GMS ophthalmology cases最新文献_第2页

Radius-Maumenee syndrome (idiopathic dilated episcleral vessels). Radius-Maumenee综合征（特发性外膜血管扩张）。

GMS ophthalmology cases Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3205/oc000247

Carolina Tagliari Estacia, Aluisio Rosa Gameiro Filho, Izadora Bouzeid Estacia da Silveira, Martina Estacia Da Cas, Rodrigo Rosa Gameiro

{"title":"Radius-Maumenee syndrome (idiopathic dilated episcleral vessels).","authors":"Carolina Tagliari Estacia, Aluisio Rosa Gameiro Filho, Izadora Bouzeid Estacia da Silveira, Martina Estacia Da Cas, Rodrigo Rosa Gameiro","doi":"10.3205/oc000247","DOIUrl":"10.3205/oc000247","url":null,"abstract":"Purpose: Idiopathic elevated episcleral venous pressure (IEEVP) or Radius-Maumenee syndrome (RMS) is a rare disease without any identified underlying cause. An increasing episcleral venous pressure (EVP) leads to raised intraocular pressure (IOP) and consequently glaucomatous damage of the optic nerve. The objective of this paper is to report this rare condition as well as its clinical management.Observations: During cataract evaluation a 38-year-old female patient referred to redness in her right eye that had started more than 3 years before. The IOP was 22 mmHg in her right eye and 14 mmHg in her left eye, although she was already using Timolol drops. Biomicroscopy revealed diffusely engorged episcleral vessels, without any other relevant findings. Intracranial magnetic resonance imaging (MRI) was normal. For that reason, the diagnosis of RMS was established. After 3 months, the patient remains in use of Timolol and Latanoprost eye drops, with intraocular pressure within normal levels. She continues to be followed up on a regular outpatient basis.Conclusions and significance: RMS is a diagnosis of exclusion, based on clinical findings and imaging exams. Treatment includes eyes drops and surgery in refractory cases.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc15"},"PeriodicalIF":0.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cancer-associated retinopathy secondary to gallbladder carcinoma. 继发于胆囊癌的癌症相关视网膜病变。

GMS ophthalmology cases Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3205/oc000243

Karel Goyvaerts, Tanja Coeckelbergh, Pieter-Paul Schauwvlieghe, Michel van Lint

{"title":"Cancer-associated retinopathy secondary to gallbladder carcinoma.","authors":"Karel Goyvaerts, Tanja Coeckelbergh, Pieter-Paul Schauwvlieghe, Michel van Lint","doi":"10.3205/oc000243","DOIUrl":"10.3205/oc000243","url":null,"abstract":"Objective: To present a rare case of cancer-associated retinopathy secondary to gallbladder carcinoma.Methods: Retrospective case report. Drugs used in case report: methylprednisolone (Medrol), CAS number: 83-43-2, producer: Pfizer; carboplatin, CAS number: 41575-94-4, producer: Accor; etoposide, CAS number: 33419-42-0, producer: Teva; methotrexate (Ledertrexate), CAS number: 59-05-2, producer: Pfizer.Results: A 57-year-old Moroccan man was referred with bilateral progressive vision loss in the last 4 months. At presentation, best corrected visual acuity (BCVA) was counting fingers for the right eye and 20/500 for the left eye. Examination demonstrated signs of vitritis, an electronegative full-field electroretinography (FF-ERG), ocular coherence tomography (OCT) abnormalities and multiple hyperautofluorescent round lesions on fundus autofluorescence imaging (FAF). The diagnosis of cancer-associated retinopathy (CAR) was considered, thus a positron emission tomography-computed tomography (PET-CT) was performed and revealed the presence of a metastasized gallbladder carcinoma. Additional fluorescence in situ hybridization (FISH) showed seropositivity for anti-retinal autoantibodies. High-dose corticosteroids together with anti-tumoral medication (carboplatin-etoposide) gradually improved the BCVA to 20/66 for the right eye and 20/20 for the left eye.Conclusions: Consider the diagnosis of CAR in patients with progressive concentric visual field loss, uveitis and fundus abnormalities, especially if bilateral. If CAR is suspected, perform a full work-up: FF-ERG, OCT, and whole-body PET-CT. In the treatment of CAR, immunosuppressives are mostly used, combined with antitumoral therapy. However, in the long-term, progressive visual loss is expected in most cases.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc11"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epithelial downgrowth masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-FU treatment. 伪装成肉芽肿性前葡萄膜炎和中葡萄膜炎的上皮细胞增生，组织病理学证据显示曾接受过 5-FU 治疗。

GMS ophthalmology cases Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3205/oc000245

Colin P Froines, Alexander D Lin, Kaivon Pakzad-Vaezi, Gordana Juric-Sekhar, Caitlin S Latimer, Kathryn P Scherpelz, C Dirk Keene, Eissa M Hanna, Michael R Banitt, Luis F Gonzalez-Cuyar

{"title":"Epithelial downgrowth masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-FU treatment.","authors":"Colin P Froines, Alexander D Lin, Kaivon Pakzad-Vaezi, Gordana Juric-Sekhar, Caitlin S Latimer, Kathryn P Scherpelz, C Dirk Keene, Eissa M Hanna, Michael R Banitt, Luis F Gonzalez-Cuyar","doi":"10.3205/oc000245","DOIUrl":"10.3205/oc000245","url":null,"abstract":"Purpose: Highlight an unusual case of epithelial downgrowth (EDG) masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-fluorouracil (5-FU) treatment.Case description: A 33-year-old man presented after multiple corneal surgeries and neodymium-doped yttrium aluminum garnet (Nd:YAG) capsulotomies with subacute angle closure, pain, light sensitivity, and decreased vision. Exam was notable for granulomatous keratic precipitates, an opacified lens capsule, and vitreous cell/haze. An anterior chamber paracentesis was sent for 16 s (pan-bacterial) and 28 s (pan-fungal) rRNA polymerase chain reaction testing, which returned negative. Diagnostic argon laser photocoagulation was performed on the iris and lens capsule, which blanched upon laser photocoagulation, and subsequent iris biopsy confirmed the presence of epithelial downgrowth (EDG). The patient was treated with multiple injections of 5-FU with repeat biopsy demonstrating both a reduction and apparent resolution in epithelial cell burden after 5-FU.Conclusion: This case demonstrates an unusual presentation of EDG in a young patient with granulomatous anterior and intermediate uveitis, where simple office-based procedures of Argon laser photocoagulation and anterior chamber paracentesis helped aid in diagnosis and management. Histopathological examination in serial specimens demonstrated the effect of 5-FU on EGD. To our knowledge, this case is the first to describe histopathological reduction in epithelial cell burden with sustained resolution.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc13"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pseudophakic corneal edema caused by Descemet membrane detachment using high-resolution swept-source OCT imaging. 利用高分辨率扫描源 OCT 成像，观察由 Descemet 膜脱落引起的假性角膜水肿。

GMS ophthalmology cases Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3205/oc000244

Maximilian K Köppe, Ramin Khoramnia, Gerd U Auffarth, Victor A Augustin

{"title":"Pseudophakic corneal edema caused by Descemet membrane detachment using high-resolution swept-source OCT imaging.","authors":"Maximilian K Köppe, Ramin Khoramnia, Gerd U Auffarth, Victor A Augustin","doi":"10.3205/oc000244","DOIUrl":"10.3205/oc000244","url":null,"abstract":"Background: Small Descemet membrane detachments after cataract surgery are relatively common and most cases do not require any secondary surgical intervention and can be treated conservatively. However, in case of advanced Descemet membrane detachment (DMD), it needs to be recognized and treated appropriately. The advent of anterior segment imaging using optical coherence tomography (OCT) technology has made diagnosing pathologies of the anterior segment accurate and time efficient and has proven as an invaluable tool to guide decision making.Case presentation: A 71-year-old patient presented after complicated cataract surgery with decreased visual acuity and cloudy vision. On examination, best corrected visual acuity was 1.5 logMAR. A high-resolution swept-source OCT (Anterion, Heidelberg Engineering, Heidelberg, Germany) was used to better evaluate and visualize the extent of DMD. An anterior chamber gas bubble was injected to reattach the Descemet membrane (DM) to the corneal stroma. The success of the surgery was visualized using the high-resolution swept-source OCT. This revealed a completely attached Descemet membrane.Conclusions: Clinically, it can be difficult to distinguish the etiology of epithelial and stromal edema post cataract surgery. This case demonstrated the clinical usefulness using high resolution swept source imaging to guide clinical decision making in evaluating timing and treatment success of pneumodescemetopexy after complicated cataract surgery.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc12"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse preretinal infiltrates in a patient with orbital atypical T-cell lymphoproliferative infiltration masquerading posterior uveitis. 一名伪装成后葡萄膜炎的眼眶非典型 T 细胞淋巴增生性浸润患者的弥漫性视网膜前浸润。

GMS ophthalmology cases Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3205/oc000242

Bilge Batu Oto, Oğuzhan Kılıçarslan, Didar Uçar, Samira Hagverdiyeva, Ahmet Murat Sarıcı

引用次数: 0

Combined use of intravitreal bevacizumab and oral steroid treatment in three diabetic papillopathy patients: a diagnostic and treatment challenge. 在三名糖尿病乳头状瘤病患者中联合使用玻璃体内贝伐单抗和口服类固醇治疗：诊断和治疗难题。

GMS ophthalmology cases Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI: 10.3205/oc000238

Burcu Taşkıran Kandeğer, Mehmet Argun, Levent Tök, Özlem Tök

引用次数: 0

Unilateral alacrimia as a presenting symptom of Meckel's cave tumour. 作为梅克尔洞穴瘤首发症状的单侧白细胞增多症。

GMS ophthalmology cases Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI: 10.3205/oc000241

Ignacio Manuel López Miñarro, Laura Prieto Domínguez, Víctor Manuel Asensio-Sánchez

引用次数: 0

A case of endogenous endophthalmitis caused by Escherichia coli septicemia. 一例由大肠杆菌败血症引起的内源性眼底病。

GMS ophthalmology cases Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI: 10.3205/oc000239

Tejinder Talwar, Prateek Chandra, Sugandha Goel, Kuntal Patel

引用次数: 0

Bilateral reversible optic neuropathy as the first sign of Waldenström macroglobulinema. 双侧可逆性视神经病变是瓦尔登斯特伦巨球蛋白症的首发症状。

GMS ophthalmology cases Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI: 10.3205/oc000240

Yoshiaki Shimada, Yoshiki Akatsuka, Kazuya Nokura

{"title":"Bilateral reversible optic neuropathy as the first sign of Waldenström macroglobulinema.","authors":"Yoshiaki Shimada, Yoshiki Akatsuka, Kazuya Nokura","doi":"10.3205/oc000240","DOIUrl":"10.3205/oc000240","url":null,"abstract":"Objective: To report a case of bilateral reversible optic neuropathy as the first sign of Waldenström macroglobulinemia (WM).Methods: Observational case report.Results: A 52-year-old man had a sudden loss of vision in the left eye. Examinations revealed the presence of a serum monoclonal immunoglobulin (IgM kappa) in the serum. Even after a session of steroid pulse therapy, optic neuropathy became bilateral and then resolved almost completely after 4 months. The condition progressed to WM with multiorgan lesions years later. There was no evidence of optic neuropathy recurrence. The literature revealed two cases of monoclonal gammopathy (MG): a 64-year-old man with multiple myeloma (MM) with IgA lambda and a 51-year-old man with MM with IgG kappa. These cases have similar conditions: 1) visual reduction as an initial symptom of MG, 2) bilateral involvement, 3) no sign of central nervous system (CNS) infiltration shown by normal brain magnetic resonance images, and 4) recovery to a visual acuity of ≥1.0 bilaterally with no reoccurrence. The excessive Igs or B-cell hyperactivity may activate an autoimmune mechanism that reversibly interferes with the bilateral optic nerves.Conclusion: Bilateral optic neuropathy was the initial symptom of WM. There was no evidence of CNS infiltration; it recovered and then did not reoccur. The pathogenesis remained unknown, but two cases of MG were reported in the literature with remarkably similar conditions.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc08"},"PeriodicalIF":0.0,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11238641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case report of bilateral Purtscher-like retinopathy in juvenile dermatomyositis. 一例罕见的幼年皮肌炎双侧珀切尔样视网膜病变报告。

GMS ophthalmology cases Pub Date : 2024-05-07 eCollection Date: 2024-01-01 DOI: 10.3205/oc000237

Nidhi Paharia, Shruti Agrawal, Nikhil Agrawal, Jayesh Shah

引用次数: 0