Clinical Epidemiology and Global Health最新文献

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Comparison of sonographic score and Bishop score in the prediction of successful labor induction in term patients: A prospective observational study "超声评分与毕夏普评分在预测足月患者引产成功率方面的比较:前瞻性观察研究"。
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-11-01 DOI: 10.1016/j.cegh.2024.101734
{"title":"Comparison of sonographic score and Bishop score in the prediction of successful labor induction in term patients: A prospective observational study","authors":"","doi":"10.1016/j.cegh.2024.101734","DOIUrl":"10.1016/j.cegh.2024.101734","url":null,"abstract":"<div><h3>Background</h3><div>The cervical favorability for IOL is assessed by scoring systems. There are various scoring systems, including the Field system, Lange pelvic scoring system, and Bishop scoring system, which was then modified and termed ‘The modified Bishop scoring system, and it is the most widely used one. This scoring is done based on the assessment of the station of the fetal presenting part, consistency, position, dilatation, and length of the maternal cervix. Owing to its subjective assessment, there is a high chance of inter-observer variability. Therefore, radiological methods such as <em>Trans</em>-vaginal ultrasonogram (TVS) and <em>Trans</em>-abdominal ultrasonogram (TAS) are preferred over manual methods. This study aims to determine the role of assessment of the cervix by Modified Bishop Score and assessment of the cervical parameters by Transvaginal ultrasonogram (TVS) and compare them in predicting the outcome of labour.</div></div><div><h3>Material and methods</h3><div>This prospective observational study was conducted by the Department of Obstetrics and Gynecology in a tertiary care hospital located at Chengalpattu, Tamil Nadu, in a term singleton pregnancy woman, and the Study period was from January 2023 to July 2023 for six months. In total, one hundred fifty pregnant women were recruited. The study inclusion criteria were singleton pregnant women with intact amniotic membranes and a period of gestation &gt;37 weeks with cephalic presentation. The findings of TVS were blinded to the person who measured cervical parameters for the bishop score. IOL done for both favorable and unfavorable cervix according to the guidelines given by FOGSI-ICOG (2018) for IOL.</div></div><div><h3>Results</h3><div>Receiver operating characteristic (ROC) curve analysis showed the area under the curve (AUC) for the TVS score was 0.705(95 % CI: 0.616–0.794) against the standard bishop score. TVS Score≥6.5 cm is the best cut-off value to ascertain successful IOL with a sensitivity of 99 % and specificity of 94 % among singleton pregnancy women.</div></div><div><h3>Conclusion</h3><div>This prospective observational study deduced that TVS scoring is a valid alternative tool against the standard bishop score in predicting cervical favorability for IOL among singleton pregnant women with plausible sensitivity and specificity. TVS scoring for assessing cervical favorability acts as an outstanding marker in predicting the IOL with a cut-off value of ≥6.5 cm in singleton pregnant women.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141842976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arabic validation and cross-cultural adaptation of climate anxiety scale 气候焦虑量表的阿拉伯语验证和跨文化调整
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-11-01 DOI: 10.1016/j.cegh.2024.101835
{"title":"Arabic validation and cross-cultural adaptation of climate anxiety scale","authors":"","doi":"10.1016/j.cegh.2024.101835","DOIUrl":"10.1016/j.cegh.2024.101835","url":null,"abstract":"<div><h3>Background</h3><div>Climate change is an enduring global phenomenon that describes a long-lasting effect of change in weather and temperature of the earth. This study aimed to validate an Arabic version of the Climate Anxiety Scale (ACAS) to assess the anxiety associated with climate change.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted using both online via Google Forms and face-to-face via hard copies, in five Arab countries, Lebanon, Palestine, Egypt, Saudia Arabia, and the United Arab Emirates). The internal consistency of the scale was assessed using the Cronbach's alpha. Exploratory factor analysis (EFA) conducted over principal component analysis assessed the scale dimensionality. Then, confirmatory factor analysis was conducted to investigate the EFA hypothesis of ACAS on anxiety about climate change.</div></div><div><h3>Results</h3><div>Of the 350 participants, 54.9 % were female, 77.7% lived in urban areas, 15.4% were from North Africa, 46.6 % were from Arab Gulf countries, and 38.0 % were from Bilad Al-Sham. Nearly two-thirds (62.3%) were single, 72.3% had a university degree, 94.9% were aware of climate change, 38.3 % participated in environmental protection programs, and 62.3% reported climate-related anxiety. The item content validity index (CVI) was 0.82–1.00, and the scale CVI (S-CVI) was 0.95. Overall Cronbach's alpha was 0.925 with a 95% confidence interval (CI) [0.902–0.940]. The Kaiser-Mayer-Olkin (KMO) test was 0.93, and Bartlett's test was significant (χ2 = 2762.6 p &lt; 0.001). Bifactor model indices showed high explained common variance (ECV) (0.78), ωH (0.85), relative omega (0.91), H index (0.93), and factor determinacy (FD) (0.96) for the general factor. The general factor explained 78% of the common variance, whereas the group factors shared 22.0%. Model reliability coefficient omega (omega/omega S) for general factor, functional domain, and cognitive domain were 0.94, 0.92, and 0.89, respectively, suggesting a satisfactory fit threshold.</div></div><div><h3>Conclusions</h3><div>The ACAS tool is valid and reliable for assessing anxiety-related climate change among the Arab Population.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroprevalence of strongyloidiasis and toxocariasis among hypereosinophilic patients seeking care at diagnostic centers in Tehran, Iran 在伊朗德黑兰诊断中心就诊的嗜酸性粒细胞过多症患者中强直性脊柱炎和弓形虫血清流行率
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-11-01 DOI: 10.1016/j.cegh.2024.101826
{"title":"Seroprevalence of strongyloidiasis and toxocariasis among hypereosinophilic patients seeking care at diagnostic centers in Tehran, Iran","authors":"","doi":"10.1016/j.cegh.2024.101826","DOIUrl":"10.1016/j.cegh.2024.101826","url":null,"abstract":"<div><h3>Background</h3><div>Hypereosinophilia is characterized by an increase in eosinophil levels above the normal range. Secondary hypereosinophilia is frequently seen in helminth infections and allergic conditions. If not diagnosed and managed promptly, eosinophilia can result in various complications impacting health. The aim of this study was to explore the seroprevalence of <em>Strongyloides stercoralis</em> and <em>Toxocara</em> spp. among hypereosinophilic patients undergoing evaluation at selected diagnostic centers in Tehran<strong>.</strong></div></div><div><h3>Methods</h3><div>A comprehensive questionnaire was completed, and a blood sample was collected from each participant. The seropositivity of helminth infections was ascertained through indirect enzyme-linked immunosorbent assay (ELISA) employing commercially procured kits for discerning anti-<em>S. stercoralis</em> and anti-<em>Toxocara</em> spp. IgG antibodies. Statistical analysis was conducted using SPSS 21 software.</div></div><div><h3>Results</h3><div>Of the 135 participants in this study, 61 (45.2 %) were male and 74 (54.8 %) were female. The seropositivity rates for strongyloidiasis and toxocariasis were found to be 9.6 % and 0.74 %, respectively. Among the various underlying medical conditions observed in the participants, Type 2 Diabetes (T2D) was the most prevalent, and it showed a significant association with seropositivity for strongyloidiasis (p &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>The seropositivity for <em>S. stercoralis</em> was higher than that for <em>Toxocara</em> spp.. The significant association between seropositivity for <em>S. stercoralis</em> and diabetes underscores the importance of conducting community-based studies and implementing screening initiatives targeting high-risk populations to assess the seroprevalence of strongyloidiasis.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of malignant neoplasms and organizational aspects of cancer care in the Republic of Kazakhstan 哈萨克斯坦共和国恶性肿瘤发病率和癌症治疗的组织方面
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-11-01 DOI: 10.1016/j.cegh.2024.101838
{"title":"Incidence of malignant neoplasms and organizational aspects of cancer care in the Republic of Kazakhstan","authors":"","doi":"10.1016/j.cegh.2024.101838","DOIUrl":"10.1016/j.cegh.2024.101838","url":null,"abstract":"<div><h3>Background</h3><div>This study aims to investigate the incidence and mortality rates of malignant neoplasms in Kazakhstan in 2022 and to analyze the organizational aspects of cancer care.</div></div><div><h3>Methods</h3><div>Data from 33,177 patients with malignant neoplasms registered in oncological institutions in 2022 were analyzed. The study focused on treatment completion rates and the distribution of treatment modalities, including surgical, radiation, medicinal, combined, comprehensive, and chemo-radiation therapies. Comparative analysis with international data was conducted to assess the effectiveness and adherence to global oncological standards.</div></div><div><h3>Results</h3><div>The analysis revealed that 55.2 % of patients completed specialized treatment, with complex treatment being the most common modality (94.3 %). High completion rates were observed in breast cancer (65.9 %) and cervical cancer (68.8 %), reflecting the effectiveness of early detection and multidisciplinary approaches. However, lower completion rates were noted in liver cancer (26.2 %) and leukemia (23.0 %), highlighting the need for improved diagnostic and treatment strategies. Comparative international data indicated similar trends, with countries like the USA, UK, Japan, and Australia demonstrating the effectiveness of multidisciplinary and comprehensive treatment approaches.</div></div><div><h3>Conclusion</h3><div>The study underscores the importance of a multidisciplinary approach in treating malignant neoplasms, with Kazakhstan's practices largely aligning with international standards. Nevertheless, there is a need to enhance early diagnosis and treatment completion rates for specific cancers such as liver cancer and leukemia. Strengthening screening programs, improving access to modern treatments, and integrating international best practices can further improve patient outcomes in Kazakhstan.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neutralizing antibody titers after COVID-19 vaccination 接种 COVID-19 疫苗后的中和抗体滴度
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-11-01 DOI: 10.1016/j.cegh.2024.101819
{"title":"Neutralizing antibody titers after COVID-19 vaccination","authors":"","doi":"10.1016/j.cegh.2024.101819","DOIUrl":"10.1016/j.cegh.2024.101819","url":null,"abstract":"<div><h3>Background</h3><div>Monitoring COVID-19 and evaluating the effectiveness of prevention and control strategies are considered critical priorities in public health. As a result, the administration of COVID-19 vaccines has been widely approved around the world. In the current study, we investigated the level of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) neutralizing antibody (NAb) among individuals who received different COVID-19 vaccines.</div></div><div><h3>Methods</h3><div>This cross-sectional study recorded demographical data and clinical characteristics of 168 individuals who received COVID-19 vaccines from 2021 to 2022. Vaccination data of participants, including type and times of vaccine and any complications and symptoms after vaccination, were also recorded. SARS-CoV-2 NAb level was assessed by performing an ELISA test, and all data was analyzed using SPSS version 21. The significant level was set at 0.05.</div></div><div><h3>Results</h3><div>The mean age of the participants was 40.4 ± 16 years, and 109 were females. About 18.4 % of participants had the underlying diseases, of which thyroid diseases were the most frequent. The mean SARS-CoV-2 NAb level was 31.6 ± 39.78 ng/ml. Sinopharm was the common vaccine in our population, and AstraZeneca represented a high level of Nab 47.18 ng/ml. Among the participants, 96 had mild to severe complications after vaccination, with the most complaining of arm pain. Significant differences of NAb levele were observed only between types of vaccine and gender (P &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Due to our findings, all employed vaccines demonstrated efficacy in generating NAb. The levels of Nab were different among genders, age groups, and different types of vaccine receivers.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“A study on socio-demographic-based knowledge and awareness for cervical cancer among women from Uttar Pradesh, India” "关于印度北方邦妇女对宫颈癌的社会人口学知识和认识的研究"。
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-11-01 DOI: 10.1016/j.cegh.2024.101825
{"title":"“A study on socio-demographic-based knowledge and awareness for cervical cancer among women from Uttar Pradesh, India”","authors":"","doi":"10.1016/j.cegh.2024.101825","DOIUrl":"10.1016/j.cegh.2024.101825","url":null,"abstract":"<div><h3>Background</h3><div>Cervical cancer has led to unprecedented mortality in developing countries, including India. Socio-demographic factors are known to influence knowledge of cervical cancer, screening practices, and HPV vaccination. This study aims to assess cervical cancer awareness and vaccination willingness among women in Uttar Pradesh, India, and identify key socio-demographic determinants.</div></div><div><h3>Methods</h3><div>A clinical and community-based survey in northern India was conducted with a total of 666 women of ≥20 years of age. The survey, developed and verified through expert consultation and pilot testing, covered socio-demographics, cervical cancer knowledge, symptoms, HPV awareness, and vaccine attitudes. Online, offline, and targeted outreach distributed the questionnaire randomly to the general public. Data was analyzed using SPSS 16.0 descriptive statistics, cross-tabulation, and chi-square testing.</div></div><div><h3>Results</h3><div>Among the 666 participants involved in this survey, 516 women (77.5 %) were acquainted with the word “cervical cancer”. Only 235 (45.57 %) of the female participators had sound understanding with regard to cervical cancer symptoms (mean score: 7.7); however, it was less in women dwelling in rural areas (p &lt; 0.05). In less or uneducated women, low-income household women, and rural dwellers, the knowledge regarding HPV-mediated cervical cancer and willingness to get vaccinated against HPV were low (p &lt; 0.05 and p &lt; 0.001, respectively).</div></div><div><h3>Conclusion</h3><div>This study reveals critical gaps in cervical cancer awareness and vaccination willingness, particularly among socio-economically disadvantaged and rural women. In impoverished areas, targeted public health interventions including information campaigns and affordable HPV vaccines are needed to improve early stage identification and prevention.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Educational intervention to raise awareness and foster responsibility for Chagas disease risk factors in the rural community of Texca, Guerrero, Mexico.” 在墨西哥格雷罗州特克斯卡农村社区开展教育干预活动,提高对南美锥虫病风险因素的认识并培养责任感"。
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-11-01 DOI: 10.1016/j.cegh.2024.101831
{"title":"Educational intervention to raise awareness and foster responsibility for Chagas disease risk factors in the rural community of Texca, Guerrero, Mexico.”","authors":"","doi":"10.1016/j.cegh.2024.101831","DOIUrl":"10.1016/j.cegh.2024.101831","url":null,"abstract":"<div><h3>Problem considered</h3><div>Chagas disease is a vector-borne parasitic infection considered of public health importance. For farmers and residents of endemic areas, vectors are part of their day to day life and they often lack awareness of their infectious potential, so the risk they pose is not a main concern in their lives. So far, existing measures set in place to eradicate the vector have not been effective long-term.</div></div><div><h3>Methods</h3><div>In this study, a one-year program was designed and implemented to inform and assess the knowledge, attitudes, and perceptions of 81 parents or heads of household regarding the risk of transmission and prevention of <em>Trypanosoma cruzi</em> infection. The program aimed to raise awareness of the crucial role they play in the prevention and control of vectors associated with Chagas disease<strong>.</strong></div></div><div><h3>Results</h3><div>After educational interventions, a notable increase in the percentage of knowledge regarding the parasite, transmission factors, and Chagas disease was observed.</div></div><div><h3>Conclusion</h3><div>This might suggest that properly implementing educational interventions within the population, with training from health professionals and through public programs, will allow for the reduction of infection risks. In the long term, it could significantly reduce the incidence of the disease in the region and state.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dental impact on daily life and oral health in alcohol use disorder patients 牙科对酒精使用障碍患者日常生活和口腔健康的影响
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-11-01 DOI: 10.1016/j.cegh.2024.101836
{"title":"Dental impact on daily life and oral health in alcohol use disorder patients","authors":"","doi":"10.1016/j.cegh.2024.101836","DOIUrl":"10.1016/j.cegh.2024.101836","url":null,"abstract":"<div><h3>Objectives</h3><div>Individuals with Alcohol Use Disorder (AUD) are at a higher risk of developing dental problems. The present study assessed the dental impact on daily performances among AUD patients seeking treatment in a de-addiction centre and correlated it with their clinical dental status using the WHO oral health assessment form (2013).</div></div><div><h3>Materials and methods</h3><div>This research took place from January to May 2022. A cross-sectional study was carried out to collect data from 103 subjects among alcohol dependents taking treatment in a de-addiction centre of Dakshina Kannada district, Karnataka state. The Dental Impact on Daily Living Questionnaire (DIDL) assessed patients' satisfaction with their teeth, while the WHO Oral Health Assessment Form for Adults was used for dental caries (DMFT) and periodontal status. Data analysis was performed using the jamovi open-source software (version 2.3), employing <em>t</em>-test, chi-square test, hierarchical regression analysis, and Spearman correlation coefficient.</div></div><div><h3>Results</h3><div>The study found low yet significant correlations between clinical oral health and dimensions of the DIDL scale. Social class and the number of decayed teeth emerged as significant predictors of the total DIDL score.</div></div><div><h3>Conclusion</h3><div>Oral health conditions can adversely affect patient satisfaction, emphasizing the need for healthcare providers to consider these findings when offering comprehensive oral healthcare services.</div></div><div><h3>Clinical relevance</h3><div>This study underscores the necessity of integrating oral healthcare into the overall treatment regime for individuals with Alcohol Use Disorders (AUDs) to improve their quality of life and satisfaction.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142561067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circulating respiratory viruses including SARS-CoV-2 during 2021–2022 season in Tunisia: Epidemiological and dynamic changes 突尼斯 2021-2022 年季节期间包括 SARS-CoV-2 在内的呼吸道病毒循环:流行病学和动态变化
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-11-01 DOI: 10.1016/j.cegh.2024.101824
{"title":"Circulating respiratory viruses including SARS-CoV-2 during 2021–2022 season in Tunisia: Epidemiological and dynamic changes","authors":"","doi":"10.1016/j.cegh.2024.101824","DOIUrl":"10.1016/j.cegh.2024.101824","url":null,"abstract":"<div><h3>Background</h3><div>Changing patterns in community respiratory virus activity were reported in different geographical locations during the COVID-19 pandemic. In this study, we aimed to assess the prevalence of circulating respiratory viruses, including SARS-CoV-2, during the season 2021–2022 in Tunisia.</div></div><div><h3>Methods</h3><div>We retrospectively enrolled 328 nasopharyngeal samples received at the Triage Center of Habib Bourguiba Hospital from patients with acute respiratory symptoms during September 2021–May 2022. All samples were screened for both SARS-CoV-2 and common respiratory viruses. This latter detection was performed using end-point multiplex RT-PCRs, Real-Time PCR, and AllplexTM Respiratory Panel 1 kit (Seegene) for Influenza Virus A (IFVA) and Respiratory Syncytial Virus (RSV) subtyping.</div></div><div><h3>Results</h3><div>Among included patients, at least one viral pathogen was identified in 118 (35.9 %) patients. The detection rate of SARS-CoV-2 was 21.6 %. A low viral coinfection rate was observed (3.3 %). The most prevalent pathogen among non-SARS-CoV-2 viruses was Enterovirus/Rhinovirus (HEV/HRV) (59.6 %) followed by IFVA (15.3 %) and Adenoviruses (ADV) (11.5 %). Only IFVA H3N2 was found to circulate during the study period. A negative virus interaction was eventually induced by SARS-CoV-2, as it was shown by lower levels of activity of non-SARS-CoV-2 viruses (not exceeding 17.7 %) while infections due to pandemic Omicron variants of concern became widespread.</div></div><div><h3>Conclusions</h3><div>This study highlights the relative return of community IFVA circulation during the 2021–2022 season in Tunisia. A negative viral interaction between SARS-CoV-2 and other respiratory viruses is highly suggested, which explains, in addition to the easing of COVID-19 restriction measures, the epidemiological changes in non-SARS-CoV-2 viruses circulation.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of auditory system in vitiligo patients: A case-control study 评估白癜风患者的听觉系统:病例对照研究
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2024-10-24 DOI: 10.1016/j.cegh.2024.101830
{"title":"Evaluation of auditory system in vitiligo patients: A case-control study","authors":"","doi":"10.1016/j.cegh.2024.101830","DOIUrl":"10.1016/j.cegh.2024.101830","url":null,"abstract":"<div><h3>Background</h3><div>Vitiligo is a common acquired pigmentary disorder characterized by well-defined areas of depigmentation due to loss of melanocytes. Vitiligo can affect melanocytes in the auditory system and potentially hearing.</div></div><div><h3>Objective</h3><div>The aim of this study was to investigate hearing changes in vitiligo patients.</div></div><div><h3>Methods</h3><div>Twenty-six with vitiligo patients and 26 demographically matched healthy controls were included in this study. Audiological function was evaluated using pure tone audiometry (PTA), speech audiometry and tympanometry tests in all subjects.</div></div><div><h3>Results</h3><div>The mean hearing threshold of the left ear at frequencies of 250 and 8000 Hz in vitiligo patients was significantly higher than the control group. Sensorineural hearing loss (SNHL) was seen in 14 (53.8 %) vitiligo patients and 5(19.2 %) control group (p &lt; 0.05). Most affected patients (10/14; 71 %) had bilateral hearing loss especially in high frequency (8000 Hz). A significant association was identified between vitiligo and SNHL (OR 4.9; 95 % CI, 1.41–16.98, P = 0.01). There was a statistically significant correlation between hearing impairment and age in both groups. Gender, severity, activity and duration of vitiligo had no a significant effect on the results of audiometric tests.</div></div><div><h3>Conclusion</h3><div>This study confirmed that the auditory system was affected in vitiligo patients. Vitiligo patients might be at a higher risk for auditory abnormalities at a younger age than control subjects. Auditory evaluation of vitiligo patients should be considered for early detection of hearing loss.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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