Reports (MDPI)最新文献_第10页

Possibility to Open Up New Areas by COVID-19 Infection COVID-19感染开辟新领域的可能性

Reports (MDPI) Pub Date : 2022-05-22 DOI: 10.3390/reports5020016

Toshio Hattori, Y. Ashino

引用次数: 0

A Novel Case of Recurrent Mucinous Borderline Ovarian Tumor: Early Relapse and Fatal Outcome 一例复发性黏液性交界性卵巢肿瘤的早期复发和死亡结局

Reports (MDPI) Pub Date : 2022-05-12 DOI: 10.3390/reports5020015

K. Nakagawa, K. Nakayama, Akiho Nakamura, Nagisa Hadano, Sonomi Kurose, S. Razia, S. Aoki, S. Kyo

{"title":"A Novel Case of Recurrent Mucinous Borderline Ovarian Tumor: Early Relapse and Fatal Outcome","authors":"K. Nakagawa, K. Nakayama, Akiho Nakamura, Nagisa Hadano, Sonomi Kurose, S. Razia, S. Aoki, S. Kyo","doi":"10.3390/reports5020015","DOIUrl":"https://doi.org/10.3390/reports5020015","url":null,"abstract":"Unlike ovarian carcinomas, borderline ovarian tumors (BOTs) are associated with a favorable prognosis: their recurrence rate is around 5–7%, and the survival rate is more than 97% when diagnosed early. There are only a few reports of recurrence and fatal outcomes. Herein, we report a novel case of recurrent mucinous BOT, with a literature review. A 63-year-old woman presented to a local doctor with abdominal fullness. She was diagnosed as having a polycystic tumor. The lesion was suspected to be a mucinous BOT (M-BOT) on magnetic resonance imaging. Upper and lower gastrointestinal endoscopy revealed no digestive cancerous lesions, and surgery was performed. Intra-operative diagnosis confirmed the diagnosis, and total abdominal hysterectomy, bilateral salpingo-oophorectomy, and omentectomy were performed. The final pathological diagnosis was non-invasive M-BOT (stage I c1 (T1c1N0M0)). The result of immunohistochemical staining supported the diagnosis of primary ovarian mucinous tumor.Four months after surgery, relapse occurred. Blood tests revealed an elevated carbohydrate antigen 19-9 level, and computed tomography revealed multiple liver metastases, peritoneal dissemination, left ureter infiltration, and carcinomatous peritonitis. Although the patient underwent chemotherapy, she died. This case of a very short progression-free and overall survival in stage I M-BOT indicates that some M-BOTs could result in fatal clinical outcomes despite diagnosis at an early stage. Frequent follow-up appointments after surgery could help detect relapse and increase survival in such cases.","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42781131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Allplex™ 2019-nCoV and TaqPath™ COVID-19 Assays Allplex™2019-nCoV和TaqPath™COVID-19检测方法的比较

Reports (MDPI) Pub Date : 2022-04-26 DOI: 10.3390/reports5020014

M. Colosimo, P. Minchella, Rossana Tallerico, Ilenia Talotta, C. Peronace, L. Gallelli, G. Di Mizio, E. Cione

{"title":"Comparison of Allplex™ 2019-nCoV and TaqPath™ COVID-19 Assays","authors":"M. Colosimo, P. Minchella, Rossana Tallerico, Ilenia Talotta, C. Peronace, L. Gallelli, G. Di Mizio, E. Cione","doi":"10.3390/reports5020014","DOIUrl":"https://doi.org/10.3390/reports5020014","url":null,"abstract":"The clinical presentation of COVID-19 is non-specific, and to improve and limit the spread of the SARS-CoV-2 virus, an accurate diagnosis with a robust method is needed. A total of 500 nasopharyngeal swab specimens were tested for SARS-CoV-2. Of these, 184 samples were found to be positive with Allplex™ 2019-nCoV Assay, which is fully automated. All the positive samples were retested with TaqPath™ COVID-19 CE-IVD RT-PCR Kit (after this, referred to as TaqPath™ COVID-19), semi-automated. The comparison of RT-qPCR for SARS-CoV-2 genes target points shows only one target point in common, the N gene. Therefore, the N gene was used to compare both assays. We noticed different Ct values between the tests. Therefore, samples were divided into four groups depending to the Ct value results: (1) Ct < 25, (2) Ct 25–30, (3) Ct 30–35, (4) Ct > 35. TaqPath™ COVID-19 Kit reconfirmed the results obtained from Allplex™ 2019-nCoV Assay. In conclusion, both the Allplex™ 2019-nCoV assay and TaqPath™ COVID-19 tests accurately confirm the diagnosis of SARS-CoV-2 infection. Even if TaqPath™ COVID-19 has a semi-automated workflow, it does not introduce bias in the diagnostic screening of SARS-CoV-2, and it supports the indirect identification of variants of concern to undergo sequencing.","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41334609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Ketogenic Diet and Physical Exercise on Managing Tarlov Cysts: A Case Report 生酮饮食和体育锻炼治疗Tarlov囊肿一例报告

Reports (MDPI) Pub Date : 2022-03-29 DOI: 10.3390/reports5020012

Roberto Cannataro, C. Di Lorenzo, Mario Iazzolino, M. Caroleo, L. Gallelli, G. De Sarro, E. Cione

引用次数: 0

Spontaneous Post-COVID-19 Pneumothorax in a Patient with No Prior Respiratory Tract Pathology: A Case Report 无呼吸道病理的covid -19后自发性气胸1例

Reports (MDPI) Pub Date : 2022-03-21 DOI: 10.3390/reports5010011

V. Grigorov, M. Grigorov, E. Grigorov, H. Nocheva

引用次数: 1

Ameloblastoma in a Three-Year-Old Child with Hurler Syndrome (Mucopolysaccharidosis Type I) Hurler综合征（I型粘多糖病）三岁儿童成釉细胞瘤

Reports (MDPI) Pub Date : 2022-03-15 DOI: 10.3390/reports5010010

M. Di Bartolomeo, Arrigo Pellacani, Sara Negrello, Martina Buchignani, R. Nocini, Gianluca Di Massa, Greta Gianotti, G. Pollastri, G. Colletti, L. Chiarini, A. Anesi

{"title":"Ameloblastoma in a Three-Year-Old Child with Hurler Syndrome (Mucopolysaccharidosis Type I)","authors":"M. Di Bartolomeo, Arrigo Pellacani, Sara Negrello, Martina Buchignani, R. Nocini, Gianluca Di Massa, Greta Gianotti, G. Pollastri, G. Colletti, L. Chiarini, A. Anesi","doi":"10.3390/reports5010010","DOIUrl":"https://doi.org/10.3390/reports5010010","url":null,"abstract":"Mucopolysaccharidoses (MPS) are a family of genetic diseases associated with a deficiency of alpha-L iduronidase, which causes a lack of catabolism of glycosaminoglycans (GAGs). Therefore, the accumulation of GAGs determines a wide spectrum of symptoms, typically found in a few syndromes like Hurler syndrome (HS). Among other specific manifestations, craniofacial abnormalities are crucial for the characterization of this syndrome. Ameloblastoma is a rare, benign, slow-growing, odontogenic tumor usually located in the mandible. Clear risk factors for the development of ameloblastoma remain unknown, but black patients have a fivefold increased risk. Clinically, it is characterized by a painless, variable-sized jaw swelling. Although classified as a benign tumor, ameloblastoma often has a severe clinical outcome. The most common type of ameloblastoma is the solid/multicystic/conventional one. A computed tomography scan (CT) with and without contrast is the gold standard for evaluating this kind of neoplasia. Conservative or radical surgery is the mainstay of treatment. In this case report, we described an unusual clinical assessment of conventional ameloblastoma interesting the posterior left mandible of a 35-month-old child affected by HS. This case represented a suggestive challenge both from a diagnostic and a therapeutic point of view. The patient was disease-free at 2 years’ follow-up.","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43976536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Intradural Lumbar Disc Herniation: Updated Report of a Case with Literature Review 硬膜内腰椎间盘突出:1例最新报告并文献回顾

Reports (MDPI) Pub Date : 2022-03-11 DOI: 10.3390/reports5010009

Hoang-Long Nguyen, Manh-Hung Do, Hoang-Long Vo, Bao-Tien L. Nguyen

引用次数: 0

A Case of Recent Liver Injury Induced by Benzbromarone 苯溴马隆致近期肝损伤1例

Reports (MDPI) Pub Date : 2022-03-08 DOI: 10.3390/reports5010008

Tomotaka Ishii, Keijiro Hoshino, Masayuki Honda, Yoichiro Yamana, Reina Sasaki-Tanaka, M. Kumagawa, Shini Kanezawa, Taku Mizutani, Naoki Matsumoto, R. Masuzaki, K. Nirei, Hiroaki Yamagami, M. Moriyama, T. Kanda

引用次数: 0

Seminar Lessons: Infectious Diseases Associated with and Causing Disaster 研讨会课程：与灾害相关的传染病

Reports (MDPI) Pub Date : 2022-02-28 DOI: 10.3390/reports5010007

Toshio Hattori, Haorile Chagan-Yasutan, Shinsuke Koga, Yasutake Yanagihara, Issei Tanaka

{"title":"Seminar Lessons: Infectious Diseases Associated with and Causing Disaster","authors":"Toshio Hattori, Haorile Chagan-Yasutan, Shinsuke Koga, Yasutake Yanagihara, Issei Tanaka","doi":"10.3390/reports5010007","DOIUrl":"https://doi.org/10.3390/reports5010007","url":null,"abstract":"Disasters such as the magnitude-9 Great East Japan Earthquake occur periodically. We considered this experience while developing measures against a predicted earthquake in the Nankai Trough. This report includes a summary of 10 disastrous infectious diseases for which a countermeasures seminar was held. Thirty-five speakers from twenty-one organizations performed the lectures. Besides infectious diseases, conference topics also included disaster prevention and mitigation methods. In addition, the development of point-of-care tests, biomarkers for diagnosis, and severity assessments for infectious diseases were introduced, along with epidemics of infectious diseases affected by climate. Of the 28 pathogens that became a hot topic, 17 are viruses, and 14 out of these 17 (82%) are RNA viruses. Of the 10 seminars, the last 2 targeted only COVID-19. It was emphasized that COVID-19 is not just a disaster-related infection but a disaster itself. The first seminar on COVID-19 provided immunological and epidemiological knowledge and commentary on clinical practices. During the second COVID-19 seminar, vaccine development, virological characteristics, treatment of respiratory failure, biomarkers, and human genetic susceptibility for infectious diseases were discussed. Conducting continuous seminars is important for general infectious controls.","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41814422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Reminder of an Important Clinical Lesson: Hypoxaemia in a Pleural Effusion 提醒一个重要的临床教训:胸腔积液中的低氧血症

Reports (MDPI) Pub Date : 2022-02-17 DOI: 10.3390/reports5010006

A. Aujayeb

引用次数: 0