lin, Bingjin Chen, Shaohai Chen, Seng Kai Wong, Jinjun Qiu, James Lourembam, Anjan Soumyanarayanan, Sze Ter Lim

{"title":"Synergizing intrinsic symmetry breaking with spin–orbit torques for field-free perpendicular magnetic tunnel junction","authors":"Jing Zhou, Lisen Huang, Sherry Lee Koon Yap, Dennis Jing Xiong Lin, Bingjin Chen, Shaohai Chen, Seng Kai Wong, Jinjun Qiu, James Lourembam, Anjan Soumyanarayanan, Sze Ter Lim","doi":"10.1063/5.0221776","DOIUrl":"https://doi.org/10.1063/5.0221776","url":null,"abstract":"Current-induced spin–orbit torque (SOT) facilitates the ultrafast electrical manipulation of magnetic tunnel junction (MTJ), which is a leading non-volatile technology for the microelectronic industry. The key bottleneck to the commercial application of SOT-MTJ is the absence of a practicable symmetry-breaking scheme to switch perpendicular magnetization without an external magnetic field. Here, we demonstrate the wafer-scale realization of internalized field-free switching in perpendicular SOT-MTJ using conventional materials and device structure. We utilize a dual-function tungsten (W) spacer, which generates sizable SOT while concomitantly breaking symmetry via interlayer exchange coupling (IEC). Tuning the W thickness enables field-free switching with two types of IEC. An optimized combination of SOT and IEC ensures competitive switching performance, with our device exhibiting excellent thermal stability, low switching current density, and fast operating speed. This work builds the long-sought bridge between SOT manipulation of magnetization and wafer-scale field-free perpendicular MTJ. It underscores the urgent need to incorporate perpendicular SOT-MTJ in integrated circuits for applications in logic, memory, and unconventional computing.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"27 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling charge transport in monolayer and few-layer CoPS3/metal contact: Insight from C-AFM 揭示单层和少层 CoPS3/金属接触中的电荷传输：C-AFM 的洞察力

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-08-28 DOI: 10.1063/5.0222472

Mouhui Yan, Haotian Wang, Wenqi Wei, Tianxiang Zhu, Guanghui Cao, Jianxin Zhong, Wei Ren

引用次数: 0

Immunomodulatory hydrogels for tissue repair and regeneration 用于组织修复和再生的免疫调节水凝胶

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-08-23 DOI: 10.1063/5.0228692

Xiangjun Liu, Yue Hu, Yikun Ju, Pu Yang, Naisi Shen, Anqi Yang, Rui Wu, Bairong Fang, Liangle Liu

{"title":"Immunomodulatory hydrogels for tissue repair and regeneration","authors":"Xiangjun Liu, Yue Hu, Yikun Ju, Pu Yang, Naisi Shen, Anqi Yang, Rui Wu, Bairong Fang, Liangle Liu","doi":"10.1063/5.0228692","DOIUrl":"https://doi.org/10.1063/5.0228692","url":null,"abstract":"Tissue repair and regeneration have long been a focus of research, with growing evidence highlighting the role played by immunomodulation. The repair of tissue cells can be significantly promoted through the localized immunomodulation of tissues. Hydrogels are increasingly used in this field due to their biocompatibility, versatility, and relative ease of fabrication. This Review highlights the critical role of inflammation and immune development in the complex process of tissue repair after injury, highlighting the dynamic interactions between immune cells that ultimately influence the outcome of tissue healing. We also summarize the precise functions of immune cells and their responses in various tissue injury scenarios, which are critical for harnessing the full potential of immunomodulatory strategies to promote tissue repair. We discuss recent advances in drug-carrying hydrogels, which offer promising avenues for tissue regeneration with precise control of the immune environment for constructive tissue repair. Further advances in our understanding of the mechanisms driving inflammation and immune cell behavior during tissue injury are expected to foster the development of increasingly effective hydrogel-based immunomodulatory strategies to promote tissue repair and regeneration.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"3 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing terahertz magneto-optical effects in wafer-scale RIG single crystal thick films with anti-reflective coatings for improved transmittance 利用抗反射涂层增强晶圆级 RIG 单晶厚膜的太赫兹磁光效应，从而提高透射率

IF 6.1 2区材料科学

APL Materials Pub Date : 2024-08-19 DOI: 10.1063/5.0219811

Qiang Xue, Yuan-Jing Zhang, Qing-Hui Yang, Huai-Wu Zhang, Qi-Ye Wen

{"title":"Enhancing terahertz magneto-optical effects in wafer-scale RIG single crystal thick films with anti-reflective coatings for improved transmittance","authors":"Qiang Xue, Yuan-Jing Zhang, Qing-Hui Yang, Huai-Wu Zhang, Qi-Ye Wen","doi":"10.1063/5.0219811","DOIUrl":"https://doi.org/10.1063/5.0219811","url":null,"abstract":"Wafer-scale rare-earth iron garnet (RIG) single crystal thick films were fabricated on 3-in. gadolinium gallium garnet (GGG) substrates using liquid phase epitaxy. The terahertz transmittance of the RIG crystals improved after removing the GGG substrate by polishing. The time-domain spectra at Terahertz (THz) frequencies indicate the existence of a magneto-optical effect in RIG samples. The results indicate that the RIG samples exhibit a high refractive index of ∼4.50 within the 0.1–1.0 THz frequency range, a transmittance of around 40%, and an absorption rate of only 10–50 cm−1. The Faraday rotation angles of the thick single-crystal films of the RIG samples were measured using a THz-TDS system. The RIG has a thickness of ∼330 μm. The Faraday rotation angles of RIG crystals at THz frequencies can reach up to 16° when an external magnetic field of 0.18 T is applied. The Verdet constants of the RIG sample were calculated to be ∼120°/mm/T. To improve the transmittance of the RIG sample, epoxy resin and polymethylpentene (TPX) were used as anti-reflective films. The transmittance of the RIG sample increased by ∼5% for the 80 μm thick epoxy and about 10% for the 320 μm thick TPX. Therefore, this RIG single crystal thick film can achieve a low loss, a high transmittance, and a strong magneto-optical effect in the terahertz region with the cooperation of a reflection-reducing film. It is expected to have wide applications in terahertz magnetic polarization conversion, non-reciprocal phase shifters, and isolators.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"71 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0