Electromagnetic Biology and Medicine最新文献

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Activating Transcription Factor 4 regulation of radiofrequency radiation-induced ferroptosis in osteoblasts. 激活转录因子4对射频辐射诱导的成骨细胞铁下垂的调控。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-08-19 DOI: 10.1080/15368378.2025.2547799
Haiying Wang, Weijin Zou, Caihua Ding, Yi Cao
{"title":"Activating Transcription Factor 4 regulation of radiofrequency radiation-induced ferroptosis in osteoblasts.","authors":"Haiying Wang, Weijin Zou, Caihua Ding, Yi Cao","doi":"10.1080/15368378.2025.2547799","DOIUrl":"10.1080/15368378.2025.2547799","url":null,"abstract":"<p><p>Given the ubiquitous presence of radiofrequency (RF) radiation sources in modern environments, concerns have been raised regarding their cytotoxic effects on osteoblasts and potential implications for skeletal health. This study investigated the molecular mechanisms underlying these effects, focusing on ferroptosis, a form of regulated cell death implicated in bone pathologies, and the role of Activating Transcription Factor 4 (ATF4). Through comprehensive bioinformatic analyses of public gene expression databases, we identified significant correlations between differentially expressed genes and biological processes associated with lipid metabolism and ferroptosis. MC3T3-E1 osteoblasts were subjected to systematic evaluation under four distinct experimental conditions: a sham-exposed control group and three treatment groups exposed to calibrated RF radiation intensities - low (LRF, 50μW/cm<sup>2</sup>), moderate (MRF, 150μW/cm<sup>2</sup>), and high (HRF,450μW/cm<sup>2</sup>). To elucidate the molecular mechanisms underlying RF-induced ferroptosis, both ATF4 knockdown and overexpression experiments were performed. The findings indicated that RF radiation at 150μW/cm<sup>2</sup> elicited the most pronounced effects, characterized by reduced osteoblast viability, elevated lipid peroxidation, disrupted redox balance, impaired mitochondrial function, and disturbances in iron homeostasis. Notably, <i>Atf4</i> knockdown exacerbated these deleterious effects, while its overexpression conferred protection against RF radiation-induced cellular damage. This study demonstrates the crucial role of ATF4 modulation in RF radiation-induced ferroptosis in osteoblasts, a process potentially contributing to bone disorders such as osteoporosis and impaired fracture healing. These findings suggest that targeting ATF4 may represent a promising therapeutic approach to mitigate the effects of RF radiation on bone health, thereby opening new avenues for intervention in environmentally influenced skeletal disorders.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-15"},"PeriodicalIF":1.5,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144884231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined effects of agomelatine and 2600 MHz radiofrequency field on inflammation induced by chronic lipopolysaccharide administration. 阿戈美拉汀联合2600 MHz射频场对慢性脂多糖诱导炎症的影响。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-08-12 DOI: 10.1080/15368378.2025.2545871
Sinem Oruç, Sevilay Günay, Bahriye Sirav Aral, Yavuz Erden, Mahmud Mustafa Özkut, Kayhan Ateş, Gökçen Özdemir, Ersen Eraslan
{"title":"Combined effects of agomelatine and 2600 MHz radiofrequency field on inflammation induced by chronic lipopolysaccharide administration.","authors":"Sinem Oruç, Sevilay Günay, Bahriye Sirav Aral, Yavuz Erden, Mahmud Mustafa Özkut, Kayhan Ateş, Gökçen Özdemir, Ersen Eraslan","doi":"10.1080/15368378.2025.2545871","DOIUrl":"https://doi.org/10.1080/15368378.2025.2545871","url":null,"abstract":"<p><p>The aim of this study is to investigate the potential synergistic effects of agomelatine(AGM) and 2600 MHz radiofrequency(RF) field exposure on inflammation induced by chronic lipopolysaccharide(LPS) administration in rats. A total of 49 female Wistar albino rats were randomly divided into 7 groups(<i>n</i> = 7 per group): Control, Sham, LPS, LPS+AGM,LPS+RF,AGM+RF, and LPS+AGM+RF. Animals in the RF groups were exposed to a 2600 MHz field (1 h/day for 15 days). The whole-body averaged SAR was calculated to be 0.637 W/kg, while the localized SAR values were found to be 1.27 W/kg for 1 g and 0.91 W/kg for 10 g of brain tissue at a frequency of 2600 MHz. Chronic LPS administration(1 mg/kg/day for 15 days) successfully induced a systemic inflammatory state. The most significant finding was observed in plasma IL-6 levels. While AGM or RF exposure alone did not significantly alter IL-6 levels in LPS-treated animals, the combined treatment of LPS+AGM+RF resulted in a substantial and statistically significant decrease in plasma IL-6 compared to the sham group(<i>p</i> < 0.001). This represents a large-magnitude effect (Cohen's d = 1.59), suggesting a potent anti-inflammatory action of the combined therapy. In contrast, plasma IL-1β and TNF-α levels showed no statistically significant differences among any of the groups. In the hypothalamus, chronic LPS exposure was associated with a downregulation of MAP kinase signaling pathways (ERK, JNK), indicative of endotoxin tolerance, and with reduced NF-κB level. This study provides novel evidence that 2600 MHz RF, when combined with AGM, may exert a powerful anti-inflammatory effect, highlighting a potential therapeutic interaction that warrants further investigation.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring research trends in health effects of 5G antennas: a bibliometric analysis. 探索5G天线对健康影响的研究趋势:文献计量学分析。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-08-04 DOI: 10.1080/15368378.2025.2539147
Ahmet Turgut, Begum Korunur Engiz
{"title":"Exploring research trends in health effects of 5G antennas: a bibliometric analysis.","authors":"Ahmet Turgut, Begum Korunur Engiz","doi":"10.1080/15368378.2025.2539147","DOIUrl":"https://doi.org/10.1080/15368378.2025.2539147","url":null,"abstract":"<p><p>To better understand the developments and trends of studies on the health impacts of 5th Generation (5 G) antennas, a bibliometric analysis of the literature published in the Web of Science database from 2012 to 2025 was conducted. Before the analysis, the dosimetric quantities \"specific absorption rate (SAR)\" and \"power density (Sab)\" used in the examination of the health impacts of antennas were thoroughly defined, and their required limits were provided. Subsequently, information visualization technology was utilized to investigate the yearly distribution of literature, author contributions and collaboration, productive and influential institutions and countries/territories, co-citation analysis, and keyword co-occurrence. However, anticipated publication and citation numbers for the coming years (2025-2029) were predicted regarding the potential health impacts of 5 G antennas using artificial intelligence-assisted forecasting methods. There has been a considerable increase in studies related to health impacts measured by SAR and Sab dosimetric quantities over the last five years, in line with the number of articles published on 5 G antennas. Despite this, no bibliometric analysis has been done so far on the health impact of 5 G antennas below and above 6 GHz. The data presented in this bibliometric study to fill the gap on this subject will provide a better understanding of the health impacts and unique insights to offer good research guidance on 5 G antennas and their attributed adverse health impacts.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-20"},"PeriodicalIF":1.5,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low frequency magnetic field exposure and neurodegenerative disease: systematic review of animal studies. 低频磁场暴露与神经退行性疾病:动物研究的系统回顾。
IF 1.5 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-08-03 DOI: 10.1080/15368378.2025.2540435
Rianne Stam
{"title":"Low frequency magnetic field exposure and neurodegenerative disease: systematic review of animal studies.","authors":"Rianne Stam","doi":"10.1080/15368378.2025.2540435","DOIUrl":"https://doi.org/10.1080/15368378.2025.2540435","url":null,"abstract":"<p><p>Epidemiological studies have found an association between occupational exposure to low frequency magnetic fields and the occurrence of motor neuron disease and Alzheimer's disease. No association has been found for Parkinson's disease and the evidence for multiple sclerosis is insufficient. Animal models studying the effects of low frequency magnetic fields on neurodegenerative disease induction or progression could provide more evidence on causation and the underlying mechanisms. A systematic search and review was conducted of peer-reviewed research articles involving animal experiments on the effects of low frequency magnetic field exposure on behavioural and neuroanatomical outcomes relevant for neurodegenerative diseases in humans. Firstly, experimental studies in <i>naive animals</i> do not support a causal relationship between exposure to low frequency magnetic fields and the induction of neuropathology relevant for Alzheimer's disease, but the number of studies relevant for motor neuron disease, multiple sclerosis and Parkinson's disease is too limited to draw conclusions. Secondly, experimental studies in <i>existing animal models for neurodegenerative disease</i> support a therapeutic (beneficial) effect of low frequency magnetic field treatment on behavioural and neuroanatomical abnormalities relevant for dementia (including Alzheimer's disease), multiple sclerosis and Parkinson's disease and no effect on disease progression in models relevant for motor neuron disease.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-15"},"PeriodicalIF":1.5,"publicationDate":"2025-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genotoxic and histopathological effects of 6 GHz radiofrequency electromagnetic radiation on rat liver tissue. 6ghz射频电磁辐射对大鼠肝组织的遗传毒性和组织病理学影响。
IF 1.6 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-07-22 DOI: 10.1080/15368378.2025.2534381
Nermin Seda Ilgaz, Yasin Karamazı, Mustafa Emre, Tuğba Toyran, Özdem Karaoğlan, Toygar Emre, Meltem Dönmez Kutlu, Hale Öksüz Üçkayabaşı, Çağatay Aydın, M Bertan Yılmaz
{"title":"Genotoxic and histopathological effects of 6 GHz radiofrequency electromagnetic radiation on rat liver tissue.","authors":"Nermin Seda Ilgaz, Yasin Karamazı, Mustafa Emre, Tuğba Toyran, Özdem Karaoğlan, Toygar Emre, Meltem Dönmez Kutlu, Hale Öksüz Üçkayabaşı, Çağatay Aydın, M Bertan Yılmaz","doi":"10.1080/15368378.2025.2534381","DOIUrl":"https://doi.org/10.1080/15368378.2025.2534381","url":null,"abstract":"<p><p>In this study, the genotoxic and histopathological effects of 6 GHz (0.065 W/kg) Radiofrequency-Electromagnetic Radiation (RF-EMR) on rat liver tissue were investigated. Sham (control) and Radiofrequency Radiation (RFR) groups were formed with 10 adult male rats in each group. Rats in the sham group received no treatment. Rats in the RFR group were exposed to 6 GHz RF-EMR for 4 h/day for 42 days. Immediately after the completion of the exposure, the rats in both groups were sacrificed and liver tissues were removed. Comet Test was performed to determine the genotoxic effect in the samples. Masson Trichrome and Hematoxylin Eosin staining methods were applied histopathologically. According to the Comet Analysis results, the genetic damage index (GDI) and damaged cell percentage (DCP) of the RFR group were higher than the sham group, but this difference was not statistically significant (<i>p</i> > 0.05). In histopathologic examinations, portal inflammation, single cell necrosis, vascularity and congestion were more prominent in the RFR group compared to the sham group. In our study, it was shown that 6 GHz RF-EMR can cause histopathologic and DNA level changes in rat liver tissue. As a result of the literature review, no prior studies have specifically examined the genotoxic and histopathological effects of 6 GHz RF-EMR. This makes our study important as it addresses the biological impacts of the 6 GHz frequency band.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-12"},"PeriodicalIF":1.6,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Numerical analysis of power- and temperature-controlled radiofrequency ablation in varicose vein treatment. 功率和温度控制射频消融治疗静脉曲张的数值分析。
IF 1.6 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-07-17 DOI: 10.1080/15368378.2025.2534380
Xiaohua Song, Ning Wu, Zhishuai Zhang, Qun Nan
{"title":"Numerical analysis of power- and temperature-controlled radiofrequency ablation in varicose vein treatment.","authors":"Xiaohua Song, Ning Wu, Zhishuai Zhang, Qun Nan","doi":"10.1080/15368378.2025.2534380","DOIUrl":"https://doi.org/10.1080/15368378.2025.2534380","url":null,"abstract":"<p><p>This study investigates radiofrequency ablation (RFA) parameters for varicose vein treatment using a three-dimensional mathematical model operating at 470 kHz. The model evaluates how power settings, temperature thresholds, blood flow velocity, and electrode spacing influence therapeutic efficacy and tissue safety. Findings demonstrate that higher power and temperature settings, combined with lower blood flow rates, enhance venous wall heating while minimizing extraluminal tissue damage. Stagnant blood flow optimizes thermal energy delivery, and adjusting electrode spacing reduces the required number of ablations. Temperature-controlled radiofrequency ablation has a controlled electrode temperature for better temperature delivery. This study provides actionable guidance for clinicians to tailor RFA protocols that emphasize management and electrode configuration adjustments for safer and more efficient outcomes in varicose vein treatment.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-11"},"PeriodicalIF":1.6,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective effects of quercetin against 3.5 GHz RF radiation-induced thyroid dysfunction and oxidative stress in rats. 槲皮素对3.5 GHz射频辐射诱导大鼠甲状腺功能障碍和氧化应激的保护作用。
IF 1.6 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-07-08 DOI: 10.1080/15368378.2025.2528732
Hava Bektas, Burcu Buse Bese Akgun, Serife Cakir, Semih Dogu, Bedia Ahnas
{"title":"Protective effects of quercetin against 3.5 GHz RF radiation-induced thyroid dysfunction and oxidative stress in rats.","authors":"Hava Bektas, Burcu Buse Bese Akgun, Serife Cakir, Semih Dogu, Bedia Ahnas","doi":"10.1080/15368378.2025.2528732","DOIUrl":"https://doi.org/10.1080/15368378.2025.2528732","url":null,"abstract":"<p><p>The global expansion of 5 G communication networks has heightened concerns about the biological effects of high-frequency radiofrequency (RF) radiation, particularly on endocrine organs such as the thyroid gland. This study investigated the effects of 3.5 GHz RF radiation on thyroid hormone levels and oxidative stress markers in male Wistar rats and assessed the potential protective role of quercetin, a natural antioxidant. Twenty-eight rats were randomly assigned to four groups: Sham, RF, Quercetin, and RF + Quercetin. RF exposure was administered at 3.5 GHz (2 W) for 2 hours/day, 5 days/week, for 30 days. Quercetin (20 mg/kg) was administered intraperitoneally. Serum levels of T3, T4, and TSH, as well as thyroid tissue levels of TAS, TOS, GSH, and MDA, were analyzed using ELISA. RF exposure significantly decreased T3 and T4, increased TSH, elevated MDA and TOS, and reduced TAS and GSH levels. Quercetin treatment showed trends toward reversing some of these effects, although not all changes reached statistical significance. SAR simulations confirmed higher energy absorption in the thyroid region (average SAR: 1.128 W/kg). These findings suggest that 3.5 GHz RF radiation may impair thyroid function and redox homeostasis, and that quercetin may exert limited biochemical protection, though further studies are needed to confirm its efficacy. Further long-term molecular studies are warranted to elucidate the mechanisms involved.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-12"},"PeriodicalIF":1.6,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and performance evaluation of magnetic hyperthermia instrument with embedded PI control. 嵌入式PI控制磁热疗仪的设计与性能评价。
IF 1.6 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-06-29 DOI: 10.1080/15368378.2025.2524547
Mou Chatterjee, Sandip Pal
{"title":"Design and performance evaluation of magnetic hyperthermia instrument with embedded PI control.","authors":"Mou Chatterjee, Sandip Pal","doi":"10.1080/15368378.2025.2524547","DOIUrl":"https://doi.org/10.1080/15368378.2025.2524547","url":null,"abstract":"<p><p>Hyperthermia is a non-invasive localized heating technique that has proven to be an efficient cancer treatment method. Hyperthermia therapy needs precise temperature control to ensure delivery of the proper thermal dose, causing minimum damage to the neighboring healthy tissues. This work reports the indigenous development of a custom-designed hyperthermia instrument. An advanced RISC machine (ARM)-based embedded closed-loop proportional-integral (PI) controller is developed for controlling the temperature. As per the applied methodology, the DC bias of a Mazzilli oscillator-based half-bridge inverter is controlled through the controller. The PI controller reads the hyperthermia system temperature using an infrared (IR) radiation thermometer and generates an analog output accordingly. This, in turn, changes the amplitude of the alternating magnetic field (AMF), thus controlling the temperature of the magnetic nanoparticles (MNPs). Its potential has been explored for <i>in vitro</i> hyperthermia studies. <i>In vitro</i> experiments have been carried out successfully with the custom-designed heater and controller assembly utilizing commercial non-invasive temperature measurement with a standard deviation of about 0.3°C and overshoot within the hyperthermia temperature range (3°C). The developed system has also obtained a satisfactory value of specific absorption rate (SAR). This paper infers the feasibility of the indigenously developed circuit and the related controller for hyperthermia therapy and preclinical studies. This system can be used for clinical applications with suitable customizations.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-15"},"PeriodicalIF":1.6,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of 60 Hz magnetic fields on social feeding behavior of npr-1 receptor mutants in Caenorhabditis elegans. 60 Hz磁场对秀丽隐杆线虫npr-1受体突变体社会摄食行为的影响
IF 1.6 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-06-26 DOI: 10.1080/15368378.2025.2523773
Makiko Kakikawa, Ami Kenmochi, Sotoshi Yamada
{"title":"Effect of 60 Hz magnetic fields on social feeding behavior of <i>npr-1</i> receptor mutants in <i>Caenorhabditis elegans</i>.","authors":"Makiko Kakikawa, Ami Kenmochi, Sotoshi Yamada","doi":"10.1080/15368378.2025.2523773","DOIUrl":"https://doi.org/10.1080/15368378.2025.2523773","url":null,"abstract":"<p><p>Previous studies indicated that magnetic fields (MF) could alter the conformation of membrane proteins such as some drug influx transporters and affect their function. In this study, we focused on two mutants of <i>npr-1</i> receptor gene related to feeding behavior in <i>Caenorhabditis elegans</i> (<i>C. elegans)</i> to investigate the effect of 60 Hz, 50 mT MF on a receptor in neurotransmission. The wild-type laboratory strain Bristol N2 in <i>C. elegans</i> forages solitary on the <i>E. coli</i> lawn, whereas <i>npr-1</i> mutant of N2 aggregate on food and take on social feeding behavior because of its altered function. Under MF exposure, the number of aggregates exhibiting social feeding behavior on two mutants, IM222 and DA609, was decreased by 40% and 25%, respectively. Meanwhile, <i>npr-1</i> is not involved in the behavior to attractant diacetyl in <i>C. elegans</i>, and the moving speed and reach rate to attractant in two mutants was not affected by MF exposure for up to 90 min. The results indicate that MF can affect the altered function of NPR-1 in mutant strains and partially change the feeding behaviour of the <i>npr-1</i> mutants from social to solitary. Furthermore, considering the position of these amino acid substitutions in NPR-1 mutant receptors, the extracellular parts of membrane protein may be more affected by MF than the transmembrane part.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-9"},"PeriodicalIF":1.6,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Greater prevalence of symptoms associated with higher exposures to mobile phone base stations in a hilly, densely populated city in Mizoram, India. 在印度米佐拉姆邦一个人口稠密的丘陵城市,与移动电话基站接触较多有关的症状患病率较高。
IF 1.6 4区 生物学
Electromagnetic Biology and Medicine Pub Date : 2025-06-08 DOI: 10.1080/15368378.2025.2513900
Lalhruaitluangi Sailo, Laldinpuii, Mary Zosangzuali, Steven Weller, C Lalfamkima Varte, Lalchhandami Tochhawng, Julie E McCredden, Zothansiama
{"title":"Greater prevalence of symptoms associated with higher exposures to mobile phone base stations in a hilly, densely populated city in Mizoram, India.","authors":"Lalhruaitluangi Sailo, Laldinpuii, Mary Zosangzuali, Steven Weller, C Lalfamkima Varte, Lalchhandami Tochhawng, Julie E McCredden, Zothansiama","doi":"10.1080/15368378.2025.2513900","DOIUrl":"https://doi.org/10.1080/15368378.2025.2513900","url":null,"abstract":"<p><p>Members of the scientific community and the general public are raising concerns about the potential health and environmental effects of radio-frequency electromagnetic fields (RF-EMF) for those living nearby mobile phone base stations (MPBS). This study examined the impact of RF-EMF (900-1900 MHz) on symptoms spanning four health categories: mood-energy, cognitive-sensory, inflammatory, and anatomical issues. A questionnaire identifying health symptoms within these categories, was given to 183 highly exposed and 126 reference residents, matched on demographics. While years of residing near the MPBS influenced the prevalence of some symptoms, proximity to the base station and higher levels of exposure (measured using power density) influenced the prevalence of many of the symptoms. A higher proportion of symptoms was found in residents who were either living within 50 meters of a MPBS or who were exposed to power densities of 5-8 mW/m<sup>2</sup>, for all four health categories. This relationship between exposure level and symptom prevalence was further influenced by age, daily mobile phone use (over 5 h per day), and lifestyle factors, for certain symptoms. Hierarchical regression analysis revealed that level of exposure (power density) was the only factor contributing to the number of symptoms experienced by residents, for all four health categories. An unexpected finding was that among the more highly exposed residents, the younger individuals (under 40 years) reported more inflammation related issues than older individuals. These results underscore the need to inform policymakers regarding the benefits of adopting a precautionary approach to potential risks associated with RF-EMF exposures from MPBS.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-20"},"PeriodicalIF":1.6,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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