Talanta最新文献

{"title":"Dual-ligand-functionalized gold nanoparticles on ZIF-8: A bimodal ratiometric sensor for sensitive detection of penicillin G","authors":"Yi Ding,&nbsp;Zhiyuan Xu,&nbsp;Tianxia Chen,&nbsp;Mengxia Huang,&nbsp;Weiwei Li,&nbsp;Wenxin Ji,&nbsp;Xiangyu Liu","doi":"10.1016/j.talanta.2026.129383","DOIUrl":"10.1016/j.talanta.2026.129383","url":null,"abstract":"<div><div>Metal-organic frameworks (MOFs) provide a unique platform for tailoring the optical microenvironment of metal nanoparticles. However, simultaneously achieving high brightness, dual-emission self-calibration, and target-specific recognition remains challenging. In this sense, we prepare a dual-ligand engineered gold nanoparticle (Au NPs) system exhibiting well-resolved bimodal fluorescence. The Au NPs can be integrated with ZIF-8 via surface loading and in-situ encapsulation, respectively, yielding two kinds of composites. Comparative studies reveal that, compared to the in-situ encapsulated material (Au NPs@ZIF-8), the surface-loaded architecture (Au NPs/ZIF-8) demonstrates significantly higher quantum yield and photostability, thus enabling an optimal scaffold for sensing applications. Leveraging this, a ratiometric fluorescent probe is developed to linearly quantify penicillin G down to 0.8 nM in real samples with recoveries of 86–108 %. Notably, the dual-emission ratiometric is able to read-out mitigates matrix effects without sophisticated sample pretreatment, indicating robustness against turbidity and autofluorescence. This work proposes a new approach to fabricate high-performance ratiometric fluorescence sensors for sensitive detection of penicillin G in food and environment.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129383"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-immobilization of DNAzyme and horseradish peroxidase via biomineralization for electrochemical sensing of antibiotics","authors":"Tai Ye ,&nbsp;Shuying Yue ,&nbsp;Long Bai ,&nbsp;Haohao Chen ,&nbsp;Chenyang Li ,&nbsp;Rehemutula Wubuli ,&nbsp;Kehua Dang ,&nbsp;Min Yuan ,&nbsp;Hui Cao ,&nbsp;Ziqing Ye ,&nbsp;Fei Xu","doi":"10.1016/j.talanta.2026.129418","DOIUrl":"10.1016/j.talanta.2026.129418","url":null,"abstract":"<div><div>Co-immobilization of horseradish peroxidase (HRP) with G-quadruplex/hemin complex often suffer from low efficiency, intricate procedures, and reduced catalytic performance. To address these challenges, we developed a biomineralization strategy that integrates HRP and G-quadruplex/hemin into the single nanosheet structure. By engineering a split aptamer sequence into a G-rich domain, the nanosheets synergistically combine enhanced catalytic activity with better target-specific molecular recognition. Compared with either free HRP or it biomineralized counterpart alone, the prepared nanosheets exhibited markedly improved peroxidase-like activity. In the presence of enrofloxacin, specific aptamer-target binding facilitated the formation of a ternary complex on the electrode surface, enabling the catalysis of H₂O₂-mediated oxidation of TMB. Under the optimized conditions, the electrochemical aptasensor displayed a wide linear detection range of 1 nM–10 μM with a low detection limit of 0.53 nM. Beyond high selectivity, the sensor demonstrated excellent practical applicability in spiked milk and egg white samples. The generality of the developed platform was further confirmed by its successful extension to other antibiotics detection through replacing the split-aptamer pairs.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129418"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solid phase microextraction for urinary VOC analysis using portable GC-MS: Method development and validation against benchtop instrumentation","authors":"Mark Woollam ,&nbsp;Serenidy Eckerle ,&nbsp;Eray Schulz ,&nbsp;Sara Button ,&nbsp;Mangilal Agarwal","doi":"10.1016/j.talanta.2025.129329","DOIUrl":"10.1016/j.talanta.2025.129329","url":null,"abstract":"<div><div>Biological volatile organic compounds (VOCs) are expressed in noninvasive sample types such as urine and have emerged as promising biomarkers for disease detection. Gas chromatography-mass spectrometry (GC-MS) is the gold standard for VOC analysis, providing robust separation, quantification, and identification capabilities. While highly precise and accurate, benchtop GC-MS instruments require a large physical footprint and trained personnel for operation and data interpretation. Advancements in portable GC-MS technology have enabled point-of-care VOC analysis outside traditional laboratory settings, though most systems are designed for environmental and hazardous material detection. Therefore, the current study sought to develop a new method which is optimized to detect biological VOCs in urine headspace through solid phase microextraction (SPME) coupled with portable GC-MS. Method development included optimization of sample preparation, on-column, and MS parameters to improve sensitivity, repeatability, and chromatographic resolution. The SPME-based method was compared to another sampling method using the standard air probe, which demonstrated VOCs were enriched in SPME with an average log₂ fold change equal to 3.5. Intra- and inter-day repeatability was benchmarked through analysis of UTAK urine standards, which showed that VOCs generally displayed relative standard deviation (RSD) values below 25 %. Finally, samples from three healthy volunteers and the UTAK standard (n = 3 samples each) were analyzed using the portable GC-MS. This showed that the portable system could discern unique VOC trends between the volunteers. Compound identities and quantitative signal patterns were independently confirmed using a benchtop GC-MS, thus bringing confidence in the accuracy of the portable platform.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129329"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Portable and selective chloride ion detection in high-salinity water via a microwave sensor and synergistic precipitation-dielectric strategy","authors":"Xiao Liu ,&nbsp;Chonghui Yang ,&nbsp;Xiangwen Xing ,&nbsp;Guiqin Yang ,&nbsp;Gang Ding ,&nbsp;Qinglong Sun ,&nbsp;Zhanlong Song ,&nbsp;Ning Qin ,&nbsp;Pei Zhao ,&nbsp;Yong Dong","doi":"10.1016/j.talanta.2026.129434","DOIUrl":"10.1016/j.talanta.2026.129434","url":null,"abstract":"<div><div>Accurate detection of chloride ions (Cl⁻) in water is of great significance for ensuring human health and environmental safety. This study reports a cost-efficient, portable, and flexible microwave sensing system for detecting Cl⁻ in high-salinity water. This system employs a split ring resonator fabricated on a printed circuit board (PCB) substrate as the microwave sensor. The passivation layer covers the sensor to improve the sensitivity, prevent cross-contamination, and increase robustness. The integration of the sensor with a palm-sized LiteVNA for microwave signal acquisition facilitates portable Cl⁻ detection. To avoid the influence of other impurity ions and achieve high specificity in Cl⁻ detection, silver nitrate (AgNO₃) is added into the sample during testing. The reaction between Cl⁻ and AgNO₃ induces changes in the microwave signal caused by variations in dielectric properties, which corresponds to the Cl⁻ concentration. The detection is carried out over a Cl⁻ concentration range of 0–40 g L⁻¹ within the microwave frequency range of 0.5–3.5 GHz, whereas a characteristic peak appears between 0.9 and 1.2 GHz. The frequency shift before and after AgNO₃ addition is proportional to the Cl⁻ concentration and remains unaltered from various impurity ions. The optimized sensor design and AgNO₃ amount facilitate the system to obtain high sensitivity, excellent specificity, and rapid detection with a response time of 10 s.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129434"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toehold-mediated strand displacement in CRISPR/Cas12a reactions: Advances in programmable and universal biosensing strategies","authors":"David Septian Sumanto Marpaung ,&nbsp;Ayu Oshin Yap Sinaga","doi":"10.1016/j.talanta.2026.129442","DOIUrl":"10.1016/j.talanta.2026.129442","url":null,"abstract":"<div><div>CRISPR/Cas12a-based biosensors have emerged as powerful tools for nucleic acid detection due to their programmability, high sensitivity, and versatility. However, challenges such as PAM dependence, limited mismatch discrimination, and difficulty in detecting non-nucleic acid analytes constrain their universality. Toehold-mediated strand displacement (TMSD) offers a programmable mechanism to overcome these limitations by dynamically regulating hybridization kinetics and molecular interactions. This review systematically summarizes recent advances integrating TMSD into CRISPR/Cas12a systems, including crRNA release, crRNA–DNA activation, activator generation, and reporter signal modulation. By coupling TMSD's precise strand exchange capabilities with Cas12a's <em>trans</em>-cleavage activity, these hybrid biosensors achieve improved specificity, tunable kinetics, and multi-analyte adaptability. The review further discusses design principles, thermodynamic foundations, and application examples across biomedical, environmental, and food diagnostics. Collectively, TMSD-assisted CRISPR/Cas12a biosensing provides a universal, programmable framework for next-generation molecular diagnostics with enhanced control, sensitivity, and functional diversity.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129442"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146049756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyte-guided precise regulation of gold nanoflower etching mechanism for enhanced dopamine selectivity via bisphenol-triggered Schiff base/Michael addition and intramolecular hydrogen bond synergy","authors":"Hongyu Chen ,&nbsp;Jiayi Guo ,&nbsp;Xinrui Sun ,&nbsp;Peipei Tian ,&nbsp;Wenping Zhu ,&nbsp;Manman Sun ,&nbsp;Zengchen Liu ,&nbsp;Qingfeng Li ,&nbsp;Yahong Chen","doi":"10.1016/j.talanta.2026.129412","DOIUrl":"10.1016/j.talanta.2026.129412","url":null,"abstract":"<div><div>A novel nano-sensing system was developed to enhance the selectivity and sensitivity of dopamine (DA) detection by integrating the strong cleavage effect of β-mercaptoethylamine (MEA) on trypsin-stabilized gold nanoflowers (Trypsin-AuNFs), the Schiff base/Michael addition reactions triggered by the bisphenol structure of DA, and the intramolecular hydrogen bonding within DA. Multiple characterizations including TEM, XPS and FT-IR confirmed that trypsin was anchored on the flower-shaped surface of AuNFs via Au–S bonds, endowing Trypsin-AuNFs with excellent structural stability. In addition, Trypsin-AuNFs can both effectively prevent the interference of biothiols ((cysteine (Cys), homocysteine (Hcy), glutathione (GSH)) in serum and have a strong interaction with MEA, resulting in the rapid cleavage of Trypsin-AuNFs. This is because MEA both induced the cleavage of Trypsin-AuNFs through the formation of Au–S bonds, and directly interacted with trypsin, disrupting its structure and accelerating the decomposition of Trypsin-AuNFs. These dual actions significantly enhanced the selectivity and sensitivity of the sensing system. It is worth noting that a detailed study of the interaction between MEA and trypsin and the optimal binding site through molecular docking was conducted for the first time. A detailed study of the impact of MEA on the spatial structure of trypsin was also conducted for the first time by using molecular dynamics. Moreover, the precise regulation of the Trypsin-AuNFs cleavage mechanism triggered by the DA-bisphenol structure through a Schiff base/Michael addition reaction was thoroughly investigated using UV–vis absorption spectroscopy (including functional group identification, steric hindrance comparison, and bisphenol regulation), ¹H NMR, zeta potential measurements, and TEM. This work provides a novel strategy for probing the interaction between MEA and proteins and offers a new perspective for improving the specificity of DA detection.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129412"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards the detection of 2,4,6-trinitrotoluene with ionic liquid/poly(ionic liquid) membranes","authors":"Catherine E. Hay ,&nbsp;Elena Gorenskaia ,&nbsp;Juliette I. Phillips ,&nbsp;Adam Butterfield ,&nbsp;David Mecerreyes ,&nbsp;Debbie S. Silvester","doi":"10.1016/j.talanta.2026.129410","DOIUrl":"10.1016/j.talanta.2026.129410","url":null,"abstract":"<div><div>In this work, we explore a range of membranes based on ionic liquids (ILs) and poly(ionic liquid)s (poly(IL)s), with varying cation/anion combinations, for the electrochemical detection of 2,4,6-trinitrotoluene (TNT) using gold thin-film electrodes. The influence of the IL anion/cation structure, as well as the incorporation of a polycation, on the TNT reduction behaviour was systematically examined through cyclic voltammetry (CV) measurements. Among the studied systems, [C₂mim][TFSI]:p[DADMA][TFSI] and [C₄mim][TFSI]:p[DADMA][TFSI], where [C₂mim]⁺ = 1-ethyl-3-methylimidazolium, [C₄mim]⁺ = 1-butyl-3-methylimidazolium, [TFSI]^– = bis(trifluoromethylsulfonyl)imide and p[DADMA]⁺ = poly(diallyldimethylammonium), demonstrated an optimal balance between excellent electrochemical performance and high mechanical integrity, maintaining quasi-reversible TNT reduction with distinct three-step cathodic features. Environmental studies under controlled oxygen (0–25 vol %) and humidity (up to 95 % RH) environments revealed that the TNT response in real conditions is dependent on the membrane composition. These results highlight how ion-pair selection and environmental conditions jointly govern the charge transport and electrochemical behaviour in IL/poly(IL) membranes, providing key design principles for electrolytes in next-generation portable explosive sensors. The analytical performance of the sensing platform was evaluated using [C₂mim][TFSI]:p[DADMA][TFSI] and [C₄mim][TFSI]:p[DADMA][TFSI] membranes employing an ‘electrode surface-loaded with analyte’ detection strategy in which defined masses of TNT were deposited onto the electrode via solvent evaporation prior to electrochemical measurement.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129410"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146016881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitive lateral flow immunoassay based on the use of Au@Pt nanozyme and aptamer-captured oriented antibodies for the detection of anti-Müllerian hormone","authors":"Kseniya V. Serebrennikova,&nbsp;Nadezhda S. Komova,&nbsp;Anatoly V. Zherdev,&nbsp;Boris B. Dzantiev","doi":"10.1016/j.talanta.2026.129462","DOIUrl":"10.1016/j.talanta.2026.129462","url":null,"abstract":"<div><div>The application of core@shell nanozymes as labeling materials integrating catalytic amplification with molecular recognition in immunoassay platforms is a challenging task, since antibody immobilization often reduces both antibody reactivity and nanozyme catalytic activity. In this work, an approach to the oriented immobilization of antibodies on the surface of Au@Pt nanozymes using an aptamer specific to the fragment crystallizable region of mouse immunoglobulin G is proposed. This approach ensures that the antigen-binding domains of antibodies remain fully accessible while preserving the peroxidase-mimicking activity of the Au@Pt nanoparticles. Using oriented immobilization approach, we developed lateral flow immunoassay for sensitive detection of anti-Müllerian hormone. The sandwich immunoassay format was implemented using a pair of monoclonal antibodies that recognize different epitopes of the antigen. In this work, three approaches to conjugation, including physical adsorption, covalent and oriented immobilization to form conjugate of monoclonal antibodies with Au@Pt nanozyme, were implemented and compared in lateral flow immunoassay. The peroxidase-like properties of the nanozyme provided enhanced coloration in the test zone of the strip as a result of a catalyzed transformation with the substrate. Due to the combined effect of the high catalytic efficiency of the Au@Pt nanoparticles and the oriented immobilization of monoclonal antibodies on the surface of the nanozyme, an ultra-low detection limit of 30 pg/mL with a detection range from 0.9 to 48 ng/mL was achieved for the detection of anti-Müllerian hormone. Nanozyme-based lateral flow immunoassay allowed to reduce the detection limit by 13 times compared to common gold nanoparticle-based lateral flow immunoassay. In addition, nanozyme-based lateral flow immunoassay, including the subsequent enhancing catalytic reaction step, takes 20 min and is easy to perform. The applicability of the developed lateral flow immunoassay for the determination of anti-Müllerian hormone was confirmed by testing serum samples and revealed good recovery rates. Thus, the high analytical performance of the proposed lateral flow immunoassay demonstrates potential for anti-Müllerian hormone testing in point-of-care conditions. Moreover, the oriented immobilization of antibodies in the detection probe via the aptamer can be used as a versatile tool to improve the sensitivity of different lateral flow immunoassays.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129462"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Nanozyme-catalyzed SERS sensor combined with a competitive recognition strategy for diabetic retinopathy-associated VEGF detection\" [Talanta 298 (2026) 129006].","authors":"Jingwen Zhu, Xia Zong, Lian Pan, Xiaowei Cao, Changhua Lu","doi":"10.1016/j.talanta.2025.129260","DOIUrl":"10.1016/j.talanta.2025.129260","url":null,"abstract":"","PeriodicalId":435,"journal":{"name":"Talanta","volume":" ","pages":"129260"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145984183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional fluorescence analysis of bloodred webcap (Cortinarius sanguineus)-based dye on wool dyed with different methods","authors":"Elsa Vanker ,&nbsp;Sigrid Selberg ,&nbsp;Todd Pagano ,&nbsp;Sofja Tshepelevitsh ,&nbsp;Koit Herodes ,&nbsp;Ivo Leito","doi":"10.1016/j.talanta.2025.129334","DOIUrl":"10.1016/j.talanta.2025.129334","url":null,"abstract":"<div><div>This work focused on understanding the influence of dyeing methods and dye origin on the fluorescence spectra of wool yarns dyed with bloodred webcap (<em>Cortinarius sanguineus</em>), and exploring the potential and limitations of non-invasive fluorescence spectrometry in differentiating natural dyes on wool textiles.</div><div>Wool fibers dyed with bloodred webcap specimens from five different geographic origins or with emodin standards, and using nine different mordanting procedures, were investigated using three-dimensional (3D) fiber optic fluorescence spectrometry, resulting in a dataset of 20 excitation-emission matrices (EEMs). In addition, the effect of self-absorption on EEMs of this dataset was investigated. The ability of the fluorescence-based method to discriminate dyes from different taxonomic families was also assessed by combining the bloodred webcap data with EEMs from a more diverse dataset which includes 18 different species.</div><div>The dyeing method had some effect on the collected EEMs, potentially complicating the identification of a dye source in a historical textile if the mordanting procedure is unknown. The geographic origin of the fungi samples in this dataset showed minimal impact on the fluorescence spectra. Principal component analysis of a more diverse set of EEMs was helpful in differentiating dye taxonomic families, indicating utility of fluorescence spectrometry in qualitative determinations of some natural dye sources. While fluorescence alone may be insufficient for the unequivocal identification of natural dyes, this non-invasive, non-destructive, and rapid technique can provide useful additional information for identification when used in combination with other analytical techniques.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129334"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}