Focal reactive nodular gliosis: an extremely rare retinal astrocytic tumor.

GMS ophthalmology cases Pub Date : 2023-12-12 eCollection Date: 2023-01-01 DOI:10.3205/oc000230
Saúl Villoria-Díaz, María Antonia Saornil-Álvarez, Ciro García-Álvarez, Elena García-Lagarto, Irene Bermúdez-Castellanos
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Abstract

Focal reactive nodular gliosis (FRNG) is an extremely rare benign retinal reactive astrocytic tumor that results from the proliferation of well-differentiated glial cells secondary to a variety of retinal conditions. We describe a case of this tumor in a 64-year-old male in association with a chorioretinal scar he has had since childhood. The symptom was sudden painful vision loss. In the clinical examination, iris rubeosis, posterior synechiae, cataract, vitreous haze and a suspected fundus mass were showed. B-scan ultrasonography demonstrated a retinal mass consistent with choroidal melanoma. The magnetic resonance imaging (MRI) showed a well-circumscribed mass with T1 hyperintensity and T2 hypointensity. Enucleation was performed and histopathologic and immunohistochemical studies confirmed the diagnosis of FRNG.

局灶性反应性结节性胶质瘤:一种极其罕见的视网膜星形胶质瘤。
局灶性反应性结节性胶质瘤(FRNG)是一种极其罕见的良性视网膜反应性星形胶质细胞瘤,是继发于多种视网膜疾病的分化良好的胶质细胞增殖所致。我们描述了一例这种肿瘤的病例,患者是一名 64 岁的男性,从小就患有脉络膜视网膜疤痕。患者的症状是突然出现疼痛性视力下降。在临床检查中,发现了虹膜红肿、后裂孔、白内障、玻璃体混浊和疑似眼底肿块。B 超扫描显示视网膜肿块与脉络膜黑色素瘤一致。磁共振成像(MRI)显示肿块呈环状,T1高密度,T2低密度。患者接受了去核手术,组织病理学和免疫组化检查证实了 FRNG 的诊断。
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