{"title":"FeCuS multilayer nanoflowers loaded with N-CDs dual-mode method for the detection of uric acid and gout risk prediction with the aid of chemometrics.","authors":"Rou Cheng, Chunyan Yan, Zhengyue Xiao, Xiaomin Tang, Peng Xu, Ping Qiu","doi":"10.1016/j.talanta.2025.127700","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.127700","url":null,"abstract":"<p><p>Transition metal sulfides have attracted much attention due to their low cost, high stability, adjustable performance, diverse morphology and good catalytic activity. In this work, nitrogen-doped carbon dots (N-CDs) were loaded onto bimetallic sulfides (FeCuS) and FeCuS/N-CDs could act as catalyst and fluorescent probe, which applied to the detection of uric acid (UA) in human blood and urine using dual-model assay (colorimetry and ratiometric fluorescence). The nanozyme has excellent peroxidase-like activity and steady-state kinetic results showed that the material prepared under optimized conditions had better affinity (K<sub>m</sub> = 0.42 mM) for the substrate and faster reaction rate (V<sub>max</sub> = 14.1 × 10<sup>-8</sup> M s<sup>-1</sup>). •OH and O<sub>2</sub><sup>•-</sup> were involved in the catalytic process of o-phenylenediamine (OPD) by FeCuS/N-CDs nanozymes. A profound discussion and quantitative analysis about the sensing mechanism of UA and fluorescence quenching mechanism between FeCuS/N-CDs and diaminophenazine (DAP) was performed. According to Parker equation, the inhibition efficiency of DAP in FeCuS/N-CDs was as high as 83 % of the total inhibition efficiency, confirming that the inhibition efficiency mainly came from internal filtering effect (IFE). The detection limits of ratiometric fluorescence method and colorimetric method were as low as 0.13 μM and 0.27 μM, respectively. Finally, principal component analysis was used to successfully distinguish three groups of people (healthy people, potential people and gout patients) and the model has potential value in clinical applications.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"287 ","pages":"127700"},"PeriodicalIF":5.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
TalantaPub Date : 2025-02-04DOI: 10.1016/j.talanta.2025.127694
Lijun Han , Yalong Pan , Li Luo , Junxue Shen , Yao Yu
{"title":"Advances in fluorescent probes of non-alcoholic fatty liver disease","authors":"Lijun Han , Yalong Pan , Li Luo , Junxue Shen , Yao Yu","doi":"10.1016/j.talanta.2025.127694","DOIUrl":"10.1016/j.talanta.2025.127694","url":null,"abstract":"<div><div>Non-alcoholic fatty liver disease (NAFLD) is the predominant chronic liver disease worldwide, with 20–30 % of individuals going on to develop non-alcoholic steatohepatitis (NASH), which could result in serious complications such as fibrosis, liver cirrhosis, and hepatocellular carcinoma. Since NAFLD is reversible in its early stages, early diagnosis is necessary. By using particular structural and functional designs, fluorescent probes can be made to detect NAFLD-related chemicals or biological processes with a high degree of sensitivity and selectivity. In this work, we summarize the existing fluorescent probes for identifying biomarkers in NAFLD, including microenvironment (viscosity, polarity), ROS, RNS, RSS, metal ions, enzymes, and RNA. Furthermore, future directions are envisioned to inform the creation of more accurate and reliable fluorescent probes for NAFLD diagnosis, emphasizing the benefits and challenges of fluorescence probes.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"287 ","pages":"Article 127694"},"PeriodicalIF":5.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143349039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
TalantaPub Date : 2025-02-04DOI: 10.1016/j.talanta.2025.127693
Bakr Ahmed Taha , Zahraa Mustafa Abdulrahm , Ali J. Addie , Adawiya J. Haider , Ali Najem Alkawaz , Isam Ahmed M. Yaqoob , Norhana Arsad
{"title":"Advancing optical nanosensors with artificial intelligence: A powerful tool to identify disease-specific biomarkers in multi-omics profiling","authors":"Bakr Ahmed Taha , Zahraa Mustafa Abdulrahm , Ali J. Addie , Adawiya J. Haider , Ali Najem Alkawaz , Isam Ahmed M. Yaqoob , Norhana Arsad","doi":"10.1016/j.talanta.2025.127693","DOIUrl":"10.1016/j.talanta.2025.127693","url":null,"abstract":"<div><div>Multi-omics profiling integrates genomic, epigenomic, transcriptomic, and proteomic data, essential for understanding complex health and disease pathways. This review highlights the transformative potential of combining optical nanosensors with artificial intelligence (AI). It is possible to identify disease-specific biomarkers using real-time and sensitive molecular interactions. These technologies are precious for genetic, epigenetic, and proteomic changes critical to disease progression and treatment response. AI improves multi-omics profiling by analyzing large, diverse data sets and common patterns traditional methods overlook. Machine learning tools Biomarkers Discovery is revolutionizing, drug resistance is being understood, and medicine is being personalized as the combination of AI and nanosensors has advanced the detection of DNA methylation and proteomic signatures and improved our understanding of cancer, cardiovascular disease and vascular disease. Despite these advances, challenges still exist. Difficulties in integrating data sets, retaining sensors, and building scalable computing tools are the biggest obstacles. It also examines various solutions with advanced AI algorithms and innovations, including fabrication in nanosensor design. Moreover, it highlights the potential of nanosensor-assisted, AI-driven multi-omics profiling to revolutionize disease diagnosis and treatment. As technology advances, these tools pave the way for faster diagnosis, more accurate treatment and improved patient outcomes, offering new hope for personalized medicine.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"287 ","pages":"Article 127693"},"PeriodicalIF":5.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143286416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
TalantaPub Date : 2025-02-04DOI: 10.1016/j.talanta.2025.127692
Yuxin Wang, Yulin Wang, Jizhen Fu, Suzhen Li, Yawen Zhang, Xiaojiao Zheng, Jin Liu, Li Li, Xu Jing
{"title":"Semi-automatic emulsification liquid-liquid microextraction with deep eutectic solvent for the determination of strobilurin fungicides in food samples.","authors":"Yuxin Wang, Yulin Wang, Jizhen Fu, Suzhen Li, Yawen Zhang, Xiaojiao Zheng, Jin Liu, Li Li, Xu Jing","doi":"10.1016/j.talanta.2025.127692","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.127692","url":null,"abstract":"<p><p>In this study, a rapid and simple semi-automatic emulsification liquid-liquid microextraction technique based on deep eutectic solvents was developed for determining strobilurin fungicides in food samples using high-performance liquid chromatography. Novel deep eutectic solvents formed as extractants by combining quaternary phosphates and fatty acids, eliminating the need for toxic solvents in liquid-phase microextraction. The extraction process was facilitated by an electric micropipette, which emulsified and injected the deep eutectic solvent-water mixture directly into the sample. The semi-automated approach enhanced extraction speed and efficiency while minimizing manual error. The sample and deep eutectic solvent mixture were emulsified immediately and separated within 15 min of standing. Only an electronic micropipette was used to achieve extraction and separation. The method demonstrated a linear range of 2-200 μg L<sup>-1</sup> with R<sup>2</sup> > 0.996 and a limit of detection of 0.6 μg L<sup>-1</sup>. Recovery ranged from 73.0 % to 100.1 %, with relative standard deviations from 0.4 % to 6.1 %. The greenness of the method was validated through multiple assessment tools, including the Green Analytical Procedure Index, Analytical GREEnness metric for sample preparation, and Sample Preparation Metric of Sustainability. The emulsification liquid-liquid microextraction procedure, based on innovative solvents and electric micropipette technology, proved successful for application in water, juice, and vinegar samples and showed potential for broader use in pesticide residue analysis in food.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"287 ","pages":"127692"},"PeriodicalIF":5.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
TalantaPub Date : 2025-02-04DOI: 10.1016/j.talanta.2025.127676
Daiane Dulcileia Moraes de Paula , Ricky Cássio Santos da Silva , Laíse Aparecida Fonseca Dinali , Camilla Fonseca Silva , Marcone Augusto Leal de Oliveira , Arnaldo César Pereira , Keyller Bastos Borges
{"title":"Magnetic solid phase extraction based on restricted access molecularly imprinted polymer with dually coated for enantioselective determination of tramadol in human plasma by capillary electrophoresis with ultraviolet detection","authors":"Daiane Dulcileia Moraes de Paula , Ricky Cássio Santos da Silva , Laíse Aparecida Fonseca Dinali , Camilla Fonseca Silva , Marcone Augusto Leal de Oliveira , Arnaldo César Pereira , Keyller Bastos Borges","doi":"10.1016/j.talanta.2025.127676","DOIUrl":"10.1016/j.talanta.2025.127676","url":null,"abstract":"<div><div>A restricted-access magnetic molecularly imprinted polymer with dually coated of hydrophilic monomer and bovine serum albumin was synthesized, properly characterized by different techniques, and used as adsorbent in Magnetic Solid Phase Extraction (MSPE). Furthermore, a simple and efficient method employing capillary electrophoresis with ultraviolet detection was developed and validated for the enantioselective determination of tramadol (TRM) in human plasma. The optimized conditions were 25 mM phosphate background electrolyte at pH 9.05 using 0.01 g of sulfated-β-cyclodextrin as chiral selector, hydrodynamic injection at 40 mbar for 4 s, voltage at 10 kV, temperature of 25 °C, and a fused silica capillary with an effective length of 50 cm. In these conditions, (−)-(1<em>S</em>,2<em>S</em>)-TRM exhibited a migration time of 8.48 min and (+)-(1<em>R</em>,2<em>R</em>)-TRM of 9.50 min. Several factors affecting the MSPE were optimized, achieving extraction recoveries/relative standard deviation of 99.6 ± 8.1 % by means of 100 μL of human plasma at pH 8, 1000 μL of acetonitrile as eluent, 20 mg of adsorbent, 200 μL ultrapure water as washing solvent, and 60 s of stirring. The method was linear (range of 100–3000 ng mL⁻<sup>1</sup>), selective, and accurate, with a limit of quantification and detection of 100 and 50 ng mL⁻<sup>1</sup>, respectively, for both enantiomers, allowing their determination in real human plasma samples. This method presents an important alternative for monitoring athletes and in forensic applications.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"288 ","pages":"Article 127676"},"PeriodicalIF":5.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
TalantaPub Date : 2025-02-04DOI: 10.1016/j.talanta.2025.127670
Jiqiang Wang , Hainan Zhao , Yekuan Zhou , Yongda Yan , Zhuo Fang , Yanquan Geng
{"title":"Electrochemical sensing of Hg(II) ions based on ultramicrotome-crafted strip ultramicroelectrode","authors":"Jiqiang Wang , Hainan Zhao , Yekuan Zhou , Yongda Yan , Zhuo Fang , Yanquan Geng","doi":"10.1016/j.talanta.2025.127670","DOIUrl":"10.1016/j.talanta.2025.127670","url":null,"abstract":"<div><div>The presence of heavy metal ions in the biosphere constitutes a significant source of pollution, posing severe threats to both human health and the environment. Thus, the accurate detection of heavy metal ions assumes paramount importance. The present study involves the preparation of electrochemical sensors based on strip ultramicroelectrode, enabling the detection of Hg<sup>2+</sup>. The electrochemical performance of strip ultramicroelectrode is characterized firstly. The Au strip ultramicroelectrode demonstrates exceptional suitability for the detection of Hg<sup>2+</sup>. Moreover, the acetate buffer is confirmed as an advantageous detection medium for Hg<sup>2+</sup> owing to its slight influence on the result. The electrochemical detection parameters of the strip ultramicroelectrode, such as the pH value of the acetate buffer, enrichment potential, and enrichment time, have been optimized. The prepared electrochemical sensors based on strip ultramicroelectrode are utilized to detect the Hg<sup>2+</sup> in tap water, snow melt water and bottled water. The detection limitation exceeds the thresholds established by the drinking water quality standards of China, the World Health Organization, and the European Union. The sensor prepared based on the strip ultramicroelectrode has exceptional accuracy, reliability, and practical applicability.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"287 ","pages":"Article 127670"},"PeriodicalIF":5.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143179434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
TalantaPub Date : 2025-02-04DOI: 10.1016/j.talanta.2025.127664
Beata Krasnodębska-Ostręga, Jakub Warowny, Monika Sadowska
{"title":"Sensitive method for titanium determination in soil extract using adsorptive stripping voltammetry","authors":"Beata Krasnodębska-Ostręga, Jakub Warowny, Monika Sadowska","doi":"10.1016/j.talanta.2025.127664","DOIUrl":"10.1016/j.talanta.2025.127664","url":null,"abstract":"<div><div>Wide application of TiO<sub>2</sub> results in contamination of the environment, and may cause adverse changes in the soil. Monitoring of soil for pollution with both solid and ionic (mobile) forms of Ti seems to be a need. Therefore, it is necessary to develop an alternative method to ICP-MS for determining ionic Ti at low concentration. Electrochemistry is particularly promising, as only the ionic form is determined, and with high precision. Adsorptive stripping voltammetry with differential pulse mode, utilizing complexation with mandelic acid supported by the catalytic effect of chlorate (V) ions, is presented here for determination of Ti in unmodified extract of soil rich in organic matter. The proposed procedure allows to detect 0.01 ng mL<sup>−1</sup> in voltammetric cell, which gives 3 ng mL<sup>−1</sup> for peat soil extracts (t<sub>d</sub> = 240 s) with precision <1.5%. The studies indicated that 0.3 ng of Ti(IV) in cell is quantified with 100–101% recovery. The procedure optimized for such a challenging matrix can be included in complex studies of the content of ionic and solid forms of titanium compounds in soils.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"288 ","pages":"Article 127664"},"PeriodicalIF":5.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143376887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Near-field and far-field competitive couplings between plasmonic nanodisk array and nanoparticles for rapid and facile heparin assay.","authors":"Shuwen Chu, Huizhen Yuan, Yuzhang Liang, Cheng Yang, Qiang Liu, Wei Peng","doi":"10.1016/j.talanta.2025.127690","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.127690","url":null,"abstract":"<p><p>Plasmonic biosensors hold an enticing prospect for drug testing and disease diagnostics as they have demonstrated impressive superiority in ultrasensitive and label-free detection. In this paper, we demonstrate a plasmonic sensing strategy for the heparin assay by leveraging near-field and far-field competitive couplings between gold (Au) nanoparticles (NPs) and nanodisk (ND) array. Specifically, the near-field coupling of the ND array and Au NPs binding to its surface results in a spectral redshift. Meanwhile, the far-field coupling of dispersed Au NPs in mixed solution and ND array induces a spectral blueshift. As a result, heparin concentration-dependent near-field and far-field competitive couplings determine the direction and amount of the spectral shift. Compared with existing detection technologies, this sensing strategy also presents a balance point, enabling rapid assessment of heparin dosage safety. Additionally, an exceptionally wide dynamic range of 10<sup>-4</sup> μg/mL to 10<sup>3</sup> μg/mL, a low detection limit of 29 pg/mL, and excellent selectivity are demonstrated. The analysis of heparin in serum further underscores this assay approach's potential for advancing disease diagnosis and therapeutic monitoring at the point of care.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"287 ","pages":"127690"},"PeriodicalIF":5.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
TalantaPub Date : 2025-02-03DOI: 10.1016/j.talanta.2025.127687
Faezeh Ghorbanizamani , Hichem Moulahoum , Suna Timur
{"title":"MXene-poly(propylene carbonate) nanofiber network-based modification of SPE interfaces for electrochemical immuno-sensing of synthetic cannabinoid","authors":"Faezeh Ghorbanizamani , Hichem Moulahoum , Suna Timur","doi":"10.1016/j.talanta.2025.127687","DOIUrl":"10.1016/j.talanta.2025.127687","url":null,"abstract":"<div><div>The decriminalization and legalization of cannabis have increased its consumption and the need for effective monitoring methods. Synthetic cannabinoids, while chemically distinct from natural cannabinoids like THC, can be more potent and cause severe adverse effects, often evading detection by traditional drug tests. Thus, there is a critical need for new biosensors that offer rapid, sensitive, and reliable detection of these compounds in biological samples. This study presents a novel electrochemical immunosensor based on aminated MXene integrated with poly(propylene carbonate) (PPC) nanofibers and monoclonal antibodies designed to enhance the detection of synthetic cannabinoids. The PPC/MXene-NH₂ nanofibers, electrospun onto screen-printed electrodes (SPEs), provide increased surface area and high sensitivity, stability, and selectivity. The biosensor achieved a wide detection range of 0.6–2000 ng/mL in saliva, a low limit of detection (LOD) of 0.66 ng/mL, and demonstrated excellent specificity. It showed high repeatability and reproducibility with minimal signal degradation, with vacuum-sealed storage proving to significantly extend sensor stability over time. These results highlight the potential of MXene-enhanced PPC nanofiber immunosensors as sensitive, selective, and portable tools for rapid detection of synthetic cannabinoids in clinical and forensic settings.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"287 ","pages":"Article 127687"},"PeriodicalIF":5.6,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143179437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
TalantaPub Date : 2025-02-03DOI: 10.1016/j.talanta.2025.127679
Ruifang Liu, Zhenting Wu, Qiang Li, Sara Shamim, Long Ba
{"title":"Fully printed field-effect transistor humidity sensor with chitosan/polyvinyl alcohol/nano carbon powder for enhanced moisture sensitivity.","authors":"Ruifang Liu, Zhenting Wu, Qiang Li, Sara Shamim, Long Ba","doi":"10.1016/j.talanta.2025.127679","DOIUrl":"https://doi.org/10.1016/j.talanta.2025.127679","url":null,"abstract":"<p><p>With the advancement of flexible electronics, the demand for low-cost, high-performance flexible humidity sensors for wearable devices has increased significantly. However, commercial humidity sensors require complex preparation methods and are expensive. Therefore, we report polyvinyl alcohol/chitosan/nano carbon powder (PVA/CS/NCP) humidity-sensitive composite materials, which were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and contact angle measurements. A resistive humidity sensor was fabricated using screen printing, and the device showed a good response at 33%RH-98%RH humidity, and at 98 % RH, the sensor achieved a response of 1.74. A fully printed field-effect transistor (FET) humidity sensor was prepared by integrating an ion gel transistor with a CS/PVA/NCP humidity-sensitive resistor to improve the response. The comparison reveals a significant improvement in the FET humidity sensor's response, reaching 6.27 at 98 % RH. In addition, both types of sensors exhibit less hysteresis and good repeatability. Lastly, we tested the constructed humidity sensors under non-contact and variable breathing conditions, laying the groundwork for future wearable applications.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"287 ","pages":"127679"},"PeriodicalIF":5.6,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}