Talanta最新文献

{"title":"A critical review of pesticides in aquatic environment: Current trends, environmental impacts, and advances in analytical extraction techniques.","authors":"Debasmita Datta, Bishwatma Biswas, Ayan Lodh, Vishal Kumar Parida, Sudha Goel","doi":"10.1016/j.talanta.2025.128094","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.128094","url":null,"abstract":"<p><p>Pesticides are applied in agricultural fields to manage pests and diseases that threaten crop health and productivity. However, their presence in natural water systems is a significant concern due to their persistent composition and complex molecular structures. Additionally, their toxic and recalcitrant nature poses potential risks, leading to chronic health effects in humans. Typically detected in trace concentrations, pesticides present analytical challenges owing to their intricate chemical structures and diverse physical properties. Recent research highlights notable advancements in conventional pesticide extraction methods, aiming to develop eco-friendly and cost-effective techniques with high enrichment and recovery rates. This review begins by exploring the latest trends and ongoing research related to the occurrence and extraction of pesticides from various aquatic environments. The study then discusses the innovative extraction techniques currently employed for pesticide removal. Among liquid-phase microextraction (LPME) techniques, methods such as ionic liquid-based extraction (IL-LPME), deep eutectic solvent-based extraction (DES-LPME), air-assisted extraction, solidification of a floating organic drop (SFO), and ultrasound-assisted LPME are gaining attention due to their ease of handling, operational simplicity, cost-effectiveness, and environmental sustainability. In the, solid-phase extraction (SPE) field, researchers have increasingly utilized approaches like magnetic solid-phase extraction (MSPE), green sorbents, metal-organic framework (MOF) based extraction, cartridge-based SPE, and carbon nanotube-based SPE as the most widely adopted methods. These methods are preferred for their benefits, including efficient separation, rapid analysis, and environmentally sustainable practices. The latter sections of this review present a detailed comparative analysis of these extraction methods, evaluating critical parameters such as operational time, cost, chemical and energy consumption, and analytical accuracy.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"128094"},"PeriodicalIF":5.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional AuNRs/MXene/NFs -based SERS platform for determination of quetiapine in urine.","authors":"Jiamin Gong, Boran Zhang, Qinyi Li, Jiangli Shi, Xinling Liu, Yiping Wu, Ying Wen, Xiaoyu Guo, Haifeng Yang","doi":"10.1016/j.talanta.2025.128157","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.128157","url":null,"abstract":"<p><p>Determination of antipsychotic drugs in humans is meaningful for both individualized therapy and therapeutic drug monitoring. Quetiapine (QTP), as one of the newly developed antipsychotic drugs, may pose risks to human health if used improperly. In this work, we synthesized a three-dimensional (3D) Au nanorods/MXene (Ti₃C₂T_x)/nickel foams (named as AuNRs/MXene/NFs) composite material for detecting the antipsychotic drugs QTP. The prepared negatively charged MXene was first assembled on the surface of the NFs through electrostatic interaction to form MXene/NFs, and then the prepared AuNRs were anchored on the MXene/NFs to obtain the final 3D AuNRs/MXene/NFs. By integrating the porous structure and magnetic properties of NFs, large specific surface area of MXene, and the plasmonic hot spots of Au nanorods, the AuNRs/MXene/NFs-based SERS platform can easily and sensitively detect QTP in human urine with the limit of detection of 1.71 × 10^-9 mol/L. The linearity was distinguished over the concentration range of QTP from 1 × 10^-7 to 1 × 10^-4 mol/L (calculated at 1030 cm^-1), with correlation coefficients (R²) of 0.9955. The presented AuNRs/MXene/NFs-based SERS strategy realizes QTP detection using SERS technology and provides a novel protocol for the therapeutic drug monitoring.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"128157"},"PeriodicalIF":5.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A smartphone sensing colorimetric detection of ascorbic acid in fruit samples based on Cu₂Fe(CN)₆@PVP nanozyme.","authors":"Xinyu Zhang, Xuan Zhou, Quan Wan, Taolei Sun, Guanbin Gao","doi":"10.1016/j.talanta.2025.128152","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.128152","url":null,"abstract":"<p><p>Prussian blue analogue nanozymes (PBANZs) have been widely employed in the colorimetric detection of various organic small molecules due to their peroxidase-like activity. However, the practical applications of PBANZ are limited by its narrow operating pH range, insufficient catalytic activity, and poor stability. In this study, we synthesized a novel Cu₂Fe(CN)₆@PVP PBA nanozyme (Cu-PBANZ) using polyvinylpyrrolidone (PVP) as a capping ligand. This novel Cu-PBANZ not only exhibited enhanced peroxidase-like activity and improved stability under near-neutral conditions but also demonstrated higher sensitivity and a broader linear range in the detection of hydrogen peroxide (20-4000 μM, LOD 5 μM) and ascorbic acid (10-2000 μM, LOD 3.9 μM). Besides, a smartphone-based platform was developed for detecting AA content in fruits, achieving a detection limit of 7.8 μM. Both UV-Vis spectrophotometry and smartphone-based colorimetry were validated with recovery rates of 95.1 %-106.7 % and 94.8 %-108.9 %, respectively. This study proposed a promising biosensor incorporating Cu-PBANZ for rapid colorimetric detection of AA in fruits using a smartphone.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"128152"},"PeriodicalIF":5.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic recyclable metal-organic framework sheets grafted with curcumin for highly efficient adsorption and sensitive detection of fluoride.","authors":"Shisen Li, Yinghui Wang, Zhaopeng Yang, Ping Liu, Yanting Ren, Yue Li, Haiyan Jiang, Qingli Yang, Junghwan Kim, Yongchao Ma","doi":"10.1016/j.talanta.2025.128156","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.128156","url":null,"abstract":"<p><p>The contents of fluoride in drinking water should be limited to a safe range. Hence, design and development of a simple and efficient technology for adsorption and detection of fluoride is urgently required. We presented a curcumin in situ grafted MOF magnetic material (Fe₃O₄/MOF-Cur) for dual-functionalized applications of fluoride detection and adsorption. Owing to the electrostatic interaction, ligand exchange at the metal sites and boron-fluorine complexation, the adsorption capacity of Fe₃O₄/MOF-Cur for fluoride is 99.92 mg/g, and the detection limit is 1.17 μM. The fluoride adsorption behavior on different active units was further visualized by theoretical calculations. Favorable stability (79.52 mg/g after 5 adsorption-desorption cycles and insignificant change of fluorescence intensity within 30 days), mild reaction conditions (pH = 3-5) and excellent anti-interference ability promote the application of Fe₃O₄/MOF-Cur in real samples. Finally, the paramagnetic properties (29 emu/g) allow for easy recovery from water. These findings deepen the understanding on the design and development of dual-functionalized MOF materials, and prove the application potential of Fe₃O₄/MOF-Cur for the remediation of fluoride-related environmental pollution.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"128156"},"PeriodicalIF":5.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Femtomolar-level detection of procalcitonin using a split aptamer-based fiber optic nanogold-linked sorbent assay for diagnosis of sepsis.","authors":"Yen-Ta Tseng, Yi-Hyuan Yu, Ying-Yi Yeh, Phuong Chi Mai, Tze-Ta Huang, Chun-Jen Huang, Lai-Kwan Chau, Yuh-Ling Chen","doi":"10.1016/j.talanta.2025.128150","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.128150","url":null,"abstract":"<p><p>Sepsis requires very sensitive and rapid detection of biomarkers to guide antibiotic therapy to lower the patient mortality rate. Here, we report an ultrasensitive, rapid, and low-cost method for detection of the most popular sepsis biomarker, procalcitonin (PCT), based on a split aptamer-based fiber optic nanogold-linked sorbent assay. After successful development of a novel aptamer for PCT by SELEX, a pair of split aptamer fragments from the parent aptamer was predicted through molecular interaction simulation via free webservers. Then one fragment (AptF1) is modified on a sensor fiber and the other fragment (AptF2) is conjugated to a gold nanoparticle (AuNP@AptF2). The interactions among PCT and the two aptamer fragments lead to the formation of a AuNP@AptF2-PCT-AptF1 sandwich-like nanocomplex on the fiber core surface, leading to strong nanoplasmonic absorption near the fiber core surface. This method provides a linear response ranging from 500 fg/mL to 5.0 ng/mL and a detection limit of 50 fg/mL (3.9 fM). The method had been validated against the clinical accepted electrochemiluminescence immunoassay using clinical samples and very good correlation between the results by both methods was found. Therefore, this method offers a potential for point-of-care diagnosis of sepsis.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"128150"},"PeriodicalIF":5.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chitosan-platinum nanozyme-mediated ratiometric fluorescent immunosensor with dual catalytic cascades for sensitive detection of fenitrothion.","authors":"Jie Liu, Hao Deng, Qing-Chun Yin, Min-Fu Wu, Lin Luo, Hong Wang, Zhen-Lin Xu, Bao-Zhu Jia","doi":"10.1016/j.talanta.2025.128162","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.128162","url":null,"abstract":"<p><p>Organophosphorus pesticide residues pose significant threats to food safety and environmental health, and their monitoring methods demand sensitivity and anti-interference capability. In this study, we developed a novel ratiometric fluorescent immunosensor for fenitrothion (FN) detection by employing chitosan-modified platinum nanoparticles (Ch-Pt NPs) as catalytic nanozymes. Ch-Pt NPs exhibit oxidase-mimicking activity, enabling the oxidation of ascorbic acid (AA) and o-phenylenediamine (OPD) to produce dehydroascorbic acid (DHAA) and 2,3-diaminophenazine (DAP, Em = 568 nm), respectively. Then, DHAA further reacted with the remaining OPD to generate quinoxaline derivatives (DFQ, Em = 430 nm). These two products further form ratiometric fluorescent signals. Taking AA as a breakthrough point, the dual-catalytic cascade of natural enzymes and nanozymes was achieved by the combination with the alkaline phosphatase (ALP) -based enzyme-linked immunosorbent assay (ALP-ELISA). Compared with the conventional colorimetric ELISA, the proposed sensor demonstrated a nearly 20-fold enhancement in sensitivity (detection limit: 0.48 ng/mL) and achieved satisfactory recoveries of 80.0-108.3 % in spiked samples. The ratiometric fluorescent immunosensor demonstrates outstanding performance and holds great potential for extensive applications in the field of pesticide monitoring.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"128162"},"PeriodicalIF":5.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An AIE fluorescence probe for ratiometric and selective detection of Sn²⁺ based on proton transfer.","authors":"Duo-Duo Hu, Guangnan Wei, Ping Yang, Dexin Fu, Kuiliang Li","doi":"10.1016/j.talanta.2025.128078","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.128078","url":null,"abstract":"<p><p>Detecting Sn²⁺ heavy metal ions is crucial for mitigating water pollution and safeguarding human health. This study involved the design and synthesis of a novel fluorescence probe, RTPE-IM, which is a combination of an aggregation-induced emission luminophore (TPE) and rhodamine B. The probe undergoes proton transfer in the presence of Sn²⁺ ion, displaying high selectivity and a low detection limit of 0.121 μM. The synthesis and application of this molecule offer a potential strategy for preventing environmental health risks.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"128078"},"PeriodicalIF":5.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Portable detection system for identifying unknown liquid drugs","authors":"Minji Jeon ,&nbsp;Yeon Hwa Kwak ,&nbsp;Junsub Kim ,&nbsp;Woo Jong Yu ,&nbsp;Yong Ho Kim ,&nbsp;Byeong-Kwon Ju ,&nbsp;Kunnyun Kim","doi":"10.1016/j.talanta.2025.128799","DOIUrl":"10.1016/j.talanta.2025.128799","url":null,"abstract":"<div><div>Detecting and identifying drugs at an incident scene is crucial for swift and accurate investigations. Existing drug detectors primarily analyze purified drugs by capturing particle or vapor samples, and these devices are often bulky, expensive, and inconvenient for field use. In this study, we present a portable detection system using a multichannel surface acoustic wave (SAW) sensor for identifying unknown liquid drugs. This sensor, based on Love-wave technology operating at 318 MHz, enhances sensitivity and enables detection through an immunoassay method. Each sensor channel was functionalized with a drug conjugated to bovine serum albumin (BSA). To detect and identify an unknown drug, the unknown sample was mixed with a multi-antibody (multi-Ab) solution and injected into the sensor. Unbound antibodies adhered to the corresponding drug-BSA complex, resulting in a frequency shift due to the mass loading effect. This rapid binding process produced results within 1 min. The portable system integrates a custom-made frequency analyzer and detection module, forming a handheld device weighing less than 250g, suitable for real-time field analysis. The portable system successfully detected nine drug types, including methamphetamine (MA), morphine, cocaine, ketamine, methylenedioxy pyrovalerone (MDPV), fentanyl, heroin, zolpidem, and methcathinone. This innovative technology offers a cost-effective, portable solution for on-site drug identification, significantly improving detection speed, selectivity, and sensitivity to enhance investigative efficiency.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"298 ","pages":"Article 128799"},"PeriodicalIF":6.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145045535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dumbbell-shaped DNA topology drives self-sustaining CRISPR/Cas12a exponential amplification for ultrasensitive monitoring of DNA methyltransferase activity","authors":"Qian Xiang ,&nbsp;Wenjiao Zhou ,&nbsp;Daxiu Li","doi":"10.1016/j.talanta.2025.128841","DOIUrl":"10.1016/j.talanta.2025.128841","url":null,"abstract":"<div><div>DNA methylation is an essential epigenetic mechanism, and abnormal methylation has been linked to the onset and progression of many diseases, representing a potential threat to health. Monitoring DNA methyltransferase (MTase) activity is essential for understanding DNA methylation regulation and developing MTase-targeted inhibitors. To address this challenge, we developed a dumbbell-shaped DNA topology that drives self-sustaining (autocatalytic) CRISPR/Cas12a system for exponential signal amplification, enabling ultrasensitive fluorescent detection of DNA MTase activity. In this strategy, a DNA dumbbell topological structure (DDTS) is designed, in which two double-strand DNA (dsDNA) loops effectively block the activity of CRISPR/Cas12a. Upon Dam MTase presence, DpnI endonuclease cleaves the methylated recognition sites in the DNA probe, disrupting the DDTS topology to generate linear dsDNA activators. These activators restore the <em>trans</em>-cleavage of CRISPR/Cas12a, which further cleaves the single-stranded DNA (ssDNA) domain in DDTS probes to produce additional activators, creating an exponential amplification loop through autocatalysis. The system achieves a detection limit of 6.37 × 10⁻⁴ U/mL for Dam MTase, with a linear range of 1 × 10⁻³ to 15 U/mL, and shows excellent selectivity over other MTases and nucleases. It also enables inhibitor screening, with the half-maximal inhibitory concentration (IC₅₀) value of 1.84 μM for 5-fluorouracil. Therefore, the method has great potential for application in the early diagnosis of diseases and drug discovery.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"298 ","pages":"Article 128841"},"PeriodicalIF":6.1,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smartphone-assisted dual-mode fluorescent/ colorimetric biosensors based on Fe3O4-CDs nanozyme for self-calibrated detection of oxytetracycline","authors":"Long Bai,&nbsp;Jinsong Yu,&nbsp;Liling Hao,&nbsp;Cao Hui,&nbsp;Min Yuan,&nbsp;Xiuxiu Wu,&nbsp;Fengqin Yin,&nbsp;Tai Ye,&nbsp;Fei Xu","doi":"10.1016/j.talanta.2025.128839","DOIUrl":"10.1016/j.talanta.2025.128839","url":null,"abstract":"<div><div>Exploring multifunctional nanozyme-based analytical platforms is essential to broaden sensing modalities and enhance detection accuracy. In this study, we develop a composite Fe₃O₄–carbon dot (Fe₃O₄-CD) nanozyme that combines fluorescent emission, peroxidase-mimicking catalysis, and magnetic separation capabilities. Leveraging these features of Fe₃O₄-CD, a ratiometric fluorescence - colorimetric dual-mode biosensor was developed for the rapid, on-site, and visual analysis of oxytetracycline (OTC). Upon the addition of OTC, the red fluorescence of europium ions was significantly enhanced due to the antenna effect (AE), whereas the blue fluorescence of Fe₃O₄-CDs was diminished by the internal filter effect (IFE). These dual opposite fluorescence signal change enabling a highly sensitive ratiometric fluorescence detection (F₆₁₇/F₄₄₁). Concurrently, the peroxidase-like activity of Fe₃O₄-CDs was also enhanced by OTC, promoting the catalytic oxidation of TMB and generating a distinct colorimetric signal. Under optimal conditions, the limits of detection were as low as 1.8 nM for the colorimetric mode and 7.9 nM for the fluorescence mode. Moreover, this dual-mode sensing strategy can be seamlessly integrated with a smartphone-based platform, enabling portable, user-friendly, and instrument-free quantification, thereby demonstrating great potential for on-site testing applications. Moreover, satisfactory recovery results were obtained using the developed dual-mode sensing probe in spiked honey and water samples, demonstrating its practical applicability. This multifunctional nanozyme probe provides an alternative strategy for the rapid, sensitive, and accurate screening of oxytetracycline in environmental monitoring and food safety.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"298 ","pages":"Article 128839"},"PeriodicalIF":6.1,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}