The use of electromagnetic transduction therapy in patients with chronic myofascial pain: A pilot double-blinded randomised controlled trial.

IF 1.5 4区 生物学 Q3 BIOLOGY
Electromagnetic Biology and Medicine Pub Date : 2025-01-01 Epub Date: 2025-02-24 DOI:10.1080/15368378.2025.2466491
Derek King Wai Yau, Ara Cheuk Yin Li, Hoi Yim Cheung, Ning Cheung, Anna Lee
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Abstract

Electromagnetic transduction therapy (EMTT) is a non-invasive magnetic therapy with high oscillating electromagnetic field power. This pilot randomised controlled trial (ChiCTR1900021031) evaluated EMTT's potential efficacy in relieving pain and other non-symptomatic aspects of chronic myofascial pain (CMP). Forty patients with moderate-to-severe CMP were randomised into treatment (real-EMTT) or control (sham-EMTT) group, and received eight sessions of 20-minute real or sham EMTT over four weeks. Generalised estimating equation was used to estimate changes in outcomes, including Numerical Rating Scale (NRS), Brief Pain Inventory Interference Scale (BPI-IS), Beck Depression Inventory (BDI), and Patient Global Impression of Change scale (PGIC) before and up to 6 months after treatment. Recruitment and compliance rates (95% confidence interval) were 39.6% (30.0%-49.8%) and 87.5% (73.2%-95.8%), respectively. There were no significant changes in NRS, BPI-IS and BDI over time (group*time p = 0.929, p = 0.949 and p = 0.608, respectively), and PGIC also did not differ between groups over time (all p > 0.050). Based on the variability of the NRS and non-compliance rate of the patients included in this pilot trial, a total sample size of 148 is required to achieve 80% power if a clinically meaningful reduction in NRS after EMTT treatment is 1.0 (with a superiority margin of 0.3).

使用电磁传导治疗慢性肌筋膜疼痛患者:一项双盲随机对照试验。
电磁转导治疗(EMTT)是一种具有高振荡电磁场功率的无创磁疗法。这项随机对照试验(ChiCTR1900021031)评估了EMTT在缓解疼痛和慢性肌筋膜疼痛(CMP)的其他无症状方面的潜在疗效。40例中重度CMP患者随机分为治疗组(real-EMTT)或对照组(sham-EMTT),在四周内接受8次20分钟的真实或虚假EMTT治疗。使用广义估计方程来估计结果的变化,包括数值评定量表(NRS)、短暂疼痛量表干扰量表(BPI-IS)、贝克抑郁量表(BDI)和患者总体印象变化量表(PGIC)在治疗前和治疗后6个月。招募率和依从率(95%置信区间)分别为39.6%(30.0% ~ 49.8%)和87.5%(73.2% ~ 95.8%)。NRS、BPI-IS、BDI随时间变化无统计学意义(组*时间p = 0.929、p = 0.949、p = 0.608), PGIC随时间变化无统计学意义(p均为0.050)。基于NRS的可变性和纳入该试点试验的患者的不依从率,如果EMTT治疗后临床有意义的NRS降低为1.0(优势边际为0.3),则需要148个总样本量才能达到80%的有效性。
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来源期刊
CiteScore
3.60
自引率
11.80%
发文量
33
审稿时长
>12 weeks
期刊介绍: Aims & Scope: Electromagnetic Biology and Medicine, publishes peer-reviewed research articles on the biological effects and medical applications of non-ionizing electromagnetic fields (from extremely-low frequency to radiofrequency). Topic examples include in vitro and in vivo studies, epidemiological investigation, mechanism and mode of interaction between non-ionizing electromagnetic fields and biological systems. In addition to publishing original articles, the journal also publishes meeting summaries and reports, and reviews on selected topics.
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