Diffuse preretinal infiltrates in a patient with orbital atypical T-cell lymphoproliferative infiltration masquerading posterior uveitis.

GMS ophthalmology cases Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI:10.3205/oc000242

Bilge Batu Oto, Oğuzhan Kılıçarslan, Didar Uçar, Samira Hagverdiyeva, Ahmet Murat Sarıcı

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Abstract

Purpose: To report an aggressive and rapidly progressive case of atypical T-cell lymphoproliferative infiltration both with intraocular and orbital involvement and preretinal infiltrates.

Methods: Medical records and imaging of the patient were retrospectively reviewed.

Case presentation: A 25-year-old woman presented first with preretinal infiltrates resembling uveitis and developed orbital and intracranial signs eventually during her evaluation. Clinical presentation worsened gradually. The patient developed bilateral proptosis, pupillary dilation and uvula deviation. Diagnostic orbital incision biopsy revealed T-cell lymphoproliferative disease.

Conclusion: This case gives evidence that intraocular involvement due to T-cell lymphoproliferative disease may present as a masquerade syndrome and should be kept in mind in patients with extraordinary presentation.

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一名伪装成后葡萄膜炎的眼眶非典型 T 细胞淋巴增生性浸润患者的弥漫性视网膜前浸润。

目的：报告一例侵袭性和快速进展的非典型T细胞淋巴细胞增生性浸润病例，该病例同时伴有眼内和眼眶受累以及视网膜前浸润：方法：回顾性分析患者的病历和影像学资料：一名 25 岁女性患者首先出现类似葡萄膜炎的视网膜前浸润，在评估期间最终出现眼眶和颅内症状。临床表现逐渐恶化。患者出现双侧眼球突出、瞳孔散大和悬雍垂。诊断性眼眶切口活检显示患者患有 T 细胞淋巴增生性疾病：本病例证明，T 细胞淋巴细胞增生性疾病导致的眼内受累可能表现为一种假性综合征，对于有特殊表现的患者应加以注意。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

GMS ophthalmology cases

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6 weeks