Talanta最新文献

{"title":"A disposable and ready-to-use liquid-filled stick microextraction method for the efficient extraction and determination of triazole fungicide residues in tea beverages and herbal extracts","authors":"Yuanyuan Zheng ,&nbsp;Manyi Wang ,&nbsp;Mengyuan Lv ,&nbsp;Yu Huang ,&nbsp;Bingyu Wang ,&nbsp;Chenqi Niu ,&nbsp;Di Chen","doi":"10.1016/j.talanta.2025.128187","DOIUrl":"10.1016/j.talanta.2025.128187","url":null,"abstract":"<div><div>This study presents a novel liquid-filled stick microextraction (LFSME) method for the efficient extraction of hydrophobic compounds from aqueous samples. The LFSME device, inspired by a single-use swab, consists of a hollow plastic stick pre-filled with a hydrophobic deep eutectic solvent (DES) and wrapped with polypropylene fabric at the end. Upon activation, the DES is released and absorbed by the polypropylene fabric, enabling direct immersion into the sample solution for efficient extraction. The extracted analytes are subsequently desorbed with acetonitrile and analyzed by liquid chromatography with ultraviolet detection. The method demonstrated excellent analytical performance, including high enrichment factors (34–90), good linearity (R² &gt; 0.99), and low limits of detection (LODs: 0.99–2.61 ng/mL) for the five target triazole pesticides. The disposable and portable nature of the LFSME device eliminates the need for complex sample handling, providing a cost-effective and user-friendly solution for routine monitoring of pesticide residues and other contaminants in complex matrices.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128187"},"PeriodicalIF":5.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143870435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The MoS2/ZnO p-n heterostructure arrays for ultrasensitive ppb-level self-supporting NO2 gas sensors under UV irradiation","authors":"Zhiguang Pan,&nbsp;Hao Huang,&nbsp;Tianqi Wang,&nbsp;Hui Yu,&nbsp;Wenyuan Yang,&nbsp;Xiangting Dong,&nbsp;Ying Yang","doi":"10.1016/j.talanta.2025.128194","DOIUrl":"10.1016/j.talanta.2025.128194","url":null,"abstract":"<div><div>Light irradiation has emerged as a promising strategy to promote low operating temperatures of metal oxides semiconductors gas sensors. Traditional sensors have high operating temperatures, low electron-hole separation, and low gas response. Therefore, MoS₂/ZnO heterostructure arrays were synthesized based on ITO conductive glass by hydrothermal and calcination methods as self-supporting sensors. Self-supporting sensors overcome limitations of traditional sensor fabrication. The successful preparation of self-supporting sensors is confirmed by a series of tests. The response of the gas sensor is determined as R_g/R_a or R_a/R_g (R_a and R_g indicate the resistance of the sensor in air and test gases). Regarding the gas-sensing performance, MoS₂/ZnO-20 self-supporting sensor under UV irradiation exhibits ultrahigh response of 1088.43 to 10 ppm NO₂ at 80 °C, which is 47 times higher than pure ZnO (23.21). Furthermore, operating temperature under UV irradiation is reduced by up to 60 °C. Additionally, MoS₂/ZnO-20 self-supporting sensor demonstrates rapid response/recovery time (100/3 s), high selectivity, and ultralow theoretical detection limit (10.37 ppb). The p-n charge separation mechanism is employed to elucidate sensing mechanism of MoS₂/ZnO self-supporting sensor for NO₂ under UV irradiation. The efficient photogenerated carrier separation efficiency, large surface area, and the presence of multiple heterostructures are responsible for the high gas-sensing performance of MoS₂/ZnO self-supporting sensor. Therefore, this study offers insights into the fabrication of ultrasensitive self-supporting sensors for low-temperature detection of NO₂ under light irradiation.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128194"},"PeriodicalIF":5.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143870428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phage/aptamer dual-encoded hydrogel arrays integrated with microfluidic platforms for simultaneous detection of multiple food pathogens","authors":"Jie Xu ,&nbsp;Siwei Zhou ,&nbsp;Yuqi Zhang ,&nbsp;Huihui Wu ,&nbsp;Tianhua Li ,&nbsp;Lei Tan ,&nbsp;Ning Gan ,&nbsp;Jincan He","doi":"10.1016/j.talanta.2025.128209","DOIUrl":"10.1016/j.talanta.2025.128209","url":null,"abstract":"<div><div>Food pathogens pose significant threats to public health. This study presents a universal, sensitive and time-efficient microfluidic chip electrophoresis (MCE) platform for simultaneously detecting multiple food pathogens based on phage/aptamer dual-encoded hydrogel arrays. The arrays are comprised of “all-in-one” hydrogel slices embedded with the capturing probe of specific phages and sensing probe of ATP aptamer/complementary chain (A-Apt/cDNA) hybrid structures. The live bacteria are specifically captured and lysed by the corresponding phages to generate copious amounts of ATP. The ATP further combines with the A-Apt/cDNA hybrids to release the cDNA strands with various lengths from the hydrogel pores into the supernatant. Therefore, cDNA strands whose lengths are specific for each bacteria function as markers for ATP, the level of which represents the number of living bacteria. The qualitation and quantification of multiple bacteria is realized by isolating and analyzing various cDNA using MCE. Taking three food pathogens (i.e., <em>E</em>. <em>coli</em>, <em>Salmonella typhimurium</em>, <em>Staphylococcus aureus</em>) as target models, the platform were performed within 60 min, with detection limits of 20 CFU/mL, 30 CFU/mL and 15 CFU/mL, respectively. This study offers a universal and rapid strategy for multiple food pathogens analysis.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128209"},"PeriodicalIF":5.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chromatographic separation and ecological risk assessment of pristine and functionalized fullerene nanomaterials in wastewater and sea water by UHPLC –UV–vis","authors":"Nokwanda Hendricks,&nbsp;Olatunde S. Olatunji,&nbsp;Bhekumuzi P. Gumbi","doi":"10.1016/j.talanta.2025.128206","DOIUrl":"10.1016/j.talanta.2025.128206","url":null,"abstract":"<div><div>The broad usage of fullerenes nanomaterials and their associated toxicity to non-target organisms makes them an emerging environmental concern. Standard analytical methods to monitor their occurrence in the environment are lacking due to their unique chemical structures, which results in acute hydrophobicity leading to poor chromatographic separation. However, their environmental presence and potential environmental risks necessitate for careful monitoring and risk assessment in wastewater treatment plants and aquatic environments. In this study, a chromatographic technique using an Ultra High-Performance Liquid Chromatography (UHPLC) coupled with UV–visible detector was used for the separation and quantification of fullerene nanomaterials in wastewater and seawater. The chromatographic separation method developed focused on C60 fullerene, C70 fullerene, [6, 6]-phenyl C61 butyric acid methyl ester (C61-PCBM) and [6,6]- Thienyl- C61- butyric acid methyl ester (C61-TCBM). High resolution transmission electron microscopy (HRTEM) and ultraviolet–visible spectroscopy were used to determine the size, shape and absorption wavelength of colloidal fullerene nanomaterials. This method was used for quantification of colloidal fullerene nanomaterials in a wastewater treatment plant and aquatic environments and wastewater treatment plants to assess their risk. The percentage recoveries of fullerene nanomaterials from wastewater, tap water and sea water were investigated for all fullerene nanomaterials C61-PCBM, C61-TCBM, C60 and C70 were 84 %–108 %, 83 %–108 %, 97 %–116 % and 62 %–115 %, respectively. The fullerene nanomaterials C61-PCBM, C61-TCBM and C60 had a linear range at concentrations of 0.25 μg L⁻¹ to 50 μg L⁻¹, with linear regression of 0.9968, 0.9959, 0.9991 and 0.9914, respectively. C70 show a linear range between 0.5 μg L⁻¹ and 10 μg L⁻¹, with linear regression of 0.9914. The limit of detection for C61-PCBM, C61-TCBM, C60, and C70 were 0.0663 μg L⁻¹, 0.0262 μg L⁻¹, 0.0370 μg L⁻¹, and 0.0370 μg L⁻¹, respectively. The developed method was applied to determine the selected fullerene nanomaterials in wastewater and sea water. Their concentrations in wastewater and sea water range from not detected to 2.73 μg L⁻¹ and not detected to 2.05 μg L⁻¹, respectively. The ecological risk assessment carried out on fullerene in the investigated media was found to have no risk to medium risk.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128206"},"PeriodicalIF":5.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143864214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Au NUs@SiO2 sensors for sensitive and selective optical sensing of volatile compounds","authors":"Bin Chen ,&nbsp;Qirui Mou ,&nbsp;Chuanjun Liu ,&nbsp;Kenshi Hayashi","doi":"10.1016/j.talanta.2025.128207","DOIUrl":"10.1016/j.talanta.2025.128207","url":null,"abstract":"<div><div>Plasmonic sensors has been widely used to detect the refractive index change in liquids, while it is challenging to apply the plasmonic sensors to the selective detection of organic vapors that adsorb non-specifically and induce extremely low refractive index change. Herein, silica shell was directly grown on Au nano-urchins (Au NUs) through sol-gel hydrolysis method to improve its vapor molecules anchoring capability and generate the selectivity to different vapors. According to the vapor sensing experiments to ethanol, acetone and hexane, the refractive index sensitivity (RIS) of Au NUs@SiO₂ sensors was four times higher than that of bare Au NUs. In addition, Au NUs@SiO₂ sensors demonstrate different vapor sensing performance to different organic vapors. The sensing characteristics is attributed to the large contacting area and the affinity between Au NUs@SiO₂ sensors and the target molecules. These findings provide a basis for the development of novel plasmonic sensors and the RIS enhancement, which abroad their application as contactless sensors.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128207"},"PeriodicalIF":5.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cellulose paper decorated with gold(-silver) nanoparticles for SERS-based immunoassays","authors":"Tao Ma ,&nbsp;Xiaoqiang Dong ,&nbsp;Iris Liang ,&nbsp;Jiuzhou Chen ,&nbsp;Yi Tao ,&nbsp;Junling Chen ,&nbsp;Dandan Xu ,&nbsp;Feng Liang","doi":"10.1016/j.talanta.2025.128170","DOIUrl":"10.1016/j.talanta.2025.128170","url":null,"abstract":"<div><div>Surface-enhanced Raman scattering (SERS)-based immunoassays offer an unprecedented method for the early diagnosis of biomarkers. However, challenges in reliability often hinder their broader applications. This study introduces a novel approach employing in situ-prepared cellulose paper decorated with gold and gold-silver nanoparticles (Au(-Ag) CP) to construct a highly sensitive and stable paper-based SERS substrate. Building on this, we developed robust SERS immunosubstrates and immunoprobes, enabling a versatile immunoassay platform. This platform demonstrated exceptional performance in detecting disease markers. Using gold nanoparticles probe with Au CP, a limit of detection (LOD) of 29.71 fg/mL was achieved for the COVID-19 antigen, while the Au–Ag CP coupled with the Au-core Ag-shell (Au@Ag) probes achieved an LOD of 10.79 fg/mL for cardiac troponin I (cTnI). Both detection modes featured a broad dynamic range from 10⁻¹³ to 10⁻⁸ g/mL and sustained stability, retaining comparable LOD after 5 weeks of storage. The paper-based SERS immunoassay platform presented here holds promise for rapid, ultra-sensitive biomarker detection, offering a transformative tool for advancing diagnostic technologies.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128170"},"PeriodicalIF":5.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanism of pesticide thiram reversibly inhibiting of Pt single-atom peroxidase-mimicking nanozyme and its application in colorimetric sensing thiram","authors":"Ziting Lin ,&nbsp;Guangze Sun ,&nbsp;Huan Liu ,&nbsp;Xin Zhang,&nbsp;Zihan Bian,&nbsp;Aihua Liu","doi":"10.1016/j.talanta.2025.128201","DOIUrl":"10.1016/j.talanta.2025.128201","url":null,"abstract":"<div><div>Nanozymes hold great promise in catalysis-based sensing. However, little attention has been paid to inhibition mechanism of nanozymes, which impeded their sensing application. Herein, we report a sensitive colorimetric sensing platform for detecting pesticide tetramethylthiuram disulfide (thiram) based on its inhibition of Pt single-atom nanozymes (SAN)-based peroxidase (POD)-like activity. Thiram containing dimethyl dithiocarbamate (DMDTC) unit capable of inhibiting POD-like activity of Pt SAN because the disulfide bond was cleaved to form DMDTC, which further formed Pt–S bond with Pt SAN. The enzyme-substrate interaction and the substrate's inhibitory mechanism were investigated. Thiram can inhibit the POD-like activity of Pt SAN reversibly with mixed inhibition (competitive inhibition and non-competitive inhibition) and uncompetitive inhibition with the inhibition constants (<em>K</em>_i) of 9.079 and 0.382 mM, respectively. Finally, based on the inhibition mechanism, a colorimetric sensor was constructed, exhibiting two linear parts of 0.025–1 μM and 1–15 μM with a detection limit of 9.24 nM thiram. The as-proposed method can be applied to detect thiram in real samples with good reproducibility. This work not only lays the foundation for study on the inhibition mechanism between other nanozymes and inhibitors, but also provides a new method for detecting trace thiram in environmental samples.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128201"},"PeriodicalIF":5.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143870427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexible silver-metal-organic framework probe for highly sensitive and visual detection of tetracycline hydrochloride in freshwater fish","authors":"Yuanyuan Yin ,&nbsp;Jian Zhang ,&nbsp;Chengshan Ji ,&nbsp;Zeyu Zhao ,&nbsp;Xin Wang ,&nbsp;Ping Wang ,&nbsp;Yulin Yang","doi":"10.1016/j.talanta.2025.128200","DOIUrl":"10.1016/j.talanta.2025.128200","url":null,"abstract":"<div><div>Tetracycline hydrochloride (TCH) is commonly used in aquaculture to prevent bacterial infections, renders the detection of its residues highly crucial for ensuring the safety of aquatic products. In this study, an Ag-based metal-organic framework, Ag-dcp (H₃dcp = 3-(3,5-dicarboxyphenyl)-6-carboxypyridine), was synthesized through hydrothermal method. The Ag-dcp framework offers environmental advantages, including a green synthesis process and potential for sustainable, eco-friendly applications. The uncoordinated carboxyl groups in Ag-dcp provide potential interaction sites for TCH, while the rhombic channels in the flexible structure of Ag-dcp that match the size of TCH effectively facilitate host-guest interactions. The Ag-dcp enables ratiometric fluorescence detection with high sensitivity via intramolecular charge transfer (ICT) triggered by TCH-induced ether bond rotation. The probe demonstrates a fluorescence color changes from blue to orange, achieving a detection limit as low as 0.14 μM and offering an ultrafast response time of just 10 s. Principal component analysis (PCA) was employed to effectively distinguish TCH from other tetracycline analogs (minocycline hydrochloride (MH) and doxycycline hydrochloride (DOX)), thereby enhancing the selectivity of the Ag-dcp probe. The fluorescence probe demonstrated performance comparable to HPLC in detecting TCH in freshwater fish. The detection strategy proposed here, based on the MOF structure, offers valuable insights for designing MOF materials and their specialized applications.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128200"},"PeriodicalIF":5.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated duplex reverse transcription-recombinase aided amplification (RT-RAA) and lateral flow assay (LFA) for rapid simultaneous detection of Zika virus and Japanese encephalitis virus in single reaction format","authors":"Haolong Cong ,&nbsp;Xiaodong Han ,&nbsp;Mengyuan Lv ,&nbsp;Yutong Chang ,&nbsp;Xinyi Wang ,&nbsp;Rong Lei","doi":"10.1016/j.talanta.2025.128195","DOIUrl":"10.1016/j.talanta.2025.128195","url":null,"abstract":"<div><div>Zika virus (ZIKV) and Japanese encephalitis virus (JEV), two consequential mosquito-borne flaviviruses, induce severe systemic and neurotropic-encephalitic pathologies with overlapping symptoms profiles, complicating differential diagnosis in co-endemic regions. To address this critical challenge, we developed a dual reverse-transcription recombinase-aided amplification (RT-RAA) coupled with duplex lateral flow assay (LFA) platform for rapid, equipment-free co-detection of ZIKV and JEV in a single reaction tube. The assay achieved isothermal amplification at 39 °C within 40 min using a field-deployable incubator. The limit of detection (LOD) reached as low as 8.5 copies ZIKV RNA, and 1.1 copies JEV RNA in single pathogen detection, while 110 copies JEV RNA in co-detection mode. This technological advance bridges the critical sensitivity gap between lab-based PCR and conventional rapid tests, enabling first-line healthcare responders to conduct precision diagnostics in non-laboratory settings from rural clinics to mobile outbreak response units.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128195"},"PeriodicalIF":5.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing a polarity-specialized TICT fluorescent probe for wash-free and long-term monitoring lipid droplets dynamics","authors":"Tenghui Wang,&nbsp;Junhui Liu,&nbsp;Huihui Wei,&nbsp;Qinhong Jiang,&nbsp;Tianxin Yang,&nbsp;Xinyu Zhang,&nbsp;Panfei Xing","doi":"10.1016/j.talanta.2025.128191","DOIUrl":"10.1016/j.talanta.2025.128191","url":null,"abstract":"<div><div>Lipid droplets (LDs) are dynamic and multifunctional organelles that play a crucial role in energy storage, metabolism and lipid signaling. Monitoring the dynamics of LDs is essential for understanding their functions. Twisted intramolecular charge transfer (TICT)-based fluorescent molecules have been widely utilized for LD imaging. However, conventional TICT dyes exhibit sensitivity to both polarity and viscosity, which results in unclear sensing mechanisms for LDs. Additionally, current LD imaging techniques face challenges such as complex washing procedures and limited long-term imaging capabilities. This study presented a far-red coumarin framework designed to modulate the TICT-ICT equilibrium, resulting in the development of two fluorophores that exhibit specialized sensitivity to either polarity or viscosity. The findings suggested that sensitivity to polarity is a crucial factor for LD imaging, as high signal-to-noise ratios (SNR) enable wash-free imaging, while suitable lipophilicity supports long-term imaging. This polarity-specialized TICT probe had the potential to revolutionize LD imaging, facilitating wash-free and extended studies of LD dynamic behaviors and functions during lipolysis.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"294 ","pages":"Article 128191"},"PeriodicalIF":5.6,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}