Clinical Epidemiology and Global Health最新文献

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Modelling the relationship between extreme temperature metrics and cardiovascular disease burden in India: Insights from a multi-state study on climate change challenges for 2011–2019 印度极端温度指标与心血管疾病负担之间的关系建模:来自2011-2019年气候变化挑战的多州研究的见解
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-06-03 DOI: 10.1016/j.cegh.2025.102084
Soundarya Soundararajan , Bhavani Shankara Bagepally , Jhalak Dhingra , Meghna P. Dinesh , K. Nimithamohan , Rakesh Balachandar
{"title":"Modelling the relationship between extreme temperature metrics and cardiovascular disease burden in India: Insights from a multi-state study on climate change challenges for 2011–2019","authors":"Soundarya Soundararajan ,&nbsp;Bhavani Shankara Bagepally ,&nbsp;Jhalak Dhingra ,&nbsp;Meghna P. Dinesh ,&nbsp;K. Nimithamohan ,&nbsp;Rakesh Balachandar","doi":"10.1016/j.cegh.2025.102084","DOIUrl":"10.1016/j.cegh.2025.102084","url":null,"abstract":"<div><h3>Background</h3><div>Climate change, particularly the rise in global temperatures, has significantly increased the burden of cardiovascular disease (CVD).</div></div><div><h3>Objective</h3><div>The objective of this study is to investigate the CVD-burden attributable to temperature variations within the context of India's diverse climate conditions from 2011 to 2019.</div></div><div><h3>Methods</h3><div>2-m temperature data from the ERA5 dataset is used for estimating temperature metrics—average, median, mode, minimum, maximum, and variations. From the state-level temperature metrics, 2.5th and 97.5th percentiles are identified as extremes. CVD-burden data per 100,000 population, are sourced from the Global Burden of Disease study. The relationship between the temperature predictors and CVD burden is estimated using Poisson panel regression, followed by estimation of incidence rate ratios by exponentiation of coefficients.</div></div><div><h3>Results</h3><div>A unit increase in average temperature increased the CVD-burden by ∼2.5 %. The 97.5th percentile consistently showed strong association with CVD-burden indices. The population attributable fraction for CVD mortality due to elevated average temperatures in India during the study period was estimated as 3.3 %.</div></div><div><h3>Significance</h3><div>These findings reinforce existing research and underscore the impact of temperature variations on the CVD-burden, highlighting the need for public health interventions to mitigate the effects of temperature on cardiovascular health.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102084"},"PeriodicalIF":2.3,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144230721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life and medication adherence of hypertensive patients in Eastern DR Congo: a cross-sectional study 刚果民主共和国东部高血压患者的生活质量和药物依从性:一项横断面研究
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-06-02 DOI: 10.1016/j.cegh.2025.102083
Roland Muyisa , Emile Watumwa , Divine Mataula , Arma Nzanzu , Amani Ngavo , Robert Kanduki , Apollinaire SaaSita , Jacques Wahangire , Jean Paul Mwalitsa , Adélar Kalima , François Mbahweka
{"title":"Quality of life and medication adherence of hypertensive patients in Eastern DR Congo: a cross-sectional study","authors":"Roland Muyisa ,&nbsp;Emile Watumwa ,&nbsp;Divine Mataula ,&nbsp;Arma Nzanzu ,&nbsp;Amani Ngavo ,&nbsp;Robert Kanduki ,&nbsp;Apollinaire SaaSita ,&nbsp;Jacques Wahangire ,&nbsp;Jean Paul Mwalitsa ,&nbsp;Adélar Kalima ,&nbsp;François Mbahweka","doi":"10.1016/j.cegh.2025.102083","DOIUrl":"10.1016/j.cegh.2025.102083","url":null,"abstract":"<div><h3>Introduction</h3><div>Hypertension represents a significant public health issue and stands as one of the most prevalent chronic diseases worldwide, affecting both developed and developing nations. Notably, data regarding hypertension in the Democratic Republic of the Congo (DRC) remains scarce. This study sought to evaluate the effects of adherence to antihypertensive medication on the quality of life among hypertensive patients.</div></div><div><h3>Method</h3><div>This study focused on hypertensive patients aged 18 and older in Katwa, Butembo, and Musienene from July 1 to November 1, 2024, involving 211 patients selected by convenience sampling. Inclusion required at least six months of treatment. Health-Related Quality of Life (HRQoL) was measured using the SF-36 scale, and medication adherence was assessed with the MMAS-8. Data were analyzed through descriptive statistics and linear regression to examine the relationship between adherence and quality of life.</div></div><div><h3>Results</h3><div>The findings indicated a non-adherence rate of 56.40 % among participants. Furthermore, the mean scores across various dimensions of quality of life were observed to be relatively low, particularly in the domain of general health, which registered a score of 36.11 %, indicative of poor quality of life. A significant correlation was identified between high levels of adherence to medication and improvement in specific domains of quality of life, including physical function, social function, physical limitation, and mental health.</div></div><div><h3>Conclusion</h3><div>Hypertensive patients had low treatment adherence, correlating with poor quality-of-life scores, while high adherence was linked to better quality-of-life improvements.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102083"},"PeriodicalIF":2.3,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144196222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Exploring sleep quality, its determinants and the role of workstation in analysis of cognitive and physical parameters in IT professionals” 探讨睡眠质量及其决定因素,以及工作站在IT专业人员认知和身体参数分析中的作用
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-05-31 DOI: 10.1016/j.cegh.2025.102081
Reema Joshi, Kalyani A. Patil
{"title":"“Exploring sleep quality, its determinants and the role of workstation in analysis of cognitive and physical parameters in IT professionals”","authors":"Reema Joshi,&nbsp;Kalyani A. Patil","doi":"10.1016/j.cegh.2025.102081","DOIUrl":"10.1016/j.cegh.2025.102081","url":null,"abstract":"<div><h3>Objective</h3><div>This study explores the impact of personal, lifestyle, and occupational factors on sleep quality among IT professionals and evaluates their influence on cognitive and physical functions.</div></div><div><h3>Methods</h3><div>A cross-sectional analytical design was conducted among 182 IT professionals aged 20–59 years with poor sleep quality (PSQI &gt;5). Reaction time, attention span, and physical performance were evaluated using the Ruler Drop Test, Cancellation Test, and Six-Minute Walk Test, respectively. Workstation ergonomics were assessed objectively through the OSHA-VDT Checklist.</div></div><div><h3>Results</h3><div>Younger age, being married, regular physical activity, vegetarian diet, absence of caffeine, smoking, and alcohol consumption, frequent work breaks, shorter work experience, reduced overtime hours, lower leisure screen time, and compliant workstation ergonomics positively influenced sleep quality (p &lt; 0.05). Poorer sleep quality correlated with reduced physical performance (ρ = 0.312, p = 0.002), attention span (ρ = 0.432, p &lt; 0.0001), and reaction time (ρ = 0.313, p &lt; 0.0001). Workstation compliance was significantly associated with lower prevalence of low vision (χ<sup>2</sup> = 23.08, p &lt; 0.0001).</div></div><div><h3>Conclusion</h3><div>Sleep quality is crucial for optimal cognitive and physical performance in IT professionals. Addressing lifestyle modifications and ergonomic interventions can significantly enhance occupational health, productivity, and well-being.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102081"},"PeriodicalIF":2.3,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term adverse events after COVAXIN vaccination in adolescents (15–18 Years) in Northern India: Frequency, predictors, and reporting behavior 印度北部青少年(15-18岁)接种COVAXIN后的短期不良事件:频率、预测因素和报告行为
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-05-30 DOI: 10.1016/j.cegh.2025.102082
Sujoy Bose , Arpita Bhriguvanshi , Mehul Saxena
{"title":"Short-term adverse events after COVAXIN vaccination in adolescents (15–18 Years) in Northern India: Frequency, predictors, and reporting behavior","authors":"Sujoy Bose ,&nbsp;Arpita Bhriguvanshi ,&nbsp;Mehul Saxena","doi":"10.1016/j.cegh.2025.102082","DOIUrl":"10.1016/j.cegh.2025.102082","url":null,"abstract":"<div><h3>Background</h3><div>India initiated COVID-19 vaccination for adolescents (aged 15–18 years) on January 3, 2022, exclusively using COVAXIN. Adolescent-specific safety data remain limited, and adverse event following immunization (AEFI) reporting is notably low. This study evaluated the frequency, characteristics, and predictors of adolescents' short-term, self-reported AEFI post-COVAXIN vaccination and assessed their awareness and practices regarding official AEFI reporting mechanisms.</div></div><div><h3>Methods</h3><div>A retrospective cohort study was conducted between May and September 2022 among 411 adolescents vaccinated with at least one dose of COVAXIN across schools in urban and rural Lucknow, Northern India. Data on demographics, vaccine doses, AEFI symptoms, onset, duration, management, prior SARS-CoV-2 infection, and awareness and reporting behaviors were collected via a validated questionnaire through face-to-face interviews.</div></div><div><h3>Results</h3><div>65.45 % reported AEFI after the first dose and 56 % after the second. The most common reactions included injection-site pain, fever, and headache, predominantly occurring within 12 h and resolving within three days. Females reported significantly higher AEFI frequency (Adjusted OR = 3.0; 95 %CI:1.23–7.37), and the first dose was associated with greater reactogenicity (Adjusted OR = 1.55; 95 %CI:1.14–2.09). Prior SARS-CoV-2 infections significantly influenced AEFI occurrence. Despite frequent mild, self-limiting symptoms, awareness of official AEFI reporting mechanisms was low (18 %), with only 1.2 % formally reporting their symptoms.</div></div><div><h3>Conclusion</h3><div>COVAXIN vaccination in adolescents demonstrated a favorable short-term safety profile with predominantly mild, transient reactions. However, critically low awareness and negligible formal reporting highlight an urgent need to strengthen vaccine safety monitoring and public education on reporting practices.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102082"},"PeriodicalIF":2.3,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A study to assess willingness and determinants for cadaveric organ donation among family members of deceased individuals autopsied at a tertiary care institute of North India 一项研究评估意愿和决定因素死者的家庭成员尸体器官捐赠在印度北部的三级保健机构的尸体解剖
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-05-30 DOI: 10.1016/j.cegh.2025.102078
Rajesh Kumar , Deepak Prakash , MD. Abu Bashar , Ajay Kumar Patel , Abhaykumar Binodkumar Dheeraj , Nishat Ahmed Sheikh
{"title":"A study to assess willingness and determinants for cadaveric organ donation among family members of deceased individuals autopsied at a tertiary care institute of North India","authors":"Rajesh Kumar ,&nbsp;Deepak Prakash ,&nbsp;MD. Abu Bashar ,&nbsp;Ajay Kumar Patel ,&nbsp;Abhaykumar Binodkumar Dheeraj ,&nbsp;Nishat Ahmed Sheikh","doi":"10.1016/j.cegh.2025.102078","DOIUrl":"10.1016/j.cegh.2025.102078","url":null,"abstract":"<div><h3>Objective</h3><div>The study aimed to assess the willingness for organ donation among the family members of deceased individuals whose bodies were brought for postmortem examination and the sociodemographic factors associated with it at a tertiary care institute in North India.</div></div><div><h3>Methods</h3><div>A prospective observational study was conducted at the Department of Forensic Medicine &amp; Toxicology at the All India Institute of Medical Sciences, New Delhi. All medico-legal autopsy cases eligible for organ donation were included in the study, while cases with known contraindications to organ donation were excluded. The family member/immediate next of kin were approached for the consent for organ donation.</div></div><div><h3>Results</h3><div>A total of 811 medico-legal autopsies were performed during the study period. Among these, the family members of 244 eligible cases could be approached for cadaveric organ donation, of which only 62 (25.4 %) provided the consent. The factors found to be significantly associated with providing consent for organ donation were prior knowledge about organ donation, religion of the participant, education status of the participant, pledge to donation by the deceased individual and counselling provided by a doctor. The commonest reasons given by the participants for refusal of organ donations were disfigurement of the deceased's body (19.2 %) and the religious beliefs (15.4 %)</div></div><div><h3>Conclusion</h3><div>Unnatural deaths cases coming for medico-legal autopsy form a major potential pool of organ donors. However, a potentially large donor pool of these death cases is compromised by the lost opportunity cases which could not be approached timely for organ donation and the low acceptance rate for donation.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102078"},"PeriodicalIF":2.3,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traditional remedies from Aceh for diabetes mellitus treatment: Patterns of use in rural-urban areas in Aceh 亚齐治疗糖尿病的传统疗法:亚齐城乡地区的使用模式
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-05-27 DOI: 10.1016/j.cegh.2025.102079
Fauzul Husna , Marisa Marisa , Suryawati Suryawati , Frans D. Suyatna , Husnah Husnah , Rani Wardani Hakim , Muhammad Imam Aulia , Efan Andriansyah Dasopang
{"title":"Traditional remedies from Aceh for diabetes mellitus treatment: Patterns of use in rural-urban areas in Aceh","authors":"Fauzul Husna ,&nbsp;Marisa Marisa ,&nbsp;Suryawati Suryawati ,&nbsp;Frans D. Suyatna ,&nbsp;Husnah Husnah ,&nbsp;Rani Wardani Hakim ,&nbsp;Muhammad Imam Aulia ,&nbsp;Efan Andriansyah Dasopang","doi":"10.1016/j.cegh.2025.102079","DOIUrl":"10.1016/j.cegh.2025.102079","url":null,"abstract":"<div><h3>Background</h3><div>Diabetes Mellitus (DM) is a metabolic disease characterized by hyperglycemia due to a decrease in the function of the insulin hormone in lowering blood sugar levels or insulin resistance. In Aceh, Indonesia, traditional medicine remains integral to the healthcare practices of its communities, including for managing DM.</div></div><div><h3>Objective</h3><div>This research aims to analyze the prevalence of medicinal plant use, identify the underlying reasons for their utilization, and determine the most commonly used traditional plants in managing DM in the Acehnese community in urban and rural areas. <strong>Materials and Methods</strong>: A cross-sectional study involving 164 DM patients was conducted in two community health centers in Banda Aceh using a questionnaire-assisted face-to-face interview.</div></div><div><h3>Results</h3><div>The findings revealed that 47 % of respondents used medicinal plants, with women (p = 0.007, OR = 2.85) and patients with comorbidities (p = 0.002, OR = 2.81) considerably more likely to take herbal medicines. 85.71 % of respondent expressed satisfaction with herbal therapies, and the primary reasons for use were trust in their effectiveness (67.53 %) and accessibility (23.37 %).</div></div><div><h3>Conclusion</h3><div>The most commonly used plant materials are <em>Moringa oleifera</em> (19.48 %), <em>Syzygium polyanthum</em> (18.18 %), and <em>Annona muricata</em> (12.98 %). However, 37.66 % of participants did not consult healthcare professionals about their herbal use. Traditional medicine plays a crucial role in DM management among Acehnese communities, driven by cultural norms.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102079"},"PeriodicalIF":2.3,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of RDT kit for screening anaemia among women of reproductive age at the field level in comparison with the gold standard in rural areas of coastal Karnataka, India 与印度卡纳塔克邦沿海农村地区的黄金标准相比,实地验证用于筛查育龄妇女贫血的RDT试剂盒
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-05-24 DOI: 10.1016/j.cegh.2025.102077
K. Jayaprakash Shetty , S. Nanjesh Kumar , K. Shrisharath
{"title":"Validation of RDT kit for screening anaemia among women of reproductive age at the field level in comparison with the gold standard in rural areas of coastal Karnataka, India","authors":"K. Jayaprakash Shetty ,&nbsp;S. Nanjesh Kumar ,&nbsp;K. Shrisharath","doi":"10.1016/j.cegh.2025.102077","DOIUrl":"10.1016/j.cegh.2025.102077","url":null,"abstract":"<div><h3>Background</h3><div>Anaemia in women of reproductive age is still a problem for public health worldwide. As per NFHS-5 data anaemia among reproductive age group is about 57 %. Anaemia is indicative of poor nutrition and health. The most common type of anaemia is due to nutritional factors.</div></div><div><h3>Objective</h3><div>To validate the Rapid Diagnostic Test (RDT) kit used for screening anaemia among women of child bearing age group at the field level in comparing with gold standard test.</div></div><div><h3>Methodology</h3><div>A community-based cross-sectional study done among women in reproductive age group using RDT kit in the rural area of Coastal Karnataka. Villages were selected from Udupi and Dakshina Kannada Districts of Coastal Karnataka.</div></div><div><h3>Results</h3><div>A total of 1443 subjects consented and were screened for anaemia using RDT kit in comparison with gold standard method. 43 % individuals were classified as anaemic by both methods. Sensitivity = 78.90 %, Specificity = 94.04 %, Positive predictive value (PPV) = 90.91 %. Negative predictive value (NPV) = 85.51 %, The accuracy of RDT kit at 95 % CI was 87.53 % (85.71 %, 89.19 %). With a specificity of 94.04 % and an accuracy of 87.53 %.</div></div><div><h3>Conclusion</h3><div>The use of RDT kit at the field level can be used as a tool for screening and monitoring of anaemia at the field level. The RDT kit can be used in areas where access to healthcare facilities is limited and at the field level for haemoglobin estimation by grassroots healthcare workers. The RDT kit results are reliable.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102077"},"PeriodicalIF":2.3,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinicoradiological profile of children presenting with global developmental delay and microcephaly 儿童整体发育迟缓和小头畸形的临床放射学分析
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-05-24 DOI: 10.1016/j.cegh.2025.102076
ShreyasT.S. Phayde, Suneel C. Mundkur, Rochelle A. Pereira, Leslie E. Lewis, Shrikiran A. Hebbar, Ramesh Bhat Y, Pushpa Kini, Karen J. Moras
{"title":"Clinicoradiological profile of children presenting with global developmental delay and microcephaly","authors":"ShreyasT.S. Phayde,&nbsp;Suneel C. Mundkur,&nbsp;Rochelle A. Pereira,&nbsp;Leslie E. Lewis,&nbsp;Shrikiran A. Hebbar,&nbsp;Ramesh Bhat Y,&nbsp;Pushpa Kini,&nbsp;Karen J. Moras","doi":"10.1016/j.cegh.2025.102076","DOIUrl":"10.1016/j.cegh.2025.102076","url":null,"abstract":"<div><h3>Objective</h3><div>To study the clinical and radiological profile of children with Global developmental delay and microcephaly and correlate the clinical findings with structural brain lesions identified through neuroimaging.</div></div><div><h3>Methods</h3><div>This single-centre study, conducted from April 1, 2017 to March 31, 2022, included 247 children with global developmental delay and microcephaly. Data was collected using a pre-designed proforma, documenting presenting complaints, birth and developmental history, growth patterns, physical and neurological examination results, associated co-morbidities with neuroimaging findings.</div></div><div><h3>Results</h3><div>Among the 247 children, 197 (79.8 %) were under 5 years, and 50 (20.2 %) were over 5 years, with a male-to-female ratio of 1.5:1 and a median age of 3.3 years(1.1, 5). Perinatal asphyxia was noted in 83 children (33.6 %). A total of 145 children under 5 years (58.7 %) were malnourished, and 14 children over 5 years (28 %) were underweight. Seizures were the most common co-morbidity, affecting 154 children (62.3 %), visual abnormalities were detected in 118 children, (47.8 %) and hearing abnormalities in approximately one-sixth (15 %). Abnormal MRI was noted in 187 (75.7 %), with white matter lesions being the most common, observed in 155 children (62.7 %). Children born with birth asphyxia displayed significant MRI abnormalities in the ventricles, corpus callosum, and gray and white matter (p &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>This study outlines the complex clinicoradiological profile of children with GDD and microcephaly, highlighting common MRI abnormalities such as white matter and corpus callosum lesions. Seizures and perinatal factors significantly affect MRI findings, underscoring the need for comprehensive evaluation and management strategies.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102076"},"PeriodicalIF":2.3,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catastrophic costs of Tuberculosis in patients registered under the National Tuberculosis Elimination Programme in South-East Delhi, India 在印度德里东南部国家消除结核病规划下登记的患者的结核病灾难性费用
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-05-22 DOI: 10.1016/j.cegh.2025.102075
Tazean Zahoor Malik , Faheem Ahmed , Sushovan Roy , Rashmi Agarwalla , Rambha Pathak
{"title":"Catastrophic costs of Tuberculosis in patients registered under the National Tuberculosis Elimination Programme in South-East Delhi, India","authors":"Tazean Zahoor Malik ,&nbsp;Faheem Ahmed ,&nbsp;Sushovan Roy ,&nbsp;Rashmi Agarwalla ,&nbsp;Rambha Pathak","doi":"10.1016/j.cegh.2025.102075","DOIUrl":"10.1016/j.cegh.2025.102075","url":null,"abstract":"<div><h3>Background</h3><div>Tuberculosis (TB) is one of the leading causes of death from an infectious agent. Tuberculosis patients often fall into a “poverty medical trap” due to the cost of treatment. The present study aimed to estimate the economic burden of TB in registered patients undergoing treatment under the national programme.</div></div><div><h3>Methodology</h3><div>The study was a mixed-method study conducted in various DOTS centres of South-East Delhi. Quantitative data collection was done using a validated questionnaire, while focus group discussions helped triangulate data generated by quantitative methods. Data on socio-demographics, disease-specific characteristics, and costs were gathered. Descriptive statistics delineated sample characteristics. Univariate analysis helped understand the factors influencing the catastrophic costs.</div></div><div><h3>Results</h3><div>A total of 439 Tuberculosis patients in the Intensive phase of treatment were approached, out of which 416 consented to participate in the study. The mean (±S.D) total costs were Rs. 5923 ± 1243.2 while the mean direct and indirect costs were Rs. 4553.6 ± 623.2 and Rs. 2475.4 ± 540.1, respectively. The total costs were significantly associated (p &lt; 0.05) with the type of TB in the patient (more in EPTB patients), the type of health facility first visited (private more than government) and the employment status (highest cost in those who had employment of some kind). The catastrophic costs were experienced by 24.27 % of households.</div></div><div><h3>Conclusion</h3><div>Despite the free diagnosis and treatment of tuberculosis in the country, patients still experienced direct and indirect costs in the present study. More robust mechanisms and strategies are needed to reach the WHO End TB strategy target of ‘Zero Catastrophic Costs’.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102075"},"PeriodicalIF":2.3,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal mortality at Souissi Maternity Hospital in Rabat, 2018–2021 2018-2021年拉巴特Souissi妇产医院的孕产妇死亡率
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-05-21 DOI: 10.1016/j.cegh.2025.102064
Fatima Elhassouni , Rim Laaboudi , Ismail Belhaouz , Rachid Razine , Majdouline Obtel , Yahaya Maijimaa Tourey , Sabah Amrani , Zaki Hanchi , Mounia El Yousfi , Nada Bennani Mechita
{"title":"Maternal mortality at Souissi Maternity Hospital in Rabat, 2018–2021","authors":"Fatima Elhassouni ,&nbsp;Rim Laaboudi ,&nbsp;Ismail Belhaouz ,&nbsp;Rachid Razine ,&nbsp;Majdouline Obtel ,&nbsp;Yahaya Maijimaa Tourey ,&nbsp;Sabah Amrani ,&nbsp;Zaki Hanchi ,&nbsp;Mounia El Yousfi ,&nbsp;Nada Bennani Mechita","doi":"10.1016/j.cegh.2025.102064","DOIUrl":"10.1016/j.cegh.2025.102064","url":null,"abstract":"<div><h3>Backgroung</h3><div>Maternal deaths are a major public health issue and serve as a crucial indicator for assessing a country's level of health development. The aim of this study is to describe the epidemiological characteristics of maternal deaths occurring at the Souissi Maternity Hospital in Rabat between 2018 and 2021.</div></div><div><h3>Methods</h3><div>This is a retrospective descriptive study. All cases of maternal death occurring at the Souissi Maternity Hospital in Rabat between January 2018 and December 2021 were included in this study. Data were collected from medical records. We divided the study into two phases (2018–2019 and 2020–2021), to be able to compare the mortality rate before and after COVID-19. Causes of death were also compared between these two phases using Khi<sup>2</sup> test or fisher's exact test.</div></div><div><h3>Results</h3><div>During the entire study period (2018–2021), the Maternal Mortality Rate was 156.03 deaths per 100,000 live births. This rate rose from 88.84 to 261.49 per 100,000 live births between the two study phases (p &lt; 0.001). Sixty-eight cases were linked to a direct cause (73.9 %). Preeclampsia and eclampsia was the leading cause of maternal mortality by direct cause (30.9 %), and hemorrhage was the second leading cause (25.0 %).</div></div><div><h3>Conclusion</h3><div>The study identified preeclampsia and postpartum hemorrhage as the leading causes of death, both of which are highly preventable. Recognizing risk factors through a case-control study is essential, and targeted interventions could help reduce maternal mortality.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102064"},"PeriodicalIF":2.3,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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