2023- 2024年在泰米尔纳德邦Sivakasi参加儿童综合发展服务（ICDS）项目的消瘦和重度消瘦儿童队列的治疗结果及其相关因素

IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2025-07-30 DOI:10.1016/j.cegh.2025.102145

Sabarish Prabhu , Srinivasan Ramalingam , Sendhilkumar Muthappan , Divya Saravanakumar , Arshi Chawla , Rizwan Suliankatchi Abdulkader

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引用次数: 0

摘要

本研究旨在估计2023-2024年期间泰米尔纳德邦Sivakasi卫生单位区的Srivilliputhur街区诊断为消瘦或严重消瘦的6-59个月儿童在四个月随访期间的恢复和复发发生率。方法我们在2023年12月诊断为消瘦或严重消瘦的6-59月龄儿童中进行了一项前瞻性队列研究。我们使用结构化问卷收集数据。基线评估于2023年12月进行，每月随访至2024年4月（T4）。为了确定与康复和复发相关的因素，我们首先进行了单变量分析，然后进行了多变量泊松回归分析。使用Sankey图可视化恢复和复发的途径，同时绘制Kaplan-Meier生存曲线来说明随时间的恢复和复发率。结果共纳入78名儿童，中位年龄为23个月。康复率为9.02 / 1000人日，复发率为3.96 / 1000人日。平均恢复时间为77.5天，而平均复发时间为84.5天。影响康复的因素包括年龄、饮食偏好和护理人员职业，其中治疗性饮食在改善预后方面起主要作用。结论本研究强调了有针对性的营养干预和综合护理策略对有效控制儿童消瘦的迫切需要。调查结果强调，必须持续监测和采取有针对性的办法，以提高康复率并尽量减少复发，最终有助于改善儿童健康和社会经济发展。

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Treatment outcomes and their associated factors among a cohort of children with wasting and severe wasting enrolled in the Integrated Child Development Services (ICDS) program in Sivakasi, Tamil Nadu, 2023-24

Background

This study aimed to estimate the incidence of recovery and relapse over a four-month follow-up period among children aged 6–59 months diagnosed with wasting or severe wasting in the Srivilliputhur block of the Sivakasi Health Unit District, Tamil Nadu, during 2023–2024.

Methods

We conducted a prospective cohort study among children aged 6–59 months diagnosed with wasting or severe wasting in December 2023. We collected the data using structured questionnaires. Baseline assessments were conducted in December 2023 (T0), with monthly follow-ups until April 2024 (T4). To identify factors associated with recovery and relapse, we first conducted a univariate analysis, followed by a multivariable Poisson regression analysis. Pathways of recovery and relapse were visualized using a Sankey diagram, while Kaplan-Meier survival curves were plotted to illustrate recovery and relapse rates over time.

Results

A total of 78 children were enrolled, with a median age of 23 months. The incidence of recovery was 9.02 per 1000 person-days, while relapse incidence was 3.96 per 1000 person-days. The mean time to recovery was 77.5 days, whereas the mean time to relapse was 84.5 days. Factors influencing recovery included age, dietary preference, and caregiver occupation, with therapeutic diets playing a major role in improving outcomes.

Conclusions

This study highlights the critical need for targeted nutritional interventions and comprehensive care strategies to manage childhood wasting effectively. The findings underscore the importance of continuous monitoring and tailored approaches to enhance recovery rates and minimize relapse, ultimately contributing to improved child health and socio-economic development.

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.