GMS ophthalmology cases最新文献

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Successful management of recalcitrant fungal keratitis with topical caspofungin. 外用卡泊霉素成功治疗顽固性真菌性角膜炎。
GMS ophthalmology cases Pub Date : 2022-07-18 eCollection Date: 2022-01-01 DOI: 10.3205/oc000206
Siddhi Goel, Arpit Sharma, Rajesh Sinha
{"title":"Successful management of recalcitrant fungal keratitis with topical caspofungin.","authors":"Siddhi Goel,&nbsp;Arpit Sharma,&nbsp;Rajesh Sinha","doi":"10.3205/oc000206","DOIUrl":"https://doi.org/10.3205/oc000206","url":null,"abstract":"<p><strong>Objective: </strong>To report a case of recalcitrant fungal keratitis successfully managed with topical caspofungin acetate in North India.</p><p><strong>Methods: </strong>Case report and literature review.</p><p><strong>Results: </strong>An 18-year-old male patient presented with complaints of redness, watering, pain and diminution of vision in the right eye and was referred to our centre as a case of corneal ulcer. The patient was examined and found to have a near total epithelial defect, with corneal infiltrates approximately 8x8 mm. A provisional diagnosis of polymicrobial keratitis was made based on corneal scraping suggestive of <i>S</i> <i>tap</i> <i>h</i> <i>ylococcus aureus</i> and confocal scan revealing fungal hyphae. The patient failed to respond to topical voriconazole 1%, natamycin 5% and moxifloxacin hydrochloride 0.5% with oral voriconazole. In view of the poor response to these drugs, the patient was subsequently administered topical caspofungin 0.5% in place of natamycin and continued on topical and oral voriconazole, in addition to topical moxifloxacin and cycloplegics, which finally led to healing with minimal scarring. The patient attained a best corrected visual acuity (BCVA) of 6/12.</p><p><strong>Conclusion: </strong>Topical caspofungin may be used as a useful and effective alternative in cases of recalcitrant fungal keratitis. It may result in healing with minimal scarring.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":"Doc19"},"PeriodicalIF":0.0,"publicationDate":"2022-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40438174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined central retinal artery and vein occlusion following trabeculectomy. 小梁切除术后视网膜中央动静脉联合闭塞。
GMS ophthalmology cases Pub Date : 2022-06-28 eCollection Date: 2022-01-01 DOI: 10.3205/oc000205
Albert John Bromeo, Sweet Jorlene Lerit, Patricia Grulla-Quilendrino, George Michael Sosuan, Edgar Leuenberger
{"title":"Combined central retinal artery and vein occlusion following trabeculectomy.","authors":"Albert John Bromeo,&nbsp;Sweet Jorlene Lerit,&nbsp;Patricia Grulla-Quilendrino,&nbsp;George Michael Sosuan,&nbsp;Edgar Leuenberger","doi":"10.3205/oc000205","DOIUrl":"https://doi.org/10.3205/oc000205","url":null,"abstract":"<p><p>Retinal vascular events may occur as rare complications of glaucoma procedures due to various factors, including exacerbation of ischemia in patients with pre-existing vascular comorbidities, toxic effect of mitomycin-C, and decompression retinopathy. We present the case of a 47-year-old hypertensive male who underwent trabeculectomy for advanced glaucoma in his right eye. At 3 weeks postoperatively, he presented with a drop in visual acuity to light perception with a spike in intraocular pressure. On examination, there was increased bleb vascularity as well as rubeosis. Fundoscopy revealed findings consistent with both central retinal artery occlusion and central retinal vein occlusion. Combined central retinal artery and vein occlusion is a rare retinal vascular condition. Neovascular glaucoma can occur as a sequelae of the ischemic process in the retina. Despite treatment, there is a poor visual prognosis, with the affected eye usually becoming blind from optic atrophy and neovascularization.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":"Doc18"},"PeriodicalIF":0.0,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40574969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Unusual extraconal orbital location of a cavernous hemangioma. 海绵状血管瘤的异常眶外位置。
GMS ophthalmology cases Pub Date : 2022-06-10 eCollection Date: 2022-01-01 DOI: 10.3205/oc000204
Gabriela Pacheco Callirgos, Francisco Javier Valentín Bravo, Pablo Panadero Meseguer, Víctor Manuel Asensio Sánchez
{"title":"Unusual extraconal orbital location of a cavernous hemangioma.","authors":"Gabriela Pacheco Callirgos,&nbsp;Francisco Javier Valentín Bravo,&nbsp;Pablo Panadero Meseguer,&nbsp;Víctor Manuel Asensio Sánchez","doi":"10.3205/oc000204","DOIUrl":"https://doi.org/10.3205/oc000204","url":null,"abstract":"<p><p>Cavernous hemangioma is the most common benign orbital and vascular tumor in adults. It is mostly located intraconally. Nevertheless, when the location is extraconal, the displacement of the globe is opposite the tumor's position. We describe an unusual presentation of this tumor in a 75-year-old female. The only symptom was the presence of epiphora. In the clinical examination, a mass was palpated on the lower orbital rim of the right eye. The magnetic resonance imaging (MRI) showed a well-circumscribed ovoid mass with a strong T2 hyperintensity and progressive contrast filling in T1. Excisional biopsy was performed, which confirmed the diagnosis of cavernous hemangioma. At five months of follow-up, there was no evidence of new symptoms.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":"Doc17"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40572438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute zonal occult outer retinopathy: optical coherence tomography angiography findings and treatment response. 急性带状隐匿性外视网膜病变:光学相干断层血管造影的发现和治疗反应。
GMS ophthalmology cases Pub Date : 2022-06-09 eCollection Date: 2022-01-01 DOI: 10.3205/oc000203
Erhan Özyol, Pelin Özyol
{"title":"Acute zonal occult outer retinopathy: optical coherence tomography angiography findings and treatment response.","authors":"Erhan Özyol,&nbsp;Pelin Özyol","doi":"10.3205/oc000203","DOIUrl":"https://doi.org/10.3205/oc000203","url":null,"abstract":"<p><p>Acute zonal occult outer retinopathy (AZOOR) is a rare condition primarily affecting the outer retina based on electrophysiologic studies. In addition to characteristic fundus appearance, spectral domain optical coherence tomography and fundus autofluorescence are unique in diagnosing AZOOR. There are a few reports on optical coherence tomography anjiography (OCTA) in AZOOR disease. In this report, we present a case using multimodal imaging including OCTA and treatment response to combined systemic antiviral, antiinflammatory, and immunosuppressive drugs. En-face OCTA outer retinal slab may provide useful tips for diagnosis and treatment response.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":"Doc16"},"PeriodicalIF":0.0,"publicationDate":"2022-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40572443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Toxoplasmosis chorioretinitis mimicking cytomegalovirus retinitis in an immunocompromised pediatric patient following bone marrow transplantation. 骨髓移植后免疫功能低下儿童患者的弓形虫病绒毛膜视网膜炎模拟巨细胞病毒视网膜炎。
GMS ophthalmology cases Pub Date : 2022-06-07 eCollection Date: 2022-01-01 DOI: 10.3205/oc000201
Anubhav Garg, Bryon R McKay, Carolina L M Francisconi, Rajeev H Muni
{"title":"Toxoplasmosis chorioretinitis mimicking cytomegalovirus retinitis in an immunocompromised pediatric patient following bone marrow transplantation.","authors":"Anubhav Garg,&nbsp;Bryon R McKay,&nbsp;Carolina L M Francisconi,&nbsp;Rajeev H Muni","doi":"10.3205/oc000201","DOIUrl":"https://doi.org/10.3205/oc000201","url":null,"abstract":"<p><strong>Objective: </strong>To review a case of toxoplasmosis chorioretinitis mimicking cytomegalovirus retinitis in an immunocompromised patient following bone marrow transplantation.</p><p><strong>Methods: </strong>Retrospective chart review of a 14-year-old female who had a history of leukemia and allogeneic bone marrow transplants prior to her ocular symptoms.</p><p><strong>Results: </strong>Anterior chamber fluid analysis was positive for <i>Toxoplasma gondii</i>. The patient responded well when cytomegalovirus retinitis treatment was switched to intravitreal clindamycin with systemic sulfadiazine and prednisone.</p><p><strong>Conclusions: </strong>This case demonstrates the challenges of diagnosing and treating retinal infections in immunocompromised patients as they may present with atypical findings that mimic other pathologies and may have contraindications against standard treatment.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":"Doc14"},"PeriodicalIF":0.0,"publicationDate":"2022-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40572439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Acute myeloid leukemia presenting as unilateral central retinal vein occlusion. 急性髓性白血病表现为单侧视网膜中央静脉阻塞。
GMS ophthalmology cases Pub Date : 2022-06-07 eCollection Date: 2022-01-01 DOI: 10.3205/oc000202
Ashok Kumar, Sandeep Shankar, Divya Kochhar, Amit Arora, Kapil Kumar
{"title":"Acute myeloid leukemia presenting as unilateral central retinal vein occlusion.","authors":"Ashok Kumar,&nbsp;Sandeep Shankar,&nbsp;Divya Kochhar,&nbsp;Amit Arora,&nbsp;Kapil Kumar","doi":"10.3205/oc000202","DOIUrl":"https://doi.org/10.3205/oc000202","url":null,"abstract":"<p><p>Ocular manifestations of leukemia are often bilateral and involve all ocular structures with non-specific features like retinal hemorrhages, cotton wool spots and choroidal infiltrates. We report a rare, atypical initial presentation of acute myeloid leukemia with unilateral central retinal vein occlusion in a middle-aged male. This case will raise awareness among ophthalmologists to recognize and diagnose underlying systemic disease early and decrease systemic morbidity in consultation with a hematologist.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":"Doc15"},"PeriodicalIF":0.0,"publicationDate":"2022-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40572441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Choroidal metastasis as a presenting feature in a metastatic lung carcinoma. 脉络膜转移是转移性肺癌的主要表现。
GMS ophthalmology cases Pub Date : 2022-05-20 eCollection Date: 2022-01-01 DOI: 10.3205/oc000200
Mukesh Jain, Deepika C Parameswarappa
{"title":"Choroidal metastasis as a presenting feature in a metastatic lung carcinoma.","authors":"Mukesh Jain,&nbsp;Deepika C Parameswarappa","doi":"10.3205/oc000200","DOIUrl":"https://doi.org/10.3205/oc000200","url":null,"abstract":"<p><p>We report a case of a 65-year-old female who presented to us with diminution of vision in the right eye. She was only able to perceive light in the right eye, and the left eye had a vision of 20/20, N6. Anterior segment examination in both eyes was unremarkable except for senile cataract in the left eye. Posterior segment examination revealed features of choroidal metastasis in both eyes and exudative retinal detachment in the right eye. Multimodal imaging helped in the further confirmation of metastatic lesions. Right-eye fundus autofluorescence showed hyperautofluorescent lesions, ultrasound B-scan showed an elevated mass lesion in the choroid with moderate to high internal echogenicity, and optical coherence tomography showed a lumpy-bumpy appearance of the retinal pigment epithelium as well as an elevated choroidal mass lesion beneath it. On detailed systemic evaluation, the primary site of cancer was found to be the lungs. The patient was referred to a pulmonologist and an oncologist for chemotherapy and further management.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":"Doc13"},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40572442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous bilateral inflammatory choroidal neovascularization in a case of healed serpiginous-like choroiditis. 同时双侧炎性脉络膜新生血管愈合一例蛇形样脉络膜炎。
GMS ophthalmology cases Pub Date : 2022-05-20 eCollection Date: 2022-01-01 DOI: 10.3205/oc000199
Gitanjli Sood, Ramanuj Samanta, Devesh Kumawat, Prateek Nishant
{"title":"Simultaneous bilateral inflammatory choroidal neovascularization in a case of healed serpiginous-like choroiditis.","authors":"Gitanjli Sood,&nbsp;Ramanuj Samanta,&nbsp;Devesh Kumawat,&nbsp;Prateek Nishant","doi":"10.3205/oc000199","DOIUrl":"https://doi.org/10.3205/oc000199","url":null,"abstract":"<p><strong>Objective: </strong>Inflammatory choroidal neovascularization (i-CNV) is an infrequent but sight-threatening complication of posterior uveitis. Although it can occur in a wide range of infectious and non-infectious uveitides, presence of simultaneous bilateral i-CNV is rare. In this report, we present a unique case of bilateral simultaneous i-CNV in a young patient of healed tubercular serpiginous-like choroiditis.</p><p><strong>Method: </strong>A 20-year-old male presented with recent worsening of vision in the right eye for one month. Fundus examination revealed bilateral multifocal healed choroiditis lesions with right eye tiny subfoveal hemorrhage raising the suspicion of an underlying choroidal neovascularization. Fundus fluorescein angiography and optical coherence tomography confirmed presence of choroidal neovascular membrane in both eyes.</p><p><strong>Result: </strong>Resolution of activity was noted in both eyes after bilateral sequential intravitreal bevacizumab injections.</p><p><strong>Conclusion: </strong>Inflammatory choroidal neovascularization may be seen in patients with healed tubercular serpiginous-like choroiditis, after a long period of quiescence. Simultaneous bilateral presentation is rare but possible, requiring mandatory multimodal imaging of both eyes under high index of suspicion. Early institution of anti-vascular endothelial growth factor may salvage optimum vision in such a scenario.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":"Doc12"},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40571987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal imaging of a sporadic retinal astrocytic hamartoma simulating retinoblastoma in a newborn. 新生儿散发性视网膜星形细胞错构瘤模拟视网膜母细胞瘤的多模态成像。
GMS ophthalmology cases Pub Date : 2022-05-20 eCollection Date: 2022-01-01 DOI: 10.3205/oc000198
Bilge Batu Oto, Aslihan Yilmaz Çebi, Oguzhan Kiliçarslan, Ahmet Murat Sarici
{"title":"Multimodal imaging of a sporadic retinal astrocytic hamartoma simulating retinoblastoma in a newborn.","authors":"Bilge Batu Oto,&nbsp;Aslihan Yilmaz Çebi,&nbsp;Oguzhan Kiliçarslan,&nbsp;Ahmet Murat Sarici","doi":"10.3205/oc000198","DOIUrl":"https://doi.org/10.3205/oc000198","url":null,"abstract":"<p><strong>Introduction: </strong>To report a sporadic astrocytic hamartoma simulating retinoblastoma in a newborn.</p><p><strong>Methods: </strong>Clinical data was reviewed retrospectively.</p><p><strong>Results: </strong>A 3-month-old baby with a history of perinatal asphyxia was referred to our ocular oncology clinic with suspected retinoblastoma in the left eye. Dilated fundoscopy revealed a solitary tumor covering the optic disc at the left eye. The whitish-yellow lesion was well-defined, opaque, and minimally calcified. High internal reflectivity and posterior shadowing due to the intralesional calcification, and intratumoral cystic spaces were observed in B-scan ultrasound imaging. Optical coherence tomography imaging showed an intraretinal tumor with cystic spaces and posterior shadowing. The tumor was diagnosed as an astrocytic hamartoma. The systemic evaluation was negative for phacomatoses. The lesion has been observed with multimodal imaging for six years without significant changes.</p><p><strong>Conclusions: </strong>Retinal astrocytic hamartomas are benign tumors that arise within the retinal nerve fiber layer. Differential diagnosis constitutes high importance since they may be misdiagnosed as retinoblastoma, and therefore may be overtreated. Whereas retinoblastoma requires immediate treatment, retinal astrocytic hamartomas are commonly followed-up. Multimodal imaging with B-scan ultrasonography and optical coherence tomography are useful in distinguishing those two entities.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":"Doc11"},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40572440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative optical coherence tomography (I-OCT) assisted passage of the encircling element during retinal detachment surgery 术中光学相干断层扫描(I-OCT)辅助视网膜脱离手术中环形元件的通过
GMS ophthalmology cases Pub Date : 2022-04-01 DOI: 10.3205/oc000197
A. Markan, N. Gupta, Basavaraj Tigari, Ramandeep Singh, M. Dogra
{"title":"Intraoperative optical coherence tomography (I-OCT) assisted passage of the encircling element during retinal detachment surgery","authors":"A. Markan, N. Gupta, Basavaraj Tigari, Ramandeep Singh, M. Dogra","doi":"10.3205/oc000197","DOIUrl":"https://doi.org/10.3205/oc000197","url":null,"abstract":"Objective: To describe the role of microscope integrated optical tomography (Mi-OCT) in passage of the encircling element during retinal detachment surgery. Materials and methods: Mi-OCT was switched on while passing scleral anchoring sutures to secure the encircling element. The depth of the suture tract was seen in real time while the needle was passed through the sclera. The amount of scleral intend achieved was assessed using Mi-OCT at the end of the surgery. Results: The depth of needle tract through the sclera and the amount of scleral indentation achieved while tying the sutures could be successfully analyzed using Mi-OCT. Conclusion: Mi-OCT can be used as an adjunct while training vitreoretinal fellows and trainees in surgical procedures like passage of scleral sutures for anchoring the encircling element.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42263874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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