Talanta最新文献 - Book学术

Rapid and enhanced detection of sulfonamide antibiotic using task-specific ionic liquids nanoconfined in tunable nanoporous carbons. 在可调纳米孔碳中使用任务特异性离子液体快速和增强检测磺胺类抗生素。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-18 DOI: 10.1016/j.talanta.2024.127396

Xu Xu, Yuhan Guo, Yuchi Liu, Zhuang Liu, Lei Zhang

{"title":"Rapid and enhanced detection of sulfonamide antibiotic using task-specific ionic liquids nanoconfined in tunable nanoporous carbons.","authors":"Xu Xu, Yuhan Guo, Yuchi Liu, Zhuang Liu, Lei Zhang","doi":"10.1016/j.talanta.2024.127396","DOIUrl":"10.1016/j.talanta.2024.127396","url":null,"abstract":"The development of a novel multifunctional adsorbent for the sensitive detection and capture of antibiotic residues in environmental and food samples presents a significant challenge. In this study, we synthesized a pioneering nanocomposite, ILs@PC, by encapsulating task-specific ionic liquids (ILs) within nitrogen-doped porous carbon (PC) derived from metal-triazolate frameworks. This ILs@PC nanocomposite functions as a multifunctional adsorbent in dispersive solid-phase extraction (DSPE), enabling simultaneous sorptive removal, sensitive detection, and molecular sieve selection. The ILs@PC demonstrated enhanced adsorption efficiency and sensitivity for sulfonamide antibiotics (SAs) compared to the pristine PC, attributed to the nanoconfinement effect of the ILs and the influence of pore volume on this effect. When integrated with high-performance liquid chromatography (HPLC), the ILs@PC-based DSPE method achieved a detection limit of 0.75-1.88 μg L-1 for SAs, along with satisfactory recoveries of 86.0 %-111.9 %. Additionally, a portable syringe device was developed to facilitate rapid on-site extraction and enrichment of SAs. The practicality of this method was validated through its successful application in detecting SAs in real samples, including lake water and milk. This approach highlights its potential for efficient and rapid monitoring of antibiotic residues in both environmental and food systems.","PeriodicalId":435,"journal":{"name":"Talanta","volume":"285 ","pages":"127396"},"PeriodicalIF":5.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A sequence-activatable dual-locked fluorescent probe for simultaneous detection of hypochlorous acid and peroxynitrite during drug-induced liver injury. 用于同时检测药物性肝损伤中次氯酸和过氧亚硝酸盐的序列激活双锁荧光探针。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-16 DOI: 10.1016/j.talanta.2024.127408

Caiyun Liu, Tingyi Yan, Xinyu Cai, Hanchuang Zhu, Peng Zhang, Xueting Liu, Xiaodi Rong, Kun Wang, Yao Wang, Wei Shu, Baocun Zhu

{"title":"A sequence-activatable dual-locked fluorescent probe for simultaneous detection of hypochlorous acid and peroxynitrite during drug-induced liver injury.","authors":"Caiyun Liu, Tingyi Yan, Xinyu Cai, Hanchuang Zhu, Peng Zhang, Xueting Liu, Xiaodi Rong, Kun Wang, Yao Wang, Wei Shu, Baocun Zhu","doi":"10.1016/j.talanta.2024.127408","DOIUrl":"10.1016/j.talanta.2024.127408","url":null,"abstract":"Drug-induced liver injury (DILI) is a crucial factor that poses a significant threat to human health. DILI process leads to the changes of reactive oxygen species and reactive nitrogen species content in cells, which leads to oxidative and nitrosative stress in cells. However, the high reactivity of hypochlorous acid (HOCl) and peroxynitrite (ONOO⁻), combined with a lack of in situ imaging techniques, has hindered a detailed understanding of their roles in DILI. Therefore, this paper reports a novel sequence-activatable dual-locked molecular probe HA-P3 for the identification and imaging of two DILI-related biomarkers. First, HA-P3 selectively reacts with reactive oxygen species HOCl to leave the recognition receptor diethyl thiocarbamate to form HA-P2. Subsequently, HA-P2 reacts with ONOO⁻, liberating the fluorophore 4-hydroxy-1,8-naphthalimide, which emits a strong fluorescence signal. The two-step reaction effectively reduces the probability of false positive in predicting DILI. HA-P3 achieved the sensitive detection of HOCl and ONOO- in different cells and zebrafish. Furthermore, HA-P3 can distinguish between normal liver cells and hepatoma cells and monitored the elevated levels of HOCl and ONOO⁻ during acetaminophen (APAP)-induced cellular damage. It is worth noting that in the APAP-induced mouse model, the positive correlation between HOCl and ONOO- and DILI was revealed, providing strong direct evidence for the relationship between oxidative/nitrosative stress and DILI.","PeriodicalId":435,"journal":{"name":"Talanta","volume":"285 ","pages":"127408"},"PeriodicalIF":5.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shades of red: A chemical exploration of pigments and dyes in 19th century postage stamps by a multi-analytical methodology. 红色的阴影：用多种分析方法对19世纪邮票上的颜料和染料进行化学探索。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-17 DOI: 10.1016/j.talanta.2024.127409

Simone C R Ferreira, M Conceição Oliveira, Alberto A C C Pais, J Sérgio Seixas de Melo

{"title":"Shades of red: A chemical exploration of pigments and dyes in 19th century postage stamps by a multi-analytical methodology.","authors":"Simone C R Ferreira, M Conceição Oliveira, Alberto A C C Pais, J Sérgio Seixas de Melo","doi":"10.1016/j.talanta.2024.127409","DOIUrl":"10.1016/j.talanta.2024.127409","url":null,"abstract":"A total of 57 European, Canadian and North American postage stamps, all in red shades, were analyzed with the main goal of unraveling which pigments or dyes were used to produce the red color in the period dated from 1841 to 1899. Both non-destructive techniques, including X-Ray Fluorescence (XRF), Fiber Optics Reflectance Spectra (FORS), and Steady State Fluorescence Spectroscopy, and destructive methods such as High-Performance Liquid Chromatography coupled with Diode-Array Detection (HPLC-DAD) and Electrospray Ionization High-Resolution Mass Spectrometry (ESI-HRMS), were utilized for a comprehensive analysis. The examined red shades were identified as originating from either a single pigment or dye, or a combination of both. XRF analysis detected red lead/litharge in 14 postage stamps, vermilion in 8 and iron oxide in 4. The mapping results obtained by this technique were shown to be very important in the determination of inorganic pigments. Most specimens contained a natural organic dye, with carminic acid being the most prevalent, appearing in 30 samples. In contrast, alizarin was identified in only 3 of the examined postage stamps. A synthetic dye, eosin Y, first synthesised by Heinrich Caro in 1871, was detected in 11 stamps and suggested by FORS and steady-state fluorescence in 6 others printed from 1879 onwards. HPLC-HRMS provided more detailed information on the natural colorant. In 19 samples both organic and inorganic dyes or pigments were found to coexist. It has been shown that spectroscopic techniques, when used with an appropriate database, can play a role in suggesting the presence of certain compounds that are subsequently detected by other techniques.","PeriodicalId":435,"journal":{"name":"Talanta","volume":"285 ","pages":"127409"},"PeriodicalIF":5.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

UV-activated gas sensor based on ordered mesoporous ZnO-TiO₂ heterogeneous composites for trace NO₂ detection at room temperature. 基于有序介孔ZnO-TiO2非均相复合材料的室温下痕量NO2检测紫外活化气体传感器。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-22 DOI: 10.1016/j.talanta.2024.127415

Yuan-Yuan Guo, Xiao-Hong Zheng, Liang-Bo Bo, Zi-Qi Gu, Cheng Zhang, Yu-Feng Liu

{"title":"UV-activated gas sensor based on ordered mesoporous ZnO-TiO2 heterogeneous composites for trace NO2 detection at room temperature.","authors":"Yuan-Yuan Guo, Xiao-Hong Zheng, Liang-Bo Bo, Zi-Qi Gu, Cheng Zhang, Yu-Feng Liu","doi":"10.1016/j.talanta.2024.127415","DOIUrl":"10.1016/j.talanta.2024.127415","url":null,"abstract":"The growing modern industry has promoted the development of gas sensors for environmental monitoring and safety checks. However, the traditional chemical resistance gas sensor still has some disadvantages such as high power consumption and limited detection, mainly due to the lack of charge transfer ability of sensing materials. In this paper, an ordered UV-activated gas sensor with mesoporous ZnO/TiO2 nanotube composite was prepared by precisely controlling the growth of ZnO on the inner wall of TiO2 nanotube. Based on the synergistic effect of Knudsen diffusion, photoactivation, and in situ heterojunction amplification, the charge transfer performance under room temperature of ZnO/TiO2 nanotube composites is improved. Compared to TiO2 nanotube sensor, the ZnO/TiO2 sensor has a 10-fold enhanced response to NO2, and the detection limit is as low as 50 ppb. Moreover, we studied the performance of ZnO/TiO2 sensor on NO2 in campus, street entrance and chemical plant, and comparing with commercial sensor, found that the detection error and detection limit of our sensor is lower, which proves the sensor has great application prospect in practical detection. This work provides a successful method for in-situ construction of ordered mesoporous materials and gives a solution for the design of advanced photoelectric gas sensors.","PeriodicalId":435,"journal":{"name":"Talanta","volume":"285 ","pages":"127415"},"PeriodicalIF":5.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Using a sensitive screen-printed electrode based on printex L6 and polyaniline activated carbon for piroxicam detection. 采用基于printex L6和聚苯胺活性炭的灵敏丝网印刷电极检测吡罗西康。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-20 DOI: 10.1016/j.talanta.2024.127412

Anderson M Santos, Taynara O Silva, Maria H A Feitosa, Igor G S Oliveira, Ademar Wong, Robson S Souto, Fernando C Moraes, Luís A M Ruotolo, Willyam R P Barros, Marcos R V Lanza

{"title":"Using a sensitive screen-printed electrode based on printex L6 and polyaniline activated carbon for piroxicam detection.","authors":"Anderson M Santos, Taynara O Silva, Maria H A Feitosa, Igor G S Oliveira, Ademar Wong, Robson S Souto, Fernando C Moraes, Luís A M Ruotolo, Willyam R P Barros, Marcos R V Lanza","doi":"10.1016/j.talanta.2024.127412","DOIUrl":"10.1016/j.talanta.2024.127412","url":null,"abstract":"This study reports the development and implementation of a straightforward, rapid, and cost-effective voltammetric technique for piroxicam (PIR) detection at nanomolar concentrations in biological and environmental samples. The method involved the use of a screen-printed electrode (SPE) enhanced with a combination of Printex L6 carbon (PL6C) and polyaniline-based activated carbon (PAC) on a chitosan film crosslinked with epichlorohydrin (CTS:EPH). The detection was carried out using square-wave adsorptive anodic stripping voltammetry (SWAdASV) in a 0.10 mol L-1 phosphate buffer solution at pH 6.0. The approach employed yielded a low limit of detection of 4.5 × 10-9 mol L-1 and a linear range of 5.0 × 10-8 to 8.8 × 10-6 mol L-1 (r = 0.999). The PAC-PL6C-CTS:EPH/SPE sensor was effectively employed for PIR detection in synthetic urine and river water samples, where its reliability was proven through addition and recovery tests. The results obtained from the application of the proposed voltammetric method closely matched those recorded under high-performance liquid chromatography (HPLC), which was used as a reference method. The findings show that the technique proposed in this study offers a simple, quick, and highly effective alternative mechanism for PIR detection in both biological and environmental matrices.","PeriodicalId":435,"journal":{"name":"Talanta","volume":"285 ","pages":"127412"},"PeriodicalIF":5.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Direct multi-element analysis of biological samples in dry matrix spots by PIXE. 用pxie直接多元素分析干基质斑点生物样品。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-15 DOI: 10.1016/j.talanta.2024.127394

Matea Krmpotić, Madina Telkhozhayeva, Merav Nadav Tsubery, Nitza Goldenberg-Cohen, Olga Girshevitz

{"title":"Direct multi-element analysis of biological samples in dry matrix spots by PIXE.","authors":"Matea Krmpotić, Madina Telkhozhayeva, Merav Nadav Tsubery, Nitza Goldenberg-Cohen, Olga Girshevitz","doi":"10.1016/j.talanta.2024.127394","DOIUrl":"10.1016/j.talanta.2024.127394","url":null,"abstract":"The dried matrix spot (DMS) method, initially developed for neonatal blood screening, has gained prevalence in various research fields for its efficiency in handling small sample volumes and its adaptability to diverse analytical techniques. This study presents the results of the first systematic investigation of direct multi-element analysis in DMS of human blood and plasma samples with Particle Induced X-ray Emission (PIXE). Internal standard addition was used to address the issue of DMS heterogeneity and to eliminate the need for determining the sample volume equivalent, allowing a single-spot (single-punch) measurement. The method was tested for linearity, accuracy, precision and limit of detection (LOD) using reference materials. It was applied to samples from healthy volunteers and compared to analysis results obtained by ICP-OES showing good agreement. Sample volumes as low as 50 μL were sufficient for the quantification of Na, Mg, P, S, K, Ca, Fe, and Zn in whole blood, and Na, Mg, P, S, K, and Ca in plasma samples without significant matrix effects being observed. Chlorine, which is also an electrolyte element present in high enough concentrations for determination by PIXE, was not addressed in this study due to a lack of reference materials. The results highlight PIXE as a viable alternative to other techniques that are sensitive to matrix issues, require larger sample volumes and/or sample treatment. Overall, this work establishes DMS sampling as being suitable for direct multi-element analysis of biological samples by PIXE, offering detection limits at the mg/L level which is sufficient for determination of electrolyte and essential trace elements and paving the way for its broader application in clinical and research settings.","PeriodicalId":435,"journal":{"name":"Talanta","volume":"285 ","pages":"127394"},"PeriodicalIF":5.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biologically-driven RAFT polymerization-amplified platform for electrochemical detection of antibody drugs. 用于抗体药物电化学检测的生物驱动RAFT聚合扩增平台。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-19 DOI: 10.1016/j.talanta.2024.127431

Jianwen Wan, Mengge Wang, Songmin Chen, Xiyao Zhang, Wenhui Xu, Di Wu, Qiong Hu, Li Niu

{"title":"Biologically-driven RAFT polymerization-amplified platform for electrochemical detection of antibody drugs.","authors":"Jianwen Wan, Mengge Wang, Songmin Chen, Xiyao Zhang, Wenhui Xu, Di Wu, Qiong Hu, Li Niu","doi":"10.1016/j.talanta.2024.127431","DOIUrl":"10.1016/j.talanta.2024.127431","url":null,"abstract":"The individualized administration and pharmacokinetics profiling are integral to the safe use of antibody drugs in immunotherapy. Here, we propose an electrochemical platform for the highly sensitive and selective detection of antibody drugs, taking advantage of the affinity capture by the peptide mimotopes together with the signal amplification by the biologically-driven RAFT polymerization (BDRP). Briefly, the BDRP-based platform involves the capture of antibody drugs by peptide mimotopes, the labeling of multiple reversible addition-fragmentation chain-transfer (RAFT) agents to the glycan chains of antibody drugs, and the BDRP-enabled controlled recruitment of numerous redox labels. The BDRP-based signal amplification relies on the reduction of RAFT agents by NADH coenzymes into the carbon-centered radicals, which can propagate efficiently into long polymer chains by reacting with the ferrocene-derivated monomers, recruiting numerous redox labels to the glycan chains of antibody drugs. The BDRP is conducted at the physiological temperature (i.e., 37 °C) and in the absence of external stimuli or radical sources, holding the advantages of biological compatibility and desirable simplicity over conventional RAFT polymerization approaches. The developed platform is highly selective and the detection limit in the presence of rituximab as the target was determined to be 0.14 ng/mL. Moreover, the applicability of the BDRP-based platform in the sensitive assay of antibody drugs in serum samples has been validated. In view of the biocompatibility, desirable simplicity, and cost-effectiveness, the BDRP-based platform shows great promise in the quantitative assay of antibody drugs.","PeriodicalId":435,"journal":{"name":"Talanta","volume":"285 ","pages":"127431"},"PeriodicalIF":5.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Manganese porphyrin wrapped DNA dendrimer as a universal chemiluminescence tag for ultrasensitive and multiplex assay of mycotoxins. 锰卟啉包裹DNA树状大分子作为一种通用化学发光标记，用于真菌毒素的超灵敏和多重检测。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-18 DOI: 10.1016/j.talanta.2024.127418

Qiushuang Tian, Haoyan Zhou, Ruike Wang, Ling Xu, Jun Chen, Chen Zong

引用次数: 0

Assembling MOF on CNTs into 0D-1D heterostructures for enhanced volatile organic compounds detection. 将碳纳米管上的MOF组装成0D-1D异质结构，以增强挥发性有机化合物的检测。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-20 DOI: 10.1016/j.talanta.2024.127444

Jiabao Ding, Junlong Qiao, Zichen Zheng, Zihao Song, Shumei Ding, Junhao Luo, Feihong Wang, Fengchao Li, Hongpeng Li

{"title":"Assembling MOF on CNTs into 0D-1D heterostructures for enhanced volatile organic compounds detection.","authors":"Jiabao Ding, Junlong Qiao, Zichen Zheng, Zihao Song, Shumei Ding, Junhao Luo, Feihong Wang, Fengchao Li, Hongpeng Li","doi":"10.1016/j.talanta.2024.127444","DOIUrl":"10.1016/j.talanta.2024.127444","url":null,"abstract":"The rapid advancement of the Internet of Things has created a substantial demand for portable gas sensors. Nevertheless, the development of gas sensors that can fulfill the demanding criteria of high sensitivity and rapid response time continues to pose a considerable challenge. Herein, an in-situ anchoring strategy is proposed to construct CNTs@MOF heterostructure to establish strong electronic coupling and charge relocation for enhancing the monitoring capabilities of isopropanol (freshness markers for fruits) at room temperature. The in-situ anchoring process prevents Zn-MOF (ZIF-8) self-aggregation, ensuring efficient transport channels for target analytes and enhancing active site utilization. Moreover, the synergistic effect of each component in the composite is optimized. Consequently, the gas sensor based on the CNTs@ZIF-8 heterostructure achieved an ultrahigh isopropanol response of 57.87 (40 ppm, Ra/Rg) at room temperature and 60% relative humidity, exhibiting rapid response kinetics (38 s, 30 ppm) and durability. This study offers a fresh perspective on the structural design of oxygen-inert CNTs materials.","PeriodicalId":435,"journal":{"name":"Talanta","volume":"285 ","pages":"127444"},"PeriodicalIF":5.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A saccharides regulated fluorescence ratio sensing array for bacterial recognition based on lectin response. 一种基于凝集素响应的糖调节荧光比传感阵列用于细菌识别。

IF 5.6 1区化学

Talanta Pub Date : 2025-04-01 Epub Date: 2024-12-17 DOI: 10.1016/j.talanta.2024.127419

Chunlan Liu, Haijing Zhang, Panpan Chen, Min Wang, Zhining Xia

{"title":"A saccharides regulated fluorescence ratio sensing array for bacterial recognition based on lectin response.","authors":"Chunlan Liu, Haijing Zhang, Panpan Chen, Min Wang, Zhining Xia","doi":"10.1016/j.talanta.2024.127419","DOIUrl":"10.1016/j.talanta.2024.127419","url":null,"abstract":"Array sensing employs cross-identification among analytes and various sensing units to identify substances or complex systems. This manuscript presents a fluorescence ratio sensing array based on lectin responses for the accurate identification of different bacteria. This strategy uses a saccharide-sensitive polymer as the sensing unit within the sensor. By incorporating various saccharides, it regulates the properties of the single sensing unit at the molecular level, altering its interaction with the analyte. This modulation leads to the generation of multiple distinct detection signals for the target, effectively facilitating the goal of array sensing. This approach streamlines the design and construction of the array sensor, while simultaneously enhancing detection efficiency. Not only does this sensing strategy achieve the differentiation and quantification of various types of lectins, but it also enables the identification of different bacterial species based on their unique lectin response profiles. This research introduces a novel approach that simplifies the construction of array sensors and simultaneously furnishes a potent tool for diagnosing and assessing bacterial infections within clinical settings.","PeriodicalId":435,"journal":{"name":"Talanta","volume":"285 ","pages":"127419"},"PeriodicalIF":5.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142870966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0