Electromagnetic Biology and Medicine最新文献

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The protective role of 5-hydroxy-1,4-naphthoquinone against the harmful effects of 50 Hz electric field in rat lung tissue. 5-羟基-1,4-萘醌对50Hz电场对大鼠肺组织损伤的保护作用。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-10-02 Epub Date: 2023-12-29 DOI: 10.1080/15368378.2023.2265935
Nurgül Şenol, Melda Şahin, Uğur Şahin
{"title":"The protective role of 5-hydroxy-1,4-naphthoquinone against the harmful effects of 50 Hz electric field in rat lung tissue.","authors":"Nurgül Şenol, Melda Şahin, Uğur Şahin","doi":"10.1080/15368378.2023.2265935","DOIUrl":"10.1080/15368378.2023.2265935","url":null,"abstract":"<p><p>There is strong scientific evidence that the electric field is harmful to life. Exposure to an electric field (EF) can cause lung toxicity and respiratory disorders. In addition, the electric field has been shown to cause tissue damage through inflammation and apoptosis. Juglone (JUG) is one of the powerful antioxidants with anti-apoptotic and anti-inflammatory, various pharmacological properties in the biological system. In this study, we evaluated the efficacy of JUG against the potential adverse effects of electric field on the lung. Twenty-four Wistar albino rats were randomly divided into three groups; control group (Cont), EF group, and EF exposure+JUG-treated group (EJUG). After routine histological procedures, sections stained with hematoxylin-eosin (H&E) showed significant changes in lung tissues in the EF group compared to the Cont group. Significant protective effects were observed in the building volumes and histopathology in the EJUG group. Our immunohistochemical and gene expression results increased the expression of caspase-3 and tumor necrosis factor alpha (TNF-α) in the EF group (<i>p</i> < 0.05). Juglon increased cytokine signal suppressor (SOCS) expression (<i>p</i> < 0.001). These findings were consistent with the antioxidant effect of JUG treatment. We reasoned that exposure to EF damaged rat lung tissues and administration of JUG alleviated the complications caused by 50 Hz EF.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"133-143"},"PeriodicalIF":1.7,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41174750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Four minutes of capacitive and resistive electric transfer therapy increased jump performance. 四分钟的容性和电阻性电转移治疗提高了跳跃性能。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-10-02 Epub Date: 2023-12-29 DOI: 10.1080/15368378.2023.2290742
Michio Wachi, Takumi Jiroumaru, Ayako Satonaka, Masae Ikeya, Nobuko Shichiri, Junko Ochi, Yutaro Hyodo, Takamitsu Fujikawa
{"title":"Four minutes of capacitive and resistive electric transfer therapy increased jump performance.","authors":"Michio Wachi, Takumi Jiroumaru, Ayako Satonaka, Masae Ikeya, Nobuko Shichiri, Junko Ochi, Yutaro Hyodo, Takamitsu Fujikawa","doi":"10.1080/15368378.2023.2290742","DOIUrl":"10.1080/15368378.2023.2290742","url":null,"abstract":"<p><p>Capacitive and resistive electric transfer (CRET) therapy can improve flexibility and increase muscle activity and may be useful as a warm-up technique. This study examined the effects of short-time CRET on jump performance. Thirty healthy men (age range, 20-40 years) were randomly divided into passive (<i>n</i> = 15) and active (<i>n</i> = 15) warm-up groups. The participants and statisticians were blinded to the participant allocation. The passive warm-up group underwent 4 min of CRET therapy on their posterior lower legs. The active warm-up group performed stretching and jogging for 4 min. Calf muscle temperature and rebound jump (RJ) index were measured before and after the intervention. The mean (± standard deviation) muscle temperature increased by 2.0 ± 0.5°C and 1.4 ± 0.6°C in the passive and active warm-up groups, respectively (<i>p</i> < 0.05). RJ index increased significantly in both groups (<i>p</i> < 0.05). Therefore, passive warm-up using CRET may help avoid energy loss while increasing the muscle temperature in a short time when compared with traditional active warm-up techniques.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"144-149"},"PeriodicalIF":1.7,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138500000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing the antibacterial effect of iron oxide and silver nanoparticles by extremely low frequency electric fields (ELF-EF) against S. aureus. 通过极低频电场(ELF-EF)增强氧化铁和银纳米颗粒对金黄色葡萄球菌的抗菌作用。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-07-03 Epub Date: 2023-05-08 DOI: 10.1080/15368378.2023.2208610
Ebtesam A Mohamad, Marwa A Ramadan, Marwa M Mostafa, Mona S Elneklawi
{"title":"Enhancing the antibacterial effect of iron oxide and silver nanoparticles by extremely low frequency electric fields (ELF-EF) against <i>S. aureus</i>.","authors":"Ebtesam A Mohamad,&nbsp;Marwa A Ramadan,&nbsp;Marwa M Mostafa,&nbsp;Mona S Elneklawi","doi":"10.1080/15368378.2023.2208610","DOIUrl":"10.1080/15368378.2023.2208610","url":null,"abstract":"<p><p><i>Staphylococcus aureus</i> is the cause of many infectious and inflammatory diseases and a lot of studies aim to discover alternative ways for infection control and treatment rather than antibiotics. This work attempts to reduce bacterial activity and growth characteristics of <i>Staphylococcus aureus</i> using nanoparticles (iron oxide nanoparticles and silver nanoparticles) and extremely low frequency electric fields (ELF-EF). Bacterial suspensions of <i>Staphylococcus aureus</i> were used to prepare the samples, which were evenly divided into groups. Control group, 10 groups were exposed to ELF-EF in the frequency range (0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, and 1 Hz), iron oxide NPs treated group, iron oxide NPs exposed to 0.8 Hz treated group, silver NPs treated group and the last group was treated with silver NPs and 0.8 Hz. Antibiotic sensitivity testing, dielectric relaxation, and biofilm development for the living microbe were used to evaluate morphological and molecular alterations. Results showed that combination of nanoparticles with ELF-EF at 0.8 Hz enhanced the bacterial inhibition efficiency, which may be due to structural changes. These were supported by the dielectric measurement results which indicated the differences in the dielectric increment and electrical conductivity for the treated samples compared with control samples. This was also confirmed by biofilm formation measurements obtained. We may conclude that the exposure of <i>Staphylococcus aureus</i> bacteria to ELF-EF and NPs affected its cellular activity and structure. This technique is nondestructive, safe and fast and could be considered as a mean to reduce the use of antibiotics.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"99-113"},"PeriodicalIF":1.7,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9431757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Assessing the effect of selenium on cyclin D1 level and nuclear factor kappa b activity in NIH/3T3 fibroblast cells at 2100 MHz electromagnetic field exposure. 评估硒在2100MHz电磁场暴露下对NIH/3T3成纤维细胞中细胞周期蛋白D1水平和核因子κb活性的影响。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-07-03 Epub Date: 2023-08-28 DOI: 10.1080/15368378.2023.2252457
Dilek Duzgun Ergun, Nural Pastaci Ozsobaci, Tuba Yilmaz, Dervis Ozcelik, Mustafa Tunaya Kalkan
{"title":"Assessing the effect of selenium on cyclin D1 level and nuclear factor kappa b activity in NIH/3T3 fibroblast cells at 2100 MHz electromagnetic field exposure.","authors":"Dilek Duzgun Ergun, Nural Pastaci Ozsobaci, Tuba Yilmaz, Dervis Ozcelik, Mustafa Tunaya Kalkan","doi":"10.1080/15368378.2023.2252457","DOIUrl":"10.1080/15368378.2023.2252457","url":null,"abstract":"<p><p>Although there are numerous studies on the health impacts of electromagnetic field (EMF) of mobile phone operation frequency 2100 MHz, the published works present contradicting results. Long-term exposure to mobile phone frequencies has unclear health hazards. Therefore, it is important to investigate the molecular mechanism of possible biological effects in mobile phone exposure and to determine the corresponding biological markers. Towards this end, this study was designed to assess the effect of 200 nM selenium (Se) on cell viability% [trypan blue], cell cycle biomarker [cyclin D1] and the transcription factor [nuclear factor kappa b (NF-κB)] in NIH/3T3 fibroblast cells when exposed to 2100 MHz mobile phone frequency. When 2100 MHz EMF was exposed to NIH/3T3 fibroblast cells, the cell viability% was reduced, whereas cyclin D1 level and NF-kB activity increased. Also we show that Se supplementation decreases the effects of 2100 MHz EMF on these parameters. Although future studies will be required to investigate the biological effects of EMF emitted by mobile phones, the results obtained here provide an insight into the molecular mechanisms and specifically underlying selenium's protective effect against 2100 MHz EMF exposure.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"123-132"},"PeriodicalIF":1.7,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10466143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electromagnetic field exposure to human head model with various metal objects at sub-6 GHz frequencies. 在低于6GHz的频率下,暴露于具有各种金属物体的人类头部模型的电磁场。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-07-03 Epub Date: 2023-06-04 DOI: 10.1080/15368378.2023.2220736
Niyazi İl, Kayhan Ateş, Şükrü Özen
{"title":"Electromagnetic field exposure to human head model with various metal objects at sub-6 GHz frequencies.","authors":"Niyazi İl,&nbsp;Kayhan Ateş,&nbsp;Şükrü Özen","doi":"10.1080/15368378.2023.2220736","DOIUrl":"10.1080/15368378.2023.2220736","url":null,"abstract":"<p><p>In recent years, the interactions of metal objects in human body with electromagnetic fields caused by devices working at fifth-generation (5G) frequencies have been studied by various researchers. A motivation behind this research was to evaluate the human body absorption of electromagnetic energy operating at sub-6 GHz 5G applications. According to this, the specific absorption rate (SAR) caused by new generation mobile phones was investigated in human heads wearing metal-framed spectacles and having metallic implants or earrings to analyse electromagnetic field exposure. A realistic human head model, including some metal objects, was numerically calculated, and analysed in terms of non-ionizing dosimetry. Simulations were carried out with the finite integration technique (FIT) based commercial software in the frequencies of 0.9, 1.8, 2.1, 2.45, 3.5 and 5 GHz, respectively. The maximum SAR of 14 × 10<sup>-5</sup> W/kg for 10 g average tissue was calculated at 2.45 GHz frequency in the head model with earrings. The highest electric field strength of 0.52 V/m was observed at a 1.8 GHz frequency in the head model with all metal objects equipped. Results show that metal objects such as spectacles, dental implants and earrings can cause an increase in the SAR values for external biological tissues, and metal objects can behave as a kind of shield for deeper tissues. However, the obtained values are below the limits of international organisations.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"114-122"},"PeriodicalIF":1.7,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9574530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The increase in c-fos expression in epileptic seizures is inhibited by magnetic field application, but not KCa1.1 channel expression. 磁场作用可抑制癫痫发作时c-fos表达的增加,但不抑制KCa1.1通道的表达。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-04-03 DOI: 10.1080/15368378.2023.2247027
Mehmet Zülkif Akdağ, Emrah Oğraş, Züleyha Doğanyiğit, Enes Akyüz, Mahmut Berat Akdag, Aslı Okan, Veysi Akpolat, I Rem Küllü
{"title":"The increase in c-fos expression in epileptic seizures is inhibited by magnetic field application, but not K<sub>Ca</sub>1.1 channel expression.","authors":"Mehmet Zülkif Akdağ,&nbsp;Emrah Oğraş,&nbsp;Züleyha Doğanyiğit,&nbsp;Enes Akyüz,&nbsp;Mahmut Berat Akdag,&nbsp;Aslı Okan,&nbsp;Veysi Akpolat,&nbsp;I Rem Küllü","doi":"10.1080/15368378.2023.2247027","DOIUrl":"https://doi.org/10.1080/15368378.2023.2247027","url":null,"abstract":"<p><p>The aim of this study was to understand the expression of big potassium (BK, K<sub>Ca</sub>1.1) channels in epileptic seizures under magnetic field application. Forty Wistar albino adult male rats were divided into five groups (<i>n</i> = 8). First group rats were control group. Pentylenetetrazole (PTZ) administrated to second group rats to induce the seizures with 35 mg/kg intraperitoneally injection every two days. Levetiracetam (LEV) i.p. at a dose of 108 mg/kg was given to third group rats as positive control group (PC) before 20 minutes PTZ administration. Pulsed magnetic field with 1.5 mT was exposed to the fourth group rats for 3 hours a day for 1 month as magnetic field (MF) group. 1.5 mT pulsed magnetic field was exposed to the fifth group rats for 3 hours a day for 1 month in addition to PTZ administration (PTZ+MF). K<sub>Ca</sub>1.1 not changed in hippocampus of PTZ rats while increased in frontal cortex and pons for PTZ group but not changed with magnetic field exposure. K<sub>Ca</sub>1.1 increased in heart of PTZ animals and turned back to mean control values with magnetic field exposure. Suppressing the expected increase of c-fos protein expression in seizures with magnetic field application but not being able to change the K<sub>Ca</sub>1.1 expression shows that new studies can be done by increasing the frequency of 1.5 mT magnetic field.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":"42 2","pages":"81-97"},"PeriodicalIF":1.7,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10441498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue. 脉冲电磁场和n -乙酰半胱氨酸对玻璃化小鼠卵巢组织移植的影响。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-04-03 DOI: 10.1080/15368378.2023.2246503
Khadijeh Rasaeifar, Saeed Zavareh, Maryam Hajighasem-Kashani, Meysam Nasiri
{"title":"Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue.","authors":"Khadijeh Rasaeifar,&nbsp;Saeed Zavareh,&nbsp;Maryam Hajighasem-Kashani,&nbsp;Meysam Nasiri","doi":"10.1080/15368378.2023.2246503","DOIUrl":"https://doi.org/10.1080/15368378.2023.2246503","url":null,"abstract":"<p><p>In this experimental study, adult female NMRI mice were randomly assigned to five groups: control ;(fresh ovarian transplantation, OT); sham ;(vitrified OT); NAC ;(vitrified OT treated with N-acetyl cysteine, NAC); EMF ;(vitrified OT treated with pulsed electromagnetic fields, PEMF); and NAC+EMF ;(vitrified OT combined with NAC and PEMF). We conducted histological assessments to evaluate follicle reservation and vascularization. Furthermore, we examined the relative expression of <i>Fgf-2, Vegf, Tnf-α, Il-6, Il-1</i>, and <i>Cd31</i> genes on days 2 and 7 after OT. Additionally, we measured total antioxidant capacity (TAC), malondialdehyde (MDA) levels, as well as the activity of superoxide dismutase (SOD) and glutathione peroxidase (GPX). Our results demonstrated that NAC, PEMF, and NAC+PEMF treatments significantly increased the number of follicles. Moreover, we observed a more pronounced development of vascularization in the NAC, PEMF, and PEMF+NAC groups. The relative expression levels of <i>Fgf-2, Vegf, Tnf-α, Il-1β</i>, and <i>Il-6</i> were significantly elevated in the NAC, PEMF, and NAC+PEMF groups. Notably, TAC levels decreased significantly in the NAC group compared to the control group. Additionally, the MDA level showed a significant decrease in the PEMF+NAC group when compared to the other groups. Overall, the combination of NAC and PEMF exhibited a synergistic effect in promoting angiogenesis and protecting against oxidative stress and inflammation during OT.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":"42 2","pages":"67-80"},"PeriodicalIF":1.7,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10066169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive effects of pulsed electromagnetic fields on behavior, immune function, and oxidative and inflammatory state in old mice. 脉冲电磁场对老年小鼠行为、免疫功能、氧化和炎症状态的积极影响。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-04-03 DOI: 10.1080/15368378.2023.2243994
Estefanía Díaz-Del Cerro, Mónica De la Fuente
{"title":"Positive effects of pulsed electromagnetic fields on behavior, immune function, and oxidative and inflammatory state in old mice.","authors":"Estefanía Díaz-Del Cerro,&nbsp;Mónica De la Fuente","doi":"10.1080/15368378.2023.2243994","DOIUrl":"https://doi.org/10.1080/15368378.2023.2243994","url":null,"abstract":"<p><p>The establishment of chronic oxidative and inflammatory stress with aging leads to the deterioration of the nervous and immune systems and, consequently, to the loss of health. The aim of this work was to study the effect of exposure to low-frequency pulsed electromagnetic fields (PEMFs) produced by the NEURALTER® system (15 min/day for 4 weeks) in the behavior, immune functions, and oxidative and inflammatory state of old mice. Female old CD1 mice were divided into three groups: control group, handling control group and Neuralter group. Then, behavioral tests were performed, and peritoneal leukocytes were extracted to analyze function, oxidative and inflammatory parameters. In peritoneal leukocytes from old mice, the effects <i>in vitro</i> of 15 min with NEURALTER® were studied on function and oxidative parameters. The results show that after this type of treatment, old mice had greater coordination and locomotion, better immune function, and an oxidative-inflammatory state. Similarly, the immune function and oxidative state of leukocytes showed an improvement when these cells were exposed directly to the NEURALTER® system. In conclusion, the exposure to low-frequency PEMFs produced by the NEURALTER® system has beneficial effects on health in aging. In addition, this effect is direct, at least in part, on immune cells.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":"42 2","pages":"51-66"},"PeriodicalIF":1.7,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10068745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative proteomics reveals effects of environmental radiofrequency electromagnetic fields on embryonic neural stem cells. 定量蛋白质组学揭示了环境射频电磁场对胚胎神经干细胞的影响。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-04-03 DOI: 10.1080/15368378.2023.2243980
Guangzhou An, Yuntao Jing, Tao Zhao, Wei Zhang, Ling Guo, Juan Guo, Xia Miao, Junling Xing, Jing Li, Junye Liu, Guirong Ding
{"title":"Quantitative proteomics reveals effects of environmental radiofrequency electromagnetic fields on embryonic neural stem cells.","authors":"Guangzhou An,&nbsp;Yuntao Jing,&nbsp;Tao Zhao,&nbsp;Wei Zhang,&nbsp;Ling Guo,&nbsp;Juan Guo,&nbsp;Xia Miao,&nbsp;Junling Xing,&nbsp;Jing Li,&nbsp;Junye Liu,&nbsp;Guirong Ding","doi":"10.1080/15368378.2023.2243980","DOIUrl":"https://doi.org/10.1080/15368378.2023.2243980","url":null,"abstract":"<p><p>The effects of environmental radiofrequency electromagnetic fields (RF-EMF) on embryonic neural stem cells have not been determined, particularly at the proteomic level. This study aims to elucidate the effects of environmental levels of RF-EMF radiation on embryonic neural stem cells. Neuroectodermal stem cells (NE-4C cells) were randomly divided into a sham group and an RF group, which were sham-exposed and continuously exposed to a 1950 MHz RF-EMF at 2 W/kg for 48 h. After exposure, cell proliferation was determined by a Cell Counting Kit-8 (CCK8) assay, the cell cycle distribution and apoptosis were measured by flow cytometry, protein abundance was detected by liquid chromatography-tandem mass spectrometry (LC-MS/MS), and mRNA expression was evaluated by quantitative reverse transcription polymerase chain reaction (qRT-PCR). We did not detect differences in cell proliferation, cell cycle distribution, and apoptosis between the two groups. However, we detected differences in the abundance of 23 proteins between the two groups, and some of these differences were consistent with alterations in transcript levels determined by qRT-PCR (<i>P</i> < 0.05). A bioinformatics analysis indicated that the differentially regulated proteins were mainly enriched in 'localization' in the cellular process category; however, no significant pathway alterations in NE-4C cells were detected. We conclude that under the experimental conditions, low-level RF-EMF exposure was not neurotoxic but could induce minor changes in the abundance of some proteins involved in neurodevelopment or brain function.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":"42 2","pages":"41-50"},"PeriodicalIF":1.7,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10121127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adverse effects of 900, 1800 and 2100 MHz radiofrequency radiation emitted from mobile phones on bone and skeletal muscle. 移动电话发出的900、1800及2100兆赫射频辐射对骨骼及骨骼肌的不利影响。
IF 1.7 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2023-01-02 DOI: 10.1080/15368378.2023.2179065
Hava Bektas, Asrin Nalbant, Mahmut Berat Akdag, Canan Demir, Servet Kavak, Suleyman Dasdag
{"title":"Adverse effects of 900, 1800 and 2100 MHz radiofrequency radiation emitted from mobile phones on bone and skeletal muscle.","authors":"Hava Bektas,&nbsp;Asrin Nalbant,&nbsp;Mahmut Berat Akdag,&nbsp;Canan Demir,&nbsp;Servet Kavak,&nbsp;Suleyman Dasdag","doi":"10.1080/15368378.2023.2179065","DOIUrl":"https://doi.org/10.1080/15368378.2023.2179065","url":null,"abstract":"<p><p>The goal of this study was to biomechanically and morphologically research both the impact of mobile phone like radiofrequency radiations (RFR) on the tibia and the effects on skeletal muscle through oxidative stress parameters. Fifty-six rats (200-250 g) were put into groups: healthy sham (n = 7), healthy RFR (900, 1800, 2100 MHz) (n = 21), diabetic sham (n = 7) and diabetic RFR (900, 1800, 2100 MHz) (n = 21). Over a month, each group spent two hours/day in a Plexiglas carousel. The rats in the experimental group were exposed to RFR, but the sham groups were not. At the end of the experiment, the right tibia bones and skeletal muscle tissue were removed. The three-point bending test and radiological evaluations were performed on the bones, and CAT, GSH, MDA, and IMA in muscles were measured. There were differences in biomechanics properties and radiological evaluations between the groups (p < .05). In the measurements in the muscle tissues, significant differences were statistically found (p < .05). The average whole-body SAR values for GSM 900, 1800 and 2100 MHz were 0.026, 0.164, and 0.173 W/kg. RFRs emitted from mobile phone may cause adverse effects on tibia and skeletal muscle health, though further studies are needed.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":"42 1","pages":"12-20"},"PeriodicalIF":1.7,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9246387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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