Talanta最新文献_第6页

Advances in nanoparticle-enhanced paper sensor for detecting toxic metals in water

IF 5.6 1区化学

Talanta Pub Date : 2025-04-14 DOI: 10.1016/j.talanta.2025.128146

Marzieh Sadat Hosseini , Rajiv Padhye , Xin Wang , Shadi Houshyar

{"title":"Advances in nanoparticle-enhanced paper sensor for detecting toxic metals in water","authors":"Marzieh Sadat Hosseini , Rajiv Padhye , Xin Wang , Shadi Houshyar","doi":"10.1016/j.talanta.2025.128146","DOIUrl":"10.1016/j.talanta.2025.128146","url":null,"abstract":"<div><div>Toxic metals in water pose a serious threat to public health and the environment, especially in regions with limited access to advanced laboratory infrastructure. Traditional methods for detecting toxic metals, such as atomic absorption spectrometry (AAS) and inductively coupled plasma mass spectrometry (ICP-MS), are accurate but expensive, complex, and unsuitable for on-site use. In contrast, paper-based analytical devices (PADs) offer a low-cost, and user-friendly alternative, especially in resource-limited areas. Recent advancements have significantly improved PAD performance, especially through the integration of nanoparticles and the use of enhanced colorimetric and electrochemical detection methods. These improvements have enabled faster, more sensitive detection while maintaining simplicity and field readiness. This review explores key advancements in PAD technology from 2015 to 2025 including advances in sensitivity, nanoparticle functionalization, and smartphone-based readouts. Unlike previous reviews, this study presents a comparative analysis of PAD detection mechanisms, evaluates commercialization and regulatory challenges, and explores emerging trends such as smartphone integration and microextraction techniques. By addressing these aspects, this review highlights key advancements and optimization strategies to enhance the stability, selectivity, and practical implementation of PADs for water quality monitoring.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128146"},"PeriodicalIF":5.6,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical immunoplatform for the quantification of epithelial extracellular vesicles applied to prostate cancer diagnosis

IF 5.6 1区化学

Talanta Pub Date : 2025-04-13 DOI: 10.1016/j.talanta.2025.128130

Emiliano Felici , Coral González-Martínez , Teresa Valero Griñán , Sheila Gato-Zambrano , Sirley V. Pereira , Martín A. Fernández-Baldo , Francisco G. Ortega-Sanchez

{"title":"Electrochemical immunoplatform for the quantification of epithelial extracellular vesicles applied to prostate cancer diagnosis","authors":"Emiliano Felici , Coral González-Martínez , Teresa Valero Griñán , Sheila Gato-Zambrano , Sirley V. Pereira , Martín A. Fernández-Baldo , Francisco G. Ortega-Sanchez","doi":"10.1016/j.talanta.2025.128130","DOIUrl":"10.1016/j.talanta.2025.128130","url":null,"abstract":"<div><div>Prostate cancer (PCa) is the second most commonly diagnosed cancer in men worldwide, and its early detection is critical for improving patient outcomes through timely and effective treatment. In this work, we present the first electrochemical immunoplatform based on magnetic microbeads (MBs) for the determination of epithelial extracellular vesicles (EpEVs), which are emerging as promising biomarkers for PCa diagnosis and prognosis. The immunoplatform employs MBs functionalized with anti-EpCAM antibodies to selectively capture EpEVs, forming sandwich-type immune complexes that are detected via amperometry at disposable screen-printed carbon electrodes. The method demonstrated a detection limit of 0.4 ng μL<sup>−1</sup> of EpEVs obtained from PC-3 cell line's culture, excellent reproducibility (coefficient of variation <5 %), and high selectivity against potential interferences. Comparative analysis with colorimetric immune-magnet ELISA test showed a strong correlation between the two methods, confirming the reliability of the proposed approach. Furthermore, the electrochemical platform provided better precision and a lower limit of detection than the immune magnet ELISA method, indicating its superior analytical performance. Clinical validation using patient samples revealed that the combination of EpEV detection with PSA levels significantly improves the sensitivity and specificity of PCa diagnosis. This novel immunoplatform represents a promising analytical tool for early detection and monitoring of PCa, with potential applications in personalized cancer management.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128130"},"PeriodicalIF":5.6,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Waveguide microwave gas sensor based on monolithic In2O3 for enhanced ammonia detection

IF 5.6 1区化学

Talanta Pub Date : 2025-04-13 DOI: 10.1016/j.talanta.2025.128122

Ling Gao , Juhua Xu , Xianwang Yang , Chang Xu , Xiaolong Wang , Quan Jin

{"title":"Waveguide microwave gas sensor based on monolithic In2O3 for enhanced ammonia detection","authors":"Ling Gao , Juhua Xu , Xianwang Yang , Chang Xu , Xiaolong Wang , Quan Jin","doi":"10.1016/j.talanta.2025.128122","DOIUrl":"10.1016/j.talanta.2025.128122","url":null,"abstract":"<div><div>For commonly used chemical resistance sensors, achieving room-temperature detection often results in reduced performance. Microwave gas sensors have been rapidly expanding in recent years, attributed to their advantages of room-temperature operation and low power consumption. Waveguide, as a three-dimensional microwave circuit with separated electric and magnetic field distributions, resulting in high quality factor, is expected to significantly enhance the sensitivity of microwave sensors. Additionally, the hierarchical porous structure of monolithic In<sub>2</sub>O<sub>3</sub> facilitates gas diffusion, further enhancing sensing performance. Herein, a microwave gas sensor is designed by applying porous monolithic In<sub>2</sub>O<sub>3</sub> and waveguide resonator. By adjusting the content of the polymer PVP, In<sub>2</sub>O<sub>3</sub> with different pore sizes is synthesized in which hierarchical porous In<sub>2</sub>O<sub>3</sub> sample with a PVP content of 3.0 g (3.0-HPS In<sub>2</sub>O<sub>3</sub>) exhibits the best NH<sub>3</sub> sensing properties, including a wide concentration range (0.01–2000 ppm), a low limit of detection (LOD) of 7 ppb, excellent selectivity, good moisture resistance, and long-term stability. This study offers a promising approach for the development of room-temperature ammonia gas sensors with an extended detection range and has preliminarily explored the influence of pore sizes on gas sensing performance.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128122"},"PeriodicalIF":5.6,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantum dots encoded superparamagnetic micron-particles based on layer-by-layer assembly for multiplexed nucleic acid detection

IF 5.6 1区化学

Talanta Pub Date : 2025-04-13 DOI: 10.1016/j.talanta.2025.128109

Xiaoshuang Zhao , Jieying Zhang , Yifan Chen , Ziting Chen , Zhe Liu , Yi Xu , Xingjun Zhu , Yang Li , Xianqiang Mi

{"title":"Quantum dots encoded superparamagnetic micron-particles based on layer-by-layer assembly for multiplexed nucleic acid detection","authors":"Xiaoshuang Zhao , Jieying Zhang , Yifan Chen , Ziting Chen , Zhe Liu , Yi Xu , Xingjun Zhu , Yang Li , Xianqiang Mi","doi":"10.1016/j.talanta.2025.128109","DOIUrl":"10.1016/j.talanta.2025.128109","url":null,"abstract":"<div><div>With the rapid development of precise medicine, microbeads-based fluorescence bio-coding technology for multiplexed detection has attracted increasing attentions. However, traditional multiplexed bio-analysis could not meet the demand for multiplexed detection due to the limitations of labeling dyes and microscope channels. Here, a novel fluorescence encoding strategy was proposed by using multi-color quantum dots (QDs) acted as fluorescence tags and micron sized superparamagnetic particle acted as encoding carrier. By adjusting the color and number of labeled QDs, fluorescence encoded superparamagnetic particles (FESPs) with distinct fluorescence colors and intensities were constructed. The FESPs were prepared by metal coordination-based layer-by-layer assembly with excellent binding effect. By binding DNA capture oligonucleotides, FESP probes were constructed for multiplexed detection of miRNA-21, miRNA-122 and miRNA-130b with excellent specificity. Moreover, the miRNA targets could be easily separated within 5 s originated from the excellent superparamagnetism, enabling great simplified bio-analysis process. The results demonstrated here will provide opportunities to realize the full potentials of fluorescence bio-coding in biomedical detection and diagnosis.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128109"},"PeriodicalIF":5.6,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143825531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of universal isotachophoresis – capillary zone electrophoresis method for trace determination of bromide in complex ionogenic samples 开发用于痕量测定复杂离子源样品中溴化物的通用等位电泳-毛细管区带电泳方法

IF 5.6 1区化学

Talanta Pub Date : 2025-04-11 DOI: 10.1016/j.talanta.2025.128113

Marián Masár, Jasna Hradski, Roman Szucs

{"title":"Development of universal isotachophoresis – capillary zone electrophoresis method for trace determination of bromide in complex ionogenic samples","authors":"Marián Masár, Jasna Hradski, Roman Szucs","doi":"10.1016/j.talanta.2025.128113","DOIUrl":"10.1016/j.talanta.2025.128113","url":null,"abstract":"<div><div>Trace determination of bromide in water samples and high-purity chemicals was accomplished by capillary zone electrophoresis (CZE) with online isotachophoresis (ITP) sample pretreatment and photometric detection at 200 nm. The adverse effect of bromide on human health necessitates its monitoring in drinking water. Bromide is also a precursor of bromate, a carcinogenic by-product of water disinfection that can be formed in drinking water during ozonation (oxidation of bromide to bromate). ITP-CZE separations were performed at acidic pH (2.7) as this facilitates high selectivity of the separation system. Addition of the zwitterionic surfactant <em>N</em>-dodecyl-<em>N</em>,<em>N</em>-dimethyl-3-ammonio-1-propanesulfonate to the leading electrolyte enhanced the separation of bromide from anionic macrocomponents in drinking water. The first separation step, ITP, served as a very efficient sample clean-up. Linear response was observed in the presence and absence of matrix in the concentration range 1–50 μg/L. ITP-CZE separations were characterized by very good repeatability of migration times (up to 0.4 % RSD) as well as peak areas (up to 3.7 % RSD) of bromide. The achieved limit of detection for bromide was 0.3 μg/L in the presence of matrix. To assess the practical applicability of the developed test procedure, samples of mineral and drinking water, as well as highly pure chloride salts, were analyzed. Recoveries of bromide in the analyzed samples were in the range of 98–103 %. The developed ITP-CZE method can be used for highly selective determination of trace concentrations of bromide present in ionogenic samples.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128113"},"PeriodicalIF":5.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143825534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

To take unseen: direct gel-supported liquid extraction for multi-technique characterization of organic colourants in paint layers 未曾谋面：直接凝胶支撑液体萃取用于油漆层中有机着色剂的多技术表征

IF 5.6 1区化学

Talanta Pub Date : 2025-04-11 DOI: 10.1016/j.talanta.2025.128041

Adele Bosi , Alessandro Ciccola , Ilaria Serafini , Sanne Berbers , Art Néss Proano Gaibor , Elke Cwiertnia , Paolo Postorino , Gabriele Favero , Maarten R. van Bommel

{"title":"To take unseen: direct gel-supported liquid extraction for multi-technique characterization of organic colourants in paint layers","authors":"Adele Bosi , Alessandro Ciccola , Ilaria Serafini , Sanne Berbers , Art Néss Proano Gaibor , Elke Cwiertnia , Paolo Postorino , Gabriele Favero , Maarten R. van Bommel","doi":"10.1016/j.talanta.2025.128041","DOIUrl":"10.1016/j.talanta.2025.128041","url":null,"abstract":"<div><div>The study of organic colourants employed in artworks is a fundamental topic for history and conservation research; however, the most critical aspect in such matter arises from the necessity of sampling. Instead of binding media and inorganic components, natural organic colourants often exhibit weak signals during non-invasive analyses, which can be easily masked in complex mixtures, such as paint layers. To overcome this problem, the preferred approach is to take a sample, extract the colourants and analyse them using specific analytical techniques. The proposed method of direct agar gel-supported liquid extraction, performed using a Pasteur pipette tip, offers a promising solution to this challenge. By extracting colourants without the need for paint sample removal, it minimises visible impact on the artwork while still providing sufficient material for spectroscopic and mass spectrometric characterization. The experimental approach, which involved mock-up of mixing different organic and inorganic pigments with different binders and subjecting them to artificial ageing, simulates real-world complex matrices and assesses the effectiveness of the extraction method. Photomicrographs were used to document the procedure's visible impact. Mass spectrometry and surface-enhanced Raman scattering spectroscopy, the techniques of choice for invasive analysis of organic colourants, were used on the analytes extracted from the gel. The method application on paint patches from historical catalogues, housed in the <em>Stiftung Preußischer Kulturbesitz</em> collection, adds practical relevance to the study and demonstrates the applicability of the technique to authentic artworks. The procedure enabled the identification of natural and synthetic colourants without compromising the integrity of the paint systems.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128041"},"PeriodicalIF":5.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143825535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of metabolic pathways of racemic ketamine and its (S)-enantiomer in rat blood plasma using CE-ESI/MS with partial filling of dual chiral selector system 利用部分填充双手性选择器系统的 CE-ESI/MS 研究外消旋氯胺酮及其 (S) 对映异构体在大鼠血浆中的代谢途径

IF 5.6 1区化学

Talanta Pub Date : 2025-04-11 DOI: 10.1016/j.talanta.2025.128129

Renáta Konášová , Dušan Koval , Petr Tůma , Šimon Vaculín , Václav Kašička

{"title":"Study of metabolic pathways of racemic ketamine and its (S)-enantiomer in rat blood plasma using CE-ESI/MS with partial filling of dual chiral selector system","authors":"Renáta Konášová , Dušan Koval , Petr Tůma , Šimon Vaculín , Václav Kašička","doi":"10.1016/j.talanta.2025.128129","DOIUrl":"10.1016/j.talanta.2025.128129","url":null,"abstract":"<div><div>Ketamine is a chiral drug used as anesthetic, analgesic and antidepressant. Its enantiomers and stereoisomers of its metabolites show different pharmacological and behavioral effects. To study the ketamine metabolic pathway and investigate these effects, highly sensitive and enantioselective methods are required. For that reason, in this study, a new CE method using a partial filling dual chiral selector system and ESI-MS detection has been developed and applied for separation and quantification of enantiomers of ketamine and its main metabolites, norketamine, hydroxynorketamine and dehydronorketamine, extracted by dichloromethane from the blood plasma of laboratory rats. The dual chiral selector system consisting of two zones of highly sulfated β-cyclodextrin (30 mg mL<sup>−1</sup>) and highly sulfated γ-cyclodextrin (10 mg mL<sup>−1</sup>) was introduced consecutively near the capillary outlet end. Both chiral selectors were dissolved in the background electrolyte composed of 10 mM ammonium hydroxide, 104 mM acetic acid, 10 % (v/v) ethanol, pH∗ 3.75. This system enabled enantioseparation of ketamine and its metabolites within a single CE run. High resolutions (3.99–17.61) of enantiomers of all above four analytes within a short time (11 min) were achieved in the fused silica capillary covalently coated with weakly negatively charged polyanionic copolymer (poly(acrylamide-<em>co</em>-sodium-2-acrylamido-2-methylpropanesulfonate), PAMAMPS). This coating minimized analyte sorption to the capillary and provided good repeatability of migration times. The limits of detection and quantification of the above analytes were in the range 108–238 nM and 361–792 nM, respectively. The method was linear within wide concentration range of 0.1–200 μM and the recovery was 91.3–105 %.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128129"},"PeriodicalIF":5.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Finger-actuated microfluidic chip integrated with visual immunoassay for ultrasensitive detection of PSA in whole blood

IF 5.6 1区化学

Talanta Pub Date : 2025-04-10 DOI: 10.1016/j.talanta.2025.128127

Chaoshan Zhao , Junju Wang , Liwei Hou , Hong He , Chuang Ge , Yuping Yang , Li Wang , Yi Xu , Shunbo Li

{"title":"Finger-actuated microfluidic chip integrated with visual immunoassay for ultrasensitive detection of PSA in whole blood","authors":"Chaoshan Zhao , Junju Wang , Liwei Hou , Hong He , Chuang Ge , Yuping Yang , Li Wang , Yi Xu , Shunbo Li","doi":"10.1016/j.talanta.2025.128127","DOIUrl":"10.1016/j.talanta.2025.128127","url":null,"abstract":"<div><div>Cumbersome preprocessing and specialized manual operations in clinical blood samples remain a significant challenge for achieving high sensitivity and accurate quantification in point-of-care testing. In this paper, a finger-driven integrated microfluidic chip based on visualization of single nanoparticle scattering was proposed for the detection of prostate-specific antigen (PSA) in the whole blood. To control on-chip fluid, a finger-driven module based on a Tesla valve was designed to unidirectionally regulate fluid mixing and separation in the microchannel. In addition, a membrane separation unit was designed to efficiently separate blood cells and serum, reducing interference from blood cells in the detection process. For quantitative PSA concentration detection, a Multi-functional core-satellite magnetic probe was constructed by using the principle of complementary base pairing of ligands on the surface of gold nanoparticles and magnetic beads. In the presence of target PSA, the constructed core-satellite nanostructure was decomposed, producing a characteristic fluorescence signal and releasing gold nanoparticles with green scattering spots under dark-field microscopy. By correlating the concentration with the number of green scattering spots, cancer risk levels were displayed intuitively using a traffic light system. This biosensor achieves an ultra-low detection limit of 0.5 pg/mL for PSA. Due to the ultra-sensitive ability in detection, the monitoring of PSA concentrations for patients during treatment was also demonstrated. Compared with other methods, this proposed microfluidic assay technology has the advantages of small sample volume, minimal operation, high sensitivity and accuracy. Overall, this biosensor provides a new approach for cancer recurrence monitoring and early diagnosis.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128127"},"PeriodicalIF":5.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Porphyrinic metal-organic framework PCN-224 supported Prussian blue enables selective detection of casein and phytic acid

IF 5.6 1区化学

Talanta Pub Date : 2025-04-10 DOI: 10.1016/j.talanta.2025.128121

Zhiqiang Zhou, Xiao Zhang, Wenting Chen, Zhaowei Liang, Zihan Zhang, Liyun Yang

{"title":"Porphyrinic metal-organic framework PCN-224 supported Prussian blue enables selective detection of casein and phytic acid","authors":"Zhiqiang Zhou, Xiao Zhang, Wenting Chen, Zhaowei Liang, Zihan Zhang, Liyun Yang","doi":"10.1016/j.talanta.2025.128121","DOIUrl":"10.1016/j.talanta.2025.128121","url":null,"abstract":"<div><div>Monitoring casein and phytic acid content is of great significance for food safety and human health. In this paper, porphyrinic metal-organic framework PCN-224 supported Prussian blue (PCN-224@PB) nanoprobe was constructed by in-situ growth of PB on PCN-224 layer. The supported PCN-224 not only reduces the size and improves the dispersity of PB, but also provides specific affinity for casein and phytic acid. Based on the formation of Zr-OP structure, the peroxidase (POD)-like activity of PCN-224@PB is inhibited when encountering casein. In the presence of phytic acid, the deposited PB is decomposed, thus recovering the fluorescence of PCN-224 quenched by PB. The constructed nanoprobe exhibits high sensitivity with a limit of detection of 0.25 μg/mL for casein and 0.18 μM for phytic acid detection, respectively. In addition, PCN-224@PB shows excellent sensing performance in milk, beverage, corn and cells samples, with casein and phytic acid recoveries ranging from 94.30 % to 103.20 %, further demonstrating its feasibility in real sample analysis.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128121"},"PeriodicalIF":5.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dummy molecularly imprinted polymer nanochannel sensor for ultrasensitive detection of aniline compounds

IF 5.6 1区化学

Talanta Pub Date : 2025-04-10 DOI: 10.1016/j.talanta.2025.128123

Ya Sun , Ziwen Zhao , Jie Zhao , Lide Hu , Yawei Shi , Mengqi Li

{"title":"Dummy molecularly imprinted polymer nanochannel sensor for ultrasensitive detection of aniline compounds","authors":"Ya Sun , Ziwen Zhao , Jie Zhao , Lide Hu , Yawei Shi , Mengqi Li","doi":"10.1016/j.talanta.2025.128123","DOIUrl":"10.1016/j.talanta.2025.128123","url":null,"abstract":"<div><div>Aniline pollutants can cause great harm to human health and the ecosystem, while rapid and selective quantification of aniline compounds in environment samples at trace levels is a highly complex target. In this study, a novel, efficient nanochannel sensor based on dummy molecularly imprinted polymer (DMIP) was fabricated. The sensor works on the principle of the ion current rectification across the asymmetric charged nanoporous capillary. With the help of the electric-concentration multi-field coupling model and controlled experiments, the ion distribution and transport in the nanoporous capillary. and the key influencing factors were examined for optimization of the sensor. At the concentration of 1 nmol/L ∼0.1 mmol/L, the rectification ratio of the nanosensor and logarithm aniline concentration exhibited a good linear relationship with the limit of detection of 0.2 nmol/L. The concentration of anilines in the real seawater sample was tested with the DMIP nanochannel sensor, and the average recovery rate was 88.31 %. The prepared DMIP nanochannel based sensor has established itself a promising method for trace aniline detection in real environmental samples, with the advantages of low cost, small size, simple operation, high accuracy and excellent reproducibility.</div></div>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"293 ","pages":"Article 128123"},"PeriodicalIF":5.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0