Electromagnetic Biology and Medicine最新文献

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One-year follow-up of thyroid status in rats exposed to 2.45 Ghz radiofrequency radiation during the prenatal period. 产前暴露于2.45 Ghz射频辐射的大鼠甲状腺状态的一年随访。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-10-22 DOI: 10.1080/15368378.2025.2577318
Cemal Özyılmaz, Süleyman Daşdağ, Mehmet Faruk Oktay, Engin Ulukaya, Merve Erkısa Genel, Funda Emre, Korkut Yeğin
{"title":"One-year follow-up of thyroid status in rats exposed to 2.45 Ghz radiofrequency radiation during the prenatal period.","authors":"Cemal Özyılmaz, Süleyman Daşdağ, Mehmet Faruk Oktay, Engin Ulukaya, Merve Erkısa Genel, Funda Emre, Korkut Yeğin","doi":"10.1080/15368378.2025.2577318","DOIUrl":"https://doi.org/10.1080/15368378.2025.2577318","url":null,"abstract":"<p><p>The aim of this study is to investigate the thyroid status of offspring exposed to prenatal 2.45 GHz radiofrequency radiation (RFR). In this study, which is the second phase of our previous study, the thyroids of rats exposed to prenatal 2.45 GHz RFR were examined one year after birth. The mothers of the offspring in the experimental group (<i>n</i> = 8) were exposed to 2.45 GHz RFR (whole-body specific absorption rate (SAR): 12 mW/kg; maximum point SAR: 25 mW/kg) 24 hours per day throughout pregnancy. The mothers in the sham group (<i>n</i> = 8) were kept under the same experimental conditions except for RFR exposure. The offspring in this study were not exposed to RFR after birth and continued their daily lives for one year. When the offspring reached one year of age, they were sacrificed and their thyroids were removed and evaluated. Mann-Whitney U and t tests were used for statistical analysis. Increases in fibrosis (<i>p</i> = 0.038), atypical thyrocytes (<i>p</i> = 0.002) and degenerated follicles (<i>p</i> = 0.007) and colloid reduction (<i>p</i> = 0.002) were found to be significant in the experimental group compared to the sham group. However, the increase in the percentage of apoptosis positive cells (<i>p</i> = 0.006) and H2A.X antibody levels (<i>p</i> = 0.007) showed a statistically significant difference in the experimental group compared to the sham group. This study provides evidence that prenatal exposure to 2.45 GHz RFR can induce persistent histological changes, increase apoptosis, and cause DNA double-strand breaks in thyroid tissue observed one year after birth. These results underscore the importance of further long-term studies to assess developmental risks associated with prenatal RFR exposure.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biological effects on breast cancer cells of strong terahertz waves from a terahertz free-electron laser. 来自太赫兹自由电子激光的强太赫兹波对乳腺癌细胞的生物学影响。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-10-21 DOI: 10.1080/15368378.2025.2577314
Huan Zhou, Xiao-Yu Peng, Weijun Wang, Chengbin Zhao, Peng Zhang, Jie Liu, Peng Li, Julia Li Zhong, Xianqin Luo, Biyong Ren, De-Sheng Pei
{"title":"Biological effects on breast cancer cells of strong terahertz waves from a terahertz free-electron laser.","authors":"Huan Zhou, Xiao-Yu Peng, Weijun Wang, Chengbin Zhao, Peng Zhang, Jie Liu, Peng Li, Julia Li Zhong, Xianqin Luo, Biyong Ren, De-Sheng Pei","doi":"10.1080/15368378.2025.2577314","DOIUrl":"https://doi.org/10.1080/15368378.2025.2577314","url":null,"abstract":"<p><p>It is of great importance to study the biological effects of terahertz (THz) waves on human cancer cells for their potential future applications in cancer therapy. However, only a few examples of distinct biological effects have been reported due to the lack of strong THz radiation sources. Here, we report our preliminary investigation using a strong THz source at 1.56 THz with an average power of ~ 10 W and an average intensity of ~129.1 mW/cm<sup>2</sup> working at a repetition rate of 10 Hz for its macro pulses with duration of ~1 ms and micro pulse duration of ~ 1 ps at a repetition rate of 54.17 MHz from a THz free-electron laser to investigate its biological effects on breast cancer cells in vitro. We observed significant morphological changes in breast cancer cells after 2 hours irradiation and apoptosis after 3 hours irradiation. Most notably, after 4 hours irradiation, we observed obvious cytolysis and the disappearance of most breast cancer cells in the center of the THz beam spot. It is suggested that these biological effects could be attributed mainly to the non-thermal effect of the strong THz waves according to our separate experimental results on the morphological changes of the breast cancer cells induced solely by heat. Our results indicate the potential to leverage the apoptosis and cytolysis of cancer cells induced by strong THz waves for future cancer treatment applications.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145337920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electromagnetic fields and oxidative stress: The link to the development of cancer, neurological diseases, and behavioral disorders. 电磁场和氧化应激:与癌症、神经系统疾病和行为障碍的发展有关。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-10-21 DOI: 10.1080/15368378.2025.2567872
Željko Leković
{"title":"Electromagnetic fields and oxidative stress: The link to the development of cancer, neurological diseases, and behavioral disorders.","authors":"Željko Leković","doi":"10.1080/15368378.2025.2567872","DOIUrl":"https://doi.org/10.1080/15368378.2025.2567872","url":null,"abstract":"<p><strong>Background: </strong>Epidemiological studies suggest an association between exposure to electromagnetic fields (EMFs) and an increased incidence of malignant, cardiovascular, and neurodegenerative diseases. This study aims to elucidate the fundamental principles and plausible mechanisms by which EMFs may influence physiological and pathological processes that lead to disease development.</p><p><strong>Materials and methods: </strong>Published reports of oxidative stress, DNA damage, and disease risk related to EMF exposure were examined. The literature review provided the foundation for building a new conceptual model called the Electromagnetic Pathogenesis (EMP) model.</p><p><strong>Mechanisms: </strong>The EMP model proposes an increase in the probability of electron tunneling through the mitochondrial electron transport chain as the primary pathophysiological mechanism triggered by non-ionizing EMFs. Induced electric fields and quantum tunneling may enhance electron leakage during mitochondrial respiration, which is a major source of free radicals.</p><p><strong>Findings: </strong>There is a deep connection between quantum tunneling, entropy, and Heisenberg's principle. As a direct consequence of Heisenberg's principle, еlectron tunneling is essentially involved in free radical production and entropy generation in cells. Both normal aging and chronic diseases may be considered as the biologic manifestations of increasing entropy. Heisenberg's principle underlies normal aging and sets the limit to life expectancy.</p><p><strong>Social implications: </strong>The human brain, particularly the structural and functional networks that support social communication, is highly vulnerable to oxidative stress associated with EMF exposure. Long-term exposure may negatively affect social and reproductive behaviors in both men and women, potentially contributing to a decline in fertility rates and the acceleration of population aging.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-25"},"PeriodicalIF":1.5,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145338047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the potential of carbon fibre reinforced polymer shielding in protecting male reproductive health from mobile phone radiation. 评估碳纤维增强聚合物屏蔽在保护男性生殖健康免受移动电话辐射方面的潜力。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-10-10 DOI: 10.1080/15368378.2025.2571658
Irmawan Farindra, Soetjipto, Viskasari P Kalanjati, Alya Putri Sakinah, Warda Elmaida Rusdi, Andi Roesbiantoro, Bambang Edi Suwito, Irsandi Rizki Farmananda
{"title":"Assessing the potential of carbon fibre reinforced polymer shielding in protecting male reproductive health from mobile phone radiation.","authors":"Irmawan Farindra, Soetjipto, Viskasari P Kalanjati, Alya Putri Sakinah, Warda Elmaida Rusdi, Andi Roesbiantoro, Bambang Edi Suwito, Irsandi Rizki Farmananda","doi":"10.1080/15368378.2025.2571658","DOIUrl":"https://doi.org/10.1080/15368378.2025.2571658","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluates the protective potential of carbon fibre-reinforced polymer (CFRP) shielding against the adverse effects of 1800 MHz electromagnetic radiation (EMR) from mobile phones on male reproductive indicators in Wistar rats.</p><p><strong>Materials and methods: </strong>Twenty-four adult male Wistar rats were randomly assigned to three groups (<i>n</i> = 8): i. control (no treatment); ii. EMR exposure; iii. EMR exposure with CFRP shielding. The exposure groups were exposed to EMR from an activated 1800 MHz and Specific Absorption Rate (SAR) = 0.897 W/Kg mobile phone for 2 hours/day for 30 days. The shielding consisted of four CFRP prepreg layers (two layers of 210 g/m² and two layers of 450 g/m²), with a total thickness of 2 mm. After the exposure period, sperm analysis (motility, viability, and morphology), serum testosterone, testicular histology, and malondialdehyde (MDA) levels were examined.</p><p><strong>Results: </strong>EMR significantly reduced testosterone levels, sperm viability, sperm morphology, diameter of the seminiferous tubule (ST) (<i>p</i> < 0.05), and interstitial cells of Leydig counts compared to the control groups (<i>p</i> < 0.05). The results also revealed a significant increase in MDA levels in the EMR-exposed group compared to the control group (<i>p</i> < 0.05). Furthermore, the treatment had a positive effect on the CFRP shield group, as these variables were actually better compared to the EMR group without shield.</p><p><strong>Conclusions: </strong>CFRP shielding is proven to reduce the negative impacts of 1800 MHz EMR emitted from mobile phone exposure on sperm quality, testosterone levels, histological testicular, and MDA levels of male Wistar rats.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-12"},"PeriodicalIF":1.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative analysis and trends in the study of the effects of electromagnetic radiation on the nervous system from a bibliometric perspective. 从文献计量学角度研究电磁辐射对神经系统影响的定量分析和趋势。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-10-03 DOI: 10.1080/15368378.2025.2568667
Ketao Liang, Wenying Zhou, Xueqin Li, Jianjun Wu, Dekui Li, Yahui Xie, Xingmin Wei
{"title":"Quantitative analysis and trends in the study of the effects of electromagnetic radiation on the nervous system from a bibliometric perspective.","authors":"Ketao Liang, Wenying Zhou, Xueqin Li, Jianjun Wu, Dekui Li, Yahui Xie, Xingmin Wei","doi":"10.1080/15368378.2025.2568667","DOIUrl":"https://doi.org/10.1080/15368378.2025.2568667","url":null,"abstract":"<p><p>With the rapid development of communication technology, the potential health risk of electromagnetic radiation (EMR) to the nervous system has aroused widespread concern. This study systematically reviews the research progress in the field of EMR-neurological interactions during 2013-2024, revealing its research hotspots and future trends. Based on WOS database, this study adopts bibliometric method combined with visualization technology for multidimensional analysis. The construction of visual maps of countries, institutions, authors, keywords and other elements is realized through CiteSpace and VOSviewer software, which systematically reveals the developmental lineage and knowledge structure of the research field. The study reveals that the field has been growing continuously, with China, Iran and the United States as the core research countries, the Chinese Academy of Military Medical Sciences and other organizations contributing prominently, and Environment International leading the list with an impact factor of 21.90. High-frequency keywords include \"adolescents,\"hippocampus\" and \"synaptic plasticity\", reflecting the focus of research on neurodevelopmental and functional impairments. The study points out that although the mechanism of the neurological effects of electromagnetic radiation has been achieved, its molecular mechanisms and therapeutic interventions still need to be further explored. This study provides a systematic reference for scholars around the world, helps to promote the development of the field of neural effects of electromagnetic radiation, and provides a scientific basis for public health protection.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-14"},"PeriodicalIF":1.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance evaluation and personalized electric field prediction of the deep H1 coil in the human brain based on simulation and machine learning. 基于仿真和机器学习的人脑深H1线圈性能评价与个性化电场预测
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-09-23 DOI: 10.1080/15368378.2025.2561001
Xinhua Tan, Ao Guo, Yifan Wang, Jiasheng Tian, Jian Shi, Yingwei Li
{"title":"Performance evaluation and personalized electric field prediction of the deep H1 coil in the human brain based on simulation and machine learning.","authors":"Xinhua Tan, Ao Guo, Yifan Wang, Jiasheng Tian, Jian Shi, Yingwei Li","doi":"10.1080/15368378.2025.2561001","DOIUrl":"https://doi.org/10.1080/15368378.2025.2561001","url":null,"abstract":"<p><p>Deep transcranial magnetic stimulation (DTMS) has been increasingly used to treat neurological disorders in recent years. However, owing to the complicated configuration of DTMS coils, such as the H1 coil, the electric field induced by it in the personalized human brain is so varied and complex that its transcranial magnetic stimulation performances, especially focusing behavior and depth characteristics, have to be studied and evaluated further before clinical application. Therefore, besides the effects of the excitation frequency of the H1 coils, two types of magnetic shielding blocks (MSBs) with various dimensions were analyzed, and the H1 coil circuit structure with flexible length adjustment and its coil spacing were also investigated in this study. Finally, a machine learning model based on an optimizable tree algorithm was established to rapidly predict the induced electric field in the personalized human brain. Results demonstrated that the half-value depth <i>D</i><sub>1/2</sub> of the electric field induced by the H1 coil could reach 3.67 cm, which was deeper than that by the figure-of-eight (FOE) coil (<1.6 cm), but its focusing (half-value) volume <i>V</i><sub>1/2</sub> was 567.94 cm<sup>3</sup>, larger than that of the FOE coil. After introducing MSBs, reasonably adjusting the coil circuit length and the coil spacing, <i>V</i><sub>1/2</sub> was reduced to 81.748 cm<sup>3</sup>, with a slight increase in <i>D</i><sub>1/2</sub>. The proposed machine learning model exhibited a good prediction performance (<i>R</i><sup>2</sup> = 0.99, etc.) and only took about 0.014 s to finish predicting the induced electric field in the personalized human brain for rapidly evaluating the H1 coil performance in clinical practices.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-26"},"PeriodicalIF":1.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An intelligent model approach for dynamic prediction of magnetized Jeffrey blood flow carrying penta-hybrid nanoparticles in a catheterized electrified arterial annulus. 带五杂化纳米粒子的磁化杰弗里血流动态预测的智能模型方法。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-09-19 DOI: 10.1080/15368378.2025.2561033
Puja Paul, Sanatan Das, Poly Karmakar, Asgar Ali, Tilak Kumar Pal
{"title":"An intelligent model approach for dynamic prediction of magnetized Jeffrey blood flow carrying penta-hybrid nanoparticles in a catheterized electrified arterial annulus.","authors":"Puja Paul, Sanatan Das, Poly Karmakar, Asgar Ali, Tilak Kumar Pal","doi":"10.1080/15368378.2025.2561033","DOIUrl":"https://doi.org/10.1080/15368378.2025.2561033","url":null,"abstract":"<p><p>This research paper presents an artificial intelligence (AI) framework to predict magnetized penta-nanoparticle-enhanced Jeffrey blood flow dynamics in a catheterized electrified arterial annulus. The work addresses critical gaps in modeling non-Newtonian blood rheology with multi-physics interactions. Employing Jeffrey's fluid model to encapsulate the non-Newtonian rheological properties of blood mixed with nanoparticles. This analysis combines diverse factors influencing heat sources, Joule heating, interfacial nanolayers, and porous media drag. The flow system is streamlined via lubrication theory and Debye-Hückel linearization and then solved using homotopy perturbation method (HPM). Visualization of indispensable flow metrics is conducted using tools in Mathematica and Matlab. Computational results indicate electro-osmotic forces significantly alter the streaming patterns of penta-hybrid nanoparticle-infused blood in catheterized arterial geometry. Blood temperature lowers in the catheterized regions for the expanded thickness of nanolayer, and the axial blood pressure gradient elevates with an upsurge in the electro-osmotic factor while wall shear stress (WSS) abates. Heat transfer coefficient (HTC) improves with thicker nanolayers. AI-driven artificial neural network (ANN) model achieves 97-100% accuracy in predicting WSS and HTC. The research findings highlight potential improvements in patient-specific treatment strategies and contribute to the broader field of biomedical engineering by enhancing the efficacy and precision of non-invasive therapies.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-38"},"PeriodicalIF":1.5,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interaction between variable magnetic field with low magnetic induction value and body tattoos - a preliminary observational single center study. 低磁感应强度变磁场与人体文身的相互作用——单中心观察性初步研究。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-09-16 DOI: 10.1080/15368378.2025.2562431
Jarosław Pasek, Sebastian Szajkowski, Grzegorz Cieślar
{"title":"Interaction between variable magnetic field with low magnetic induction value and body tattoos - a preliminary observational single center study.","authors":"Jarosław Pasek, Sebastian Szajkowski, Grzegorz Cieślar","doi":"10.1080/15368378.2025.2562431","DOIUrl":"https://doi.org/10.1080/15368378.2025.2562431","url":null,"abstract":"<p><strong>Purpose: </strong>Low-induction variable magnetic fields are widely used in various fields of medicine. However, it is worth raising the issue whether treatments using low-induction variable magnetic fields applied to patients can affect the condition of tattooed skin.</p><p><strong>Methods: </strong>In the study, 24 volunteers were enrolled (12 men and 12 women) their age range was 30-60 years (average age: 43 years), they were assigned to two groups. The study group included people with a black ink (7 people) or colored (5 people) tattoo on the skin of the upper limb. The control group included 12 participants without tattoos. The participants were exposed to variable magnetic field with low magnetic induction value applied to the upper limb area, in form of magnetostimulation procedures performed once a day, 5 days a week for 3 weeks. Using an original questionnaire, it was assessed whether the subjects experienced any disturbing symptoms related to the physical treatments during and after the treatments.</p><p><strong>Results: </strong>After the magnetic stimulation, 2 patients from the study group (with a colored tattoo) indicated that during the procedures they felt a feeling of warmth and slight itching of the skin in the place of exposure to magnetic field. In the control group, no side effects of the procedures were noted. Dermatological evaluation did not reveal any pathological changes in the skin area exposed to magnetic field in any participant from both groups.</p><p><strong>Conclusions: </strong>Treatments using low-induction variable magnetic fields in people with tattoos did not show any significant adverse effects on the skin in the tattoo area exposed to the magnetic field.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of spectral properties of the bovine serum albumin complexes with acridine orange and methylene blue under the effect of millimeter range electromagnetic waves. 毫米波作用下牛血清白蛋白与吖啶橙和亚甲基蓝配合物光谱特性的比较研究。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-09-09 DOI: 10.1080/15368378.2025.2558669
A P Antonyan, M A Shahinyan, M S Mikaelyan, A H Karapetyan, V P Kalantaryan, P O Vardevanyan
{"title":"Comparative study of spectral properties of the bovine serum albumin complexes with acridine orange and methylene blue under the effect of millimeter range electromagnetic waves.","authors":"A P Antonyan, M A Shahinyan, M S Mikaelyan, A H Karapetyan, V P Kalantaryan, P O Vardevanyan","doi":"10.1080/15368378.2025.2558669","DOIUrl":"https://doi.org/10.1080/15368378.2025.2558669","url":null,"abstract":"<p><p>Effect of millimeter range electromagnetic waves (MM EMW) with the frequency 51.8 GHz on the interaction of DNA-specific ligands-intercalators acridine orange (AO) and methylene blue (MB) with bovine serum albumin (BSA) has been studied. The measurements were implemented by the spectroscopic methods that open new opportunities for such goals. The methods of absorption, differential and fluorescence spectroscopies were applied. The obtained data permit revealing several peculiarities of MM EMW effect on the interaction of these ligands with BSA, as well as possible sites and modes for the binding. AO and MB were found out to bind to BSA by two modes, moreover, under the effect of MM EMW, one of these modes for MB disappears. The values of the quenching constant - K<sub>SV</sub> were determined for the types that compose 4.7⋅10<sup>4</sup> and 9.2⋅10<sup>4</sup> L/mole for non-irradiated and 4.6⋅10<sup>4</sup> and 11.0⋅10<sup>4</sup> L/mole for irradiated complexes AO-BSA, respectively. For the non-irradiated complexes MB-BSA the values of K<sub>SV</sub> were equal to 4.0⋅10<sup>4</sup> and 0.87⋅10<sup>4</sup> L/mole, respectively. Because of the irradiation, the first type of the binding disappears, while for the second type the value 0.43⋅10<sup>4</sup> L/mole was obtained. It was also revealed that MM EMW invokes structural transformations in BSA molecule that touch those sites to which AO and MB bind. Moreover, for AO it results in an increase of preferable binding to this site; though, for MB, vice versa, it leads to the disappearance of stronger (specific) binding mode, while the electrostatic interaction appears for both non-irradiated and irradiated protein.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lawn bowling and potential interference of a cardiovascular implantable electronic device (CIED): case report. 草地保龄球与心血管植入式电子装置(CIED)的潜在干扰:1例报告。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-09-02 DOI: 10.1080/15368378.2025.2553647
E De Waegeneer, B Corteville, L Braeckman
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