GMS ophthalmology cases最新文献

Same-side recurrence of unilateral multiple evanescent white dot syndrome following the thermal laser photocoagulation for inflammatory macular neovascularization. 热激光光凝治疗炎性黄斑新生血管后单侧多发消失性白点综合征的同侧复发。

GMS ophthalmology cases Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.3205/oc000250

Barbaros Hayrettin Ünlü, Omer Karti, Ayse Bozkurt Oflaz, Erk Atlay, Ali Osman Saatci

{"title":"Same-side recurrence of unilateral multiple evanescent white dot syndrome following the thermal laser photocoagulation for inflammatory macular neovascularization.","authors":"Barbaros Hayrettin Ünlü, Omer Karti, Ayse Bozkurt Oflaz, Erk Atlay, Ali Osman Saatci","doi":"10.3205/oc000250","DOIUrl":"10.3205/oc000250","url":null,"abstract":"Purpose: We report the same side recurrence of multiple evanescent white dot syndrome (MEWDS) subsequent to 532 nm laser treatment for the macular neovascularization (MNV) associated with the first MEWDS episode.Method: Retrospective case documentation with the multimodal imaging.Result: A 24-year-old otherwise healthy woman who was diagnosed as having left MEWDS four years ago was re-examined for a visual disturbance of the duration of one month in the same eye. Fundus evaluation led us to the diagnosis of left extrafoveal inflammatory MNV. Surprisingly, she developed further visual deterioration a month following the uneventful 532 nm laser photocoagulation in her left eye. Fundus examination and multimodal imaging tests confirmed the recurrent MEWDS after full negative laboratory work-up. Visual acuity and fundus changes were improved with the help of a short course oral steroid therapy.Conclusion: MEWDS can very rarely recur and thermal laser photocoagulation may be a possible triggering factor.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"15 ","pages":"Doc02"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Repeated deep anterior lamellar keratoplasty combined with phacoemulsification. 重复深前板层角膜移植术联合超声乳化术。

GMS ophthalmology cases Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.3205/oc000252

Mustafa Kayabaşı, Canan Asli Utine

{"title":"Repeated deep anterior lamellar keratoplasty combined with phacoemulsification.","authors":"Mustafa Kayabaşı, Canan Asli Utine","doi":"10.3205/oc000252","DOIUrl":"10.3205/oc000252","url":null,"abstract":"Objective: To report the clinical findings and results of a patient who underwent deep anterior lamellar keratoplasty (DALK) combined with phacoemulsification.Methods: Retrospective analysis of a case that underwent unsuccessful DALK surgery with no visual gain due to striations on the posterior surface of the donor, permanent interface irregularity, and scarring.Results: Two years after the first DALK surgery, a repeated DALK was performed in combination with phacoemulsification of the cataract that developed during this period. The graft was clear with no signs of rejection or endothelial decompensation, and corrected distance visual acuity was 6/10 in the postoperative last visit, one year after the surgery.Conclusions: Combining the DALK technique with phacoemulsification in patients with coexisting cataracts may help to achieve a good visual outcome and long-term graft survival. Even after an unsuccessful DALK experience, insisting on preserving the patient's own endothelium resulted in successful vision restoration with no imposition of further risks for graft survival.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"15 ","pages":"Doc04"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The m.3243A>G variant affects not only islet, hair, or retinal ganglion cells, but all cells. m.3243A >g变异不仅影响胰岛细胞、毛细胞或视网膜神经节细胞，而且影响所有细胞。

GMS ophthalmology cases Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.3205/oc000251

Josef Finsterer

引用次数: 0

Typical presentation of autosomal recessive oculocutaneous albinism in two siblings. 常染色体隐性遗传性眼皮肤白化病的典型表现在两个兄弟姐妹。

GMS ophthalmology cases Pub Date : 2025-04-10 eCollection Date: 2025-01-01 DOI: 10.3205/oc000249

Prateek Nishant, Naila Aftab, Bhawesh Saha, Amit Raj

{"title":"Typical presentation of autosomal recessive oculocutaneous albinism in two siblings.","authors":"Prateek Nishant, Naila Aftab, Bhawesh Saha, Amit Raj","doi":"10.3205/oc000249","DOIUrl":"10.3205/oc000249","url":null,"abstract":"Objective: We report the case history and clinical findings in two siblings, a 13-year-old male and a 10-year-old female, who presented with complaints of poor vision since childhood. Both children had blonde hair and depigmented skin.Methods: Ocular examination revealed white eyebrows, white eyelashes, diminished vision in all eyes, hypochromic irides and pendular nystagmus. On dilated fundus examination, hypopigmented fundi with conspicuously visible choroidal vessels were noted. No foveolar reflex could be discerned and spectral domain optical coherence tomography (SD-OCT) of the macula showed an absence of the foveal pit in all four eyes. On pedigree charting the subjects were the 2nd and 3rd offspring of a non-consanguineous married couple. One of the mother's siblings and one of the grandmother's siblings also had a similar disorder.Results: The poor definition of the foveal pit at the centre of the macula, i.e. foveal hypoplasia, accounted for poor visual acuity and nystagmus. Both cases had no syndromic associations. Spectacle correction was prescribed to both children, and low-vision aids and sun protection advised.Conclusion: Oculocutaneous albinism (OCA) represents a range of inherited, congenital disorders of hypomelanosis, involving the skin, hair, and eyes with an estimated prevalence of 1 in 17,000 cases. Affected children suffer severe visual disability while early identification may potentially mitigate it, hence there is need to sensitize primary care practitioners regarding the general symptoms of OCA.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"15 ","pages":"Doc01"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adie's pupil and systemic manifestations: a rare unilateral presentation. 爱迪氏瞳孔及全身表现：罕见的单侧表现。

GMS ophthalmology cases Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3205/oc000246

M N Vimisha, M Shah Virna, Kumar Karthik, R Sharanya

引用次数: 0

Transient anterior chamber intraocular lens opacification by triamcinolone acetonide following intravitreal injection. 玻璃体注射曲安奈德致短暂性前房人工晶状体混浊。

GMS ophthalmology cases Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3205/oc000248

Kshitiz Kumar, Deepak Agarwal, Aditya Bajaj, Subrata Saha

{"title":"Transient anterior chamber intraocular lens opacification by triamcinolone acetonide following intravitreal injection.","authors":"Kshitiz Kumar, Deepak Agarwal, Aditya Bajaj, Subrata Saha","doi":"10.3205/oc000248","DOIUrl":"10.3205/oc000248","url":null,"abstract":"Background: Pseudophakic cystoid macular edema (CME) following primary anterior-chamber intraocular lens (ACIOL) implantations is commonly seen. Intravitreal triamcinolone acetonide (IVTA) injections have shown significant improvement in visual acuity and retinal thickness in refractory pseudophakic CME. Pseudohypopyon following IVTA injection is a known entity.Objective: To report a rare complication of transient acute vision loss due to ACIOL coating with triamcinolone acetonide particles following intravitreal injection.Methods: Case study.Results: A patient developed pseudophakic cystoid macular edema two months post complicated cataract operation with ACIOL implantation. Despite topical steroid treatment, CME persisted and the patient was administered intravitreal triamcinolone acetonide injection. Acute vision loss due to dense coating of ACIOL with triamcinolone particles was noted on the next day. Conservative management led to spontaneous clearing of intraocular lens (IOL) and resolution of CME in 4 weeks.Conclusions: Opacification of ACIOL following IVTA injection is a rare complication which can be seen in eyes with compromised zonular/capsular bag integrity.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc16"},"PeriodicalIF":0.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radius-Maumenee syndrome (idiopathic dilated episcleral vessels). Radius-Maumenee综合征（特发性外膜血管扩张）。

GMS ophthalmology cases Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.3205/oc000247

Carolina Tagliari Estacia, Aluisio Rosa Gameiro Filho, Izadora Bouzeid Estacia da Silveira, Martina Estacia Da Cas, Rodrigo Rosa Gameiro

{"title":"Radius-Maumenee syndrome (idiopathic dilated episcleral vessels).","authors":"Carolina Tagliari Estacia, Aluisio Rosa Gameiro Filho, Izadora Bouzeid Estacia da Silveira, Martina Estacia Da Cas, Rodrigo Rosa Gameiro","doi":"10.3205/oc000247","DOIUrl":"10.3205/oc000247","url":null,"abstract":"Purpose: Idiopathic elevated episcleral venous pressure (IEEVP) or Radius-Maumenee syndrome (RMS) is a rare disease without any identified underlying cause. An increasing episcleral venous pressure (EVP) leads to raised intraocular pressure (IOP) and consequently glaucomatous damage of the optic nerve. The objective of this paper is to report this rare condition as well as its clinical management.Observations: During cataract evaluation a 38-year-old female patient referred to redness in her right eye that had started more than 3 years before. The IOP was 22 mmHg in her right eye and 14 mmHg in her left eye, although she was already using Timolol drops. Biomicroscopy revealed diffusely engorged episcleral vessels, without any other relevant findings. Intracranial magnetic resonance imaging (MRI) was normal. For that reason, the diagnosis of RMS was established. After 3 months, the patient remains in use of Timolol and Latanoprost eye drops, with intraocular pressure within normal levels. She continues to be followed up on a regular outpatient basis.Conclusions and significance: RMS is a diagnosis of exclusion, based on clinical findings and imaging exams. Treatment includes eyes drops and surgery in refractory cases.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc15"},"PeriodicalIF":0.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cancer-associated retinopathy secondary to gallbladder carcinoma. 继发于胆囊癌的癌症相关视网膜病变。

GMS ophthalmology cases Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3205/oc000243

Karel Goyvaerts, Tanja Coeckelbergh, Pieter-Paul Schauwvlieghe, Michel van Lint

{"title":"Cancer-associated retinopathy secondary to gallbladder carcinoma.","authors":"Karel Goyvaerts, Tanja Coeckelbergh, Pieter-Paul Schauwvlieghe, Michel van Lint","doi":"10.3205/oc000243","DOIUrl":"10.3205/oc000243","url":null,"abstract":"Objective: To present a rare case of cancer-associated retinopathy secondary to gallbladder carcinoma.Methods: Retrospective case report. Drugs used in case report: methylprednisolone (Medrol), CAS number: 83-43-2, producer: Pfizer; carboplatin, CAS number: 41575-94-4, producer: Accor; etoposide, CAS number: 33419-42-0, producer: Teva; methotrexate (Ledertrexate), CAS number: 59-05-2, producer: Pfizer.Results: A 57-year-old Moroccan man was referred with bilateral progressive vision loss in the last 4 months. At presentation, best corrected visual acuity (BCVA) was counting fingers for the right eye and 20/500 for the left eye. Examination demonstrated signs of vitritis, an electronegative full-field electroretinography (FF-ERG), ocular coherence tomography (OCT) abnormalities and multiple hyperautofluorescent round lesions on fundus autofluorescence imaging (FAF). The diagnosis of cancer-associated retinopathy (CAR) was considered, thus a positron emission tomography-computed tomography (PET-CT) was performed and revealed the presence of a metastasized gallbladder carcinoma. Additional fluorescence in situ hybridization (FISH) showed seropositivity for anti-retinal autoantibodies. High-dose corticosteroids together with anti-tumoral medication (carboplatin-etoposide) gradually improved the BCVA to 20/66 for the right eye and 20/20 for the left eye.Conclusions: Consider the diagnosis of CAR in patients with progressive concentric visual field loss, uveitis and fundus abnormalities, especially if bilateral. If CAR is suspected, perform a full work-up: FF-ERG, OCT, and whole-body PET-CT. In the treatment of CAR, immunosuppressives are mostly used, combined with antitumoral therapy. However, in the long-term, progressive visual loss is expected in most cases.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc11"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epithelial downgrowth masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-FU treatment. 伪装成肉芽肿性前葡萄膜炎和中葡萄膜炎的上皮细胞增生，组织病理学证据显示曾接受过 5-FU 治疗。

GMS ophthalmology cases Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3205/oc000245

Colin P Froines, Alexander D Lin, Kaivon Pakzad-Vaezi, Gordana Juric-Sekhar, Caitlin S Latimer, Kathryn P Scherpelz, C Dirk Keene, Eissa M Hanna, Michael R Banitt, Luis F Gonzalez-Cuyar

{"title":"Epithelial downgrowth masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-FU treatment.","authors":"Colin P Froines, Alexander D Lin, Kaivon Pakzad-Vaezi, Gordana Juric-Sekhar, Caitlin S Latimer, Kathryn P Scherpelz, C Dirk Keene, Eissa M Hanna, Michael R Banitt, Luis F Gonzalez-Cuyar","doi":"10.3205/oc000245","DOIUrl":"10.3205/oc000245","url":null,"abstract":"Purpose: Highlight an unusual case of epithelial downgrowth (EDG) masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-fluorouracil (5-FU) treatment.Case description: A 33-year-old man presented after multiple corneal surgeries and neodymium-doped yttrium aluminum garnet (Nd:YAG) capsulotomies with subacute angle closure, pain, light sensitivity, and decreased vision. Exam was notable for granulomatous keratic precipitates, an opacified lens capsule, and vitreous cell/haze. An anterior chamber paracentesis was sent for 16 s (pan-bacterial) and 28 s (pan-fungal) rRNA polymerase chain reaction testing, which returned negative. Diagnostic argon laser photocoagulation was performed on the iris and lens capsule, which blanched upon laser photocoagulation, and subsequent iris biopsy confirmed the presence of epithelial downgrowth (EDG). The patient was treated with multiple injections of 5-FU with repeat biopsy demonstrating both a reduction and apparent resolution in epithelial cell burden after 5-FU.Conclusion: This case demonstrates an unusual presentation of EDG in a young patient with granulomatous anterior and intermediate uveitis, where simple office-based procedures of Argon laser photocoagulation and anterior chamber paracentesis helped aid in diagnosis and management. Histopathological examination in serial specimens demonstrated the effect of 5-FU on EGD. To our knowledge, this case is the first to describe histopathological reduction in epithelial cell burden with sustained resolution.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc13"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pseudophakic corneal edema caused by Descemet membrane detachment using high-resolution swept-source OCT imaging. 利用高分辨率扫描源 OCT 成像，观察由 Descemet 膜脱落引起的假性角膜水肿。

GMS ophthalmology cases Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3205/oc000244

Maximilian K Köppe, Ramin Khoramnia, Gerd U Auffarth, Victor A Augustin

{"title":"Pseudophakic corneal edema caused by Descemet membrane detachment using high-resolution swept-source OCT imaging.","authors":"Maximilian K Köppe, Ramin Khoramnia, Gerd U Auffarth, Victor A Augustin","doi":"10.3205/oc000244","DOIUrl":"10.3205/oc000244","url":null,"abstract":"Background: Small Descemet membrane detachments after cataract surgery are relatively common and most cases do not require any secondary surgical intervention and can be treated conservatively. However, in case of advanced Descemet membrane detachment (DMD), it needs to be recognized and treated appropriately. The advent of anterior segment imaging using optical coherence tomography (OCT) technology has made diagnosing pathologies of the anterior segment accurate and time efficient and has proven as an invaluable tool to guide decision making.Case presentation: A 71-year-old patient presented after complicated cataract surgery with decreased visual acuity and cloudy vision. On examination, best corrected visual acuity was 1.5 logMAR. A high-resolution swept-source OCT (Anterion, Heidelberg Engineering, Heidelberg, Germany) was used to better evaluate and visualize the extent of DMD. An anterior chamber gas bubble was injected to reattach the Descemet membrane (DM) to the corneal stroma. The success of the surgery was visualized using the high-resolution swept-source OCT. This revealed a completely attached Descemet membrane.Conclusions: Clinically, it can be difficult to distinguish the etiology of epithelial and stromal edema post cataract surgery. This case demonstrated the clinical usefulness using high resolution swept source imaging to guide clinical decision making in evaluating timing and treatment success of pneumodescemetopexy after complicated cataract surgery.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"14 ","pages":"Doc12"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0