Clinical Epidemiology and Global Health最新文献

{"title":"Mortality and clinical outcomes of ceftazidime/avibactam vs best available therapy in treating carbapenem-resistant enterobacterales infections: A retrospective cohort study","authors":"Nada Alhamed ,&nbsp;Mai Hashhoush ,&nbsp;Raghad Al-Omari ,&nbsp;Marwa Alomani ,&nbsp;Reem S. AlOmar","doi":"10.1016/j.cegh.2025.102061","DOIUrl":"10.1016/j.cegh.2025.102061","url":null,"abstract":"<div><h3>Objective</h3><div>The epidemiology of infectious diseases shows that antimicrobial resistance (AMR) is a global health issue. This study aimed to compare 14-day mortality in patients with confirmed Carbapenem-resistant Enterobacterales (CRE) infections treated with Ceftazidime/Avibactam (CAZ-AVI) to the best available therapies (BAT) in the Kingdom of Saudi Arabia where there is a predominance of the OXA-48 gene.</div></div><div><h3>Methods</h3><div>This retrospective cohort study included adult patients with confirmed CRE infections treated with CAZ-AVI or BAT between 2018 and 2021. The Cox proportional hazards model was applied to derive both unadjusted and adjusted hazard ratios for 14-days and 30-day mortality. Bivariate analyses included chi-squared tests for categorical data, t-tests and Mann-Whitney tests for continuous data.</div></div><div><h3>Results</h3><div>The study included 157 patients; of those, 88 (56 %) were males, 63 (40.1 %) had malignancy, and the mean age was 54.85 years. Seventy (44.59 %) received CAZ-AVI. Bacteraemia (28 %) and urinary tract infections (27.3 %) were the most common sources. Klebsiella pneumonia (126, 80.25 %) was the predominant pathogen, with OXA-48 gene identified in 35.67 % of cases. The risk of 14-day mortality for patients treated with Ceftazidime/Avibactam was significantly lower compared to patients treated with the best available therapies (adjusted HR = 0.45, 95 % CI = 0.22–0.92).</div></div><div><h3>Conclusion</h3><div>CRE represents a global threat and is associated with high mortality and morbidity. Ceftazidime/Avibactam was associated with a lower risk of 14-day mortality in patients treated for CRE infections. Larger-scale prospective trials to confirm the outcomes of this study are needed.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102061"},"PeriodicalIF":2.3,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143942634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-related quality of life of patients with rifampicin-resistant/multidrug-resistant tuberculosis in Vietnam: a prospective follow-up study","authors":"Nguyen Vu Anh Thu ,&nbsp;Cao Nguyen Hoai Thuong ,&nbsp;Trinh Hoang Duy ,&nbsp;Ngo Thi Thuy Dung","doi":"10.1016/j.cegh.2025.102054","DOIUrl":"10.1016/j.cegh.2025.102054","url":null,"abstract":"<div><h3>Background</h3><div>Currently, the management of rifampicin-resistant/multidrug-resistant tuberculosis (RR/MDR-TB) primarily focuses on clinical characteristics and microbiological indicators. However, the disease also negatively impacts patients' psychological, economic, and social well-being. Thus, shifting our attention toward health-related quality of life (HRQOL) is essential.</div></div><div><h3>Method</h3><div>This was a prospective follow-up study conducted within government programmatic management of drug-resistant tuberculosis clinics in seven provinces of Vietnam. HRQOL was assessed at the baseline and after six months of treatment using the SF-36 version 2.0 questionnaire.</div></div><div><h3>Result</h3><div>A total of 180 patients with RR/MDR-TB completed the SF-36 version 2.0 survey at two time points. The physical component summary (PCS) scores at these two time points were 42.0 ± 8.4 and 44.2 ± 10.5, while the mental component summary (MCS) scores were 41.7 ± 9.0 and 49.8 ± 11.4, respectively. Following multivariable analysis, educational level and marital status were found to be associated with changes in PCS scores from baseline to six months of treatment. Conversely, age, comorbidity, and tuberculosis treatment category were related to changes in MCS scores.</div></div><div><h3>Conclusion</h3><div>Treatment for RR/MDR-TB has a positive impact on the HRQOL of patients. However, the PCS score after six months of treatment remained low. Therefore, incorporating appropriate exercise regimens, physical therapy measures, and rehabilitation strategies tailored to the needs and capabilities of each patient is essential to enhance their physical health.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102054"},"PeriodicalIF":2.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interconnections of physical activity, cognition, functional health and social connectivity with perceived happiness among rural adults: Population based study","authors":"AmitaSamal,&nbsp;Varalakshmi Manchana","doi":"10.1016/j.cegh.2025.102056","DOIUrl":"10.1016/j.cegh.2025.102056","url":null,"abstract":"<div><h3>Background</h3><div>Successful aging, within the context of a life course approach, emphasizes the direct proportionality of happiness with physical, cognitive, mental, and social well-being. Subjective well-being is a robust predictor of the overall health and functioning of individuals. The current study examines the association of happiness with physical activity, cognition, social connectivity, and functional health in middle and old-age populations from rural communities.</div></div><div><h3>Method</h3><div>A cross-sectional design was applied to collect data among 270 adults (40–90years), under the purview of Patancheru rural health center on happiness (Oxford Happiness Questionnaire-OHQ), physical activity (International Physical Activity Questionnaire-IPAQ), Cognition (Montreal Cognitive Assessment-MoCA), Social connectivity (Duke Social Support Index-DSSI) and overall functional health by using standard tools. Association was measure using chi-square test of independence and Spearman's correlation was used and results were derived at a 95 % confidence interval with a significance level set at 0.5, 0.01, and 0.001.</div></div><div><h3>Results</h3><div>Findings of the study highlight a positive association between socio-demographic variables such as age, education, marital status, occupation, and income with happiness. Cognition was a strong correlate of happiness (0.473) followed by physical activity (PA) (0.2195) while social connectivity showed a weaker association (0.0469).</div></div><div><h3>Conclusion</h3><div>Outcomes of the study indicates an overall positive relationship of happiness with multidimensional components of health and wellbeing in aging population. Promoting physical and cognitive interventions, integrating social component from midlife will be a sustainable approach to promote healthy and active aging in aging population in general and in rural adults in specific for sustainable and healthy societies.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102056"},"PeriodicalIF":2.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143947018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and enablers of using a clinical decision support algorithm to consult sick children at primary health facilities: A qualitative study from Uttar Pradesh, India","authors":"Mansi Tyagi ,&nbsp;Divas Kumar ,&nbsp;Kovid Sharma ,&nbsp;Fenella Beynon ,&nbsp;Gaurav Kumar ,&nbsp;Hélène Langet ,&nbsp;Gillian A. Levine ,&nbsp;Michael A. Ruffo ,&nbsp;Mira Emmanuel Fabula ,&nbsp;Valérie D'Acremont ,&nbsp;Kaspar Wyss ,&nbsp;Leah F. Bohle ,&nbsp;Shally Awasthi","doi":"10.1016/j.cegh.2025.102038","DOIUrl":"10.1016/j.cegh.2025.102038","url":null,"abstract":"<div><h3>Introduction</h3><div>In Indian public health system, adherence to Integrated Management of Childhood Illness (IMNCI) guidelines is low due to inadequate capacity building, high workload and shortage of healthcare providers (HCPs). Objective was to explore barriers and enablers experienced by HCPs using a digital clinical decision support algorithm (CDSA) for consultation of sick under-five children at primary healthcare facilities in Uttar Pradesh, India.</div></div><div><h3>Method</h3><div>From nine facilities, ten HCPs were trained on IMNCI guidelines and CDSA use. In-depth interviews (IDIs) of HCPs were conducted at three weeks (early phase) and five months (late phase), after intervention initiation.</div></div><div><h3>Result</h3><div>From July-to-December 2022, nine IDIs were conducted in early and eight in late phase. One HCP was paediatrician, five were trained in modern medicine and remaining in Indian traditional medicine systems. Their median clinical experience was 11 years. High patient load, HCP's shortage, multiple responsibilities and lack of supervisory support were identified as facility related barriers to CDSA implementation. Additionally, software glitches, substantial time requirements to complete consultation with CDSA and manual data entry were identified as device-related barriers. Low patient load, perceived value of CDSA by HCPs and ability of CDSA to work offline were identified as enablers. From early to late phase, no strong differences were identified on views about CDSA, with some of the barriers however being stronger.</div></div><div><h3>Conclusion</h3><div>CDSA can enhance access to evidence-based guidelines and improve awareness of assessment and management, as highlighted by HCPs. To fully realize these benefits, system challenges and technological barriers must be addressed.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"34 ","pages":"Article 102038"},"PeriodicalIF":2.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144084604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of ST-segment elevation acute coronary syndromes in the emergency department of Gabes","authors":"Samet Amal ,&nbsp;Rahma Kallel ,&nbsp;Hichem Denguir ,&nbsp;Imene Rejeb","doi":"10.1016/j.cegh.2025.102005","DOIUrl":"10.1016/j.cegh.2025.102005","url":null,"abstract":"<div><h3>Introduction</h3><div>Acute coronary syndromes (ACS) are one of the leading causes of morbidity and mortality in Tunisia. Timely and effective management in the emergency department is crucial to improving patient outcomes, particularly in cases of ST-segment elevation myocardial infarction (STEMI).</div></div><div><h3>Objective</h3><div>To study the prognosis and management of acute coronary syndromes in the emergency department.</div></div><div><h3>Methods</h3><div>A retrospective, monocentric, cross-sectional, descriptive, and analytical study was conducted at the critical emergency unit of Mohamed Ben Sassi University Hospital in Gabes. The study covered a period from January 1, 2020, to December 31, 2022, lasting 36 months.</div></div><div><h3>Results</h3><div>The mean age of patients was 65.2 ± 13.52 years, with a male-to-female ratio of 3.08. Forty-eight percent of patients were from Gabes city. In 80 % of cases (n = 269), at least one comorbidity was observed, including diabetes (152 patients), hypertension (124 patients), and coronary artery disease (28 patients). Chest pain was the most common symptom, noted in 95.3 % of cases (n = 323). Only 33 patients (9.73 %) had first medical contact within 1 h. Antithrombotic therapy was administered to 97.34 % of patients, and morphine was used in 18 % of cases. Thrombolysis was performed in 36.3 % of cases, with a success rate of 82.9 %. Angioplasty was performed in 10.02 % of cases. Of the patients, 90.26 % were transferred to a coronary care unit (CCU), while 3.53 % were transferred to intensive care, and 6.19 % died.</div></div><div><h3>Conclusion</h3><div>Predictive factors for thrombolysis failure in the acute phase of STEMI are critical for improving emergency management strategies.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"33 ","pages":"Article 102005"},"PeriodicalIF":2.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants for migration among medical, dental and allied health sciences students- Unveiling brain drain","authors":"S. Vineetha ,&nbsp;Himani Kotian ,&nbsp;Rishit Anand","doi":"10.1016/j.cegh.2025.102051","DOIUrl":"10.1016/j.cegh.2025.102051","url":null,"abstract":"<div><h3>Introduction/objective</h3><div>\"Brain drain\" refers to the migration of healthcare professionals from low- and middle-income countries to higher-income countries. The study aims to understand the determinants influencing the migration of healthcare professionals, students' perceptions towards determinants of migration, to determine the proportion of students wanting to migrate and to associate socio-demographic characteristics of the study participants with the determinants responsible for professional migration.</div></div><div><h3>Methodology</h3><div>A cross-sectional study among 196 medical, dental, and allied health students in Mangaluru used a validated questionnaire. Data were collected via Microsoft Forms and analyzed in SPSS v29.0, with chi-square tests (p &lt; 0.05). Ethical approval and informed consent were obtained.</div></div><div><h3>Results</h3><div>The study found that 75 % of participants considered migrating abroad, with 52.1 % planning to take international exams. While 43.3 % intended to migrate for education and training, 40 % aimed for long-term career development. Key factors influencing migration included financial remuneration (36.3 %) and poor working conditions in India (38.1 %). A significant association was observed between students with close family abroad and migration plans (p &lt; 0.001), as well as those who actively discussed migration (p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The study highlights a strong inclination among medical, dental, and allied health students to migrate abroad, primarily for education, career growth, and better financial prospects. Poor working conditions and financial remuneration were key motivators. Close family abroad and discussions about migration significantly influenced migration decisions.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"33 ","pages":"Article 102051"},"PeriodicalIF":2.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between periodontitis and cognitive impairment in older adults: A cross-sectional study of the National Health and Nutrition Examination Survey","authors":"Qiyin Sun,&nbsp;Mianxiang Li","doi":"10.1016/j.cegh.2025.102020","DOIUrl":"10.1016/j.cegh.2025.102020","url":null,"abstract":"<div><h3>Objectives</h3><div>Periodontitis has been hypothesized as a modifiable risk factor for cognitive decline, yet population-based evidence remains limited. This study examined the relationship between periodontitis and cognitive impairment among the US seniors over 60.</div></div><div><h3>Methods</h3><div>This is a cross-sectional study based on the National Health and Nutrition Examination Survey (NHANES) 2011–2014. Periodontitis cases were identified and categorized as either none/mild or moderate/severe. Cognitive function was assessed using three questionnaire survey: the Consortium to Establish a Registry for Alzheimer's Disease Word Learning subtest (CERAD-WL), the Animal Fluency Test (AFT), and the Digit Symbol Substitution Test (DSST). Scores below the lowest quartile indicated cognitive impairment. A binary logistic regression was conducted to explore the relationship between periodontitis status and cognitive impairment in individuals over 60 years old.</div></div><div><h3>Results</h3><div>The findings indicated that 52.6 % of the sample (n = 2514) had moderate/severe periodontitis. In both CERAD-WL and DSST, the median score in the moderate/severe periodontitis cohort was high than that in the no/mild periodontitis cohort (<em>P</em> = .046,<em>P</em> = .010,respectively). Logistic regression model revealed an odds ratio of 1.605 (95 %CI: 1.407–1.898, <em>P</em> = .013) in DSST for the moderate/severe periodontitis group in unadjusted model, 1.288 (95 % CI:1.022–1.624, <em>P</em> = .032) in model 2 confounding demographic variables, and 1.290 (95 %CI: 1.021–1.630, <em>P</em> = .033) in model 3 confounding all covariants. Furthermore, the moderate/severe periodontitis is significantly associated with several factors: gender, the poverty income ratio(PIR) and dental visit frequency.</div></div><div><h3>Conclusion</h3><div>This study reveals a significant association between periodontitis and cognitive impairment among US seniors aged 60 and above in a nationally representative sample.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"33 ","pages":"Article 102020"},"PeriodicalIF":2.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144280428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiometabolic self-care and their determinants among older adults in India: evidence from the Longitudinal Ageing Study of India","authors":"Shubhanjali Roy ,&nbsp;Arka Ghosh ,&nbsp;Saurav Basu","doi":"10.1016/j.cegh.2025.102053","DOIUrl":"10.1016/j.cegh.2025.102053","url":null,"abstract":"<div><h3>Background</h3><div>Cardiometabolic syndrome (CMS) is a major public health issue in India, driven by urbanization, unhealthy dietary shifts, and sedentary lifestyles. Optimal cardiometabolic self-care, as defined by the Healthy Longevity Heart Code (HLHC), is critical to slowing cardiovascular aging and improving health outcomes.</div></div><div><h3>Objective</h3><div>To assess the prevalence and determinants of cardiometabolic self-care practices among older adults in India using HLHC proxies derived from the Longitudinal Ageing Study in India (LASI).</div></div><div><h3>Methods</h3><div>This study conducted a cross-sectional analysis of 66,606 participants aged ≥45 years from LASI (2017–2018). HLHC proxies included dietary habits, physical activity, waist circumference, smoking, alcohol consumption, sleep quality, mental exercises, and social interactions. Logistic regression analysis was used to identify predictors of optimal self-care, and mediation analysis assessed the role of wealth in modulating these outcomes.</div></div><div><h3>Results</h3><div>Only 34.3 % of participants exhibited optimal cardiometabolic self-care, with higher prevalence among females (40.04 %) compared to males (28.52 %). Predictors of optimal self-care included higher education, socioeconomic status, and urban residence. Wealth significantly mediated the relationship between socioeconomic factors and cardiometabolic health. Suboptimal practices such as high central obesity (64.13 % males; 41.59 % females) and poor mental and social engagement were prevalent. Tobacco use and alcohol consumption were notably higher among males, while females demonstrated better adherence to dietary and physical activity guidelines.</div></div><div><h3>Conclusions</h3><div>Suboptimal cardiometabolic self-care remains a significant challenge among Indian adults aged ≥45 years, with notable gender and socioeconomic disparities. Interventions should prioritize education, equitable access to resources, and gender-specific strategies to enhance adherence to HLHC guidelines and improve cardiometabolic health outcomes.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"33 ","pages":"Article 102053"},"PeriodicalIF":2.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143908228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public awareness about infant prematurity and its related health issues: A national-based survey in Jordan","authors":"Reem Ali ,&nbsp;Karimeh Alnuaimi ,&nbsp;Buthyna Alnasarat","doi":"10.1016/j.cegh.2025.102046","DOIUrl":"10.1016/j.cegh.2025.102046","url":null,"abstract":"<div><h3>Background</h3><div>The incidence of premature birth is high in Jordan, with no significant lowering of figures seen during the past decades. The knowledge of the associated high morbidity and mortality rate among preterm infants makes prematurity a high priority for the healthcare system in Jordan. This study aims to assess public awareness about prematurity, preterm infants’ health challenges and developmental disorders.</div></div><div><h3>Methods</h3><div>A national-based survey was employed to collected data on people's level of awareness. Online questionnaires were distributed across the country using proportional clusters protocol which was based on the geographical distribution of the population in Jordan.</div></div><div><h3>Results</h3><div>3048 Jordanians, aged from 18 to 77 years, completed the questionnaires; the majority of them were females and held married status. Results showed that 69.9 % of respondents gave a correct definition of prematurity. The average percentages of correct answers regarding the seriousness of prematurity, risks, and health and developmental problems were 71.5 %, 74.4 %, and 62.5 %, respectively. People generally failed to accurately identify premature infants’ long-term health and developmental problems. ANOVA results showed that the levels of awareness are significantly higher among people who have high family income (p &lt; 0.001), are well-educated (p &lt; 0.001), and employed in medical fields (p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>Educational initiatives are needed to enhance public awareness, particularly among the poor and less educated sectors of society. Lectures could be given by healthcare professionals at hospitals, and posted via social media, to educate people about prematurity and premature infants' health-related issues, with attention paid to infants’ long-term health and developmental problems.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"33 ","pages":"Article 102046"},"PeriodicalIF":2.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143886493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategic overview of rehabilitation practices and action plans for byssinosis: A holistic review","authors":"K. Vaishali ,&nbsp;Sarasa Meenakshi ,&nbsp;Mukesh Kumar Sinha ,&nbsp;Nitesh Kumar ,&nbsp;Revati Amin ,&nbsp;Krishna Murti","doi":"10.1016/j.cegh.2025.102050","DOIUrl":"10.1016/j.cegh.2025.102050","url":null,"abstract":"<div><h3>Purpose</h3><div>This review aims to outline comprehensive care for byssinosis, covering its pathophysiology, diagnosis, clinical characteristics, and physiotherapist-led interventions.</div></div><div><h3>Materials and methods</h3><div>We conducted a thorough literature review focusing on the pathophysiology, diagnosis, and management of byssinosis. Key components of care were identified through analysis of studies, guidelines, and expert opinions, with particular attention to physiotherapist interventions.</div></div><div><h3>Results</h3><div>Byssinosis progresses through three stages, with varying symptoms, yet its burden in India remains poorly understood, leading to inadequate prevention and management efforts. Treatment involves education, supplemental oxygen, pulmonary rehabilitation, and symptom control, with physiotherapists playing a crucial role in their implementation.</div></div><div><h3>Conclusion</h3><div>Comprehensive care for byssinosis requires a tiered rehabilitation framework, considering its diverse clinical presentation. Physiotherapists are pivotal in delivering essential interventions and enhancing patient outcomes and well-being.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"33 ","pages":"Article 102050"},"PeriodicalIF":2.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}