拉瓦尔品第类风湿关节炎患者健康相关生活质量评估：一项横断面研究

IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2025-07-28 DOI:10.1016/j.cegh.2025.102151

Muhammad Amer , Saleh Ahmed , Muhammad Akhlaq , Hoorain Bibi , Ishmal , Muhammad Ishfaq , Muhammad Nouman Arshad , Simrah Rehman Malik , Ali Ahmed

{"title":"拉瓦尔品第类风湿关节炎患者健康相关生活质量评估：一项横断面研究","authors":"Muhammad Amer , Saleh Ahmed , Muhammad Akhlaq , Hoorain Bibi , Ishmal , Muhammad Ishfaq , Muhammad Nouman Arshad , Simrah Rehman Malik , Ali Ahmed","doi":"10.1016/j.cegh.2025.102151","DOIUrl":null,"url":null,"abstract":"<div><h3>Background/objectives</h3><div>Rheumatoid arthritis (RA) is a chronic inflammatory disorder that significantly impairs patients' health-related quality of life (HRQoL). Early diagnosis and improved disease management can alleviate a patient and country's financial burden. The study aimed to evaluate the HRQoL of RA patients in Rawalpindi to highlight its debilitating nature in the national context.</div></div><div><h3>Methods</h3><div>This cross-sectional study evaluates the HRQoL of RA patients in Rawalpindi using the EuroQol 5D (EQ-5D) scale. The study involved 400 participants from the outpatient department of Benazir Bhutto Hospital, primarily middle-aged women, assessing various domains of health, including mobility, self-care, usual activities, pain, and depression.</div></div><div><h3>Results</h3><div>A significant decrease in HRQoL was observed in RA patients, influenced by the duration and severity of the disease (p-value = 0.00). The mean EQ-5D index score was 0.4 ± 0.4, while the mean VAS score was 54.7 ± 16.5. Most participants (43 %) experienced moderate disease intensity, with diabetes (27.8 %) and high blood pressure (20 %) being common comorbidities. Pain and physical impairments significantly impacted daily activities and emotional well-being, with 23.5 % of patients reporting moderate problems in multiple dimensions of the EQ-5D scale.</div></div><div><h3>Conclusion</h3><div>RA has a profound impact on the HRQoL of patients in Rawalpindi. The effect is significantly associated with disease severity and duration, highlighting the need for comprehensive management strategies like early disease diagnosis and prompt treatment to improve the quality of life for RA patients.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"35 ","pages":"Article 102151"},"PeriodicalIF":1.7000,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Assessment of health-related quality of life among patients of rheumatoid arthritis in Rawalpindi: A cross-sectional study\",\"authors\":\"Muhammad Amer , Saleh Ahmed , Muhammad Akhlaq , Hoorain Bibi , Ishmal , Muhammad Ishfaq , Muhammad Nouman Arshad , Simrah Rehman Malik , Ali Ahmed\",\"doi\":\"10.1016/j.cegh.2025.102151\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background/objectives</h3><div>Rheumatoid arthritis (RA) is a chronic inflammatory disorder that significantly impairs patients' health-related quality of life (HRQoL). Early diagnosis and improved disease management can alleviate a patient and country's financial burden. The study aimed to evaluate the HRQoL of RA patients in Rawalpindi to highlight its debilitating nature in the national context.</div></div><div><h3>Methods</h3><div>This cross-sectional study evaluates the HRQoL of RA patients in Rawalpindi using the EuroQol 5D (EQ-5D) scale. The study involved 400 participants from the outpatient department of Benazir Bhutto Hospital, primarily middle-aged women, assessing various domains of health, including mobility, self-care, usual activities, pain, and depression.</div></div><div><h3>Results</h3><div>A significant decrease in HRQoL was observed in RA patients, influenced by the duration and severity of the disease (p-value = 0.00). The mean EQ-5D index score was 0.4 ± 0.4, while the mean VAS score was 54.7 ± 16.5. Most participants (43 %) experienced moderate disease intensity, with diabetes (27.8 %) and high blood pressure (20 %) being common comorbidities. Pain and physical impairments significantly impacted daily activities and emotional well-being, with 23.5 % of patients reporting moderate problems in multiple dimensions of the EQ-5D scale.</div></div><div><h3>Conclusion</h3><div>RA has a profound impact on the HRQoL of patients in Rawalpindi. The effect is significantly associated with disease severity and duration, highlighting the need for comprehensive management strategies like early disease diagnosis and prompt treatment to improve the quality of life for RA patients.</div></div>\",\"PeriodicalId\":46404,\"journal\":{\"name\":\"Clinical Epidemiology and Global Health\",\"volume\":\"35 \",\"pages\":\"Article 102151\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-07-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Epidemiology and Global Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2213398425002404\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Epidemiology and Global Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213398425002404","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}

引用次数: 0

摘要

背景/目的类风湿关节炎（RA）是一种慢性炎症性疾病，严重影响患者健康相关生活质量（HRQoL）。早期诊断和改善疾病管理可以减轻患者和国家的经济负担。该研究旨在评估拉瓦尔品第RA患者的HRQoL，以突出其在全国范围内的衰弱性。方法采用EuroQol 5D （EQ-5D）量表评估拉瓦尔品第地区RA患者的HRQoL。这项研究涉及贝娜齐尔·布托医院门诊部的400名参与者，主要是中年妇女，评估健康的各个领域，包括行动能力、自我保健、日常活动、疼痛和抑郁。结果RA患者HRQoL明显下降，受病程和病情严重程度的影响（p值= 0.00）。平均EQ-5D评分为0.4±0.4，平均VAS评分为54.7±16.5。大多数参与者（43%）经历中度疾病强度，糖尿病（27.8%）和高血压（20%）是常见的合并症。疼痛和身体损伤显著影响日常活动和情绪健康，23.5%的患者报告在EQ-5D量表的多个维度中存在中度问题。结论ra对拉瓦尔品第患者的HRQoL有深远的影响。该效应与疾病严重程度和持续时间显著相关，强调需要综合管理策略，如早期疾病诊断和及时治疗，以改善RA患者的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Assessment of health-related quality of life among patients of rheumatoid arthritis in Rawalpindi: A cross-sectional study

Background/objectives

Rheumatoid arthritis (RA) is a chronic inflammatory disorder that significantly impairs patients' health-related quality of life (HRQoL). Early diagnosis and improved disease management can alleviate a patient and country's financial burden. The study aimed to evaluate the HRQoL of RA patients in Rawalpindi to highlight its debilitating nature in the national context.

Methods

This cross-sectional study evaluates the HRQoL of RA patients in Rawalpindi using the EuroQol 5D (EQ-5D) scale. The study involved 400 participants from the outpatient department of Benazir Bhutto Hospital, primarily middle-aged women, assessing various domains of health, including mobility, self-care, usual activities, pain, and depression.

Results

A significant decrease in HRQoL was observed in RA patients, influenced by the duration and severity of the disease (p-value = 0.00). The mean EQ-5D index score was 0.4 ± 0.4, while the mean VAS score was 54.7 ± 16.5. Most participants (43 %) experienced moderate disease intensity, with diabetes (27.8 %) and high blood pressure (20 %) being common comorbidities. Pain and physical impairments significantly impacted daily activities and emotional well-being, with 23.5 % of patients reporting moderate problems in multiple dimensions of the EQ-5D scale.

Conclusion

RA has a profound impact on the HRQoL of patients in Rawalpindi. The effect is significantly associated with disease severity and duration, highlighting the need for comprehensive management strategies like early disease diagnosis and prompt treatment to improve the quality of life for RA patients.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.