Clinical Epidemiology and Global Health最新文献

{"title":"Vitamin B12 deficiency and associated factors in pregnancy, Puducherry: A community based cross-sectional analytical study","authors":"Akshya Priya Subramanian,&nbsp;Karthik Rajan Parasuraman Udayakumar,&nbsp;Ruben Raj,&nbsp;Venkatachalam Jayaseelan,&nbsp;Sasirekha Rengaraj,&nbsp;Nivedita Nanda","doi":"10.1016/j.cegh.2026.102473","DOIUrl":"10.1016/j.cegh.2026.102473","url":null,"abstract":"<div><div>Vitamin B12 deficiency affects 26–51% of pregnant women in low andmiddle-income countries. Deficiency remains undetected due to a lack of screening; hence, ourstudy focused on screening pregnant women during their ANC visits at Primary Health Centres(PHC), Puducherry, to determine the prevalence and factors associated with the deficiency.Methods: A cross-sectional study was conducted among pregnant women (≥18 years) receivingANC care in PHC. The sample size was calculated as 234, derived by anticipating a prevalence of55% and an absolute precision of 7%. Six PHCs in Puducherry district were selected by simplerandom sampling, and 39 participants from each PHC were selected consecutively.Sociodemographic, dietary, and clinical data were collected using a semi-structured questionnaire.Blood samples were analyzed for plasma vitamin B12. Prevalence was reported with proportion anda 95% Confidence Interval. Associated factors were analyzed using multivariable log-binomialregression for adjusted prevalence ratio (aPR). Results: The mean (SD) age of participants was 27.3(4.05) years; 45% were in their second trimester, and nearly 75% were homemakers. Most (97%) ofthem consumed a nonvegetarian diet, though only half met recommended B12 intake. Theprevalence of vitamin B12 deficiency (&lt;200 pg/ml) was 82.9% (n=194) [95% CI: 77.5–87.1].Employment status was significantly associated with deficiency (aPR = 1.13; 95% CI: 1.02–1.28)after adjusting for gravida, dietary intake, and anemia. Conclusion: Vitamin B12 deficiency washighly prevalent among pregnant women in Puducherry. Employment status emerged as asignificant factor associated with the deficiency.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102473"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of digital health technologies in the management of hypertension and diabetes in rural populations: a systematic review","authors":"Vaibhav Chaudhary,&nbsp;Bhavya Sharma,&nbsp;Sweta Kumari,&nbsp;Tambe Daniel Atem,&nbsp;Molakpogu Ravindra Babu,&nbsp;Krishna Murti,&nbsp;Nitesh Kumar,&nbsp;Biplab Pal","doi":"10.1016/j.cegh.2026.102470","DOIUrl":"10.1016/j.cegh.2026.102470","url":null,"abstract":"<div><h3>Background</h3><div>The rising prevalence of hypertension and diabetes presents significant challenges for management, especially in rural areas where healthcare resources are limited. This systematic review examined the potential of digital health technologies in managing these conditions in rural populations.</div></div><div><h3>Methods</h3><div>Search was conducted across PubMed, Scopus, EMBASE, and Google Scholar for studies published from the earliest records indexed in each database up to September 2025 that assessed the effectiveness of digital health interventions in managing diabetes and/or hypertension in rural areas. Quality assessment was performed using Revised Cochrane Risk-of-Bias Tool (RoB 2.0) and Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I) tool.</div></div><div><h3>Results</h3><div>A total of 11 studies were included, with 3 focusing on hypertension, 7 on diabetes, and 1 on both conditions. Digital interventions for hypertension were associated with reductions in blood pressure and improvements in quality of life, treatment adherence, and self-efficacy. Similarly, interventions for diabetes were associated with reductions in blood glucose levels or HbA1c and improvements in LDL levels and self‐management skills. However, no significant changes were observed in HDL levels, triglycerides, albumin-to-creatinine ratio, body mass index, or waist circumference.</div></div><div><h3>Conclusion</h3><div>Digital health interventions show potential to support the management of hypertension and diabetes in rural populations by improving clinical and behavioral outcomes. However, factors such as low digital literacy, language barriers, poor internet connectivity, and limited access to digital devices may affect implementation. Future research should evaluate interventions that are appropriate for rural settings to improve the management of these chronic conditions.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102470"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of maternal Moringa oleifera–royal jelly supplementation on the infant gut microbiota at six months in rural Indonesia","authors":"Syamsul Alam,&nbsp;Veni Hadju,&nbsp;Ansariadi,&nbsp;Nurhaedar Jafar,&nbsp;Muh Tahir Abdullah,&nbsp;Syamsuar Manyullei","doi":"10.1016/j.cegh.2026.102463","DOIUrl":"10.1016/j.cegh.2026.102463","url":null,"abstract":"<div><h3>Background</h3><div>Maternal nutrition during pregnancy influences the early establishment of the infant gut microbiota, yet the impact of food-based interventions combining <em>Moringa oleifera</em> and royal jelly, particularly in low-resource settings such as Indonesia, remains underexplored. This study aimed to evaluate the effects of maternal <em>Moringa oleifera</em>–royal jelly (MRJ) supplementation during pregnancy on the abundance of five predefined infant gut bacterial genera at six months of age.</div></div><div><h3>Methods</h3><div>A follow-up randomized controlled trial involving 88 mother–infant pairs was conducted in rural Banggai, Indonesia. Pregnant women received either MRJ or multiple micronutrient supplements (MMS) from the second trimester until delivery. Infant fecal samples collected at six months were analyzed using quantitative real-time PCR targeting five dominant bacterial genera (<em>Bifidobacterium</em>, <em>Lactobacillus</em>, <em>Bacteroides</em>, <em>Clostridium</em>, and <em>Escherichia coli</em>). Associations were examined using generalized linear models adjusted for maternal, infant, environmental, and breastfeeding-related factors.</div></div><div><h3>Results</h3><div>The infant gut microbiota was dominated by <em>Bifidobacterium</em> and <em>Lactobacillus</em>, with a higher combined abundance of beneficial than opportunistic genera (p = 0.0017). No significant differences in genus-level abundance were observed between MRJ and MMS groups. In adjusted generalized linear models, MRJ supplementation was not associated with any of the five assessed genera (all p &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>Maternal MRJ supplementation was not associated with differences in the abundance of the five assessed bacterial genera at six months compared with MMS. These findings suggest that MRJ may serve as a safe food-based strategy that complements MMS within antenatal nutrition programs.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102463"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148952019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Beyond prevention: Optimizing reproductive health choices for people living with HIV in India – A look at contraceptive use and unmet need from National Family Health Survey-4 data” [Clin Epidemiol Glob Health 39 (2026) 102351]","authors":"Nishanth Krishna Kodyalamoole,&nbsp;Ankeeta Menona Jacob","doi":"10.1016/j.cegh.2026.102450","DOIUrl":"10.1016/j.cegh.2026.102450","url":null,"abstract":"","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102450"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149050803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community-based prevalence of tobacco pouch keratosis in India: A systematic review and meta-analysis, 2000-2025","authors":"Chandru Sivamani,&nbsp;Lavanya Ayyasamy,&nbsp;Revathy Ajayan,&nbsp;Kavya S.,&nbsp;Mamta Mor,&nbsp;Kavipriya Outtamane,&nbsp;Swetha Durai,&nbsp;Sooriyaprasannan Sriram,&nbsp;Sombuddha Biswas","doi":"10.1016/j.cegh.2026.102466","DOIUrl":"10.1016/j.cegh.2026.102466","url":null,"abstract":"<div><h3>Problem considered</h3><div>Tobacco pouch keratosis (TPK) is an oral potentially malignant disorder (OPMD) that remains poorly studied in India due to fragmented and geographically heterogeneous evidence. We estimated the community-based pooled prevalence (CBPP) of TPK and examined variations by region and population characteristics.</div></div><div><h3>Methods</h3><div>This review was registered in PROSPERO and conducted in accordance with the PRISMA guidelines. PubMed, EMBASE, and Scopus were searched for community-based studies published since 2000, supplemented by citation tracking. A random-effects meta-analysis using logit transformation was performed to estimate the CBPP of TPK with 95% confidence intervals (CIs). Prediction interval, subgroup analyses, publication bias, and sensitivity analysis were also assessed.</div></div><div><h3>Results</h3><div>Thirteen studies comprising 16,169 participants and 668 TPK cases were included. The CBPP of TPK across the included studies was 3.0% (95% CI: 1.0-8.0), with substantial heterogeneity (I² = 99.2%). Prevalence was higher in the Eastern region (23.0%; 95% CI: 17.0–29.0) followed by the Northern region (9.0%; 95% CI: 6.0–13.0). Tribal populations had a higher prevalence (9.0%; 95% CI: 2.0–28.0) than occupational groups (5.0%; 95% CI: 1.0–28.0). Leave-one-out analysis supported the stability of the pooled estimate, while Egger's test suggested small-study effects (<em>p</em> = 0.0009).</div></div><div><h3>Conclusion</h3><div>The pooled estimate reflects heterogeneous community-based evidence rather than a precise national estimate, with substantial variation across geographical regions and population groups. Targeted tobacco-control and prevention strategies, alongside longitudinal community-based studies, are needed to better characterize the prevalence of TPK and its malignant transformation potential.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102466"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A bibliometric review of diabetic foot-related research in Southeast Asian countries in Scopus (1974-2025)","authors":"Chan Junji,&nbsp;Atiqah Ab Aziz,&nbsp;Tan Han Ling,&nbsp;Sudarsan Swain,&nbsp;Azura Mansor,&nbsp;Tunku Kamarul","doi":"10.1016/j.cegh.2026.102476","DOIUrl":"10.1016/j.cegh.2026.102476","url":null,"abstract":"<div><div>Southeast Asia (SEA) bears one of the highest burdens of Diabetic Foot-related Disease (DFD) in the Western Pacific, yet research from the region has been underrepresented. <strong>This study is the first comprehensive effort to map and showcase 50 years of DFD research, addressing a critical knowledge gap.</strong> We conducted a bibliometric analysis of SEA's DFD research using the Scopus database and VOSviewer software (search conducted on March 2025). 722 out of 2782 publications met the inclusion criteria, where cross-sectional studies and experimental-based studies were the most common study designs. Publication output grew nearly seven-fold between 2015 and 2024. Co-occurrence mapping revealed major research themes: laboratory-based wound healing studies (n = 351 items), risk factors and prevention of DFD, complications of diabetic foot ulcer (DFU) and their management, patient self-care and prevention, diabetic foot infection and pharmacological-based DFD wound healing. The top-cited paper received 272 citations, underscoring the region's DFD global research relevance. International collaborations were common, especially with India, the United States and Japan, though broader engagement with global research networks remains limited. Despite increasing research activity, locally generated, high-quality clinical trials are still scarce. Strengthening investment in region-specific, evidence-based research will be crucial to inform tailored policies and interventions for Southeast Asian populations, bringing valuable input to the global DFD-database from the local perspective.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102476"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping global research on environmental enteric dysfunction: A bibliometric study of trends and emerging themes","authors":"Eri Wijaya,&nbsp;Ansariadi,&nbsp;Veni Hadju,&nbsp;Rizalinda Sjahril,&nbsp;Asri C. Adisasmita,&nbsp;Anwar Mallongi,&nbsp;Suparmi,&nbsp;Esti Nugraheny","doi":"10.1016/j.cegh.2026.102471","DOIUrl":"10.1016/j.cegh.2026.102471","url":null,"abstract":"<div><h3>Problem considered</h3><div>Environmental enteric dysfunction (EED) is a subclinical inflammatory disorder of the small intestine that results in nutrient malabsorption, stunting, impaired cognitive development, and adverse pregnancy outcomes. It disproportionately affects populations in low- and middle-income countries, where chronic exposure to enteric pathogens and poor sanitation is common. Despite growing recognition as a global health concern, EED remains poorly defined, with no standardized diagnostic tools. This bibliometric analysis examines research trends, leading contributors, and emerging themes to inform future research directions.</div></div><div><h3>Methods</h3><div>The study analyzed publications related to EED retrieved from the Scopus database, covering the period 1972 to 2024. Data cleaning was performed using OpenRefine. Keyword co-occurrence network analysis was conducted using VOSviewer, while trend and collaboration analyses were carried out in R Studio, and geographic visualization in Tableau.</div></div><div><h3>Results</h3><div>From 1972 to 2024, 484 publications on EED were identified, with an annual growth rate of 5.06%. Output increased markedly after 2010, driven by growing recognition of EED in child growth and malnutrition. The United States and the United Kingdom led publication output, while Bangladesh, Pakistan, and India were the most active LMICs, though their contributions remain low relative to disease burden. Research focus has shifted from basic pathology to multidisciplinary areas, including microbiota, biomarkers, and WASH-related determinants.</div></div><div><h3>Conclusion</h3><div>EED research has expanded over five decades, evolving from a focus on malnutrition to biomarkers and mechanistic studies. However, geographic imbalances persist, underscoring the need to strengthen research capacity, promote equitable collaborations, and translate mechanistic insights into scalable, context-appropriate interventions.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102471"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148952017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and regional variations of ischemic heart disease and liver cirrhosis-related mortality among American adults (1999-2023)","authors":"Farah Yasmin,&nbsp;Abdul Moeed,&nbsp;Muhammad Ahmed Ali Fahim,&nbsp;Muhammad Omar Larik,&nbsp;Ali Abbas Mankani,&nbsp;Muhammad Sohaib Asghar,&nbsp;Salim Surani","doi":"10.1016/j.cegh.2026.102469","DOIUrl":"10.1016/j.cegh.2026.102469","url":null,"abstract":"<div><h3>Problem considered</h3><div>Liver cirrhosis (LC) is linked to ischemic heart disease (IHD). This study investigates mortality trends due to concurrent LC and IHD using national-level data in the U.S.</div></div><div><h3>Methods</h3><div>This retrospective, population-based descriptive study utilized the CDC WONDER (Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research) database to retrieve mortality data among adults aged ≥25 years from 1999 to 2023. Crude rates (CRs), age-adjusted mortality rates (AAMRs) per 100,000 population, and annual percentage changes (APCs) with 95% confidence intervals (CIs) were calculated, and data were stratified by year, sex, race, urbanization, and state.</div></div><div><h3>Results</h3><div>Among 113,089 deaths, AAMRs decreased from 1999 to 2009 (APC: −1.16; 95% CI: −1.97 to −0.60), increased from 2009 to 2018 (APC: 2.71; 95% CI: 1.80 to 3.51), and rose sharply from 2018 to 2021 (APC: 9.72; 95% CI: 7.56 to 11.15). Rates between 2021 and 2023 were stable. (APC: 0.35; 95% CI: −1.95 to 2.93) Males had triple the AAMRs compared to females (3.08 vs 1.01). Non-Hispanic (NH) American Indian/Alaska Natives had the highest AAMRs (4.05), while NH Asian/Pacific Islanders (0.99) had the lowest. AAMRs in the West (2.14) were the highest, followed by the South (2.12), Midwest (1.77), and Northeast (1.66). Nonmetropolitan areas had higher AAMRs than metropolitan ones (1.96 vs 1.84). States in the top 90th percentile of crude mortality rates included West Virginia (CR: 3.89), Rhode Island (CR: 3.63), Oklahoma (CR: 3.29), Texas (CR: 3.01), and Vermont (CR: 3.01).</div></div><div><h3>Conclusion</h3><div>Mortality due to concurrent LC and IHD has risen in recent years, remaining higher in men, NH American Indian/Alaska Natives, nonmetropolitan areas, and the West, underscoring the need for strategic interventions to mitigate these disparities.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102469"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148952018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, regional variations and factors associated with resistant hypertension in India: A systematic review and meta-analysis","authors":"Mokanpally Sandeep,&nbsp;Maleese Surya Durga Prasad,&nbsp;Dandu Akshitha,&nbsp;Sree Sudha Tanguturi Yella,&nbsp;Muhammad Aaqib Shamim,&nbsp;L Ananthesh,&nbsp;B. Ramaswamy Shamanna,&nbsp;Dandge Shailendra,&nbsp;Mohammad Sohail Akhter","doi":"10.1016/j.cegh.2026.102467","DOIUrl":"10.1016/j.cegh.2026.102467","url":null,"abstract":"<div><h3>Background</h3><div>Resistant hypertension (RH) raises the risk of adverse cardiovascular and renal outcomes. Data on RH burden across India remain fragmented. This systematic review and meta-analysis estimated pooled prevalence, regional variations, and factors associated with RH among hypertensive adults in India.</div></div><div><h3>Methods</h3><div>We searched PubMed, Scopus, and EBSCOhost: Academic Search Complete for studies reporting RH prevalence among Indian hypertensive adults published until November 2025. Pooled prevalence and odds ratios were estimated using a random-effects model. Heterogeneity was assessed using I² statistic and 95% confidence and prediction intervals. Quality was assessed using the NHLBI tool, and publication bias using the Doi plot and LFK index. The protocol was registered with OSF, and reporting followed PRISMA 2020 guidelines.</div></div><div><h3>Results</h3><div>Thirteen studies comprising 14,311 hypertensive patients were included. The pooled prevalence of RH was 19% (95% CI, 11–30%), with substantial heterogeneity (I² = 98.2%) and a wide prediction interval (2–70%). Regional pooled estimates ranged from 14% in the East to 22% in the West; however, the between-region difference was not statistically significant (p = 0.86). Diabetes (OR 2.95), obesity (OR 3.81), and dyslipidaemia (OR 1.83) showed positive but nonsignificant associations. The Doi plot symmetry and LFK index (0.15) indicated a low likelihood of publication bias.</div></div><div><h3>Conclusion</h3><div>RH appears common among hypertensive adults in India. However, substantial heterogeneity and a wide prediction interval limit the generalizability of the pooled estimate. Regional differences were not statistically significant, and cardiometabolic associations were inconclusive. Standardised diagnostic criteria and region-specific research are needed to clarify the burden and guide management.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102467"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mobile health interventions for primary cardiovascular disease prevention in perimenopausal women: A scoping review","authors":"Dua' Y. Al-Maharma,&nbsp;Hanan H. Sabah,&nbsp;Mohammad Y.N. Saleh","doi":"10.1016/j.cegh.2026.102445","DOIUrl":"10.1016/j.cegh.2026.102445","url":null,"abstract":"<div><h3>Background/objectives</h3><div>Perimenopause is characterized by cardiometabolic and hormonal changes that increase cardiovascular disease (CVD) risk. Mobile health (mHealth) technologies may support cardiovascular health. This scoping review mapped the evidence on mHealth interventions for CVD prevention among perimenopausal women.</div></div><div><h3>Methods</h3><div>Interventional and observational studies were included. MEDLINE Complete, ScienceDirect, Scopus, and Web of Science were searched for studies published between January 2014 and January 2026, following JBI methodology.</div></div><div><h3>Results</h3><div>Twelve studies were included, mostly from high-income countries. Only one intervention was tailored to menopause. Mobile app–based interventions were most common; outcomes were mainly assessed by individual risk factors rather than composite CVD risk scores.</div></div><div><h3>Conclusions</h3><div>Menopause-tailored pragmatic studies in LMICs, including Arab countries, are needed.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"41 ","pages":"Article 102445"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}