{"title":"MXene/cellulose nanocrystal-coated cotton fabric electrodes for wearable electronics","authors":"İnal Kaan Duygun, Ayşe Bedeloğlu","doi":"10.1007/s13204-024-03034-1","DOIUrl":"10.1007/s13204-024-03034-1","url":null,"abstract":"<div><p>Increasing mechanical properties without losing electrical properties is of great importance for the development of advanced electronic textile products and their use in different areas. In this study, a cost-effective and facile preparation of MXene/cellulose nanocrystal-coated cotton fabrics by drop-casting was carried out to investigate electrical and mechanical properties of plain woven cotton fabrics. MXene (Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub>) and cellulose nanocrystal dispersions of MXene (5 wt.%, 10 wt.% and 15 wt.% cellulose nanocrystal content) were applied to cotton fabrics, and the coated fabrics were characterized in terms of their morphological and structural properties for their suitability for wearable electronics. The surface resistivity and mechanical properties were also determined to evaluate the effectiveness of coating. Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub>/cellulose nanocrystal dispersions are suitable to obtain a low electrical resistivity (186.4 Ω/sq) in cotton fabrics. The results also showed that increasing cellulose nanocrystal content results in a more stable coating layer on the cotton fabric and a high tensile (63.2 MPa) and elongation at break values are obtained (30.2%) as a result of that.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 3","pages":"575 - 584"},"PeriodicalIF":3.674,"publicationDate":"2024-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140099572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad N. Murshed, Mansour S. Abdul Galil, Samir Osman Mohammed, Mohamed E. El Sayed, Mohyeddine Al‑qubati, Ebkar Abdo Ahmed Saif
{"title":"The study of copper oxide nanoparticles based on the pH varying during propolis-mediated synthesis: structure, optical properties, UV-block ability, and malachite green photodegradation","authors":"Mohammad N. Murshed, Mansour S. Abdul Galil, Samir Osman Mohammed, Mohamed E. El Sayed, Mohyeddine Al‑qubati, Ebkar Abdo Ahmed Saif","doi":"10.1007/s13204-024-03035-0","DOIUrl":"10.1007/s13204-024-03035-0","url":null,"abstract":"<div><p>In third-world countries, the biosynthesis of multi-purpose copper oxide nanoparticles is a crucial solution for pollution, but studies on controlling their properties through internal structure are still limited. This work generated copper oxide nanoparticles (CONPs) using bee propolis as a reducing and capping agent, employing an ecologically benign, simple, inexpensive, and economical technique. The pH of this biosynthesis was varied (6.4, 7.8, 9.2, 10.4, and 11.7). The study computed various structural and optical parameters of biosynthesized CONP samples, revealing nonlinear changes with pH, including unit cell, Cu–O bond length, crystal size, microstrain, energy band gap, Urbach energy, and more. The current research has shown promising results in blocking ultraviolet rays effectively. The blocking parameters were calculated for CONPs samples, and it was found that the pH 8 sample had the best blocking capacity at both regions A and B (90.31 and 91.31%, respectively). The study effectively investigated CONPs’ potential as a catalyst for increasing dye photodegradation. The pH 6.4 sample showed the highest degradation rate (94.15%). The UV-blocking and photodegradation properties of the CONPs samples were explained using the structural and optical parameters.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 3","pages":"585 - 602"},"PeriodicalIF":3.674,"publicationDate":"2024-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s13204-024-03035-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140099766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Asha, M. Chamundeeswari, R. Mary Nancy Flora, N. Padmamalini
{"title":"A new frontier in imaging: natural ore-sourced superparamagnetic magnetite nanoparticles for multi-modal imaging","authors":"A. Asha, M. Chamundeeswari, R. Mary Nancy Flora, N. Padmamalini","doi":"10.1007/s13204-023-02993-1","DOIUrl":"10.1007/s13204-023-02993-1","url":null,"abstract":"<div><p>In the ever-evolving field of medical diagnostics and imaging, the development of efficient and versatile contrast agents remains pivotal. This study presents a pioneering approach to synthesize superparamagnetic magnetite nanoparticles (SM-NPs) derived from natural ore using an environmentally friendly, green chemistry approach. These SM-NPs exhibit exceptional magnetic properties, surpassing all other forms of iron oxide, making them a novel and promising multi-imaging agent for various biomedical applications. The SM-NPs were synthesized with high purity from naturally occurring magnetite, sourced from the Earth's crust. Characterization via X-ray diffraction (XRD) confirmed the cubic spinel ferrites structure of the sample, with an average particle size of 21.24 nm. Fourier-Transform Infrared Spectroscopy (FT-IR) revealed the presence of elemental functional groups, further supporting the material's suitability for biomedical use. Morphological analysis using field emission scanning electron microscopy with energy-dispersive X-ray analysis (FESEM-EDX) unveiled agglomerated spherical particles ranging in size from 60 to 80 nm. The elemental composition analysis via EDX demonstrated predominant iron (Fe) and oxygen (O) elements at concentrations of 75.55% and 20.76%, respectively. The magnetic properties of the SMNPs were assessed using a vibrating sample magnetometer (VSM), revealing a superparamagnetic behavior, as evidenced by the M-H plot. Furthermore, X-ray imaging exhibited a significant signal, even with just 40 mg of the substance, suggesting its potential as a robust contrast agent. Complementary findings from computed tomography (CT) and magnetic resonance imaging (MRI) scans demonstrated substantial absorption capabilities, even at relatively low concentrations of SM-NPs. These remarkable attributes position the green-synthesized SM-NPs as a highly versatile and efficient multi-imaging agent for various biomedical applications. This single nanomaterial can revolutionize disease diagnosis, treatment monitoring, and drug delivery within the biomedical field, offering a greener and more effective approach to medical imaging and diagnostics.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 3","pages":"559 - 573"},"PeriodicalIF":3.674,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140073672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trends in sustainable materials for passive thermal management in 5G enabled portable electronics","authors":"Sriharini Senthilkumar, Brindha Ramasubramanian, Subramanian Sundarrajan, Seeram Ramakrishna","doi":"10.1007/s13204-024-03033-2","DOIUrl":"10.1007/s13204-024-03033-2","url":null,"abstract":"<div><p>The requirement for passive thermal regulation in portable electronic devices enabled by 5G has escalated due to the significant heat produced during the operation of devices, resulting in a detrimental rise in human body temperature and reduced device longevity. This article explores various materials, such as hydrogels, metal–organic frameworks (MOFs), and phase-change materials (PCMs), which utilize natural convection and radiation to dissipate heat from the device, and their potential challenges and solutions for improvement. Hydrogels are not an optimal material due to their lack of cyclic stability and limited water adsorption capability, while MOFs are expensive and PCMs struggle with internal leakage during the solid-to-liquid transition. Thus, insights into novel hybrid materials and their potential for thermal resistance have been discussed. The study considers material marketing and sustainability. To enhance material performance, early-stage inclusion of recyclable, biomass-derived, or environmentally beneficial materials is recommended. Addressing the heat issue in 5G-enabled portable electronics, the article introduces practical passive thermal management materials.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 3","pages":"543 - 557"},"PeriodicalIF":3.674,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140046400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Richard W. van Nieuwenhoven, Alexander M. Bürger, Laura L. E. Mears, Philip Kienzl, Manuel Reithofer, Adelheid Elbe-Bürger, Ille C. Gebeshuber
{"title":"Verifying antibacterial properties of nanopillars on cicada wings","authors":"Richard W. van Nieuwenhoven, Alexander M. Bürger, Laura L. E. Mears, Philip Kienzl, Manuel Reithofer, Adelheid Elbe-Bürger, Ille C. Gebeshuber","doi":"10.1007/s13204-024-03030-5","DOIUrl":"10.1007/s13204-024-03030-5","url":null,"abstract":"<div><p>The antibacterial properties of cicada wings originate from hexagonally arranged pillar-like multi-functional nanostructures with species-dependent heights, which are super-hydrophobic and self-cleaning. In the present study, two cicada species with promising nanopillars were investigated in more detail. Selected methods were used to analyze the wing surfaces, including Atomic Force Microscopy, Scanning Electron Microscopy, and bacterial tests with live/dead staining. Verifying the antibacterial properties posed challenges, such as the bacteria concentration needed to confirm the antibacterial properties. These challenges will also impact the practical implementation of antibacterial nanostructures and support the findings of recent critical publications.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 3","pages":"531 - 541"},"PeriodicalIF":3.674,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s13204-024-03030-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139925959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stacy A. Lynrah, P. Chinnamuthu, Rajshree Rajkumari, Ying Ying Lim, Lanusubo Walling, L. Vigneash
{"title":"Surface functionalization of MnO2 NW embellished with metal nanoparticles for self-cleaning applications","authors":"Stacy A. Lynrah, P. Chinnamuthu, Rajshree Rajkumari, Ying Ying Lim, Lanusubo Walling, L. Vigneash","doi":"10.1007/s13204-024-03032-3","DOIUrl":"10.1007/s13204-024-03032-3","url":null,"abstract":"<div><p>The present study investigates the synthesis of vertically aligned MnO<sub>2</sub> nanowires (NW) decorated with gold (Au) and silver (Ag) nanoparticles (NP) via the glancing angle deposition (GLAD) technique without a need for a catalyst. The cross-sectional field emission scanning electron microscopy (FESEM) image and energy-dispersive X-ray spectroscopy (EDS) confirm the successful adornment of Ag NP and Au NP on the top surface of MnO<sub>2</sub> NW. Elemental mapping has verified the presence of manganese (Mn), oxygen (O), silicon (Si), Ag, and Au within the sample. X-ray diffraction (XRD) patterns reveal the polycrystalline growth of the MnO<sub>2</sub> film with the preferred orientation. AFM reveals that the surface roughness of Au NP/MnO<sub>2</sub> NW is more than Ag NP/MnO<sub>2</sub> NW. The measured water contact angles of Au NP/MnO<sub>2</sub> NW, Ag NP/MnO<sub>2</sub> NW, and MnO<sub>2</sub> NW were 125° and 113°, respectively. Ag NP/MnO<sub>2</sub> NW showed more hydrophilic properties under UV illumination than Au NP/MnO<sub>2</sub> NW owing to the efficient separation of photogenerated electron–hole pairs. Ag NP/MnO<sub>2</sub> NW’s higher photocatalytic activity than Au NP/MnO<sub>2</sub> NW is attributed to the increased light absorption of the Ag NP in the UV region. The overall enhancement after decorating the noble metal NP on MnO<sub>2</sub> NW could open new avenues for self-cleaning applications.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 3","pages":"519 - 529"},"PeriodicalIF":3.674,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139921037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chandra Nath Roy, Susmita Maiti, Tushar Kanti Das, Somashree Kundu, Sudip Karmakar, Aparna Datta, Abhijit Saha
{"title":"Radiation-assisted synthesis of water soluble starch encapsulated copper nanoparticles and its applicability toward photocatalytic reduction of p-nitrophenol","authors":"Chandra Nath Roy, Susmita Maiti, Tushar Kanti Das, Somashree Kundu, Sudip Karmakar, Aparna Datta, Abhijit Saha","doi":"10.1007/s13204-024-03031-4","DOIUrl":"10.1007/s13204-024-03031-4","url":null,"abstract":"<div><p>Copper nanoparticles (CuNPs) have drawn considerable interest because of recent evidences on greater Surface Enhanced Raman Spectroscopic (SERS) signal enhancing capability, high antibacterial activity and strong catalytic property with regard to the long existing popular silver and gold particles. The existing chemical synthesis methods usually require extensive purification to remove unreacted inorganic reducing agents, like sodium borohydride used to convert Cu<sup>2+</sup> ions to Cu<sup>0</sup> and it limits direct use of as-prepared materials in biologic systems. Here, we have endeavored to synthesize starch encapsulated CuNPs through radiation chemical approach which is considered to be one of the cleanest routes and involve <i>in-situ</i> generated hydrated electrons to reduce metal ions directly. Presence of large number of hydroxyl groups within starch molecules facilitates complexation of Cu(II) and thereby stabilizes CuNPs. Transmission electron microscopy (TEM) coupled with selected area electron diffraction (SAED) illustrate that particles synthesized at a typical dose of 83.6 kGy are spherical with size of ca. 8 nm having polycrystalline face-centered cubic phase. The observed blue shift of the absorption maximum suggests formation of smaller sized particles with increase in applied radiation dose keeping other parameters same and this is supported by dynamic light scattering (DLS) data. Further, catalytic efficiency of as-synthesized CuNPs was tested by monitoring sodium borohydride mediated catalytic reduction of <i>para</i>-nitrophenol to <i>para</i>-aminophenol and the apparent rate constant (<i>k</i><sub>app</sub>) was estimated as 3 × 10<sup>–3</sup> s<sup>−1</sup>. Thus, as-synthesized CuNPs appears to be better catalyst than the copper nanoparticles synthesized through conventional method for having <i>k</i><sub>app</sub> of about 1.6 × 10<sup>–3</sup> s<sup>−1</sup>.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 3","pages":"507 - 518"},"PeriodicalIF":3.674,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139758869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peroxidase-mimetic colloidal nanozyme from ozone-oxidized lignocellulosic biomass for biosensing of H2O2 and bacterial contamination in water","authors":"Pravin Savata Gade, Rutuja Murlidhar Sonkar, Dipita Roy, Praveena Bhatt","doi":"10.1007/s13204-024-02995-7","DOIUrl":"10.1007/s13204-024-02995-7","url":null,"abstract":"<div><p>Nanozymes, possessing enzyme-like traits, have gained tremendous attention for their functionality, ease of production, economical synthesis, and stability. Majority of reported nanozymes in literature, for analyte detection are metal-based compounds, transition metal dichalcogenides or single-atom nanozymes. In this study, we report for the first time, a novel peroxidase-mimic, colloidal dendritic nanozyme from lignin-rich agro-industrial residue (coconut husk) by ozonolysis. Synthesized nanozyme exhibited peroxidase-mimic activity in sensing H<sub>2</sub>O<sub>2</sub>, with a wide range of substrates and detection techniques. When 3,3′,5,5′-tetramethylbenzidine (TMB) and 2′,7′–dichlorofluorescin diacetate (DCFDA) were used, the nanozyme demonstrated ultrafast kinetic behaviour with LOD of 43.60 ± 2.41 µM and 1.25 ± 0.31 µM H<sub>2</sub>O<sub>2</sub>, by colorimetric and fluorimetric assays, respectively. The nanozyme-based H<sub>2</sub>O<sub>2</sub> sensing platform, was further utilized for detection of pathogenic bacteria namely <i>Escherichia coli, Listeria monocytogenes, Staphylococcus aureus and Pseudomonas aeruginosa</i>, and for total bacterial load in water. Notably, it demonstrated high sensitivity in the detection of <i>P. aeruginosa</i> with LOD as low as 7 CFU/mL with both fluorimetric and electrochemical methods. Ultrasensitive detection of total bacterial load could also be achieved with 5.5 × 10<sup>2</sup> CFU/mL, 5.5 × 10<sup>1</sup> CFU/mL, and 4.1 × 10<sup>1</sup> CFU/mL by colorimetric, fluorometric, and electrochemical techniques, respectively. Results of the study thus indicate, that the developed nanozyme-based sensing platform had high sensitivity for detection of bacteria as well as versatility with diverse analytical approaches enabling potential practical application for “onsite” monitoring of water quality, especially in rural settings. This biological mimic can also be used in sensor platforms where H<sub>2</sub>O<sub>2</sub> is measured and applied for output signaling.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 3","pages":"491 - 505"},"PeriodicalIF":3.674,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139758930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Munirah D. Albaqami, Sumaira Mnazoor, Mohamed Sheikh, Muhammad Imran Anwar, Abdul Ghafoor Abid
{"title":"Polyoxometalate-mediated growth of O-SnS@Cu2S heteronanosheets for high-performance oxygen and hydrogen evolution reactions","authors":"Munirah D. Albaqami, Sumaira Mnazoor, Mohamed Sheikh, Muhammad Imran Anwar, Abdul Ghafoor Abid","doi":"10.1007/s13204-023-02994-0","DOIUrl":"10.1007/s13204-023-02994-0","url":null,"abstract":"<div><p>To properly exploit undepleted sources of energy through energy conversion devices using water splitting reactions, there is a need for cost-effective, easily accessible, and long-lasting materials that are capable of performing bifunctional activity like hydrogen evolution reaction (HER) and oxygen evolution reaction (OER). In this study, oxygen incorporation into SnS@Cu<sub>2</sub>S (O-SnS@Cu<sub>2</sub>S) heteronanosheets was architecture on Nickel foam utilizing polyoxometalate as bimetal precursors, and then this material exhibited superior activity, requiring only a small overpotential to generate high current densities compared to individual O-SnS and O-Cu<sub>2</sub>S arrays for the electrocatalytic HER activity. The Tafel slopes (26 mV dec<sup>−1</sup>) and electrochemical impedance spectroscopy (EIS) (<i>R</i><sub>ct</sub> = 1.2 Ω), further confirmed the favorable kinetics and conductivity of the O-SnS@Cu<sub>2</sub>S array. When compared to the O-Cu<sub>2</sub>S and O-SnS nanosheet arrays, the bimetal sulphides O-SnS@Cu<sub>2</sub>S array had much lower overpotentials, requiring only 170 mV and 232 mV, respectively, to achieve a current density of 10 mA cm<sup>−2</sup> in an alkaline solution for HER and OER. The O-SnS@Cu<sub>2</sub>S nanosheet array outperformed SnS and Cu<sub>2</sub>S, requiring lower overpotentials to achieve high current densities. The smaller value of Tafel slopes (23 mV dec<sup>−1</sup> for O-SnS@Cu<sub>2</sub>S) indicated improved kinetics, and EIS demonstrated a lower polarization resistance (<i>R</i><sub>ct</sub> = 0.2 Ω) for the O-SnS@Cu<sub>2</sub>S array. Importantly, the O-SnS@Cu<sub>2</sub>S array exhibited remarkable stability in alkaline electrolyte cycling experiments, making it an outstanding material for practical applications in energy conversion devices. This research proposes a feasible technique for the development of efficient and stable bifunctional bimetal-sulfide electrocatalysts with enormous potential for use in renewable energy.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 3","pages":"477 - 489"},"PeriodicalIF":3.674,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139758870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"2D material graphene as a potential antidiabetic and nontoxic compound in Drosophila melanogaster","authors":"Kalpanarani Dash, Deepak kumar Panda, Kushal Yadav, Sonali Meher, Monalisa Mishra","doi":"10.1007/s13204-023-02988-y","DOIUrl":"10.1007/s13204-023-02988-y","url":null,"abstract":"<div><p>This study explains the potential role of non-functionalized graphene produced using flash joule heating technology on <i>Drosophila melanogaster</i>. Several characterizations of the produced graphene were conducted via field emission-scanning electron microscopy, high-resolution transmission electron microscopy, Raman spectroscopy, and X-ray diffraction studies. After being characterized, the graphene powder was orally administered to flies at doses ranging from 0.02 to 0.5%, establishing its non-toxic properties as a prerequisite for potential therapeutic applications. Experiments such as Trypan blue and 4’,6-diamidino-2-phenylindole (DAPI) revealed that graphene causes no harm to the larval gut’s plasma membrane and nucleus. Behavioral assays such as crawling and climbing assays on larvae and adults demonstrated the non-neurotoxic nature of graphene. The high sucrose diet-induced diabetic <i>Drosophila melanogaster</i> model was used to study antidiabetic properties. In contrast, Gram + ve bacteria <i>B. subtilis</i> and Gram − ve <i>P. aeruginosa</i> were used to study the antibacterial properties of graphene. A better metabolic profile was evidenced after graphene treatment, including a 36% decrease in hemolymph-free glucose levels and significantly reduced lipid droplets at the highest concentration. In addition, the highest concentration of graphene treatment resulted in a 57% reduced fluorescent intensity of reactive oxygen species (ROS) produced by diabetic flies. Considering all these evidence, this study concludes that graphene’s non-toxic and antidiabetic properties can be used to mitigate the symptoms associated with Type II diabetes and obesity.</p></div>","PeriodicalId":471,"journal":{"name":"Applied Nanoscience","volume":"14 2","pages":"423 - 439"},"PeriodicalIF":3.674,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139552293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}