Combined use of intravitreal bevacizumab and oral steroid treatment in three diabetic papillopathy patients: a diagnostic and treatment challenge.

GMS ophthalmology cases Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI:10.3205/oc000238
Burcu Taşkıran Kandeğer, Mehmet Argun, Levent Tök, Özlem Tök
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Abstract

Diabetic papillopathy (DP), a form of optic disc edema, is characterized by decreased visual acuity and mild to severe visual field defects. While there is no consensus about treatment, some publications report that intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection may be beneficial. To our knowledge, however, no research reports on the effects of combining anti-VEGF injection and oral steroids in DP treatment. In this case report we present three DP cases that showed rapid improvement following therapy with intravitreal bevacizumab and oral steroids. Optic disc edemas were significantly decreased, and visual acuities were markedly increased in the first week of treatment. This report suggests that combined use of these therapies may be safely used in patients diagnosed with DP.

在三名糖尿病乳头状瘤病患者中联合使用玻璃体内贝伐单抗和口服类固醇治疗:诊断和治疗难题。
糖尿病乳头状病变(DP)是视盘水肿的一种形式,其特征是视力下降和轻度至重度视野缺损。虽然对治疗方法还没有达成共识,但一些出版物报道说,玻璃体内注射抗血管内皮生长因子(anti-VEGF)可能有益。然而,据我们所知,目前还没有研究报告称,抗血管内皮生长因子注射和口服类固醇联合应用于DP的治疗效果如何。在本病例报告中,我们介绍了三例在接受玻璃体内贝伐单抗和口服类固醇治疗后病情迅速好转的 DP 病例。在治疗的第一周,视盘水肿明显减轻,视力明显提高。该报告表明,联合使用这些疗法可安全地用于确诊的 DP 患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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