{"title":"Orbito-sinal foreign body with floor fracture: an unusual presentation.","authors":"Narendra Patidar, Saket Agrawal, Rukmendra Pratap Singh, Prerana Phadnis","doi":"10.3205/oc000159","DOIUrl":"https://doi.org/10.3205/oc000159","url":null,"abstract":"<p><p>Wooden foreign bodies penetrating through the orbit into paranasal sinuses are rare. We report a case of a young male who complained of double vision, pain and redness after a fall from a tree. There was no external wound over periocular skin. The clinical and radiological examination was suggestive of an inferior orbito-sinal wooden foreign body with floor fracture, which was managed by surgical removal of the foreign body and orbital floor fracture repair using a silicon sheet in a single sitting.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc32"},"PeriodicalIF":0.0,"publicationDate":"2020-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38343841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GMS ophthalmology casesPub Date : 2020-08-06eCollection Date: 2020-01-01DOI: 10.3205/oc000161
Mona Bischoff-Jung, Elias Flockerzi, Andrea Hasenfus, Arne Viestenz, Pinio Matoula, Ursula Schlötzer-Schrehardt, Berthold Seitz
{"title":"Recurrence of macular corneal dystrophy on the graft 50 years after penetrating keratoplasty.","authors":"Mona Bischoff-Jung, Elias Flockerzi, Andrea Hasenfus, Arne Viestenz, Pinio Matoula, Ursula Schlötzer-Schrehardt, Berthold Seitz","doi":"10.3205/oc000161","DOIUrl":"https://doi.org/10.3205/oc000161","url":null,"abstract":"<p><p><b>Purpose:</b> To report the recurrence of a macular corneal stromal dystrophy 50 years after penetrating keratoplasty (PKP). <b>Methods:</b> Observational case report <b>Case</b> <b>description:</b> A 76-year-old male patient presented with visual impairment in the right eye (OD) 50 years after PKP in 1962 (44 years after PKP also in the left eye (OS) in 1968) following explosion injury. His visual acuity had already been impaired before the trauma because of bilateral corneal opacities. The central corneal thickness of the graft measured 584 µm (OD) and 544 µm (OS), whilst the peripheral host thickness (8 mm zone), however, was 1233 µm (OD, cranial) and 1131 µm (OS, nasal). The original graft diameter measured 6 mm in both eyes and the recipient cornea was cloudy and gray. The endothelial cell count was measured centrally (OD 1162 c/mm<sup>2</sup>, OS 1320 c/mm<sup>2</sup>). The visual acuity was 20/100 (OD) and 20/40 (OS). After excimerlaser-assisted repeated PKP (8.0/8.1 mm, OD), the histological analysis of the former graft revealed deposits of acid mucopolysaccharides (AMP) subepithelially, within the interface, in the donor stroma, and in the endothelium, which proved the peripheral recurrence of a macular corneal stromal dystrophy on the graft. <b>Conclusion:</b> Recurrence of macular corneal stromal dystrophy is seldom, but it may occur many decades after PKP. In this patient, the host's stroma was twice as thick as that of the graft. This may be caused by the active production of acid mucopolysaccharides in the host endothelium with secondary endothelial decompensation. Thus, PKP remains the gold standard in the cure of macular corneal dystrophy for long-term visual rehabilitation.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc34"},"PeriodicalIF":0.0,"publicationDate":"2020-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38343843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GMS ophthalmology casesPub Date : 2020-06-29eCollection Date: 2020-01-01DOI: 10.3205/oc000155
Virna M Shah, Ratnesh Ranjan, Mrunmayi Jeste, Peter MacIntosh, Duraiswamy Ashwath
{"title":"Bilateral vertical gaze palsy due to midbrain infarct associated with iron deficiency anemia in a young boy.","authors":"Virna M Shah, Ratnesh Ranjan, Mrunmayi Jeste, Peter MacIntosh, Duraiswamy Ashwath","doi":"10.3205/oc000155","DOIUrl":"https://doi.org/10.3205/oc000155","url":null,"abstract":"<p><p>An 8-year-old boy presented with complaints of sudden-onset binocular vertical diplopia of one day duration. Ophthalmic examination showed restricted up- and downgaze movement with rotatory nystagmus. Systemic investigations revealed iron-deficiency anemia and localized acute infarct in the left paramedian rostral and dorsal part of the upper midbrain at the level of the red nucleus on magnetic resonance imaging. The patient was started on oral iron supplement, which resulted in symptomatic as well as clinical improvement after 2 weeks.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc28"},"PeriodicalIF":0.0,"publicationDate":"2020-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38161860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mirtazapine-induced bilateral secondary angle closure in a female.","authors":"Srishti Raj, Manpreet Kaur, Kandragunta Srinivasarao, Faisal Thattaruthody, Sushmita Kaushik, Surinder Singh Pandav","doi":"10.3205/oc000156","DOIUrl":"https://doi.org/10.3205/oc000156","url":null,"abstract":"<p><p><b>Purpose:</b> To report a case of bilateral secondary angle closure in a female using mirtazapine for 6 months. <b>Patient and method:</b> A 55-year-old female was diagnosed with secondary angle closure in both eyes with raised intraocular pressure, and ultrasound biomicroscopic findings suggestive of ciliary body effusion. It was associated with adjoining cyst presumably because of the use of mirtazapine for depression and sleep disturbances. <b>Results:</b> After the planned discontinuation of mirtazapine, the ocular angle opened, the ciliary body edema decreased, and the cyst regressed in size. The intraocular pressure was controlled with topical timolol (0.5%). <b>Conclusion:</b> Patients with risk factors for angle closure should be prescribed antipsychotic drugs with caution. The peripheral laser iridotomy is not indicated in secondary angle closure due to ciliary body effusion.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc29"},"PeriodicalIF":0.0,"publicationDate":"2020-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38161861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inverted temporal internal limiting membrane flap technique for chronic large traumatic macular hole.","authors":"Archana Kumari, Lalit Agarwal, Nisha Agrawal, Sabin Sahu, Indranath Prasad, Deepti Pradhan","doi":"10.3205/oc000154","DOIUrl":"https://doi.org/10.3205/oc000154","url":null,"abstract":"<p><p>Various modifications of surgical techniques and surgical adjuncts are adopted with standard pars plana vitrectomy (PPV) to improve the outcome of traumatic macular hole (TMH) surgeries. We describe a successful closure of a chronic large TMH of three years duration with inverted temporal internal limiting membrane (ILM) flap technique. A 36-year-old male patient had an optical coherence tomography (OCT) documented chronic macular hole (MH) for three years following blunt trauma. Fundus examination also showed choroidal rupture scar temporal to fovea. The minimum MH diameter was 769 µ and the basal diameter 1431 µ in OCT. Standard PPV with inverted temporal ILM flap and gas tamponade was done. The postoperative period was uneventful. The best corrected visual acuity improved from 6/60 preoperatively to 6/18 six months postoperatively, and OCT showed a closed MH with anatomical type 1 closure. This case highlights that the inverted temporal ILM flap technique is a safe and effective technique for patients with even chronic and large TMH.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc27"},"PeriodicalIF":0.0,"publicationDate":"2020-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38161859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GMS ophthalmology casesPub Date : 2020-05-04eCollection Date: 2020-01-01DOI: 10.3205/oc000153
Giuseppe Casalino, Stefano Erba, Vasuki Sivagnanavel, Shervin Lari, Antonio Scialdone, Carlos Pavesio
{"title":"Spontaneous resolution of acute syphilitic posterior placoid chorioretinitis: reappraisal of the literature and pathogenetic insights.","authors":"Giuseppe Casalino, Stefano Erba, Vasuki Sivagnanavel, Shervin Lari, Antonio Scialdone, Carlos Pavesio","doi":"10.3205/oc000153","DOIUrl":"https://doi.org/10.3205/oc000153","url":null,"abstract":"<p><p>Acute syphilitic posterior placoid chorioretinitis (ASPPC) is a rare clinical manifestation of ocular syphilis. Spontaneous resolution of this condition has been reported in a few cases. The aim of this manuscript is to report an additional case and to discuss the possible pathogenesis of this condition by reviewing the current evidence on this subject. A 45-year-old man presented to us with decreased vision in the right eye secondary to a placoid macular lesion. Fourteen days after presentation, there was a dramatic improvement of the vision, and multimodal retinal imaging showed almost complete spontaneous resolution of the placoid lesion. Syphilis serology turned out positive and a diagnosis of ASPPC was made. The pathogenesis of ASPPC is unclear, and there is contrasting evidence about the role of the cellular immune system. Since this condition may resolve spontaneously before systemic antimicrobial treatment, the presence of a placoid macular lesion should raise a high suspicion of ASPPC in order to make a timely diagnosis and to avoid progression of untreated syphilis.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc26"},"PeriodicalIF":0.0,"publicationDate":"2020-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38161858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GMS ophthalmology casesPub Date : 2020-05-04eCollection Date: 2020-01-01DOI: 10.3205/oc000152
Corrina P Azarcon, Darby E Santiago
{"title":"Prolonged central nervous system and respiratory depression in preterm neonates after exposure to brimonidine tartrate and timolol maleate ophthalmic drops.","authors":"Corrina P Azarcon, Darby E Santiago","doi":"10.3205/oc000152","DOIUrl":"https://doi.org/10.3205/oc000152","url":null,"abstract":"<p><p><b>Objective:</b> We report three cases of preterm neonates who presented with central nervous system (CNS) and respiratory depression after inadvertent exposure to brimonidine tartrate 0.2% and timolol maleate 0.5% fixed-combination ophthalmic drops. <b>Case descriptions:</b> CNS and respiratory depression were observed in the three neonates within two hours of administration of brimonidine tartrate 0.2% and timolol maleate 0.5% eye drops. Respiratory support was initiated upon admission to the neonatal intensive care unit (NICU). The effects of the drug combination lasted for 24 to 48 hours. <b>Conclusion:</b> This case series suggests that the drug combination of brimonidine tartrate and timolol maleate causes a prolonged depression of the central nervous and respiratory systems in preterm neonates.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc25"},"PeriodicalIF":0.0,"publicationDate":"2020-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38161961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GMS ophthalmology casesPub Date : 2020-04-22eCollection Date: 2020-01-01DOI: 10.3205/oc000151
Hedwig Sillen, Joke Ruys, Pieter-Paul Schauwvlieghe, Marc Veckeneer
{"title":"Autologous full-thickness RPE-choroid graft to treat high-risk drusenoid pigment epithelial detachment without CNV.","authors":"Hedwig Sillen, Joke Ruys, Pieter-Paul Schauwvlieghe, Marc Veckeneer","doi":"10.3205/oc000151","DOIUrl":"https://doi.org/10.3205/oc000151","url":null,"abstract":"<p><p><b>Objective:</b> To report on the survival of a retinal pigment epithelium (RPE)-choroid graft translocated to treat a patient with drusenoid pigment epithelial detachment (DPED). <b>Methods:</b> We describe a patient with bilateral high-risk DPED where one eye was treated with RPE-choroid translocation surgery and followed up for more than two years. <b>Results:</b> The RPE-choroid graft surgery was straightforward and the fully perfused graft was able to support stable vision of 0.5 Snellen acuity for more than two years despite the development of a choroidal neovessel at the edge of the graft. The vision in the fellow eye dropped from 0.5 to 0.2 Snellen in the same period. <b>Conclusion:</b> RPE-choroid translocation may slow the progression of DPED to atrophy but it can also transform dry age-related macular degeneration (AMD) into neovascular AMD.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc24"},"PeriodicalIF":0.0,"publicationDate":"2020-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38161960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GMS ophthalmology casesPub Date : 2020-04-17eCollection Date: 2020-01-01DOI: 10.3205/oc000150
Sefik Can Ipek, Ziya Ayhan, Sinan Emre, Ali Osman Saatci
{"title":"Favorable clinical outcome with intravitreal aflibercept treatment in a case with bilateral choroidal neovascular membrane and quiescent Vogt-Koyanagi-Harada syndrome.","authors":"Sefik Can Ipek, Ziya Ayhan, Sinan Emre, Ali Osman Saatci","doi":"10.3205/oc000150","DOIUrl":"https://doi.org/10.3205/oc000150","url":null,"abstract":"<p><p><b>Objective:</b> To describe the favorable clinical outcome in a case with bilateral choroidal neovascular membrane and quiescent Vogt-Koyanagi-Harada (VKH) syndrome by administering bilateral intravitreal aflibercept injections. <b>Case report:</b> A 30-year-old woman was diagnosed with VKH syndrome at another institution and had been in remission with oral mycophenolate mofetil for two years. However, nearly simultaneous right juxtafoveal and left subfoveal type 2 choroidal neovascular membrane was detected two years after the initial diagnosis. The right eye (OD) received three and the left eye (OS) received four aflibercept injections within a time span of eight months. Visual acuity was 20/30 in OD and 20/25 in OS at the last follow-up visit. <b>Conclusion:</b> Although suppression of inflammation is a must in eyes with inflammatory type choroidal neovascular membranes, anti-VEGF (vascular endothelial growth factor) therapy with agents, such as aflibercept in the present case, is a key therapeutic adjunct and may possibly help improve the visual prognosis.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc23"},"PeriodicalIF":0.0,"publicationDate":"2020-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38161959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GMS ophthalmology casesPub Date : 2020-04-15eCollection Date: 2020-01-01DOI: 10.3205/oc000149
Sneha Padidam, Hamilton Trinh, Xihui Lin, Joseph D Boss
{"title":"Nonsurgical management of photoaversive ocular and systemic loiasis in Michigan.","authors":"Sneha Padidam, Hamilton Trinh, Xihui Lin, Joseph D Boss","doi":"10.3205/oc000149","DOIUrl":"https://doi.org/10.3205/oc000149","url":null,"abstract":"<p><p><b>Objective:</b> Ocular loasis refers to ocular conditions such as pain and redness caused by the movement of the <i>Loa loa</i> nematode through the subconjuctival space of the eye. It is a tropical disease that is very rarely seen in North America. We report the case of a 32-year-old male who was recently diagnosed with ocular loasis in the Midwestern region of the United States. <b>Methods:</b> He presented to the emergency department with left eye pain after seeing a \"worm in his eye\" the previous night. He had emigrated from Cameroon 7 years prior. Anterior segment examination revealed a translucent, motile worm in the subconjunctival space of his left eye. <b>Results:</b> Prior to the patient's scheduled follow-up for surgical removal of the worm, it migrated into the lower eyelid subdermal space. Serum testing confirmed the presence of <i>Loa loa</i> microfilariae at a concentration of >17,000 mf/mL. <b>Conclusion:</b> The patient was treated at the National Institute of Health (NIH) with pheresis followed by diethylcarbamazine and reported symptomatic improvement 1 month after treatment. This case report demonstrates the importance of being able to recognize and properly manage vector-borne parasites in nonendemic areas due to increased travel and climate change.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"10 ","pages":"Doc22"},"PeriodicalIF":0.0,"publicationDate":"2020-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38161958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}