Journal of X-Ray Science and Technology最新文献_第2页

Feasibility exploration of myocardial blood flow synthesis from a simulated static myocardial computed tomography perfusion via a deep neural network. 通过深度神经网络从模拟静态心肌计算机断层扫描灌注合成心肌血流的可行性探索。

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-03 DOI: 10.1177/08953996251317412

Jun Dong, Runjianya Ling, Zhenxing Huang, Yidan Xu, Haiyan Wang, Zixiang Chen, Meiyong Huang, Vladimir Stankovic, Jiayin Zhang, Zhanli Hu

{"title":"Feasibility exploration of myocardial blood flow synthesis from a simulated static myocardial computed tomography perfusion via a deep neural network.","authors":"Jun Dong, Runjianya Ling, Zhenxing Huang, Yidan Xu, Haiyan Wang, Zixiang Chen, Meiyong Huang, Vladimir Stankovic, Jiayin Zhang, Zhanli Hu","doi":"10.1177/08953996251317412","DOIUrl":"https://doi.org/10.1177/08953996251317412","url":null,"abstract":"Background:: Myocardial blood flow (MBF) provides important diagnostic information for myocardial ischemia. However, dynamic computed tomography perfusion (CTP) needed for MBF involves multiple exposures, leading to high radiation doses.Objectives:: This study investigated synthesizing MBF from simulated static myocardial CTP to explore dose reduction potential, bypassing the traditional dynamic input function.Methods:: The study included 253 subjects with intermediate-to-high pretest probabilities of obstructive coronary artery disease (CAD). MBF was reconstructed from dynamic myocardial CTP. A deep neural network (DNN) converted simulated static CTP into synthetic MBF. Beyond the usual image quality evaluation, the synthetic MBF was segmented and a clinical functional assessment was conducted, with quantitative analysis for consistency and correlation.Results:: Synthetic MBF closely matched the referenced MBF, with an average structure similarity (SSIM) of 0.87. ROC analysis of ischemic segments showed an area under curve (AUC) of 0.915 for synthetic MBF. This method can theoretically reduce the radiation dose for MBF significantly, provided satisfactory static CTP is obtained, reducing reliance on high time resolution of dynamic CTP.Conclusions:: The proposed method is feasible, with satisfactory clinical functionality of synthetic MBF. Further investigation and validation are needed to confirm actual dose reduction in clinical settings.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"8953996251317412"},"PeriodicalIF":1.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing lung cancer diagnosis: Combining 3D auto-encoders and attention mechanisms for CT scan analysis. 推进肺癌诊断：结合三维自动编码器和注意力机制进行 CT 扫描分析。

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-01 Epub Date: 2025-01-28 DOI: 10.1177/08953996241313120

Meng Wang, Zi Yang, Ruifeng Zhao

{"title":"Advancing lung cancer diagnosis: Combining 3D auto-encoders and attention mechanisms for CT scan analysis.","authors":"Meng Wang, Zi Yang, Ruifeng Zhao","doi":"10.1177/08953996241313120","DOIUrl":"10.1177/08953996241313120","url":null,"abstract":"ObjectiveThe goal of this study is to assess the effectiveness of a hybrid deep learning model that combines 3D Auto-encoders with attention mechanisms to detect lung cancer early from CT scan images. The study aims to improve diagnostic accuracy, sensitivity, and specificity by focusing on key features in the scans.Materials and methodsA hybrid model was developed that combines feature extraction using 3D Auto-encoder networks with attention mechanisms. First, the 3D Auto-encoder model was tested without attention, using feature selection techniques such as RFE, LASSO, and ANOVA. This was followed by evaluation using several classifiers: SVM, RF, GBM, MLP, LightGBM, XGBoost, Stacking, and Voting. The model's performance was evaluated based on accuracy, sensitivity, F1-Score, and AUC-ROC. After that, attention mechanisms were added to help the model focus on important areas in the CT scans, and the performance was re-assessed.ResultsThe 3D Auto-encoder model without attention achieved an accuracy of 93% and sensitivity of 89%. When attention mechanisms were added, the performance improved across all metrics. For example, the accuracy of SVM increased to 94%, sensitivity to 91%, and AUC-ROC to 0.96. Random Forest (RF) also showed improvements, with accuracy rising to 94% and AUC-ROC to 0.93. The final model with attention improved the overall accuracy to 93.4%, sensitivity to 90.2%, and AUC-ROC to 94.1%. These results highlight the important role of attention in identifying the most relevant features for accurate classification.ConclusionsThe proposed hybrid deep learning model, especially with the addition of attention mechanisms, significantly improves the early detection of lung cancer. By focusing on key features in the CT scans, the attention mechanism helps reduce false negatives and boosts overall diagnostic accuracy. This approach has great potential for use in clinical applications, particularly in the early-stage detection of lung cancer.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"376-392"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An efficient and high-quality scheme for cone-beam CT reconstruction from sparse-view data.

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-01 Epub Date: 2025-02-04 DOI: 10.1177/08953996241313121

Shunli Zhang, Mingxiu Tuo, Siyu Jin, Yikuan Gu

{"title":"An efficient and high-quality scheme for cone-beam CT reconstruction from sparse-view data.","authors":"Shunli Zhang, Mingxiu Tuo, Siyu Jin, Yikuan Gu","doi":"10.1177/08953996241313121","DOIUrl":"10.1177/08953996241313121","url":null,"abstract":"Computed tomography (CT) is capable of generating detailed cross-sectional images of the scanned objects non-destructively. So far, CT has become an increasingly vital tool for 3D modelling of cultural relics. Compressed sensing (CS)-based CT reconstruction algorithms, such as the algebraic reconstruction technique (ART) regularized by total variation (TV), enable accurate reconstructions from sparse-view data, which consequently reduces both scanning time and costs. However, the implementation of the ART-TV is considerably slow, particularly in cone-beam reconstruction. In this paper, we propose an efficient and high-quality scheme for cone-beam CT reconstruction based on the traditional ART-TV algorithm. Our scheme employs Joseph's projection method for the computation of the system matrix. By exploiting the geometric symmetry of the cone-beam rays, we are able to compute the weight coefficients of the system matrix for two symmetric rays simultaneously. We then employ multi-threading technology to speed up the reconstruction of ART, and utilize graphics processing units (GPUs) to accelerate the TV minimization. Experimental results demonstrate that, for a typical reconstruction of a 512 × 512 × 512 volume from 60 views of 512 × 512 projection images, our scheme achieves a speedup of 14 × compared to a single-threaded CPU implementation. Furthermore, high-quality reconstructions of ART-TV are obtained by using Joseph's projection compared with that using traditional Siddon's projection.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"420-435"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on the influence of square fiber diameter quality on the optical characteristics of lobster eye X-ray micro pore optics.

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-01 Epub Date: 2025-01-27 DOI: 10.1177/08953996241306697

Yang Cao, Honggang Wang, Yanan Wang, Longhui Li, Yunsheng Qian, Yizheng Lang

{"title":"Study on the influence of square fiber diameter quality on the optical characteristics of lobster eye X-ray micro pore optics.","authors":"Yang Cao, Honggang Wang, Yanan Wang, Longhui Li, Yunsheng Qian, Yizheng Lang","doi":"10.1177/08953996241306697","DOIUrl":"10.1177/08953996241306697","url":null,"abstract":"BackgroundThe lobster eye micro pore optics (MPO) plays a pivotal role in X-ray focusing, composed of thousands of hollow square microfibers. The channel error in MPO can profoundly impact its focusing performance. Due to the complex manufacturing process of MPO, there are numerous factors that can contribute to channel errors.ObjectiveThis paper investigates the impact of two key quality indicators of fiber, i.e., diameter precision and ovality, on the focusing performance of flat MPO.MethodsDuring the actual production process of MPO, fibers with varying diameter precision and ovality are utilized, and point-to-point vacuum X-ray focusing equipment is used to assess MPO's focusing performance. Channel error models related to fiber diameter accuracy and ovality are established in the simulation.ResultsExperiments show that both the diameter precision and ovality of fiber influence MPO focusing abilities, with diameter precision primarily affecting the intensity and uniformity of the central point focus and the parallelism of the line foci, while ovality mainly affects the intensity and continuity of the line foci. Numerical simulation results reveal that tilt channel errors significantly affect the X-ray focusing effects.ConclusionsThese findings hold important guiding significance for the preparation process of square fibers and high quality X-ray focusing device.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"350-359"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploiting commercial micro X-ray fluorescence systems for stereoscopic soft X-ray imaging.

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-01 Epub Date: 2025-01-19 DOI: 10.1177/08953996241291356

Ricardo Baettig, Ben Ingram, Ricardo A Cabeza

{"title":"Exploiting commercial micro X-ray fluorescence systems for stereoscopic soft X-ray imaging.","authors":"Ricardo Baettig, Ben Ingram, Ricardo A Cabeza","doi":"10.1177/08953996241291356","DOIUrl":"10.1177/08953996241291356","url":null,"abstract":"BackgroundCommercial micro X-ray fluorescence (μXRF) systems often employ a tilted convergent beam, which can cause a misalignment between X-ray cartography and the corresponding visible images. This misalignment is typically considered a disadvantage, as it hinders the accurate spatial correlation of elemental information. However, this apparent drawback can be exploited to facilitate X-ray stereoscopy.ObjectiveTo demonstrate the use of unmodified commercial μXRF equipment to estimate the 3D configurations of metals and voids within a low-atomic-weight matrix, specifically polymethyl methacrylate, and to explore the implications for enhancing μXRF mapping techniques. This approach could have applications in materials science, archaeology, and other fields requiring non-destructive 3D chemical mapping.MethodsUsing unmodified commercial μXRF equipment, we leveraged both XRF and Compton scattering effects to quantitatively reconstruct the size, position, and depth of embedded tungsten, copper, and silver objects. The study specifically examines how beam divergence affects the acutance of objects located deeper within the sample.ResultsOur findings indicate a depth estimation bias ranging from 4% to 15% for depths between 24 mm, and a size estimation bias below 3.2%. These results validate the methodology and highlight the robustness of our approach under typical operational settings, suggesting that the technique could be applied to a wide range of samples with minimal modifications to existing μXRF systems.ConclusionsThe study confirms that the inclination-induced misalignment in μXRF systems can be harnessed to enhance three-dimensional imaging capabilities. Our work establishes a foundation for advancing current μXRF mapping techniques and interpretation strategies, potentially broadening the applications of μXRF in various scientific and industrial fields.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"285-296"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preconditioned block Kaczmarz methods for linear equations with an application to computed tomography.

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-01 Epub Date: 2025-02-18 DOI: 10.1177/08953996251317421

Duo Liu, Wenli Wang, Gangrong Qu

{"title":"Preconditioned block Kaczmarz methods for linear equations with an application to computed tomography.","authors":"Duo Liu, Wenli Wang, Gangrong Qu","doi":"10.1177/08953996251317421","DOIUrl":"10.1177/08953996251317421","url":null,"abstract":"BackgroundPreconditioned Kaczmarz methods play a pivotal role in image reconstruction. A fundamental theoretical question lies in establishing the convergence conditions for these methods. Practically, devising an efficient block strategy to accelerate the reconstruction process is also critical.ObjectiveThis paper aims to introduce the convergence conditions for the preconditioned Kaczmarz methods and design the block strategy with corresponding preconditioners for these methods in computed tomography (CT).MethodsWe establish a kind of useful convergence conditions for the preconditioned block Kaczmarz methods and prove the dependence of the convergence limit on the initial guess. Tailored for the CT problem, we also propose a new method with a novel block strategy and specific preconditioners, which ensure accelerated convergence.ResultsNumerical experiments with the Shepp-Logan phantom and a real chest CT image demonstrate that our proposed block strategy and preconditioners effectively accelerate the reconstruction process by the preconditioned block Kaczmarz methods while maintaining satisfactory image quality.ConclusionsOur proposed method, which incorporates the designed block strategy and specific preconditioners, has superior performance compared to the traditional Landweber iteration and the block Kaczmarz iteration without preconditioners.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"472-487"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research on meshing method for industrial CT volume data based on iterative smooth signed distance surface reconstruction.

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-01 Epub Date: 2025-01-27 DOI: 10.1177/08953996241306691

ShiBo Jiang, Shuo Xu, YueWen Sun, ZhiFang Wu

{"title":"Research on meshing method for industrial CT volume data based on iterative smooth signed distance surface reconstruction.","authors":"ShiBo Jiang, Shuo Xu, YueWen Sun, ZhiFang Wu","doi":"10.1177/08953996241306691","DOIUrl":"10.1177/08953996241306691","url":null,"abstract":"Industrial Computed Tomography (CT) technology is increasingly applied in fields such as additive manufacturing and non-destructive testing, providing rich three-dimensional information for various fields, which is crucial for internal structure detection, defect detection, and product development. In subsequent processes such as analysis, simulation, and editing, three-dimensional volume data models often need to be converted into mesh models, making effective meshing of volume data essential for expanding the application scenarios and scope of industrial CT. However, the existing Marching Cubes algorithm has issues with low efficiency and poor mesh quality during the volume data meshing process. To overcome these limitations, this study proposes an innovative method for industrial CT volume data meshing based on the Iterative Smooth Signed Surface Distance (iSSD) algorithm. This method first refines the segmented voxel model, accurately extracts boundary voxels, and constructs a high-quality point cloud model. By randomly initializing the normals of the point cloud and iteratively updating the point cloud normals, the mesh is reconstructed using the SSD algorithm after each iteration update, ultimately achieving high-quality, watertight, and smooth mesh model reconstruction, ensuring the accuracy and reliability of the reconstructed mesh. Qualitative and quantitative analyses with other methods have further highlighted the excellent performance of the method proposed in this paper. This study not only improves the efficiency and quality of volume data meshing but also provides a solid foundation for subsequent three-dimensional analysis, simulation, and editing, and has important industrial application prospects and academic value.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"340-349"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A deep learning detection method for pancreatic cystic neoplasm based on Mamba architecture.

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-01 Epub Date: 2025-02-18 DOI: 10.1177/08953996251313719

Junlong Dai, Cong He, Liang Jin, Chengwei Chen, Jie Wu, Yun Bian

{"title":"A deep learning detection method for pancreatic cystic neoplasm based on Mamba architecture.","authors":"Junlong Dai, Cong He, Liang Jin, Chengwei Chen, Jie Wu, Yun Bian","doi":"10.1177/08953996251313719","DOIUrl":"10.1177/08953996251313719","url":null,"abstract":"Objective: Early diagnosis of pancreatic cystic neoplasm (PCN) is crucial for patient survival. This study proposes M-YOLO, a novel model combining Mamba architecture and YOLO, to enhance the detection of pancreatic cystic tumors. The model addresses the technical challenge posed by the tumors' complex morphological features in medical images.Methods: This study develops an innovative deep learning network architecture, M-YOLO (Mamba YOLOv10), which combines the advantages of Mamba and YOLOv10 and aims to improve the accuracy and efficiency of pancreatic cystic neoplasm(PCN) detection. The Mamba architecture, with its superior sequence modeling capabilities, is ideally suited for processing the rich contextual information contained in medical images. At the same time, YOLOv10's fast object detection feature ensures the system's viability for application in clinical practice.Results: M-YOLO has a high sensitivity of 0.98, a specificity of 0.92, a precision of 0.96, an F1 value of 0.97, an accuracy of 0.93, as well as a mean average precision (mAP) of 0.96 at 50% intersection-to-union (IoU) threshold on the dataset provided by Changhai Hospital.Conclusions: M-YOLO(Mamba YOLOv10) enhances the identification performance of PCN by integrating the deep feature extraction capability of Mamba and the fast localization technique of YOLOv10.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"461-471"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orthogonal limited-angle CT reconstruction method based on anisotropic self-guided image filtering. 基于各向异性自引导图像滤波的正交限角 CT 重建方法。

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-01 Epub Date: 2025-01-27 DOI: 10.1177/08953996241300013

Gong Changcheng, Song Qiang

{"title":"Orthogonal limited-angle CT reconstruction method based on anisotropic self-guided image filtering.","authors":"Gong Changcheng, Song Qiang","doi":"10.1177/08953996241300013","DOIUrl":"10.1177/08953996241300013","url":null,"abstract":"Computed tomography (CT) reconstruction from incomplete projection data is significant for reducing radiation dose or scanning time. In this work, we investigate a special sampling strategy, which performs two limited-angle scans. We call it orthogonal limited-angle sampling. The X-ray source trajectory covers two limited-angle ranges, and the angle bisectors of the two angular ranges are orthogonal. This sampling method avoids rapid switching of tube voltage in few-view sampling, and reduces data correlation of projections in limited-angle sampling. It has the potential to become a practical imaging strategy. Then we propose a new reconstruction model based on anisotropic self-guided image filtering (ASGIF) and present an algorithm to solve this model. We construct adaptive weights to guide image reconstruction using the gradient information of reconstructed image itself. Additionally, since the shading artifacts are related to the scanning angular ranges and distributed in two orthogonal directions, anisotropic image filtering is used to preserve image edges. Experiments on a digital phantom and real CT data demonstrate that ASGIF method can effectively suppress shading artifacts and preserve image edges, outperforming other competing methods.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"325-339"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound and advanced imaging techniques in prostate cancer diagnosis: A comparative study of mpMRI, TRUS, and PET/CT.

IF 1.7 3区医学

Journal of X-Ray Science and Technology Pub Date : 2025-03-01 Epub Date: 2025-02-12 DOI: 10.1177/08953996241304988

Ying Dong, Peng Wang, Hua Geng, Yankun Liu, Enguo Wang

{"title":"Ultrasound and advanced imaging techniques in prostate cancer diagnosis: A comparative study of mpMRI, TRUS, and PET/CT.","authors":"Ying Dong, Peng Wang, Hua Geng, Yankun Liu, Enguo Wang","doi":"10.1177/08953996241304988","DOIUrl":"10.1177/08953996241304988","url":null,"abstract":"ObjectiveThis study aims to assess and compare the diagnostic performance of three advanced imaging modalities-multiparametric magnetic resonance imaging (mpMRI), transrectal ultrasound (TRUS), and positron emission tomography/computed tomography (PET/CT)-in detecting prostate cancer in patients with elevated PSA levels and abnormal DRE findings.MethodsA retrospective analysis was conducted on 150 male patients aged 50-75 years with elevated PSA and abnormal DRE. The diagnostic accuracy of each modality was assessed through sensitivity, specificity, and the area under the curve (AUC) to compare performance in detecting clinically significant prostate cancer (Gleason score ≥ 7).ResultsMpMRI demonstrated the highest diagnostic performance, with a sensitivity of 90%, specificity of 85%, and AUC of 0.92, outperforming both TRUS (sensitivity 76%, specificity 78%, AUC 0.77) and PET/CT (sensitivity 82%, specificity 80%, AUC 0.81). MpMRI detected clinically significant tumors in 80% of cases. Although TRUS and PET/CT had similar detection rates for significant tumors, their overall accuracy was lower. Minor adverse events occurred in 5% of patients undergoing TRUS, while no significant complications were associated with mpMRI or PET/CT.ConclusionThese findings suggest that mpMRI is the most reliable imaging modality for early detection of clinically significant prostate cancer. It reduces the need for unnecessary biopsies and optimizes patient management.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"436-447"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0