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Central serous chorioretinopathy following oral quetiapine. 口服喹硫平后中枢性浆液性脉络膜视网膜病变。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000221
Ceren Durmaz Engin, Mehmet Orcun Akdemir
{"title":"Central serous chorioretinopathy following oral quetiapine.","authors":"Ceren Durmaz Engin,&nbsp;Mehmet Orcun Akdemir","doi":"10.3205/oc000221","DOIUrl":"https://doi.org/10.3205/oc000221","url":null,"abstract":"<p><p>Central serous chorioretinopathy (CSCR) is a chorioretinal disease that is characterized by central vision loss and is usually seen in middle-aged males. It has been associated with the use of various drugs, including corticosteroids and phosphodiesterase inhibitors. We present the case of a 36-year-old male who developed CSCR after a few weeks of irregular use of quetiapine for his sleep problems. The clinical findings of the patient improved shortly after he stopped using the drug, and at the end of the two-month period complete recovery was observed. Quetiapine is an atypical antipsychotic that exerts its effects on dopamine and serotonin receptors. There are studies showing that these neurotransmitters may play a role in the control of choroidal vascular permeability, which is the underlying cause of CSCR. Therefore, we believe that quetiapine may have a causal relationship with CSCR. To our knowledge, this is the first case report documenting full recovery from quetiapine associated CSCR.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc13"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10000998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal imaging in a case of bilateral astrocytic hamartoma with retinitis pigmentosa. 双侧星形细胞错构瘤合并色素性视网膜炎的多模态影像分析。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000209
Sugandha Goel, Debmalya Das, Kumar Saurabh, Rupak Roy
{"title":"Multimodal imaging in a case of bilateral astrocytic hamartoma with retinitis pigmentosa.","authors":"Sugandha Goel,&nbsp;Debmalya Das,&nbsp;Kumar Saurabh,&nbsp;Rupak Roy","doi":"10.3205/oc000209","DOIUrl":"https://doi.org/10.3205/oc000209","url":null,"abstract":"<p><p>Astrocytic hamartoma is a benign glial tumor. It may be associated with tuberous sclerosis and can also be found incidentally on retinal examination as an isolated presentation. Here, we describe multimodal imaging characteristics of astrocytic hamartoma in a patient with retinitis pigmentosa. Spectral domain optical coherence tomography of both eyes showed moth-eaten optically empty spaces and hyperreflective dots along with foveal thinning. Multicolor image highlighted mulberry appearance of the lesion with green shift signifying elevated lesion. In infrared reflectance, lesion was hyporeflective with its margins well delineated. Green reflectance and blue reflectance highlighted calcification as multiple hyperreflective dots. Autofluorescence showed typical hyperautofluorescence.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc01"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10838263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgically induced scleral necrosis associated with concomitant tuberculosis infection: a diagnostic challenge. 手术诱发的巩膜坏死伴发结核感染:一个诊断挑战。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000212
Raul E Ruiz-Lozano, Alejandro Rodriguez-Garcia, Maria F Colorado-Zavala, Carlos Alvarez-Guzman
{"title":"Surgically induced scleral necrosis associated with concomitant tuberculosis infection: a diagnostic challenge.","authors":"Raul E Ruiz-Lozano,&nbsp;Alejandro Rodriguez-Garcia,&nbsp;Maria F Colorado-Zavala,&nbsp;Carlos Alvarez-Guzman","doi":"10.3205/oc000212","DOIUrl":"https://doi.org/10.3205/oc000212","url":null,"abstract":"<p><strong>Objective: </strong>Surgically induced scleral necrosis (SISN) is a potentially blinding sequela that may occur after any ocular procedure. SISN in the context of active tuberculosis is seldom seen. We report a case of a patient with asymptomatic tuberculosis who developed SISN after pterygium surgery.</p><p><strong>Methods: </strong>A 76-year-old Mexican-mestizo woman from Veracruz, Mexico, was referred to our clinic because of severe disabling pain and scleral thinning in her right eye.</p><p><strong>Results: </strong>Tubercular-related SISN was finally diagnosed and managed successfully with antitubercular therapy, topical and systemic corticosteroids.</p><p><strong>Conclusion: </strong>Tuberculosis must be considered as a differential diagnosis of high-risk patients in the context of refractory SISN in endemic countries.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc04"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10838261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinal artery occlusion following CoronaVac injection in a 45-year-old Filipino. 一名45岁菲律宾人注射CoronaVac后视网膜动脉闭塞。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000220
Daniel Jose M Mendoza, David Francis F Chan, Ellen N Yu-Keh, Bryan Christopher W Sy
{"title":"Retinal artery occlusion following CoronaVac injection in a 45-year-old Filipino.","authors":"Daniel Jose M Mendoza,&nbsp;David Francis F Chan,&nbsp;Ellen N Yu-Keh,&nbsp;Bryan Christopher W Sy","doi":"10.3205/oc000220","DOIUrl":"https://doi.org/10.3205/oc000220","url":null,"abstract":"<p><strong>Background: </strong>While complex public health challenges and the emergence of variants have impeded responses to the COVID pandemic, vaccines continue to represent a crucial tool in mitigating the risk of morbidity and mortality. Safety issues weigh heavily upon both the utility and acceptability of every vaccine. Reports of sight-threatening events are scarce.</p><p><strong>Case description: </strong>We report the case of a hypertensive 45-year-old Filipino who noted unilateral (right eye) blurring of vision within 48 hours of his first dose of CoronaVac (Sinovac, China), an inactivated SARS-CoV-2/COVID-19 vaccine, with macular retinal arterial occlusion noted on day 21 post-inoculation. Further work-up revealed abnormal glycemic, metabolic, inflammatory, and bleeding parameters. Vision improved from counting fingers to 20/100 at week 6 with no interventions.</p><p><strong>Conclusion: </strong>A potential association between retinal vasoocclusion and inoculation with CoronaVac in our patient is supported by the temporal sequence of events, multiple mechanisms put forward in other cases, and reports of vascular adverse reactions in large country-level trials. It is mitigated by the profound infrequency of such events and the potentially substantial risk for ocular ischemic events imparted by the patient's baseline clinical background. Continued understanding of vaccine adverse reactions, however rare, is important not only for individual patient safety. This is helpful in ensuring the utility of current vaccines and in preserving the acceptability of vaccines through and beyond the current pandemic.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc12"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10000997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal ectasia, cerulean (blue dot) cataract with acute hydrops in a child with Down's syndrome and hypothyroidism - a rare presentation. 伴有唐氏综合症和甲状腺功能减退的儿童角膜扩张、青色(蓝点)白内障伴急性积液-罕见的表现。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000215
Bharat Gurnani, Kirandeep Kaur, Shivanand Narayana
{"title":"Corneal ectasia, cerulean (blue dot) cataract with acute hydrops in a child with Down's syndrome and hypothyroidism - a rare presentation.","authors":"Bharat Gurnani,&nbsp;Kirandeep Kaur,&nbsp;Shivanand Narayana","doi":"10.3205/oc000215","DOIUrl":"https://doi.org/10.3205/oc000215","url":null,"abstract":"<p><p>Down's syndrome or trisomy 21 is a genetic disorder caused by presence of all or a part of a third copy of chromosome 21. Keratoconus occurs in up to 15% of the adult population with Down's syndrome. There is a close consortium between trisomy 21 and keratoconus (a conical ectatic protrusion of the cornea), and children with Down's syndrome are also susceptible to developing thyroid disease, including hypothyroidism and thyrotoxicosis with exophthalmos. The authors describe a case report on acute corneal hydrops with congenital cerulean cataract in a patient with Down's syndrome with hypothyroidism having bilateral advanced keratoconus. As per the detailed literature review, this is the first case of Down's syndrome with hypothyroidism presenting with acute corneal hydrops.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc07"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9278947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tenon's patch graft to the rescue during COVID-19 pandemic. 在COVID-19大流行期间，Tenon的贴片移植用于救援。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000218
Suchitra Panigrahi, Bidisha Mahapatra, Swarnamayee Baskey
{"title":"Tenon's patch graft to the rescue during COVID-19 pandemic.","authors":"Suchitra Panigrahi,&nbsp;Bidisha Mahapatra,&nbsp;Swarnamayee Baskey","doi":"10.3205/oc000218","DOIUrl":"https://doi.org/10.3205/oc000218","url":null,"abstract":"<p><strong>Objective: </strong>To report a case of bilateral Mooren's ulcer with impending corneal perforation in the right eye and perforated peripheral corneal ulcer in the left eye which successfully underwent Tenon's patch graft (TPG) with multilayered amniotic membrane grafting (AMG) as globe salvaging procedure during COVID-19 pandemic.</p><p><strong>Methods: </strong>Conjunctival resection was done on both the eyes followed by autologous Tenon's grafting with overlay amniotic membrane grafting in the left eye with perforation and multilayered AMG with AMG overlay in the right eye with impending perforation. Post-operatively topical antibiotics and steroids were prescribed.</p><p><strong>Results: </strong>At one month follow-up, the Tenon's graft and multilayered AMG were well-integrated with the surrounding healthy cornea with a good anatomical and visual outcome.</p><p><strong>Conclusion: </strong>Autologous Tenon's patch graft is a simple and cost-effective alternative to preserve globe integrity and prevent complications in emergency cases when immediate access to cornea transplantation is practically challenging.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc10"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9273583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare cause of recurrent subconjunctival hemorrhage: ocular vicarious menstruation. 复发性结膜下出血的罕见原因:眼代月经。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000213
Ali Riza Cenk Celebi, Elif Ganime Aygun
{"title":"A rare cause of recurrent subconjunctival hemorrhage: ocular vicarious menstruation.","authors":"Ali Riza Cenk Celebi,&nbsp;Elif Ganime Aygun","doi":"10.3205/oc000213","DOIUrl":"https://doi.org/10.3205/oc000213","url":null,"abstract":"<p><strong>Purpose: </strong>Vicarious menstruation is cyclical bleeding in extra-uterine locations that occurs during menstruation or within 48 h of its onset. We aim to present a 43-year-old female with ocular vicarious menstruation, its treatment, and a review of other published cases of ocular vicarious menstruation.</p><p><strong>Case description: </strong>A 43-year-old Caucasian female presented with a 15-year history of recurrent monthly unilateral subconjunctival hemorrhage. The episodes were cyclical and coincided with the onset of menses, lasting for approximately 10 to 14 days. Slit-lamp examination of the right eye showed nasally located subconjunctival hemorrhage. Detailed laboratory findings, including parameters for various hematological disorders, were normal. A follow-up examination 2 weeks later showed that the subconjunctival hemorrhage in the right eye was completely resolved. The patient was prescribed the oral contraceptive levonorgestrel/ethinyl estradiol and marked improvement at the recurrences of subconjunctival hemorrhage was noted during subsequent menses.</p><p><strong>Conclusion: </strong>Ocular vicarious menstruation is among the rarest causes of recurrent subconjunctival hemorrhage. A therapeutic trial of oral contraceptive should be considered in patients that present with ocular vicarious menstruation.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc05"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10849461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unilateral macular neovascularization formation during the follow-up of a 15-year-old boy with Bietti crystalline dystrophy and the successful treatment outcome with a single intravitreal ranibizumab injection. 一名15岁男孩Bietti结晶性营养不良的随访期间单侧黄斑新生血管的形成和单次玻璃体内注射兰珠单抗的成功治疗结果。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000214
Mustafa Kayabaşi, Ferdane Ataş, Ali Osman Saatci
{"title":"Unilateral macular neovascularization formation during the follow-up of a 15-year-old boy with Bietti crystalline dystrophy and the successful treatment outcome with a single intravitreal ranibizumab injection.","authors":"Mustafa Kayabaşi,&nbsp;Ferdane Ataş,&nbsp;Ali Osman Saatci","doi":"10.3205/oc000214","DOIUrl":"https://doi.org/10.3205/oc000214","url":null,"abstract":"<p><strong>Objective: </strong>To report the successful outcome with a single intravitreal ranibizumab injection in a 15-year-old boy with Bietti crystalline dystrophy (BCD) who developed a unilateral macular neovascularization (MNV).</p><p><strong>Methods: </strong>A retrospective case report.</p><p><strong>Results: </strong>A 15-year-old Caucasian boy with Bietti crystalline dystrophy was diagnosed to have a unilateral MNV a year after the initial examination with the help of multimodal imaging and he was treated with a single intravitreal ranibizumab injection. Five months later, visual acuity improved and anatomically a dry-looking macula was noted.</p><p><strong>Conclusion: </strong>MNV is among the rare macular complications of BCD. The present case is the third reported pediatric case with MNV in association with BCD and the first pediatric BCD patient who received a vascular endothelial growth factor inhibitor (anti-VEGF) agent.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc06"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9278949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Unilateral K-F ring in Wilson's disease. Wilson病的单侧K-F环。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000216
Shruti P Hegde, Sakthivel Senthil Kumar
{"title":"Unilateral K-F ring in Wilson's disease.","authors":"Shruti P Hegde,&nbsp;Sakthivel Senthil Kumar","doi":"10.3205/oc000216","DOIUrl":"https://doi.org/10.3205/oc000216","url":null,"abstract":"<p><p>Wilson's disease, also called hepatolenticular degeneration, has varied clinical manifestations and poses diagnostic challenges. Kayser-Fleischer ring, when present, is considered pathognomic of Wilson's disease. Although its presence is most commonly seen with the neuro-psychiatric form of the disease, it can also be present in hepatic form and asymptomatic patients. We report a case of unilateral Kayser-Fleischer ring in the normal, functional eye of a patient which subsequently led to the diagnosis of Wilson's disease in the patient. This case also highlights the examination of the normal appearing eye in all the patients presenting with complaints in only one eye.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc08"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9273587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microscope integrated OCT (Mi-OCT) guided retrieval of intrastromal corneal foreign body. 显微集成OCT (Mi-OCT)引导下角膜基质内异物取出术。
GMS ophthalmology cases Pub Date : 2023-01-01 DOI: 10.3205/oc000217
Ashish Markan, Kiran Chandra, Ramandeep Singh, Mohit Dogra
{"title":"Microscope integrated OCT (Mi-OCT) guided retrieval of intrastromal corneal foreign body.","authors":"Ashish Markan,&nbsp;Kiran Chandra,&nbsp;Ramandeep Singh,&nbsp;Mohit Dogra","doi":"10.3205/oc000217","DOIUrl":"https://doi.org/10.3205/oc000217","url":null,"abstract":"<p><strong>Introduction: </strong>To describe the role of microscope integrated optical tomography (Mi-OCT) in removal of intrastromal corneal foreign body.</p><p><strong>Methodology: </strong>A young male presented with trauma to the right eye with sugarcane stick. Ocular examination revealed two sugarcane particles, approximately 3.5 mm in greatest dimension, embedded in the corneal stroma. For removal of foreign body, Mi-OCT was switched on and the area of interest was focused. Sugarcane particles appeared as hyperreflective structures embedded in the corneal stroma with everted edges of the overlying corneal epithelium and anterior stroma.</p><p><strong>Results: </strong>Both the sugarcane particles were removed successfully under real time images provided by Mi-OCT without causing any inadvertent damage to the corneal stroma.</p><p><strong>Conclusion: </strong>Mi-OCT can be used as an adjunct in emergency surgical procedures like removal of intrastromal corneal foreign bodies with accurate precision.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"13 ","pages":"Doc09"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9273590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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