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Gastric cancer epidemiology in the Adi tribe of Arunachal Pradesh, India: An ethnic-specific risk factors study
IF 1.9
Clinical Epidemiology and Global Health Pub Date : 2026-07-01 Epub Date: 2026-06-15 DOI: 10.1016/j.cegh.2026.102408
Montak Mongku, Kaling Jerang, Bomni Tayeng, Donyi Ratan, Jumba Gibi, Tomeru Rina, Lalengkimi Ralte, Nachimuthu Senthil Kumar, Kiran Ramesh Kharat
{"title":"Gastric cancer epidemiology in the Adi tribe of Arunachal Pradesh, India: An ethnic-specific risk factors study","authors":"Montak Mongku,&nbsp;Kaling Jerang,&nbsp;Bomni Tayeng,&nbsp;Donyi Ratan,&nbsp;Jumba Gibi,&nbsp;Tomeru Rina,&nbsp;Lalengkimi Ralte,&nbsp;Nachimuthu Senthil Kumar,&nbsp;Kiran Ramesh Kharat","doi":"10.1016/j.cegh.2026.102408","DOIUrl":"10.1016/j.cegh.2026.102408","url":null,"abstract":"<div><h3>Problem considered</h3><div>Gastric cancer exhibits exceptional ethnic disparities, with tribal populations in Arunachal Pradesh experiencing incidence rates rivalling those of East Asian populations; however, systematic epidemiological investigations among these indigenous populations remain unexplored.</div></div><div><h3>Methods</h3><div>This population-based case-control study recruited 121 gastric cancer patients and 373 age- and BMI-matched healthy controls from the Adi tribe. Chi-square tests and binary logistic regression were used to calculate odds ratios with 95% confidence intervals.</div></div><div><h3>Results</h3><div>Multiple ethnicity-specific dietary and lifestyle risk factors were identified. Imported fish consumption conferred the highest risk (AOR = 8.109; 95% CI: 1.746-37.656), followed by smoked meat and fish (odds ratios and 95% confidence intervals were computed using chi-square testing and binary logistic regression, AOR = 7.525; 95% CI: 2.025-27.970), smokeless tobacco use (AOR = 7.445; 95% CI: 1.607-34.498), traditional fermented alcohol (AOR = 5.851; 95% CI: 1.286-26.624), and excess salt (AOR = 3.091; 95% CI: 1.044-9.150). Three protective factors substantially reduced odds: fruits (AOR = 0.012; 95% CI: 0.003-0.039), water consumption &gt;1 L/day (AOR = 0.096; 95% CI: 0.034-0.272), and local fish (AOR = 0.099; 95% CI: 0.014-0.696).</div></div><div><h3>Conclusion</h3><div>This first systematic investigation of gastric cancer among the Adi tribe identified local alcohol, smokeless tobacco, imported fish, excessive salt, and smoked food (meat and fish) as significant risk factors for gastric cancer. In contrast, regular fruit intake and adequate water consumption provided strong protective effects. Culturally tailored interventions to address risks, promote protective factors, and improve healthcare access and adherence may prove beneficial.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"40 ","pages":"Article 102408"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatial and logistic regression analysis of factors influencing antenatal care in Uttar Pradesh, India 印度北方邦产前保健影响因素的空间和逻辑回归分析
IF 1.9
Clinical Epidemiology and Global Health Pub Date : 2026-07-01 Epub Date: 2026-06-23 DOI: 10.1016/j.cegh.2026.102409
Sumedha Sharma, Dharma Raj, Pinky Pandey, Shalwee, Niraj Kumar Singh
{"title":"Spatial and logistic regression analysis of factors influencing antenatal care in Uttar Pradesh, India","authors":"Sumedha Sharma,&nbsp;Dharma Raj,&nbsp;Pinky Pandey,&nbsp;Shalwee,&nbsp;Niraj Kumar Singh","doi":"10.1016/j.cegh.2026.102409","DOIUrl":"10.1016/j.cegh.2026.102409","url":null,"abstract":"<div><h3>Objective</h3><div>This study examines the determinants of Antenatal care uptake, focusing on socioeconomic, demographic, and geographic disparities.</div></div><div><h3>Study design</h3><div>The study was conducted using data from the National Family Health Survey (NFHS-5).</div></div><div><h3>Methods</h3><div>Logistic regression was employed to identify factors influencing ANC utilization, while spatial analysis using scan statistics was performed to detect geographic disparities.</div></div><div><h3>Results</h3><div>Logistic regression analysis revealed that birth order, maternal education, and household wealth significantly impacted ANC utilization. Women with secondary or higher education and those from wealthier households were more likely to receive complete ANC. Regional disparities were observed, with Bundelkhand demonstrating higher ANC uptake compared to the Western and Central regions. Spatial clustering analysis identified districts such as Kanpur Dehat, Auraiya, and Siddharthnagar as hotspots for less than four ANC visits, indicating persistent inequities.</div></div><div><h3>Conclusion</h3><div>Socioeconomic and geographic factors influence ANC access, necessitating targeted interventions, particularly in rural and underserved areas. Strengthening healthcare infrastructure, improving educational outreach, and addressing economic barriers can enhance maternal healthcare access in Uttar Pradesh.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"40 ","pages":"Article 102409"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delivering nurturing care for small and sick newborns in facility-based settings: A scoping review of implementation approaches 在以设施为基础的环境中为小新生儿和患病新生儿提供养育护理:对实施方法的范围审查
IF 1.9
Clinical Epidemiology and Global Health Pub Date : 2026-07-01 Epub Date: 2026-06-24 DOI: 10.1016/j.cegh.2026.102413
Arti Maria, Manish Pal, Manish Singh Chundawat, Aarushi Mavi, Hamza Salah, Divita Sharma, Ritika Mukherjee, Gwinyai Masukume, Roy K. Philip, Archisman Mohapatra
{"title":"Delivering nurturing care for small and sick newborns in facility-based settings: A scoping review of implementation approaches","authors":"Arti Maria,&nbsp;Manish Pal,&nbsp;Manish Singh Chundawat,&nbsp;Aarushi Mavi,&nbsp;Hamza Salah,&nbsp;Divita Sharma,&nbsp;Ritika Mukherjee,&nbsp;Gwinyai Masukume,&nbsp;Roy K. Philip,&nbsp;Archisman Mohapatra","doi":"10.1016/j.cegh.2026.102413","DOIUrl":"10.1016/j.cegh.2026.102413","url":null,"abstract":"<div><h3>Background</h3><div>Early-life nurturing care (NC) interventions are crucial to shape developmental trajectories of small and sick newborns, facing adverse experiences in neonatal care units (NCUs). However, NC implementation remains inconsistent globally. This review catalogued interventions aligned with Nurturing Care Framework (NCF), described implementation strategies, and explored barriers and enablers.</div></div><div><h3>Methods</h3><div>Following Joanna Briggs Institute guidance and PRISMA-ScR, we searched four databases (PubMed, Scopus, CINAHL, and Campbell Collaboration) for English-language sources (January 2015 to April 2025). Two reviewers independently screened, selected, and charted data aligned with NCF domains, resolving disagreements with the third reviewer. Findings were synthesized using descriptive mapping and realist-informed context-mechanism-outcome configurations.</div></div><div><h3>Results</h3><div>Of 1125 articles screened, 13 studies were selected (seven from low- and middle-income countries; 10 randomized controlled trials, three observational; five implementation research, one quality improvement). NCF components frequently addressed were safety and security (n = 12), responsive caregiving (n = 9), adequate nutrition (n = 8), and opportunities for early learning (n = 8); good health was least addressed (n = 1). Interventions like non-pharmacological pain management, environmental modifications, caregiver-led practices and digital training, reduced neonatal stress, improved feeding readiness, and shortened hospital stays. Enablers included leadership commitment, trained staff, and family engagement. Barriers included environmental stressors, fragmented protocols, and staff turnover. Implementation and sustainability were inconsistently reported.</div></div><div><h3>Conclusion</h3><div>Evidence on facility-based NC for small and sick newborns is growing but remains fragmented, with limited reporting on strategies, fidelity, and sustainability. Future studies should use implementation science frameworks and prioritize workforce, infrastructure, and policy support to embed NC within NCU protocols.</div></div><div><h3>Registration</h3><div>Open Science Framework (OSF) protocol: <span><span>https://osf.io/aqpyw</span><svg><path></path></svg></span></div></div><div><h3>Reporting</h3><div>PRISMA-ScR checklist and flow diagram are provided in the supplementary materials.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"40 ","pages":"Article 102413"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Micronutrient and haemato-biochemical predictors of gestational diabetes mellitus (GDM): A case-control study in Middle and Northern Ghana 微量营养素和血液生化预测妊娠糖尿病(GDM):在加纳中部和北部的病例对照研究
IF 1.9
Clinical Epidemiology and Global Health Pub Date : 2026-07-01 Epub Date: 2026-06-13 DOI: 10.1016/j.cegh.2026.102399
Daniel Ataanya Abera, Christopher Larbie, Mohamed Mutocheluh, Julius Dongsogo, Jacob Amonoo-Neizer, Mina Ofosu, James Abugri
{"title":"Micronutrient and haemato-biochemical predictors of gestational diabetes mellitus (GDM): A case-control study in Middle and Northern Ghana","authors":"Daniel Ataanya Abera,&nbsp;Christopher Larbie,&nbsp;Mohamed Mutocheluh,&nbsp;Julius Dongsogo,&nbsp;Jacob Amonoo-Neizer,&nbsp;Mina Ofosu,&nbsp;James Abugri","doi":"10.1016/j.cegh.2026.102399","DOIUrl":"10.1016/j.cegh.2026.102399","url":null,"abstract":"<div><h3>Background</h3><div>Gestational diabetes mellitus (GDM), commonly diagnosed through an oral glucose tolerance test (OGTT), is a widespread pregnancy complication. This study addresses the gap in research on micronutrients and haemato-biochemical factors in GDM in Ghana, exploring these parameters as predictors among pregnant women.</div></div><div><h3>Methods</h3><div>In this prospective case-control study, 180 pregnant women, comprising 130 with gestational diabetes and 50 without (controls), were investigated at Tamale and Komfo Anokye Teaching Hospitals. Socio-demographics, anthropometrics, and nutrition data were gathered through a questionnaire; blood samples were analysed for hemato-biochemical parameters and micronutrients. Statistical analysis employed SPSS version 26.0 and R with P &lt; 0.05.</div></div><div><h3>Results</h3><div>This study found ‘dawadawa’ intake (aOR = 7.41, 95% CI: (2.40-22.89); p = 0.001), Zinc intake (aOR = 3.57, 95% CI: (1.95-6.53); p &lt; 0.0001) and increasing platelet count (aOR = 1.12, 95%, p = 0.009) independently predict GDM. However, late gestational age of 36-41 weeks, intake of only iron (aOR = 0.02, 95% CI: (0.00-0.15); p &lt; 0.0001) and liver intake (aOR = 0.23, 95% CI: (0.09-0.60); p = 0.001) independently decreased the chances of GDM by 80%, 98% and 77% respectively. In addition, chromium supplementation independently decreased GDM. A significant positive weak correlation was observed between red blood cell count (r = 0.196, p = 0.025) and fasting blood sugar.</div></div><div><h3>Conclusion</h3><div>The current findings emphasize the need for effective strategies with a call for midwives to provide education and advocate dietary and behavioural adjustments for pregnant women.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"40 ","pages":"Article 102399"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of midwife-led continuous childbirth support on labor pain and satisfaction of primigravida women in northwest Ethiopia: Implementation evaluation 助产士主导的持续分娩支持对埃塞俄比亚西北部初产妇分娩疼痛和满意度的影响:实施评价
IF 1.9
Clinical Epidemiology and Global Health Pub Date : 2026-07-01 Epub Date: 2026-07-04 DOI: 10.1016/j.cegh.2026.102415
Mengstu Melkamu Asaye, Getie Mihret Aragaw, Kihinetu Gelaye Wudineh, Eden Bishaw Taye, Kerstin Erlandsson
{"title":"Effect of midwife-led continuous childbirth support on labor pain and satisfaction of primigravida women in northwest Ethiopia: Implementation evaluation","authors":"Mengstu Melkamu Asaye,&nbsp;Getie Mihret Aragaw,&nbsp;Kihinetu Gelaye Wudineh,&nbsp;Eden Bishaw Taye,&nbsp;Kerstin Erlandsson","doi":"10.1016/j.cegh.2026.102415","DOIUrl":"10.1016/j.cegh.2026.102415","url":null,"abstract":"<div><h3>Background</h3><div>Primigravida women experience increased labor pain and emotional distress. Midwife-led continues labor support offers emotional benefits and reduces maternal and newborn complications; however, its effects on primigravidas’ labor pain, satisfaction, and newborn admissions has not been studied in Ethiopia.</div></div><div><h3>Objective</h3><div>This study aimed to evaluate the effect of midwife-led continuous labor support on primigravida women's labor pain, satisfaction, and newborn admission rates.</div></div><div><h3>Methods</h3><div>A quasi-experimental study compared midwife-led continuous labor support with routine care among 419 primigravida women at four Ethiopian hospitals (two intervention, two control). Data were collected from July to December 2024 through interviews and records. Senior midwives and the principal investigator trained all midwives at the intervention sites, as well as two additional midwives for overload periods. Support averaged 90 min per woman. Fisher's Exact test e assed changes (P &lt; 0.05).</div></div><div><h3>Results</h3><div>Midwife-led continuous labour support increased maternal satisfaction among primigravida women from 147 (71.4%) in the control group to 167 (78.4%) in the intervention group, a net increase of 7% (P &lt; 0.001). It reduced pain from 136 (66%) to 98 (46%), a net decrease of 20% (P &lt; 0.037). Neonatal intensive care unit admissions decreased from 23 (11.2%) to 12 (5.6%), a net reduction of 6.6% (P &lt; 0.004). There was no effect on newborn death rates.</div></div><div><h3>Conclusions</h3><div>Midwife-led support effectively reduced pain, increased satisfaction, and decreased NICU admission for primigravida women in Ethiopia through continues psychological and physical support, improving maternal and newborn wellbeing. Implementing this approach facility-wide and evaluate sustainability in routine care is necessary.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"40 ","pages":"Article 102415"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of antimicrobial usage & associated factors among aquaculture farmers in a district of eastern India 印度东部一个地区水产养殖户抗菌药物使用及相关因素的评估
IF 1.9
Clinical Epidemiology and Global Health Pub Date : 2026-07-01 Epub Date: 2026-06-17 DOI: 10.1016/j.cegh.2026.102410
Swati Behera, Navya Vyas, Rinila Das, R. Abinayasundari
{"title":"Assessment of antimicrobial usage & associated factors among aquaculture farmers in a district of eastern India","authors":"Swati Behera,&nbsp;Navya Vyas,&nbsp;Rinila Das,&nbsp;R. Abinayasundari","doi":"10.1016/j.cegh.2026.102410","DOIUrl":"10.1016/j.cegh.2026.102410","url":null,"abstract":"<div><h3>Problem considered</h3><div>Aquaculture, the breeding of aquatic organisms, is expanding rapidly and can improve food security. However, the excessive antimicrobial use in aquaculture contributes to antimicrobial resistance, posing environmental threats. This study aimed to assess antimicrobial usage in aquaculture and to examine factors influencing their usage.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted from January to June 2024 among 310 aquaculture farmers in a district of an eastern state of India. Participants with at least one year of farming experience were selected using probability proportionate to size (PPS) sampling. Data were collected using a semi-structured, expert-validated questionnaire, covering socio-demographic characteristics, farm details, antimicrobials knowledge, usage patterns, and awareness of Antimicrobial Resistance. Data were analysed using Jamovi (version 2.3.28). Descriptive statistics were computed, and associated factors were analysed using chi-square tests and multivariate logistic regression.</div></div><div><h3>Results</h3><div>Majority (52.9%) of the farmers were not registered under the Pradhan Mantri Matsya Sampada Yojana (PMMSY). All practiced freshwater aquaculture, with whiteleg shrimp being the predominant species (79.35%). Although 98.7% farmers had heard of antimicrobials, appropriate knowledge of rational use was limited. Antimicrobials were commonly used without prescriptions, with incomplete treatment courses, and poorly followed recommended dosages. Record-keeping was uncommon, and 98.1% were unaware of AMR.</div></div><div><h3>Conclusion</h3><div>The study highlights widespread unregulated antimicrobial use driven by inadequate knowledge and limited professional guidance. These findings emphasize the need for targeted awareness programs, regulatory enforcement, and capacity-building initiatives to promote rational antimicrobial use and support sustainable aquaculture in alignment with the Sustainable Development Goals.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"40 ","pages":"Article 102410"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The silent emergency: acute malnutrition among Somali children demands urgent global attention 无声的紧急情况:索马里儿童的严重营养不良需要全球紧急关注
IF 1.9
Clinical Epidemiology and Global Health Pub Date : 2026-07-01 Epub Date: 2026-06-22 DOI: 10.1016/j.cegh.2026.102411
Fatima Abdijabbar Ibrahim, Nasro Salad Ahmed, Fardowso Hassan Maxamud, Anisa Hassan Elmi, Yakub Burhan Abdullahi
{"title":"The silent emergency: acute malnutrition among Somali children demands urgent global attention","authors":"Fatima Abdijabbar Ibrahim,&nbsp;Nasro Salad Ahmed,&nbsp;Fardowso Hassan Maxamud,&nbsp;Anisa Hassan Elmi,&nbsp;Yakub Burhan Abdullahi","doi":"10.1016/j.cegh.2026.102411","DOIUrl":"10.1016/j.cegh.2026.102411","url":null,"abstract":"","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"40 ","pages":"Article 102411"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The hidden burden of undiagnosed diabetic kidney disease in primary care: Lessons from a rural Indian health system 初级保健中未确诊的糖尿病肾病的隐性负担:来自印度农村卫生系统的经验教训
IF 1.7
Clinical Epidemiology and Global Health Pub Date : 2026-05-01 Epub Date: 2026-05-06 DOI: 10.1016/j.cegh.2026.102377
K.K. Ashwin Raj, Mubarack Sani, Anaan Basha, Hiba Shaji, Krishnaraj Rajeev, K.P. Aiswarya
{"title":"The hidden burden of undiagnosed diabetic kidney disease in primary care: Lessons from a rural Indian health system","authors":"K.K. Ashwin Raj,&nbsp;Mubarack Sani,&nbsp;Anaan Basha,&nbsp;Hiba Shaji,&nbsp;Krishnaraj Rajeev,&nbsp;K.P. Aiswarya","doi":"10.1016/j.cegh.2026.102377","DOIUrl":"10.1016/j.cegh.2026.102377","url":null,"abstract":"<div><h3>Background</h3><div>Diabetic kidney disease (DKD) is a major contributor to chronic kidney disease and related morbidity among individuals with type 2 diabetes mellitus. Early detection can delay disease progression; however, DKD often remains undiagnosed in primary-care settings, particularly in rural health systems. Evidence on the magnitude of undiagnosed DKD within routine diabetes care in India remains limited.</div></div><div><h3>Methods</h3><div>A community-based cross-sectional analytical study was conducted from May to June 2024 among adults with type 2 diabetes mellitus attending primary-care services in a rural area of Kerala, India. Sociodemographic, clinical, and laboratory data were collected using structured interviews and medical record review. Estimated glomerular filtration rate (eGFR) was calculated using the Modification of Diet in Renal Disease equation. Undiagnosed DKD was defined as chronic kidney disease (eGFR &lt;60 mL/min/1.73 m<sup>2</sup>) in individuals without a prior documented diagnosis. Descriptive analyses, group comparisons, and logistic regression were performed.</div></div><div><h3>Findings</h3><div>Among 110 participants, 22.7% (95% CI: 15.0–30.5%) were identified with previously undiagnosed DKD, with all cases first detected at stage 3 or beyond. Individuals with undiagnosed DKD showed a significantly higher prevalence of elevated serum creatinine, anaemia, hyperkalaemia, and poor glycaemic control. Documentation of urine albumin testing and prior eGFR calculation was significantly lower among affected participants. In multivariable analysis, older age, hypertension, longer duration of diabetes, and higher serum creatinine levels were independently associated with undiagnosed DKD. The multivariable logistic regression model demonstrated good discriminatory performance, with an area under the receiver operating characteristic curve (AUC) of 0.89 (95% CI: 0.82–0.95).</div></div><div><h3>Interpretation</h3><div>A substantial hidden burden of undiagnosed diabetic kidney disease exists within routine primary-care diabetes services, with detection occurring predominantly at advanced stages. These findings indicate missed opportunities for early diagnosis despite regular health-system contact and highlight the need to strengthen systematic renal assessment within existing primary-care programmes.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"39 ","pages":"Article 102377"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147850747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autism spectrum disorders with comorbidities – A detailed profiling of risk factors and temperamental characteristics - Insights from a tertiary care center 具有合并症的自闭症谱系障碍-风险因素和气质特征的详细分析-来自三级保健中心的见解
IF 1.7
Clinical Epidemiology and Global Health Pub Date : 2026-05-01 Epub Date: 2026-04-29 DOI: 10.1016/j.cegh.2026.102364
Ushasti Sinha , Sujay Shenoy , Amrtavarshini Radhakrishna, Rajeshkrishna Panambur Bhandary
{"title":"Autism spectrum disorders with comorbidities – A detailed profiling of risk factors and temperamental characteristics - Insights from a tertiary care center","authors":"Ushasti Sinha ,&nbsp;Sujay Shenoy ,&nbsp;Amrtavarshini Radhakrishna,&nbsp;Rajeshkrishna Panambur Bhandary","doi":"10.1016/j.cegh.2026.102364","DOIUrl":"10.1016/j.cegh.2026.102364","url":null,"abstract":"<div><h3>Background</h3><div>The prevalence of autism spectrum disorders (ASD) is rising worldwide. Psychiatric/physical comorbidities are common in ASD and untreated comorbidities worsen functioning. Understanding the risk factors and temperamental characteristics in ASD with comorbidities helps to inform preventive and early intervention efforts.</div></div><div><h3>Methods</h3><div>Data was collected from medical case records of children with ASD, aged 17 years and below, evaluated under the Department of Psychiatry, between January 2014 and December 2024. 120 clinical records with an ASD diagnosis were screened, out of which 46 were included for the study. The records were systematically scrutinized for risk factors, temperamental characteristics, symptoms of ASD and comorbidities according to ICD-11.</div></div><div><h3>Results</h3><div>74% of the children were aged 5 years or below. 48% had medical comorbidities, and 84.8% had psychiatric comorbidities. 43% and 32% had a family history of medical and psychiatric comorbidities, respectively. Among pre- and perinatal risk factors, 30% (14) had at least a single risk factor, and 52% (24) had more than one risk factor. Children with comorbidities had a higher median number of risk factors (2 vs 1). 48% of children had a difficult temperament, and all of them had comorbidities with ASD. Among these, the dimensions of temperament were heterogeneous.</div></div><div><h3>Conclusion</h3><div>Our study highlights the importance of detailed risk factor profiling and temperamental characteristics of ASD with comorbidities for preventive, promotion, and early intervention for ASD.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"39 ","pages":"Article 102364"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147850748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in cataract and glaucoma surgery in the Brazilian unified health system: a retrospective study from 2009 to 2024 巴西统一卫生系统白内障和青光眼手术趋势:2009年至2024年的回顾性研究
IF 1.7
Clinical Epidemiology and Global Health Pub Date : 2026-05-01 Epub Date: 2026-04-28 DOI: 10.1016/j.cegh.2026.102372
Carolina Engelbrecht, Marina Martins Siqueira, Gabriely Rangel Pereira, Lucas Hernandes Correa, Nelson Wolosker, Marcelo Passos Teivelis
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