Talanta最新文献

{"title":"Stabilizing an scu-topology Zr-MOF via linker installation for enhanced gas chromatographic separation","authors":"Chu Zeng ,&nbsp;Hong-Tao Jiang ,&nbsp;Ming Xu,&nbsp;Zhi-Yuan Gu","doi":"10.1016/j.talanta.2026.129469","DOIUrl":"10.1016/j.talanta.2026.129469","url":null,"abstract":"<div><div>Flexible metal–organic frameworks (MOFs) with dynamic adaptability offered exciting opportunities for advanced separation, yet their tendency to undergo void collapse severely limited their application as gas chromatography (GC) stationary phases. Here, we overcame this challenge by stabilizing the <strong><em>scu</em></strong>-topology Zr-MOF NU-903 through a linker installation strategy. By incorporating biphenyl-4,4′-dicarboxylic acid (BPDC) into the vacant coordination pockets along the c-axis, the resulting material, NU-903-BPDC, exhibited markedly enhanced stability and structural rigidity, retaining its porosity even at 250 °C. Comprehensive characterization confirmed that the original structure was preserved, while framework flexibility was effectively suppressed. Fluorescence spectroscopy further revealed restricted ligand dynamics, corroborating the rigidified framework environment. When employed as a GC stationary phase, NU-903-BPDC delivered significantly improved resolution for C₇ hydrocarbons and dichlorobenzene isomers, benefitting from stronger thermodynamic interactions and reduced band broadening. Crucially, NU-903-BPDC maintained stable separation performance after thermal treatment, in sharp contrast to the pronounced degradation observed for pristine NU-903. This work demonstrated linker installation as an effective strategy to modulate framework flexibility, opening a general pathway toward robust, high-performance MOF-based stationary phases for chromatographic separations.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"303 ","pages":"Article 129469"},"PeriodicalIF":6.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eu-MOF@Ce-MOF heterostructure and molecularly imprinted polymer composite system for SARS-CoV-2 point-of-care detection","authors":"Yunfei Gao ,&nbsp;Zi-Hao Zhao ,&nbsp;Minghao Ma ,&nbsp;Zhiwei Liu ,&nbsp;Xihui Mu ,&nbsp;Bing Liu ,&nbsp;Bin Du ,&nbsp;Mingzhu Xia ,&nbsp;Fengyun Wang ,&nbsp;Zhaoyang Tong","doi":"10.1016/j.talanta.2026.129477","DOIUrl":"10.1016/j.talanta.2026.129477","url":null,"abstract":"<div><div>Metal–organic frameworks (MOFs) have attracted growing interest as advanced sensing materials due to their structural tunability and functional versatility. The responsiveness of MOF-based sensors is typically governed by changes in either the metal centers or organic linkers, making it essential to engineer novel architectures that enhance sensing performance. In this work, we present a MOF-on-MOF heterostructure (Eu-MOF@Ce-MOF), composed of a europium-based framework (Eu-MOF) and a cerium-based counterpart (Ce-MOF), synthesized via a two-step hydrothermal strategy. The Eu-MOF was first prepared using 3,5-dicarboxybenzeneboronic acid (BBDC) as the linker with Eu (III) as the metal node, while Ce-MOF was synthesized using similar synthetic conditions with Ce (III). Subsequently, Ce-MOF was anchored onto the surface of Eu-MOF to form a dual-emission MOF-on-MOF heterostructure. To further expand the applicability of this hybrid material, we integrated it with molecularly imprinted polymers (MIPs) to construct the Eu-MOF@Ce-MOF@MIP composite, which serves as both a carrier matrix and an active sensing platform. This system enabled highly selective and sensitive detection of the SARS-CoV-2 spike protein (SP) via fluorescence quenching, achieving a low detection limit (LOD) of 0.012 μM. A smartphone-integrated sensing platform was developed to facilitate on-site detection of SP in complex real samples. The results demonstrated high selectivity, reproducibility, and long-term stability, with additional validation using simulated biological matrices (serum and urine) confirming the robustness of the method. This study establishes a versatile and portable sensing strategy for SARS-CoV-2 detection, with broad implications for point-of-care detection and biosensing applications.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"303 ","pages":"Article 129477"},"PeriodicalIF":6.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photoelectrochemical aptasensor for ultrasensitive detection of MUC1 based on titanium dioxide/polypyrrole/carboxy polyethylene glycol hybrid anti-fouling interface","authors":"Zhencui Wang,&nbsp;Jinbang Wang,&nbsp;Jun Zhang,&nbsp;Chunwei Yu","doi":"10.1016/j.talanta.2026.129466","DOIUrl":"10.1016/j.talanta.2026.129466","url":null,"abstract":"<div><div>Achieving ultrasensitive detection of MUC1 in the early stages of breast cancer is critical for reducing mortality and improving patient prognoses. Photoelectrochemical sensing has emerged as a promising technology for the detection of MUC1, primarily due to its straightforward operation and user-friendly instrumentation. However, titanium dioxide, a commonly used photoactive material, exhibits inherent limitations, including low charge carrier mobility and challenges related to non-specific adsorption in complex biological matrices. These issues significantly undermine the sensitivity of MUC1 detection, underscoring the urgent need for improved photoactive materials and sensing methodologies. Herein, we proposed a novel PEC aptasensor engineered with titanium dioxide/polypyrrole/carboxy polyethylene glycol (TNWs/PPy/C-PEG) hybrid anti-fouling interface via facile self-assembly. The composite of titanium dioxide nanowires and polypyrrole forms a heterojunction (TNWs/PPy) that extends the electron lifetime to 38.0 ms while significantly improving light utilization, carrier mobility, and photoelectric conversion efficiency. This enhancement ultimately amplifies the photoelectric current response. Furthermore, the negatively charged C-PEG anti-fouling unit is electrostatically anchored to the positively charged TNWs/PPy electrode surface, effectively preventing the adsorption of non-specific contaminants. Ultimately, MUC1 aptamers are immobilized on the TNWs/PPy/C-PEG photoelectrode, facilitating the selective capture of MUC1. The synergistic effects of TNWs/PPy electrode, specific recognition units, and anti-fouling layer led to a marked improvement in the selectivity and sensitivity. The detection limit of this aptasensor is 0.33 pg mL⁻¹, with a linear range from 1 pg mL⁻¹ to 500 ng mL⁻¹. Furthermore, satisfactory results were obtained in the measurement of MUC1 in serum samples. The electrostatic self-assembly strategy presents a straightforward and novel approach to ensuring the stability of anti-fouling sensing interfaces. Moreover, the incorporation of heterojunction formation for signal amplification, in conjunction with the synergistic construction of anti-fouling interfaces, offers an innovative solution for the development of advanced sensing platforms and the early detection of breast cancer.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"303 ","pages":"Article 129466"},"PeriodicalIF":6.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rational design of metal nanoclusters for environmental monitoring: A review","authors":"Yiqiu Xu ,&nbsp;Anyi Wang ,&nbsp;Kedi Yu ,&nbsp;Dadi Liu ,&nbsp;Hui Li ,&nbsp;Qianrou Fan ,&nbsp;Cheng Lv ,&nbsp;Yang He ,&nbsp;Xinlu Wang ,&nbsp;Yulu Li ,&nbsp;Zhengbo Chen ,&nbsp;Yebin Guan ,&nbsp;Xiaoxia Mao ,&nbsp;Yumin Leng","doi":"10.1016/j.talanta.2026.129482","DOIUrl":"10.1016/j.talanta.2026.129482","url":null,"abstract":"<div><div>As a category of functional nanomaterials with ultra-small size, excellent biocompatibility, and unique molecule-like physicochemical properties, metal nanoclusters (MNCs) have exhibited broad application prospects in the field of environmental detection over the past few years. Currently, through rational design, MNCs can be precisely integrated with various targeting moieties, which achieves the customized regulation of their physicochemical properties and functions. Compared with unmodified natural MNCs, MNCs modified with multifunctional surfaces possess more prominent advantages in environmental detection, such as improved detection sensitivity, enhanced selectivity, and reduced environmental interference. In this review, the preparation methods of gold, silver, copper, platinum and other single metals and their bimetallic/doped nanoclusters are systematically described. Secondly, the latest research progress of MNCs in the field of environmental detection is reviewed and summarized, including the application of pollutant detection based on their optical, electrochemical, and other properties. Finally, the key scientific issues and technical challenges faced by MNCs in the development of environmental detection are analyzed, and prospects for their future development direction and application prospects are put forward. The study seeks to provide theoretical and technical support for facilitating the practical application of MNCs in environmental detection.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"303 ","pages":"Article 129482"},"PeriodicalIF":6.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of high humidity environment on the time-resolved spectrum of laser-induced air plasma","authors":"Jianyong Cen,&nbsp;Xin Wang,&nbsp;Zeguang Li,&nbsp;Xinjie Huo,&nbsp;Jinjun Zhang","doi":"10.1016/j.talanta.2026.129476","DOIUrl":"10.1016/j.talanta.2026.129476","url":null,"abstract":"<div><div>Humidity is an important physical parameter that affects the measurement accuracy of laser-induced breakdown spectroscopy technology. The influence of high humidity on laser-induced air plasma at a microscopic perspective has been investigated by using a high-speed camera and high time-resolved (5 ns) spectrum. The morphological changes of air plasma under high humidity conditions were investigated. The effects of humidity on the spectral line intensity, peak time, lifetime, temperature, and electron density were analyzed. The results showed a positive correlation between the length of laser-induced air plasma and humidity. As humidity increases, the peak intensity and lifetime of the ionic and atomic spectral lines of nitrogen and oxygen decrease, while those of hydrogen atoms line increases. The peak time shows a positive correlation with humidity, indicating that humidity prolongs the time to reach peak intensity across all spectral lines. Humidity exhibits similar effects on both temperature and electron density. High humidity reduces their peak values and delays the time required to reach these peaks. This research can provide valuable experimental insights for the practical application of laser-induced breakdown spectroscopy technology in high humidity environments.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"303 ","pages":"Article 129476"},"PeriodicalIF":6.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146071016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"μ-LIBS imaging of archaeological ceramics: Quantification of clay fraction in provenance study","authors":"Nicolas Herreyre ,&nbsp;Valérie Thirion-Merle ,&nbsp;Loan Lemaître ,&nbsp;Anne Schmitt ,&nbsp;Christine Oberlin ,&nbsp;Clothilde Comby-Zerbino ,&nbsp;Vincent Motto-Ros","doi":"10.1016/j.talanta.2026.129452","DOIUrl":"10.1016/j.talanta.2026.129452","url":null,"abstract":"<div><div>The provenance and circulation of archaeological ceramics are key to understanding ancient societies' trade networks and cultural exchanges. However, comparing coarse and fine wares using bulk compositional analysis remains challenging due to the variable chemical contribution of temper (e.g., sand), which masks the signature of the raw clay. This study introduces a novel quantitative μ-LIBS (micro-Laser-Induced Breakdown Spectroscopy) imaging methodology to isolate and analyse the clay fraction composition of archaeological ceramics, enabling direct geochemical comparisons between tempered coarse wares and fine wares for provenance studies.</div><div>By combining multi-elemental mapping (Ca, Fe, Ti, K, Si, Al, Mg, Mn, Na, P, Zr, Rb, Sr, Ba) with calibration based on bulk X-ray fluorescence spectrometry, the method provides accurate microscale quantification. Elemental maps are segmented to extract the clay fraction composition, overcoming the limitations of traditional bulk analysis. The protocol was validated using fired briquettes with controlled sand contents and firing temperatures, confirming its accuracy and robustness.</div><div>Applied to four coarse ware specimens (mainly amphorae) from <em>Lugdunum</em> (Roman Lyon (France) during the Augustan-period, the reconstructed clay compositions were compared to a reference database of 235 contemporaneous ceramics, including coarse wares and three <em>Lugdunum</em> Terra sigillata production groups. Results reveal a shared raw clay source between calcareous amphorae and La Muette B sigillata, supporting earlier hypotheses, while other sigillata wares remain compositionally distinct. This approach significantly advances ceramic provenance studies, particularly for complex assemblages, by enabling direct comparisons between ware types previously hindered by temper variability, together with the common total bulk elemental composition measurements.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"303 ","pages":"Article 129452"},"PeriodicalIF":6.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Capillary electrophoresis in glycosaminoglycan analysis","authors":"Rachma Dessidianti ,&nbsp;Márkó Grabarics ,&nbsp;Dávid Virág ,&nbsp;Guinevere S.M. Lageveen-Kammeijer ,&nbsp;Éva Szökő ,&nbsp;Lilla Turiák","doi":"10.1016/j.talanta.2026.129429","DOIUrl":"10.1016/j.talanta.2026.129429","url":null,"abstract":"<div><div>Glycosaminoglycans (GAGs) are structurally complex, highly acidic polysaccharides that are produced by virtually all animal cells and play essential roles in cell communication, tissue organization, and disease processes. As key components of proteoglycans and as free saccharides, GAGs are abundant on cell surfaces and in the extracellular matrix, where they interact with a wide range of proteins such as growth factors and cytokines. Their interactions with proteins are fine-tuned by extensive structural variations of the polysaccharide chains, most importantly the attachment of sulfate modifications leading to distinct sulfation patterns. The resulting extraordinary structural complexity, however, poses significant challenges to the analysis of GAGs. Capillary electrophoresis (CE) offers distinct advantages for tackling these challenges, including exceptional resolution for charged analytes, low sample requirements, and compatibility with various detection methods. In this review, we highlight recent advances in the application of CE for GAG analysis, addressing key sample preparation steps, derivatization strategies, detection methods, and various CE modes to improve resolution and sensitivity. Challenges and benefits associated with coupling CE to mass spectrometry are addressed explicitly. Selected applications across the GAG families are presented to illustrate the utility of CE in biomedical and glycomic research. Finally, the strengths and current limitations of CE for the wider GAG analysis field are evaluated, and directions for further progress and future developments are outlined.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"303 ","pages":"Article 129429"},"PeriodicalIF":6.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An antifouling electrochemical biosensor based on covalent organic framework-iridium nanocomposite functionalized with designed peptide for the detection of β-Amyloid in serum","authors":"Wenqing Wang ,&nbsp;Baoping Zhu ,&nbsp;Shujie Cheng ,&nbsp;Rui Han ,&nbsp;Min Chen ,&nbsp;Xiliang Luo","doi":"10.1016/j.talanta.2026.129483","DOIUrl":"10.1016/j.talanta.2026.129483","url":null,"abstract":"<div><div>Alzheimer's disease (AD) is a neurodegenerative disorder closely associated with the aggregation of β-Amyloid (Aβ) peptides, particularly Aβ 1–42. Electrochemical biosensors hold great potential for serological Aβ 1–42 detection due to their high sensitivity and rapid response capability. However, their performances in complex matrices such as serum are compromised by biofouling and signal interference. The biosensors with functional peptide-modified interfaces, leveraging Ir–S coordination, have had improved antifouling performance and stability. Nevertheless, conventional iridium nanoparticle (IrNPs) electrodeposition often yields heterogeneous structures with poor uniformity, limiting the consistency and sensitivity of such platforms. To address this, we developed an innovative electrochemical biosensor based on a covalent organic framework (COF)-mediated interface. Using TpPa-1 COF (Tp: 1,3,5-triformylphloroglucinol; Pa: <em>p</em>-phenylenediamine) as a structural template, we achieved uniform and high-density loading of IrNPs (IrNPs@COF). The functional peptides were subsequently assembled via robust Ir–S coordination, creating a synergistic antifouling sensing platform. This biosensor enables ultrasensitive and selective detection of Aβ 1–42 in serum, demonstrating significant potential for reliable early diagnosis of AD.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"303 ","pages":"Article 129483"},"PeriodicalIF":6.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studying the capabilities of graphite furnace atomic absorption spectrometry for the discrimination of ionic copper from copper and/or copper oxide nanoparticles","authors":"Beatriz Gómez-Nieto,&nbsp;Marcela Robayo-Barragán,&nbsp;María Jesús Gismera,&nbsp;María Teresa Sevilla,&nbsp;Jesús Rodríguez Procopio","doi":"10.1016/j.talanta.2026.129459","DOIUrl":"10.1016/j.talanta.2026.129459","url":null,"abstract":"<div><div>This work explores the applicability of Graphite Furnace Atomic Absorption Spectrometry (GFAAS) for the discrimination of ionic copper (Cu²⁺) from copper and/or copper(II) oxide nanoparticles (Cu NPs and/or CuO NPs). To perform the measurements of the NPs by GFAAS, the preparation of stable suspensions from commercial solid standards of NPs with different average sizes was first evaluated. Among the evaluated dispersion media, sodium dodecyl sulphate (SDS) provided the most stable suspensions for both Cu and CuO NPs. The atomization delay (t_ad), defined as the time to reach maximum absorbance, was used as the parameter to discriminate between Cu species. Under the evaluated conditions, Cu²⁺ exhibited higher t_ad values than the nanoparticulate forms. The t_ad values remained constant for Cu concentrations ranging from 5 to 40 μg L⁻¹ for all species, demonstrating the independence of the discrimination parameter from analyte content. In addition, similar concentration calibration slopes were obtained for all species, indicating the feasibility of performing the quantification using only Cu²⁺ standards. The effects of pyrolysis and atomization temperatures, as well as the atomization heating ramp, on the resolution between the t_ad values of the Cu species were evaluated. The best time resolution for the discrimination was obtained using a pyrolysis temperature of 350 °C, a very slow atomization heating rate of 100 °C s⁻¹ and an atomization temperature of 2300 °C. Finally, the analysis of Cu²⁺ and Cu NP mixtures revealed non-additive signal profiles, suggesting possible ion - NP interactions that modify the species distribution during atomization.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"303 ","pages":"Article 129459"},"PeriodicalIF":6.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smartphone-assisted multicolor aptamer-lateral flow assay using trimetallic nanoprobes and enzyme-free signal amplification for ENR detection","authors":"Peifang Chen ,&nbsp;Mingwei Qin ,&nbsp;Yu Li ,&nbsp;Xiaodong Lu ,&nbsp;Shuo Qi ,&nbsp;Ali Raza ,&nbsp;Junsong Yang ,&nbsp;Zhouping Wang","doi":"10.1016/j.talanta.2025.129327","DOIUrl":"10.1016/j.talanta.2025.129327","url":null,"abstract":"<div><div>Nanozyme-mediated lateral flow assay (LFA) remains limited by monochromatic signals, which hampers rapid visual recognition in field testing. Intelligent detection of antibiotic is essential for ensuring food safety. Here, we proposed a reliable multicolor LFA tool for detecting enrofloxacin (ENR) residues. The strategy employed aptamer-integrated catalytic hairpin assembly (CHA) to amplify molecular recognition signals. Besides, polyA-bridged DNA strands were coupled to lychee-like AuCuPt trimetallic plasmonic nanoparticles (ACPNLs) to construct cost-effective reporting probes. During result readout, the enzyme-like activity of ACPNLs regulated the etching of Au nanostars, generating structurally distinguishable multicolor changes. Combined with smartphone software, hue values as high-precision parameters were extracted from the color wheel (0–360°). The analysis revealed a robust linear relationship between ENR concentration (0.1–600 ng/mL) and colorimetric response, achieving a detection limit of 0.06 ng/mL. In contrast to single-color LFA, the multicolor platform offered an expanded hue range and enhanced visual discernibility. Overall, this method provides a new avenue for intuitive monitoring of antibiotic, showing great promise for point-of-care food safety testing.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"302 ","pages":"Article 129327"},"PeriodicalIF":6.1,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}