种族是绝经后肥胖妇女母乳喂养与远端感觉多神经病变之间关系的调节因素

IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2025-06-10 DOI:10.1016/j.cegh.2025.102098

Jiayu Li , Somsook Santibenchakul , Sukanya Chaikittisilpa , Harnam Kaur , Unnop Jaisamrarn

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引用次数: 0

摘要

目的：我们旨在研究种族是否会调节美国绝经后肥胖妇女母乳喂养与远端感觉多神经病变之间的关系。方法本横断面研究纳入40岁及以上绝经后肥胖妇女。患有严重慢性疾病、足部截肢或健康信息不足的妇女被排除在外。使用10g单丝测试测量远端感觉多神经病变，并根据简短问卷的回答收集自我报告的母乳喂养数据。使用多变量逻辑回归来检验母乳喂养与远端感觉多神经病变之间的关系，以及种族对这种关系的调节作用。结果在767名符合条件的妇女中，母乳喂养是远端感觉多神经病变的保护因素[校正优势比(OR) = 0.24, 95%可信区间（CI） 0.08-0.78；p = 0.019]。在调整种族与母乳喂养的显著双向相互作用后，观察到几率显著降低(调整后OR = 0.02, 95% CI 0.003-0.17；p = 0.001)。结论母乳喂养与远端感觉多神经病变之间的关系因种族而异，在西班牙裔妇女中观察到强烈的保护作用。这些发现强调需要进一步研究和针对不同人群的量身定制的公共卫生战略。

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Ethnicity as a modifier of the association between breastfeeding and distal sensory polyneuropathy in postmenopausal obese women

Purpose

We aimed to examine whether ethnicity moderates the association between breastfeeding and distal sensory polyneuropathy in postmenopausal obese women in the United States.

Methods

In this cross-sectional study, postmenopausal obese women aged 40 and over were included. Women with major chronic diseases, foot amputation, or insufficient health information were excluded. Distal sensory polyneuropathy was measured using a 10-g monofilament test, and self-reported breastfeeding data were collected based on responses to a brief questionnaire. Multivariable logistic regression was used to examine the association between breastfeeding and distal sensory polyneuropathy, as well as the modifying effect of ethnicity on this association.

Results

Among 767 eligible women, breastfeeding was a protective factor for distal sensory polyneuropathy [adjusted Odds Ratio (OR) = 0.24, 95 % confidence interval (CI) 0.08–0.78; p = 0.019]. Upon adjusting the significant two-way interaction of ethnicity with breastfeeding, a significant reduction in the odds was observed (adjusted OR = 0.02, 95 % CI 0.003–0.17; p = 0.001).

Conclusions

The association between breastfeeding and distal sensory polyneuropathy varied by ethnicity, with a strong protective effect observed in Hispanic women. These findings highlight the need for further research and tailored public health strategies in diverse populations.

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.