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Association of brown-fat-secreted adipokine neuregulin 4 with gestational diabetes mellitus: A systematic review and meta-analysis
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2024.101908
Roshan Kumar Mahat , Vedika Rathore , Manisha Arora , Rahul Mishra , Sudeep Kumar
{"title":"Association of brown-fat-secreted adipokine neuregulin 4 with gestational diabetes mellitus: A systematic review and meta-analysis","authors":"Roshan Kumar Mahat ,&nbsp;Vedika Rathore ,&nbsp;Manisha Arora ,&nbsp;Rahul Mishra ,&nbsp;Sudeep Kumar","doi":"10.1016/j.cegh.2024.101908","DOIUrl":"10.1016/j.cegh.2024.101908","url":null,"abstract":"<div><h3>Aim</h3><div>Neuregulin-4, a newly identified adipokine, is thought to play a role in the regulation of energy balance and glycolipid metabolism. This meta-analysis aimed to investigate the association between Neuregulin-4 (Nrg4) and gestational diabetes mellitus (GDM).</div></div><div><h3>Methods</h3><div>A comprehensive search was conducted across four electronic databases- PubMed (Medline), Scopus, Europe PMC, and Google Scholar to identify relevant studies published up until August 2, 2024. A random effects model was utilized to compute the standardized mean difference (SMD) and 95 % confidence interval (CI). Statistical heterogeneity was assessed using Cochran's Q test, the I<sup>2</sup> statistic, and prediction intervals (PI). Additionally, a meta-correlation analysis was performed to explore the relationship between Nrg4 and various biochemical parameters.</div></div><div><h3>Results</h3><div>This meta-analysis incorporated seven studies comprising 347 subjects with GDM and 362 subjects without GDM. No significant difference was observed in circulating Nrg4 levels between the GDM and non-GDM groups (SMD = −0.35, 95 % CI = −1.17 to 0.48, p = 0.41, I<sup>2</sup> = 96 %). The 95 % prediction interval ranged from −3.35 to 2.66. Sensitivity analysis and subgroup analysis by sample size, continent, and study design reported significantly reduced levels of Nrg4 in GDM compared to non-GDM. The meta-correlation analysis revealed that Nrg4 was not significantly correlated with most biochemical and metabolic parameters studied in GDM. However, sensitivity analyses in certain instances suggested potential associations after the exclusion of specific studies.</div></div><div><h3>Conclusion</h3><div>Sensitivity analysis and subgroup analysis by sample size, continent, and study design reported significantly reduced levels of Nrg4 in GDM compared to non-GDM, suggesting a possible protective function of Nrg4 in GDM.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101908"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An interrupted time series analysis to assess the impact of implementing the clinical audit process for stillbirths and neonatal deaths in Morocco
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2024.101898
Mina EL Hiyani , Othmane Benlenda , Asmaa Mdaghri Alaoui , Redouane Abouqal , Amal Thimou Izgua
{"title":"An interrupted time series analysis to assess the impact of implementing the clinical audit process for stillbirths and neonatal deaths in Morocco","authors":"Mina EL Hiyani ,&nbsp;Othmane Benlenda ,&nbsp;Asmaa Mdaghri Alaoui ,&nbsp;Redouane Abouqal ,&nbsp;Amal Thimou Izgua","doi":"10.1016/j.cegh.2024.101898","DOIUrl":"10.1016/j.cegh.2024.101898","url":null,"abstract":"<div><h3>Objectives</h3><div>This article aims to evaluate the clinical audit process for stillbirths and neonatal deaths and its impact on reducing neonatal mortality at the Hassan I Hospital, Tiznit, Morocco. This process was initially implemented in Morocco in 2017.</div></div><div><h3>Methods</h3><div>The clinical audit process was evaluated using a semi-structured interview with the managers monitoring the clinical audit of stillbirths and neonatal deaths. The impact of the clinical audit on reducing neonatal mortality rates was assessed by analysing neonatal mortality rates using interrupted time series analysis (ITSA).</div></div><div><h3>Results</h3><div>A study of the interrupted time series showed that there was a slight downward trend in the monthly neonatal mortality rate before implementation of the clinical audit (estimate - 0.20, CI 95 %: 0.23–0.16, P &lt; 0.001) with a very significant drop just at the time of performance of the clinical audit (assessment - 11, CI 95 %: 15.1–8.87, P &lt; 0.001)The monthly neonatal mortality rates recorded, which are similar to the recommended international standards, stabilised after the clinical audit was implemented (estimate 0.16, CI 95 %:0.11–0.21, P &lt; 0.001) with an improvement in the care of newborns through the availability of human resources, materials and equipment.</div></div><div><h3>Conclusion</h3><div>The audit of stillbirths and neonatal deaths reduced neonatal mortality by improving the mother-newborn couple's management quality. In addition, the study highlighted the need to introduce several community participation mechanisms that could be adapted and piloted to establish a more comprehensive and effective audit practice.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101898"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and validation of android mobile application in the management of mental health
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2024.101894
G. Hari Prakash , D. Sunil Kumar , Vanishri Arun , Deepika Yadav , Arun Gopi , Rishi Garg
{"title":"Development and validation of android mobile application in the management of mental health","authors":"G. Hari Prakash ,&nbsp;D. Sunil Kumar ,&nbsp;Vanishri Arun ,&nbsp;Deepika Yadav ,&nbsp;Arun Gopi ,&nbsp;Rishi Garg","doi":"10.1016/j.cegh.2024.101894","DOIUrl":"10.1016/j.cegh.2024.101894","url":null,"abstract":"<div><h3>Background</h3><div>The critical window of adolescence demands accessible and effective interventions to address mental health needs. This study aimed to develop and validate a mobile application to promote adolescents' mental well-being.</div></div><div><h3>Methods</h3><div>The Android app was developed using a user-centred approach focused on engaging the target audience of adolescents. A quasi-experimental study was conducted with 60 adolescent participants assigned to the experimental (app users) or control group. Satisfaction with the app and mental health outcomes were assessed at baseline and after app usage.</div></div><div><h3>Results</h3><div>At baseline, participants struggled to answer very simple questions about their mental health concerns. After using the app, participants' satisfaction was significantly higher in the experimental group compared to the control group. At follow-up, participants struggled to comprehensively answer complex and open-ended questions about their experience using the app. Their code transcribed from the app effectively captured their mental health concerns.</div></div><div><h3>Conclusion</h3><div>The app-enabled participants to express their thoughts concisely through code transcribed from their mental health concerns. Despite participants' struggles with complex questioning, the app's contents addressed their needs through transcribed code. The app engaged users effectively by allowing code from their mental health concerns to be the content.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101894"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143163376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-care practices on hypertension: Prevalence and predictors in Puducherry, South India
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2024.101883
Chandru Sivamani , Ganesh Kumar Saya , Revathi Ulaganeethi , Palanivel Chinnakali
{"title":"Self-care practices on hypertension: Prevalence and predictors in Puducherry, South India","authors":"Chandru Sivamani ,&nbsp;Ganesh Kumar Saya ,&nbsp;Revathi Ulaganeethi ,&nbsp;Palanivel Chinnakali","doi":"10.1016/j.cegh.2024.101883","DOIUrl":"10.1016/j.cegh.2024.101883","url":null,"abstract":"<div><h3>Background</h3><div>Self-care practices plays an important role in reducing the mortality and morbidity associated with hypertensive complications. Therefore, this study aimed to assess poor self-care practices on hypertension and its predictors among patients attending the non-communicable disease clinics in urban and rural primary healthcare settings in Puducherry, South India.</div></div><div><h3>Methods</h3><div>A cross-sectional analytical study was conducted among people with hypertension aged ≥18 years from September to December 2023. Systematic random sampling technique was used to recruit the participants. The data on self-care practices were captured using the “Hypertension Self-Care Activity Level Effects (H-SCALE)” questionnaire. The subscales were medication adherence, low-salt diet, physical activity, smoking, alcohol and weight management. Participants who adhered &lt;4 out of six subscales of H-SCALE, was considered as poor self-care practices. Multivariable analysis was carried out to adjust for potential covariates, and adjusted prevalence ratio with a 95 % confidence interval was reported.</div></div><div><h3>Results</h3><div>Out of 267 participants with hypertension, 158 (59.2 %) were &gt;60 years of age and 182 (68.2 %) were females. About 79 (29.6 %) had poor self-care practices. Among 267, 63 (23.6 %) had uncontrolled hypertension and it was more among those with poor self-care practices (46.1 % Vs 24.5 %). After adjusting for co-variates, urban residents (APR: 1.7, 95 % CI: 1.1–2.4, p = 0.004) and uncontrolled hypertension status (APR: 1.8, 95 % CI: 1.1–2.4, p &lt; 0.001) were significantly associated with poor self-care practices.</div></div><div><h3>Conclusion</h3><div>More than one-fourth of the participants with hypertension had poor self-care practices and it was significantly higher in participants with uncontrolled hypertension.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101883"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L-shaped relationship of Vitamin D and blood lead levels among preschool children age 3–6: A cross-sectional study
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2024.101864
Shengying Zhang, Bibo Mao, Fei Xu, Chenbo Zhou, Wenyuan Liu
{"title":"L-shaped relationship of Vitamin D and blood lead levels among preschool children age 3–6: A cross-sectional study","authors":"Shengying Zhang,&nbsp;Bibo Mao,&nbsp;Fei Xu,&nbsp;Chenbo Zhou,&nbsp;Wenyuan Liu","doi":"10.1016/j.cegh.2024.101864","DOIUrl":"10.1016/j.cegh.2024.101864","url":null,"abstract":"<div><h3>Background</h3><div>Childhood lead exposure negatively impacts health, and its link to Vitamin D levels in preschoolers is not well understood.</div></div><div><h3>Objective</h3><div>To investigate the association between Vitamin D and blood lead levels (BLLs) in Chinese preschool children aged 3-6.</div></div><div><h3>Methods</h3><div>A cross-sectional study of 604 children from three Ningbo kindergartens in 2019 measured serum Vitamin D using Chemiluminescence Immunoassay and BLLs via ICP-MS. We used multivariate linear regression, adjusting for factors like age, gender, BMI, hemoglobin, family income, parental occupations, and residential location, and smooth curve fitting to analyze the dose-response relationship.</div></div><div><h3>Results</h3><div>The average age was 5.4 ± 0.8 years, with BLLs at 19.7 ± 12.1 µg/L. Each 1 ng/mL increase in Vitamin D correlated with a 0.29 µg/L decrease in BLLs (95% CI: -0.43 to -0.16, p &lt; 0.001). The inverse association was significant in males and suburban residents. A threshold effect was identified at 38.679 ng/mL Vitamin D, beyond which BLLs did not decrease further (β = -0.506, 95% CI: -0.777 to -0.235, p &lt;0.001).</div></div><div><h3>Conclusions</h3><div>Higher Vitamin D levels are significantly linked to lower BLLs, especially in males and suburban residents, with a threshold at 38.679 ng/mL. Above this, no further BLL reduction is observed, highlighting the importance of optimal Vitamin D levels in mitigating lead exposure.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101864"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor: “A study on socio-demographic-based knowledge and awareness for cervical cancer among women from Uttar Pradesh, India”
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2024.101891
Kushal Krishna Banerjee, Rabia Batool Hussain
{"title":"Letter to the Editor: “A study on socio-demographic-based knowledge and awareness for cervical cancer among women from Uttar Pradesh, India”","authors":"Kushal Krishna Banerjee,&nbsp;Rabia Batool Hussain","doi":"10.1016/j.cegh.2024.101891","DOIUrl":"10.1016/j.cegh.2024.101891","url":null,"abstract":"","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101891"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of prurigo nodularis: An analysis of global trends from 1998–2023
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2024.101906
Shiyan Yang , Chunxiao Wang , Sihan Wang , Yuanting Yu , Xiaoce Cai , Yifei Wang , Xin Li
{"title":"Epidemiology of prurigo nodularis: An analysis of global trends from 1998–2023","authors":"Shiyan Yang ,&nbsp;Chunxiao Wang ,&nbsp;Sihan Wang ,&nbsp;Yuanting Yu ,&nbsp;Xiaoce Cai ,&nbsp;Yifei Wang ,&nbsp;Xin Li","doi":"10.1016/j.cegh.2024.101906","DOIUrl":"10.1016/j.cegh.2024.101906","url":null,"abstract":"","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101906"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ten-year Atherosclerosis Cardiovascular Disease (ASCVD) risk score and its components among nomadic population in southern Iran: A population-based study
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2025.101913
Fariba Moradi Ardekani , Mohammad Javad Zibaeenezhad , Mehrab Sayadi , Fatemeh Jafari , Shirzad Javidi AL-e-Saadi , Hamed Karami , Aboubakr Jafarnezhad , Sina Rokhsari , Ahad Amiri Gharghani
{"title":"Ten-year Atherosclerosis Cardiovascular Disease (ASCVD) risk score and its components among nomadic population in southern Iran: A population-based study","authors":"Fariba Moradi Ardekani ,&nbsp;Mohammad Javad Zibaeenezhad ,&nbsp;Mehrab Sayadi ,&nbsp;Fatemeh Jafari ,&nbsp;Shirzad Javidi AL-e-Saadi ,&nbsp;Hamed Karami ,&nbsp;Aboubakr Jafarnezhad ,&nbsp;Sina Rokhsari ,&nbsp;Ahad Amiri Gharghani","doi":"10.1016/j.cegh.2025.101913","DOIUrl":"10.1016/j.cegh.2025.101913","url":null,"abstract":"<div><h3>Introduction</h3><div>Prevalence of atherosclerotic cardiovascular disease (ASCVD) has increased in developing countries, such as Iran. For reducing ASCVD, epidemiological information, especially in nomadic populations, are needed. This study aimed to estimate the prevalence of ASCVD among the nomadic population.</div></div><div><h3>Method</h3><div>This cross-sectional study was conducted on 784 nomadic people aged 40–70 years in Fars province. The 10-year ASCVD risk was calculated with an estimator developed by the American College of Cardiology/American Heart Association (ACC/AHA). To determine the factors of ASCVD risk score, ordinal logistic regression was used. Statistical analyses were performed using SPSS version 16 software.</div></div><div><h3>Results</h3><div>The mean age of the subjects under study was 53.32 ± 8.94 years, of whom 432 (55.1 %) were female. Based on ordinal regression, access to the health centers (p = 0.002), diabetes (p &lt; 0.001), MI (p = 0.023), not using Aspirin (p = 0.001), housekeeper job (p &lt; 0.001), high LDL (p = 0.002), and physical activity (p = 0.04) were associated with a higher category of ASCVD risk score. Additionally, people in the age group of 60–69 years had the highest percentage in all ASCVD score classes except the low-risk group.</div></div><div><h3>Conclusion</h3><div>The results indicated that having modifiable risk factors increases the chance of CVD in the nomadic population, and older people are more at risk. Since this population has received less attention and plays a main role in providing food products for Iranian people, it is suggested that more attention should be paid to the health of this special group through prevention and control programs.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101913"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and factors associated with cognitive impairment among persons with type 2 diabetes mellitus: A cross-sectional study in medical college hospitals of South India
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2024.101887
Pracheth Raghuveer , Manaal Shamsudeen , Shipra Sridhar , Riya Singla , Vaibhav Gupta , Namit Mittal , Diva Bhandari , Mithun Rao
{"title":"Prevalence and factors associated with cognitive impairment among persons with type 2 diabetes mellitus: A cross-sectional study in medical college hospitals of South India","authors":"Pracheth Raghuveer ,&nbsp;Manaal Shamsudeen ,&nbsp;Shipra Sridhar ,&nbsp;Riya Singla ,&nbsp;Vaibhav Gupta ,&nbsp;Namit Mittal ,&nbsp;Diva Bhandari ,&nbsp;Mithun Rao","doi":"10.1016/j.cegh.2024.101887","DOIUrl":"10.1016/j.cegh.2024.101887","url":null,"abstract":"<div><h3>Background</h3><div>The increased prevalence of diabetes is of a major concern in the background of a developing country like India with tremendous population. Diabetes Mellitus type 2 leads to complications if not diagnosed early and started on treatment. Adding to this, persons with Type 2 Diabetes Mellitus (T2DM) are also vulnerable to develop cognitive impairment and affects many cognitive domains. Therefore, recognition of cognitive disorders among diabetic persons with T2DM are important.</div></div><div><h3>Method</h3><div>ology: This is a cross sectional study done in persons with T2DM attending two tertiary care teaching hospitals. There were a total of 108 study participants aged ≥18 years and the study was done for one month. Cognitive screening was carried out using Montreal Cognitive Assessment (MoCA) and a score of ≥26 out of 30 was considered as normal cognitive function.</div></div><div><h3>Results</h3><div>It was observed that 45 (41.70 %) of the participants had cognitive impairment and it was found to be higher among persons aged ≥60 years, 27 (75.0 %) when compared to age &lt;60 years, 36 (50.0 %). This association was found to be statistically significant (p = 0.02). Of the 58 participants who had diabetes for &gt;7years, 41 (70.70 %), had cognitive impairment while 17 (29.30 %) did not have (p &lt; 0.01). Cognitive impairment was found to be significantly higher among participants with hypertension (74.20 %) when compared to those without hypertension (59.70 %).</div></div><div><h3>Conclusion</h3><div>Prevalence of cognitive impairment in persons with T2DM was found out to be 58.30 %. Duration of diabetes ≥7 years was found to be the significant factor associated with cognitive impairment in our research.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101887"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vision-related Quality of Life (VRQOL) and its determinants among the Elderly in rural blocks of Haryana, India
IF 2.3
Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI: 10.1016/j.cegh.2024.101865
Mona Duggal , Ankita Kankaria , Latika Rohilla , Harashish Jindal , Limalemla Jamir , Parul Chawla Gupta , Debarati Sarkar , Vaibhav Miglani , Akash Kumar , Drishti Sharma , Neha Dahiya , Siddhartha Sharma , Sandeep Grover
{"title":"Vision-related Quality of Life (VRQOL) and its determinants among the Elderly in rural blocks of Haryana, India","authors":"Mona Duggal ,&nbsp;Ankita Kankaria ,&nbsp;Latika Rohilla ,&nbsp;Harashish Jindal ,&nbsp;Limalemla Jamir ,&nbsp;Parul Chawla Gupta ,&nbsp;Debarati Sarkar ,&nbsp;Vaibhav Miglani ,&nbsp;Akash Kumar ,&nbsp;Drishti Sharma ,&nbsp;Neha Dahiya ,&nbsp;Siddhartha Sharma ,&nbsp;Sandeep Grover","doi":"10.1016/j.cegh.2024.101865","DOIUrl":"10.1016/j.cegh.2024.101865","url":null,"abstract":"<div><h3>Background</h3><div>Vision related quality of life (VRQOL) measures one's satisfaction with their visual ability to perform daily activities. Aging leads to vision impairment that can negatively affect VRQOL and physical, psychological, and social well-being.</div></div><div><h3>Objective</h3><div>To assess vision-related quality of life (VR-QOL) and its determinants among elderly residents from rural blocks of Haryana, India.</div></div><div><h3>Method</h3><div>This cross-sectional study was performed across 52 Indian villages. The vision-related quality of life scores was assessed using National Eye Institute Vision Function Questionnaire-25(VFQ-25). Social Connectedness, Geriatric Depression Scale, Mini-Mental Status Examination, and the Katz Index of Independence were collected using validated tools. Continuous data was represented as Mean (±SD) or median (IQR) depending upon their distribution. Categorical data as frequency (%). Bivariate analysis was done using Student t-test or Rank Sum test for continuous variables (for up to 2 groups) and One-Way ANOVA was run for continuous variables (for more than 2 groups). Chi-Sq. test or Fisher's for categorical variables and multivariable linear regression model was run to calculate the determinants of the VFQ composite score.</div></div><div><h3>Result</h3><div>Amongst the 420 participants, 58 % were females and 74 % were illiterates. The mean VR-QOL was 42.30 ± 11.19 in the study population. The study found higher VR-QOL scores in <em>General Health, Distance activities,</em> and <em>Near activities</em>, while lower scores were observed in <em>Mental health, Dependency, Social functioning, Ocular pain, General vision</em>, and <em>Role difficulties</em>. Both the mean VR-QOL composite score and the VR-QOL domains of <em>General Health, General Vision, Ocular Pain, Role Difficulties, Mental Health,</em> and <em>Dependence</em> were all greater for women than for men. Among the reported morbidities 26 % had hearing loss, 23 % were hypertensives, 9 % were diabetics, 85 % were dependent, 60 % had depression, 14 % had moderate dementia, 10 % had lower tendency to connect, 8 % had low vision and 35 % had vertigo. VFQ scores were lower among males, non-Hindus, hypertensives and among person with history of vertigo and those living in dim light than their counterparts.</div></div><div><h3>Conclusion</h3><div>The current study shows that VR-QOL is significantly lower in male, participants with history of vertigo, hypertension, diabetes and who live in dim light. There is a need to develop strategies to address these determinants through multidisciplinary approach including chronic disease management and environmental modification and promote healthy aging of elderly population.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"31 ","pages":"Article 101865"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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