Unilateral macular neovascularization formation during the follow-up of a 15-year-old boy with Bietti crystalline dystrophy and the successful treatment outcome with a single intravitreal ranibizumab injection.

Mustafa Kayabaşi, Ferdane Ataş, Ali Osman Saatci
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引用次数: 1

Abstract

Objective: To report the successful outcome with a single intravitreal ranibizumab injection in a 15-year-old boy with Bietti crystalline dystrophy (BCD) who developed a unilateral macular neovascularization (MNV).

Methods: A retrospective case report.

Results: A 15-year-old Caucasian boy with Bietti crystalline dystrophy was diagnosed to have a unilateral MNV a year after the initial examination with the help of multimodal imaging and he was treated with a single intravitreal ranibizumab injection. Five months later, visual acuity improved and anatomically a dry-looking macula was noted.

Conclusion: MNV is among the rare macular complications of BCD. The present case is the third reported pediatric case with MNV in association with BCD and the first pediatric BCD patient who received a vascular endothelial growth factor inhibitor (anti-VEGF) agent.

一名15岁男孩Bietti结晶性营养不良的随访期间单侧黄斑新生血管的形成和单次玻璃体内注射兰珠单抗的成功治疗结果。
目的:报告单次玻璃体内注射雷尼单抗治疗15岁男孩Bietti结晶性营养不良(BCD)并发单侧黄斑新生血管(MNV)的成功结果。方法:回顾性病例报告。结果:一名患有Bietti晶体营养不良症的15岁高加索男孩在多模态成像的帮助下进行初步检查一年后被诊断为单侧MNV,并接受单次玻璃体内注射雷尼单抗治疗。5个月后,视力改善,解剖上发现干性黄斑。结论:MNV是BCD罕见的黄斑并发症之一。本病例是第三例报道的小儿MNV合并BCD病例,也是第一例接受血管内皮生长因子抑制剂(抗vegf)治疗的小儿BCD患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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