Reports (MDPI)最新文献_第5页

Pneumomediastinum, Pneumothorax and Subcutaneous Emphysema - A Rare Form of Presentation for Severe COVID-19 Pneumonia 纵隔肺炎、胸腔肺炎和皮下气肿——严重新冠肺炎肺炎的罕见表现形式

Reports (MDPI) Pub Date : 2023-03-16 DOI: 10.11648/j.reports.20230302.11

S. Hasanzadeh, Ali Mehri, K. Ghazvini, Z. Ataee

引用次数: 0

Paroxysmal Atrial Fibrillation with Rapid Ventricular Response Following COVID-19 Nasopharyngeal Swab: A Case Report COVID-19鼻咽拭子术后阵发性心房颤动伴快速心室反应1例报告

Reports (MDPI) Pub Date : 2023-03-15 DOI: 10.3390/reports6010015

M. Viscusi, L. Ambrosio, D. Ricciardi, F. Mangiacapra, A. Nusca, Luca Paolucci, G. Ussia, F. Grigioni

引用次数: 0

On the Historical Data Collection and Study of the Culture of Mountain Tai Heaver 论泰山鹤文化的史料收集与研究

Reports (MDPI) Pub Date : 2023-03-15 DOI: 10.11648/j.reports.20230301.11

Mingjie Sun

引用次数: 0

A Rare Case of Malignant Ovarian Germ Cell Tumor: Dysgerminoma and Seminoma in the Same Patient 卵巢恶性生殖细胞瘤1例:异常生殖细胞瘤与精原细胞瘤合并

Reports (MDPI) Pub Date : 2023-03-03 DOI: 10.3390/reports6010014

M. Mitranovici, D. Chiorean, S. Turdean, Maria-Cezara Muresan, C. Buicu, R. Moraru, L. Moraru, T. Cotoi, Havva Serap Toru, A. Apostol, C. Mǎrginean, Ion Petre, Ioan Emilian Oală, Viviana Ivan, O. Cotoi

{"title":"A Rare Case of Malignant Ovarian Germ Cell Tumor: Dysgerminoma and Seminoma in the Same Patient","authors":"M. Mitranovici, D. Chiorean, S. Turdean, Maria-Cezara Muresan, C. Buicu, R. Moraru, L. Moraru, T. Cotoi, Havva Serap Toru, A. Apostol, C. Mǎrginean, Ion Petre, Ioan Emilian Oală, Viviana Ivan, O. Cotoi","doi":"10.3390/reports6010014","DOIUrl":"https://doi.org/10.3390/reports6010014","url":null,"abstract":"Ovarian malignant germ cell tumors (OMGCTs) represent a rare type of malignant tumors composed of primitive germ cells that often originate from dysgenetic gonads and are frequently associated with hermaphroditism. Such tumors occur more frequently in adolescents or young adults, and their etiopathogenic mechanism is not well established. We report the case of a 20-year-old female with ovarian dysgenesis and female phenotype. A laparoscopic surgery was performed, and ovotestis was discovered. To achieve a histopathological examination, right oophorectomy was performed, which confirmed the diagnosis of dysgerminoma. In the case of hermaphroditism, mixed germ cell tumors can develop, leading to a more aggressive evolution with bilateral malignancy of the gonads, which requires the removal of both ovotestis. The patient was recalled. A histopathological examination revealed a seminoma, so laparoscopic left oophorectomy was performed. The management of this type of diagnosis primarily involves surgery, minimally invasive interventions being preferred. Not all pathologic conditions are readily identifiable by means of exploratory laparoscopy, as in our patient’s case. We consider that the optimal solution for these patients would be the preservation of fertility via egg donation and embryo transfer; the survival rate of such patients being 97–100%, if the tumor is diagnosed at an early age.","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42289643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Favorable Outcome and Safety of Neoadjuvant Trastuzumab Emtansine (T-DM1) in a HER2-Positive Early Breast Cancer Patient with Severe Renal Disease on Hemodialysis Ineligible for Conventional Chemotherapy: A Case Report 新辅助曲妥珠单抗Emtansine (T-DM1)治疗her2阳性早期乳腺癌伴严重肾脏疾病的血液透析不适合常规化疗患者的良好结局和安全性:1例报告

Reports (MDPI) Pub Date : 2023-03-02 DOI: 10.3390/reports6010013

Suman Kalyan Natarajan, Joice Crystal Danansezhian, Vipul R. Thummar, P. Mehta

{"title":"Favorable Outcome and Safety of Neoadjuvant Trastuzumab Emtansine (T-DM1) in a HER2-Positive Early Breast Cancer Patient with Severe Renal Disease on Hemodialysis Ineligible for Conventional Chemotherapy: A Case Report","authors":"Suman Kalyan Natarajan, Joice Crystal Danansezhian, Vipul R. Thummar, P. Mehta","doi":"10.3390/reports6010013","DOIUrl":"https://doi.org/10.3390/reports6010013","url":null,"abstract":"Breast cancer is the leading cause of cancer-related death among women worldwide. It is the most common malignancy in middle-age and elderly women already suffering from other comorbidities, such as chronic kidney disease (CKD). Being a heterogeneous disease, it has variable subtype-specific outcomes and responses towards treatment. Patients with human epidermal growth factor receptor 2 (HER2) overexpression are treated with anti-HER2-targeted drugs. With the advent of newer drugs, the usage of HER2 blockade and chemotherapy in the neoadjuvant treatment of HER2-positive early breast cancer management helps to increase the probability of achieving pathological complete response. We herein present a case of a patient with breast cancer with long-standing CKD and on maintenance hemodialysis where treatment with conventional chemotherapy regimens was a concern and managed with an antibody–drug conjugate (ADC), namely T-DM1, in a neoadjuvant setting. The patient showed a favorable outcome, and the tolerance of T-DM1 in this patient was predictable. This is a first-of-its-kind case report, where T-DM1 was used in a neoadjuvant setting for a patient on simultaneous hemodialysis.","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42516498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Durability and Efficacy of Cryopreserved Human Umbilical Cord Tissue Allograft for the Supplementation of Cartilage Defects Associated with the Sacroiliac Joint: A Case Series 低温保存的人脐带同种异体组织移植治疗骶髂关节软骨缺损的耐久性和有效性:一个病例系列

Reports (MDPI) Pub Date : 2023-03-02 DOI: 10.3390/reports6010012

A. Lai, Jon Shou, Steve A. Traina, Tyler C. Barrett

引用次数: 0

A Possible New Diagnostic Method for Early Diagnosis of Cryptococcus Infection in Lymphoma Patient Co-Infected with SARS-CoV-2 SARS-CoV-2合并淋巴瘤患者隐球菌感染早期诊断的可能新方法

Reports (MDPI) Pub Date : 2023-03-01 DOI: 10.3390/reports6010011

M. Colosimo, S. Nisticò, F. Quintieri, A. De Luca, P. Minchella, L. Gallelli

引用次数: 0

Scanning Electron Microscopy of Conjunctival Scraping: Our Experience in the Diagnosis of Infectious Keratitis with Negative Culture Tests 结膜刮削扫描电镜:培养阴性诊断感染性角膜炎的经验

Reports (MDPI) Pub Date : 2023-02-27 DOI: 10.3390/reports6010010

M. Troisi, Salvatore Del Prete, Salvatore Troisi, Daniela Marasco, C. Costagliola

{"title":"Scanning Electron Microscopy of Conjunctival Scraping: Our Experience in the Diagnosis of Infectious Keratitis with Negative Culture Tests","authors":"M. Troisi, Salvatore Del Prete, Salvatore Troisi, Daniela Marasco, C. Costagliola","doi":"10.3390/reports6010010","DOIUrl":"https://doi.org/10.3390/reports6010010","url":null,"abstract":"65 consecutive patients with presumed microbial keratitis and negative culture tests for bacteria and fungi obtained by corneal curettage were evaluated. All patients had undergone local broad spectrum antibiotic therapy for at least 5 days with no clinical improvement. After 48–72 h of wash-out they underwent scraping of the superior tarsal conjunctiva for cytological examination of cellular morphology in Scanning Electron Microscopy (SEM). The presence of pathogenic microorganisms was detected with this method in 62 of these patients, towards which specific therapy was carried out. Clinical improvement and eradication of microorganisms previously detected by SEM examination were observed in all positive patients over a time between 10 and 49 days. In three patients, no microorganisms were detected, but the presence of inflammatory cells (eosinophils and mast cells) or dry eye findings. This method could be useful to detect the presence of non-isolated microorganisms at common culture tests. The resolution of the infectious keratitis and the eradication of the pathogens at the subsequent cytological examination of cellular morphology in Scanning Electron Microscopy support the validity of the proposed method.","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45484231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Risk of the Development of Secondary Post-Traumatic Stress Disorder among Pediatric Health Care Providers: A Systematic Review 继发性创伤后应激障碍在儿科卫生保健提供者中的发展风险:一项系统综述

Reports (MDPI) Pub Date : 2023-02-23 DOI: 10.3390/reports6010009

N. Rigas, A. Soldatou, M. Dagla, C. Nanou, E. Antoniou

{"title":"The Risk of the Development of Secondary Post-Traumatic Stress Disorder among Pediatric Health Care Providers: A Systematic Review","authors":"N. Rigas, A. Soldatou, M. Dagla, C. Nanou, E. Antoniou","doi":"10.3390/reports6010009","DOIUrl":"https://doi.org/10.3390/reports6010009","url":null,"abstract":"Background: Secondary PTSD is defined as the natural, consequential behaviors and emotions that result from knowledge about a traumatic event experienced by a significant other deriving from working with suffering individuals. Pediatric health providers with symptoms of PTSD report problems with relationships and general life dissatisfaction as well as and anxiety, depression and burnout syndrome. Aim: The aim of this systematic review was to estimate the risk of developing secondary PTSD among pediatric health care providers as well as all additional contributing factors. In more detail, we investigated the PTSD symptomatology between pediatric health care providers and the extent to which parameters such as the job, gender, department and other factors had an impact on the mental health status of pediatric health care providers. Methodology: We searched all published English papers in PubMed, Google Scholar and the Cochrane Library from September to November 2022. We excluded reviews, systematic reviews and meta-analyses as well as letters to editors. From a total of 748 papers, we included only 12 research articles that met the admission criteria. Results: According to our results, the prevalence of secondary PTSD ranges from 13% to 94%. Burnout, nurses, the female gender, intensive care units, past traumatic life events and a psychiatric history identified as factors contributing to the development of secondary PTSD. Conclusions: Health policy-makers should take the specificity in the working environment of the pediatric sector seriously into consideration, especially emergency departments.","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45426628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Mandibular Condyle Xanthoma: Case Report and Literature Review 原发性下颌髁黄色瘤1例报告及文献复习

Reports (MDPI) Pub Date : 2023-02-15 DOI: 10.3390/reports6010006

Sara Negrello, Arrigo Pellacani, M. Di Bartolomeo, G. Pollastri, A. Anesi

引用次数: 0