GMS ophthalmology cases最新文献_第3页

Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumor. 局灶性反应性结节性胶质瘤：一种极其罕见的视网膜星形胶质瘤。

GMS ophthalmology cases Pub Date : 2023-12-12 eCollection Date: 2023-01-01 DOI: 10.3205/oc000230

Saúl Villoria-Díaz, María Antonia Saornil-Álvarez, Ciro García-Álvarez, Elena García-Lagarto, Irene Bermúdez-Castellanos

引用次数: 0

Infliximab-induced retrobulbar optic neuritis in a patient with ankylosing spondylitis. 一名强直性脊柱炎患者因使用英夫利西单抗引发球后视神经炎。

GMS ophthalmology cases Pub Date : 2023-12-12 eCollection Date: 2023-01-01 DOI: 10.3205/oc000232

Sema Dündar, Mimbay Yaşar, Harun Çakmak, Nefati Kıylıoğlu, Alparslan Ünsal

{"title":"Infliximab-induced retrobulbar optic neuritis in a patient with ankylosing spondylitis.","authors":"Sema Dündar, Mimbay Yaşar, Harun Çakmak, Nefati Kıylıoğlu, Alparslan Ünsal","doi":"10.3205/oc000232","DOIUrl":"https://doi.org/10.3205/oc000232","url":null,"abstract":"Objective: To present a case with infliximab-induced retrobulbar optic neuritis.Case description: A 58-year-old woman presented to our clinic with a two-day history of blurred vision in her right eye. She had numerous uveitis attacks previously, and she was on infliximab treatment for ankylosing spondylitis. Her best-corrected visual acuity was counting fingers and 20/25 in the right and left eye, respectively. Optic discs seemed healthy in fundoscopic examination. The right optic nerve showed high signal intensity on magnetic resonance imaging (MRI). Infliximab treatment was discontinued and systemic steroid therapy was started. After the treatment her best-corrected visual acuity improved to 20/20 in her right eye.Conclusion: Infliximab is a chimeric human-murine monoclonal antibody used in autoimmune diseases. Optic neuritis is a rare but important side effect of infliximab. Thus, infliximab-induced optic neuritis should be kept in mind for patients receiving infliximab treatment.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc24"},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10726561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138814656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multimodal analysis in symptomatic MIDD-associated retinopathy. A case report and literature review. 有症状的 MIDD 相关视网膜病变的多模态分析。病例报告和文献综述。

GMS ophthalmology cases Pub Date : 2023-12-12 eCollection Date: 2023-01-01 DOI: 10.3205/oc000231

Katarzyna Chwiejczak, Daniel Byles, Paul Gerry, Hirut Von Lany, Anastasia Tasiopoulou, Andrew Hattersley

{"title":"Multimodal analysis in symptomatic MIDD-associated retinopathy. A case report and literature review.","authors":"Katarzyna Chwiejczak, Daniel Byles, Paul Gerry, Hirut Von Lany, Anastasia Tasiopoulou, Andrew Hattersley","doi":"10.3205/oc000231","DOIUrl":"https://doi.org/10.3205/oc000231","url":null,"abstract":"Purpose: To present results of contemporary multimodal ophthalmic imaging in a case of maternally inherited diabetes and deafness (MIDD) and a literature review of MIDD.Methods: A case of a 47-year-old female with diabetes mellitus, severe insulin resistance, familial lipodystrohy, deafness and increasing problems with vision is reported. A full ophthalmic examination was done, including best corrected visual acuity (BCVA, LogMAR), funduscopy, and imaging studies: optical coherence tomography (OCT), OCT angiography (OCT-A), fundus autofloresence (FAF), visual fields (HVF) 10-2 , electrophysiology (EP) and genetic testing were performed. Literature available on the topic was reviewed.Results: BCVA was 0.06 LogMAR in the right eye and 0.1 LogMAR in the left. Funduscopy revealed atrophy (AT) and pigmentary changes but no diabetic retinopathy. HVF confirmed corresponding defects. The imaging and diagnostic tests showed the following abnormalities: FAF: hypoautofluoresence in areas of AT and mottled appearance in the macular and peripapillary area; OCT: attenuation of outer retinal layers and retinal pigment epithelium (RPE) in the AT; OCT-A: thinning of the deep capillary plexus and choriocapillaris; EP: abnormalities on full field electroretinogram (ERG), 30 Hz flicker and single cone flash response; multifocal ERG: reduced responses; genetic testing: A-to-G transition mutation at position 3243 of the mitochondrial genome, typical for MIDD. After one year OCT ganglion cell analysis showed loss of thickness.Conclusions: Genetic testing should be considered in diabetic patients with pigmentary retinopathy. Imaging studies and diagnostic testing showed structural and functional retinal changes, confined to the macula and progressive in nature.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc23"},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10726563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138814657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare presentation of a common carotid artery occlusion. 颈总动脉闭塞的罕见表现。

GMS ophthalmology cases Pub Date : 2023-11-07 eCollection Date: 2023-01-01 DOI: 10.3205/oc000228

Amber Demeuleneere, Julie Lambert, Jelle Demeestere, Robin Lemmens, Inge Fourneau, Sabrina Houthoofd, Pieter-Paul Schauwvlieghe, Julie Jacob, Catherine Cassiman

{"title":"A rare presentation of a common carotid artery occlusion.","authors":"Amber Demeuleneere, Julie Lambert, Jelle Demeestere, Robin Lemmens, Inge Fourneau, Sabrina Houthoofd, Pieter-Paul Schauwvlieghe, Julie Jacob, Catherine Cassiman","doi":"10.3205/oc000228","DOIUrl":"https://doi.org/10.3205/oc000228","url":null,"abstract":"Background: A common carotid artery occlusion (CCAO) is very rare and the clinical features of CCAO have rarely been described. Since the blood supply of the eye and orbit is derived from the internal carotid artery, a CCAO may present with various ophthalmological symptoms, ranging from incidental findings to complete visual loss but also other neuro-ophthalmological abnormalities.Case report: A 61-year-old woman presented with acute monocular vision loss and an elevation deficit of the right eye. Fluorescein angiography showed delayed filling of both the retinal and choroidal vasculature, without occlusion/embolisms of the retinal arteries. Vascular imaging showed a right CCAO.Conclusion: CCAO has a variable presentation. In patients with acute unilateral visual loss a CCAO should be considered, especially when ocular motility deficits are present. Fluorescein angiography examination can aid in the localization and diagnosis of the vascular insult. Urgent referral for a systemic work-up is essential.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc20"},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10726582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138814645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent multiple eye muscle palsy as a first sign of sarcoidosis. 复发性多发性眼肌麻痹是肉瘤病的首发症状。

GMS ophthalmology cases Pub Date : 2023-11-07 eCollection Date: 2023-01-01 DOI: 10.3205/oc000229

Isabel Deboutte, Daisy Godts, Michel Van Lint

{"title":"Recurrent multiple eye muscle palsy as a first sign of sarcoidosis.","authors":"Isabel Deboutte, Daisy Godts, Michel Van Lint","doi":"10.3205/oc000229","DOIUrl":"https://doi.org/10.3205/oc000229","url":null,"abstract":"Purpose: To report a case of (neuro)sarcoidosis presenting solely with recurrent cranial nerve palsies in a 57-year-old Caucasian female.Methods: Case report with clinical imaging.Results: A 57-year-old female first presented with a right sixth nerve palsy, which resolved spontaneously after 6 months. Three years later she was diagnosed with a sixth nerve palsy in the fellow eye followed by a complete palsy of the left third cranial nerve four months after. Medical history consisted of migraine and hypercholesterolemia. Further neurological and ophthalmic work-up was unrevealing at first. After repeated magnetic resonance imaging, an enhancing lesion in the left cavernous sinus was seen, which was initially diagnosed as a meningioma. However, imaging of the chest revealed an image of sarcoidosis, and the lesion and ophthalmoplegia of the left eye disappeared with systemic corticosteroid treatment.Discussion: Sarcoidosis is the ultimate imitator and the possibility of neurosarcoidosis must be taken into account when presented with unexplained ophthalmoplegia. Neurosarcoidosis has imaging properties very similar to other diseases such as a meningioma, and misdiagnosis occurs easily. Spontaneous recovery of ophthalmoplegia can rarely occur in neurosarcoidosis.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc21"},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10726560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138814658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraocular twin cysticercosis. 眼内双囊尾蚴病。

GMS ophthalmology cases Pub Date : 2023-09-29 eCollection Date: 2023-01-01 DOI: 10.3205/oc000226

Rohini Grover, Abhishek Varshney, Supreet Juneja, Upma Awashti, Sonali R Singh

引用次数: 0

Toxic anterior segment syndrome following trabeculectomy with mitomycin C. 丝裂霉素C小梁切除术后的毒性前段综合征。

GMS ophthalmology cases Pub Date : 2023-09-29 eCollection Date: 2023-01-01 DOI: 10.3205/oc000225

Helen Ginger-Eke, Chimdia Ogbonnaya, Annamalai Odayappan, Jude Shiweobi

{"title":"Toxic anterior segment syndrome following trabeculectomy with mitomycin C.","authors":"Helen Ginger-Eke, Chimdia Ogbonnaya, Annamalai Odayappan, Jude Shiweobi","doi":"10.3205/oc000225","DOIUrl":"10.3205/oc000225","url":null,"abstract":"Objective: Toxic anterior segment (TASS) is a rare acute sterile anterior segment inflammation that typically develops within 12 to 24 hours after an anterior segment surgery. The purpose of this case report is to alert surgeons to the possibility of this complication following any anterior segment surgery, including trabeculectomy, and to highlight the possible etiologies and measures to prevent it.Patient and method: A 58-year-old male glaucoma patient was initially managed medically for primary open angle glaucoma with antiglaucoma medications. There was rapidly progressive glaucomatous optic nerve damage in his left eye within the following year, despite the use of antiglaucoma medications, hence the need for trabeculectomy.Result: The post-operative condition of the patient's eye was stormy with diffuse limbus-to-limbus corneal edema and profound Descemet's membrane folds, among other features of TASS, with associated deteriorating visual acuity.Conclusion: Although there is no documented report of TASS following trabeculectomy with mitomycin C, surgeons should be alerted to this possibility. Preventive measures include extreme care to avoid errors while preparing and administering diluted solutions, especially medications that are administered into the intracameral space.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc17"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular tuberculosis masquerading as atypical ocular toxoplasmosis. 伪装为非典型眼弓形虫病的眼结核。

GMS ophthalmology cases Pub Date : 2023-09-29 eCollection Date: 2023-01-01 DOI: 10.3205/oc000227

Albert John Bromeo, Sweet Jorlene Lerit, Cheryl Arcinue

引用次数: 0

Dolichoectatic arterial compression of the chiasm and optic nerve: a case report. 视交叉和视神经的多点静态动脉压迫：一例报告。

GMS ophthalmology cases Pub Date : 2023-09-19 eCollection Date: 2023-01-01 DOI: 10.3205/oc000223

Sara Ceuppens, Ine Lambert, Marcel Ten Tusscher

引用次数: 0

Recurrence of gigantic overhanging bleb post excision: a case report. 巨大悬泡切除后复发1例报告。

GMS ophthalmology cases Pub Date : 2023-09-19 eCollection Date: 2023-01-01 DOI: 10.3205/oc000224

Kirti Singh, Mainak Bhattacharyya, Ravinder Saran, Nikhil Gotmare, Himshikha Aggarwal, Pragya Jain

{"title":"Recurrence of gigantic overhanging bleb post excision: a case report.","authors":"Kirti Singh, Mainak Bhattacharyya, Ravinder Saran, Nikhil Gotmare, Himshikha Aggarwal, Pragya Jain","doi":"10.3205/oc000224","DOIUrl":"10.3205/oc000224","url":null,"abstract":"Purpose: To report the case of an extremely large overhanging bleb, extending from superior fornix to limbus, in a 57-year-old poorly controlled diabetic, six years after trabeculectomy for an uncontrolled primary open angle glaucoma (POAG) with recurrence, months after complete excision.Methods: An overhanging bleb is defined as a filtering cicatrix which has been massaged downward over the cornea by eyelid action. It has been linked to anti-metabolite use during glaucoma filtering surgery. Despite being functional, these blebs result in patient discomfort ranging from foreign body sensation and lacrimation to dysphotopsia. A 57-year-old male presented with complaints of reduced vision, foreign body sensation, watering, and difficulty in eye closure in the left eye (OS) for past 6 months. He had undergone trabeculectomy with mitomycin C 6 years ago for advanced primary open-angle glaucoma with no follow-up beyond the initial one 4 weeks post-surgery.Results: At presentation, he had a giant multi-loculated, cystic filtering bleb (15 mm x 8 mm x 4-5 mm), which was carefully excised. Amniotic membrane was used as an anti-fibrotic as well to cover the defect. Seven months after surgery, there was recurrence of this overhanging cystic bleb when it was again excised with debulking of the conjunctiva done and cryotherapy applied to its margins.Conclusion: Although multiloculated cystic overhanging blebs have been documented before, such a large (posterior extent till fornix), thick-walled multiloculated bleb with histopathological evidence of chronic inflammatory process has not been reported prior.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc16"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0