Microchemical Journal最新文献

筛选
英文 中文
Detecting C-peptide using biosensors for diagnosis and monitoring of disease 使用生物传感器检测 C 肽,用于诊断和监测疾病
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-13 DOI: 10.1016/j.microc.2024.111922
Zahra Jamalizadeh Bahaabadi , Prashant Kesharwani , Amirhossein Sahebkar
{"title":"Detecting C-peptide using biosensors for diagnosis and monitoring of disease","authors":"Zahra Jamalizadeh Bahaabadi ,&nbsp;Prashant Kesharwani ,&nbsp;Amirhossein Sahebkar","doi":"10.1016/j.microc.2024.111922","DOIUrl":"10.1016/j.microc.2024.111922","url":null,"abstract":"<div><div>The connecting peptide (C-peptide) is a short polypeptide that connects the A-chain to the B-chain in the proinsulin molecule. This biomarker is secreted into the blood circulation in the same amount as insulin and has a longer half-life than it. Measuring blood serum levels of C-peptide can be used to distinguish between different diabetes types. Also, the amount of C-peptide in body fluids as an indicator has been used to evaluate pancreatic beta‐cell function. However, a reliable and fast method is essential to quantify the amount of C-peptide in biological fluids and its significance in the control and diagnosis of disease. Over the years, several studies have used biosensors to detect C-peptide levels in real samples. These studies focused on speeding up detection and creating novel detection techniques. Biosensor-based methods can potentially improve the diagnosis and monitoring of diabetes. This review aims to provide a general overview of the various C-peptide biosensors in relation to their detection limit and potential point-of-care uses.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111922"},"PeriodicalIF":4.9,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of new emerging biosensors based on bacteria-imprinted polymers towards pathogenic bacteria: Promising new tools for selective detection 基于细菌印迹聚合物的新兴病原菌生物传感器综述:有望用于选择性检测的新工具
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-12 DOI: 10.1016/j.microc.2024.111918
Chou-Yi Hsu , Jasur Alimdjanovich Rizaev , Harikumar Pallathadka , Sofiene Mansouri , Dmitry Olegovich Bokov , Snehlata Sharma , Gulshan Rathore , Pranchal Rajput , Yasser Fakri Mustafa , Munther Kadhim Abosaoda
{"title":"A review of new emerging biosensors based on bacteria-imprinted polymers towards pathogenic bacteria: Promising new tools for selective detection","authors":"Chou-Yi Hsu ,&nbsp;Jasur Alimdjanovich Rizaev ,&nbsp;Harikumar Pallathadka ,&nbsp;Sofiene Mansouri ,&nbsp;Dmitry Olegovich Bokov ,&nbsp;Snehlata Sharma ,&nbsp;Gulshan Rathore ,&nbsp;Pranchal Rajput ,&nbsp;Yasser Fakri Mustafa ,&nbsp;Munther Kadhim Abosaoda","doi":"10.1016/j.microc.2024.111918","DOIUrl":"10.1016/j.microc.2024.111918","url":null,"abstract":"<div><div>The spread of pathogenic bacteria in the environment, as a significant global issue, causes a substantial threat to human health, damaging economic development. Indeed, the development of sensitive and selective sensing approaches for detection of pathogenic bacteria is essential to prevent and treating infections. In this regard, biosensors as efficient analytical methods can play an important role. Importantly, exploiting of novel strategy can improve the performance of these biosensing platforms. Among different types, molecularly imprinted polymers (MIPs), as artificial receptors, that are developed to selective and sensitive biosensors. The distinct complementary cavities in these synthetic polymers contribute to their unique characteristics, as they are specifically tailored to their respective templates. Notably, bacteria-imprinted polymers (BIPs), as an important and novel member of MIPs, attracted considerable attention for different bacteria detection due to many cavities complementary to their bacteria. These novel probes can efficiently isolate various bacteria from wide range of samples such as food, water, or biological fluids due to the high affinity and selectivity. In this study, the application of BIPs in the structure of biosensors, as active area of research in the field of different bacteria detection, was reviewed for detection of <em>Staphylococcus aureus</em> (<em>S. aureus</em>), <em>Salmonella</em>, <em>Vibrio parahaemolyticus</em> (<em>(V. parahaemolyticus</em>) and <em>Escherichia coli</em> (<em>E. coli</em>). In addition, direct strategies and advance methods for bacteria imprinting completely reviewed. The deficiency and future perspective of BIPs sensors were discussed.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111918"},"PeriodicalIF":4.9,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomass-based adsorbents for wastewater remediation: A systematic review on removal of emerging contaminants 用于废水修复的生物质吸附剂:关于去除新兴污染物的系统综述
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-12 DOI: 10.1016/j.microc.2024.111880
Nishita Sharma , Aruna Yadav , Sarita Yadav , Partiksha Panghal , Sonika Singh , Aakash Deep , Surender Kumar
{"title":"Biomass-based adsorbents for wastewater remediation: A systematic review on removal of emerging contaminants","authors":"Nishita Sharma ,&nbsp;Aruna Yadav ,&nbsp;Sarita Yadav ,&nbsp;Partiksha Panghal ,&nbsp;Sonika Singh ,&nbsp;Aakash Deep ,&nbsp;Surender Kumar","doi":"10.1016/j.microc.2024.111880","DOIUrl":"10.1016/j.microc.2024.111880","url":null,"abstract":"<div><div>As anthropogenic activities, industrialization, and technology have grown exponentially in recent decades, the presence of emerging contaminants (ECs) is increasing stress on fresh and sustainable water supplies due to their environmental toxicity. Therefore, a holistic approach is urgently required for the development of efficient technologies to bring the idea of wastewater remediation to fruition. Adsorption with biomass-based adsorbents can contribute to this perception as it offers numerous advantages over existing wastewater treatment technologies. This review ensures a thorough analysis of the potential application of natural sustainable adsorbents based on biomass for efficient removal of ECs including pharmaceuticals and personal care products (PPCPs), agrochemicals, aromatics, and microplastics (MPs). Various factors impacting the adsorption efficiency such as adsorbent dosage, concentration, contact time, pH, and temperature, along with the best-fitted models have been provided for the critical literature analysis. The adsorption mechanism involved was reviewed based on the point of zero charges of adsorbents, the ionic form of adsorbate, the hydrophobicity of adsorbate and adsorbent, surface functional groups, etc. Further, literature gaps were also identified and discussed for directing future research needed in the development of inexpensive, eco-friendly, efficient, reusable adsorbents with the overall process based on circular bio-economy and 4R (Reduce, Recycle, Re-use and Recover) approach, so that it can be commercialized to promote more sustainable futures.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111880"},"PeriodicalIF":4.9,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanoplastics as emerging contaminants: A systematic review of analytical processes, removal strategies from water environments, challenges and perspective 作为新兴污染物的纳米塑料:系统回顾分析过程、从水环境中去除污染物的策略、挑战和前景
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-11 DOI: 10.1016/j.microc.2024.111884
Asiyeh Moteallemi , Mohammad Hadi Dehghani , Fatemeh Momeniha , Salah Azizi
{"title":"Nanoplastics as emerging contaminants: A systematic review of analytical processes, removal strategies from water environments, challenges and perspective","authors":"Asiyeh Moteallemi ,&nbsp;Mohammad Hadi Dehghani ,&nbsp;Fatemeh Momeniha ,&nbsp;Salah Azizi","doi":"10.1016/j.microc.2024.111884","DOIUrl":"10.1016/j.microc.2024.111884","url":null,"abstract":"<div><div>Nanoplastics (NPs) with a size of less than 1 µm have received worldwide attention as an emerging environmental pollutant. Because they are easier for organisms to absorb, they pose higher ecological and health risks than microplastics. Natural water is a significant source of nanoplastics in the environment, and it is important for both human and ecosystem health. The analysis of nanoplastics in waters is still lacking reliable and harmonized methods. Most of the studies successfully identified and removed standard reference nanoplastics from environmental samples, but they were unable to quantify nanoplastics from real field samples. Here, we reviewed studies that measured and removed nanoplastics in environmental waters, such as seawater, rivers, drinking water, wastewater, snow, and so on. Pyrolysis gas chromatography–mass spectrometry (py-GC–MS) and surface-enhanced Raman spectroscopy were two common methods for analyzing nanoplastics in real samples. Mass spectrometry methods are time-consuming and cannot analyze the full nanorange due to particle size restrictions. This approach for measuring nanoplastic mass concentration may involve mistakes and require larger sample quantities. Various strategies for removing nanoplastics, including centrifugation, coagulation, filtration, flocculation, and adsorption, were reviewed. The effectiveness of nanoplastic removal is influenced by parameters such as source, size, type, and purification process. The removal efficiency for nanoplastics is 99 % when combined with filtration and coagulation processes. This study provides basic information for future research on the analysis and removal of nanoplastics from water and wastewater.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111884"},"PeriodicalIF":4.9,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent trends in sampling and sorbent-based sample preparation procedures for bioanalytical applications 生物分析应用中采样和基于吸附剂的样品制备程序的最新趋势
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-11 DOI: 10.1016/j.microc.2024.111903
Marcello Locatelli , Abuzar Kabir , Miryam Perrucci , Halil Ibrahim Ulusoy , Songül Ulusoy , Natalia Manousi , Victoria Samanidou , Imran Ali , Sariye Irem Kaya , Fotouh R. Mansour , Ahmet Cetinkaya , Sibel A. Ozkan
{"title":"Recent trends in sampling and sorbent-based sample preparation procedures for bioanalytical applications","authors":"Marcello Locatelli ,&nbsp;Abuzar Kabir ,&nbsp;Miryam Perrucci ,&nbsp;Halil Ibrahim Ulusoy ,&nbsp;Songül Ulusoy ,&nbsp;Natalia Manousi ,&nbsp;Victoria Samanidou ,&nbsp;Imran Ali ,&nbsp;Sariye Irem Kaya ,&nbsp;Fotouh R. Mansour ,&nbsp;Ahmet Cetinkaya ,&nbsp;Sibel A. Ozkan","doi":"10.1016/j.microc.2024.111903","DOIUrl":"10.1016/j.microc.2024.111903","url":null,"abstract":"<div><div>In the last century, in the analytical field, the interest of researchers in the preliminary phases of the analysis has grown more and more, giving space to important innovations in the field of sample preparation, but above all leading to a renewed interest in this field. It is known that these phases are the most critical of the entire analytical process not only in terms of time, but also in terms of final measurement error. In this perspective, in recent years a growing interest of the Scientific Community and important efforts have been directed towards not only the development of innovative techniques that allow a reduction in sample manipulation while maintaining high analytical performance, but at the same time also towards a reduction in the environmental impact that such procedures can have. In this direction, there is also the possibility of intervening to reduce the quantity of sample processed and, consequently, obtain a reduction in the volumes of solvents and non-green reagents.</div><div>The main objective of this review is to provide an overview of the literature focused on the most modern sorbent-based sampling and sample preparation techniques that are applied (or have been recently developed) in the three main “sections” of instrumental analysis (sensor-based analysis, electrochemical analysis and chromatography-based analysis). In particular, the Authors wanted to outline the main advantages and disadvantages of the different procedures and above all evaluate how the different methods are applied in the field of biological matrix analysis (biological fluids, tissues, etc.). A final paragraph also considers an evaluation and estimate (using the most recent tools) for the environmental impact assessment and how they can be applied in this field (AGREE, AGREEprep, and MoGAPI). Through these applications it is also evaluated how continuous improvement is possible by checking the “critical” points and remedying/optimizing the procedures in this sense.</div><div>The present review finally concludes with a section on future perspectives in which the Authors (based on their vast experience in their respective fields of application) have tried to hypothesize a possible future and a possible way to be considered to ensure that this part of the analytical process can further progress and support the new challenges that daily arise in the field of bioanalytical applications.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111903"},"PeriodicalIF":4.9,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Harnessing the potential of sniffing dogs and GC–MS in analyzing human urine: A comprehensive review of sample preparation and extraction techniques 利用嗅探犬和气相色谱-质谱仪分析人体尿液的潜力:全面回顾样品制备和提取技术
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-11 DOI: 10.1016/j.microc.2024.111907
Laetitia Maidodou , Damien Steyer , Marie-Anaïs Monat , Michelle Leemans , Isabelle Fromantin , Eric Marchioni , Igor Clarot
{"title":"Harnessing the potential of sniffing dogs and GC–MS in analyzing human urine: A comprehensive review of sample preparation and extraction techniques","authors":"Laetitia Maidodou ,&nbsp;Damien Steyer ,&nbsp;Marie-Anaïs Monat ,&nbsp;Michelle Leemans ,&nbsp;Isabelle Fromantin ,&nbsp;Eric Marchioni ,&nbsp;Igor Clarot","doi":"10.1016/j.microc.2024.111907","DOIUrl":"10.1016/j.microc.2024.111907","url":null,"abstract":"<div><div>Pathologies such as cancers or infectious diseases can induce modifications in the concentrations of urinary volatile metabolites. Indeed, urine is a large source of Volatile Organic Compounds (VOCs) from the human body. Canine olfaction and Gas Chromatography coupled to Mass Spectrometry (GC–MS) systems are promising tools for the development of non-invasive diagnosis methods based on the analysis of urine. This review paper aims to provide an overview of materials and methods found in the literature for urinary VOCs analysis by detection dogs and GC–MS instruments. It highlights the impact of urine collection procedures and storage conditions. Then, sample preparation protocols for canine olfaction are discussed, as well as for GC–MS analysis, focusing on headspace-based extraction techniques. In the case of instrumental analysis, a significant variability of volatile profiles can be observed depending on the sample preparation (urine pH, extraction methods), and analytical parameters. Lastly, limitations of urinary VOCs analysis for medical diagnosis purposes are considered.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111907"},"PeriodicalIF":4.9,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances and principles of metal–organic framework for the detection of chloramphenicol: Perspectives and challenges 用于检测氯霉素的金属有机框架的最新进展和原理:前景与挑战
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-10 DOI: 10.1016/j.microc.2024.111878
Miao Liu , Kayhaneh Berijani , Jiaxin Ma , Sirui Guo , Yanqiong Peng , Ying Pan , Ali Morsali , Yong Huang
{"title":"Recent advances and principles of metal–organic framework for the detection of chloramphenicol: Perspectives and challenges","authors":"Miao Liu ,&nbsp;Kayhaneh Berijani ,&nbsp;Jiaxin Ma ,&nbsp;Sirui Guo ,&nbsp;Yanqiong Peng ,&nbsp;Ying Pan ,&nbsp;Ali Morsali ,&nbsp;Yong Huang","doi":"10.1016/j.microc.2024.111878","DOIUrl":"10.1016/j.microc.2024.111878","url":null,"abstract":"<div><div>According to the continuous development of today’s society, the production of environmental pollutants has been a severe concern observed in the drug industries. For instance, the demand for the consumption of antibiotics is one of them that is increasing, and the residual hazards of the broad-spectrum antibiotic chloramphenicol (CAP) are widespread, which can not only pollute the environment but can also have negative health impacts on humans. Thus, the detection of CAP is of great significance. Among the used chemical materials to solve this issue, the essential metal–organic skeletons, namely metal–organic frameworks (MOFs) have promising applications due to their advantages such as large specific surface area (SA), abundant pores, and luminescent properties. This paper describes the principles of electrochemical, fluorescent, and probe assays related to the detection of CAP. A more comprehensive overview of the use of MOFs for the detection of CAP and other antibiotics in water and food and how CAP can be monitored with high sensitivity, high selectivity, and stability in the form of various sensors is given, as well as future perspectives on MOFs materials that have the potential to be used as sensors.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111878"},"PeriodicalIF":4.9,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toward advanced analytical procedures for detecting Fumonisins in contaminated food and feed using molecularly imprinted polymers: A mini review 利用分子印迹聚合物开发检测受污染食品和饲料中伏马菌素的先进分析程序:微型综述
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-10 DOI: 10.1016/j.microc.2024.111858
M.A. Diab , Heba A. El-Sabban , Kwang-Hyun Baek
{"title":"Toward advanced analytical procedures for detecting Fumonisins in contaminated food and feed using molecularly imprinted polymers: A mini review","authors":"M.A. Diab ,&nbsp;Heba A. El-Sabban ,&nbsp;Kwang-Hyun Baek","doi":"10.1016/j.microc.2024.111858","DOIUrl":"10.1016/j.microc.2024.111858","url":null,"abstract":"<div><div>Fumonisins (FMS), a class of Mycotoxins mostly produced by fusarium species, are found in polluted food and feed and can seriously harm humans and animals. To ensure food safety and regulatory compliance, accurate and dependable analytical techniques are utilized in detecting and measuring these pollutants. This mini-review focused on sophisticated clean-up techniques for Fumonisin (FM) analysis utilizing molecularly imprinted polymer solid phase extraction (MIPSPE). The majority of the molecularly imprinted polymers (MIPs) categories that are intended to extract FMs from the food matrix were discussed, along with a list of well-known chromatographic techniques and MIP-based electrochemical sensors to detect FMs<strong>.</strong></div><div>By imitating FM-specific natural sites, MIPSPE provides great selectivity, sensitivity, and reproducibility while improving the accuracy of subsequent analytical tests. This review includes the synthesis of MIPs, extraction protocol optimization, and integration with several detection techniques like High-Performance Liquid Chromatography <strong>(</strong>HPLC) and Liquid Chromatography-Mass Spectroscopy (LC-MS). It also covers recent advancements in MIPSPE technology.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111858"},"PeriodicalIF":4.9,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of electrochemical biosensors in monitoring Apolipoprotein B-100 as a diagnostic tool for cardiovascular disease 电化学生物传感器在监测载脂蛋白 B-100 作为心血管疾病诊断工具中的作用
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-09 DOI: 10.1016/j.microc.2024.111867
Sara Ranjbari , Wael Almahmeed , Prashant Kesharwani , Amirhossein Sahebkar
{"title":"The role of electrochemical biosensors in monitoring Apolipoprotein B-100 as a diagnostic tool for cardiovascular disease","authors":"Sara Ranjbari ,&nbsp;Wael Almahmeed ,&nbsp;Prashant Kesharwani ,&nbsp;Amirhossein Sahebkar","doi":"10.1016/j.microc.2024.111867","DOIUrl":"10.1016/j.microc.2024.111867","url":null,"abstract":"<div><div>Cardiovascular disease (CVD) is the leading cause of global mortality. Early identification of CVD and subsequent intervention can significantly improve treatment outcomes. A successful approach to promptly diagnose CVD involves identifying biomarkers present in bodily fluids. Apolipoprotein B-100 (apoB-100) is a critical biomarker associated with CVD and plays a significant role in its progression. Elevated levels of apoB-100 (&gt;100 mg/dL) are linked to a higher risk of CVD, underscoring its importance for accurate diagnosis and effective treatment strategies. Electrochemical biosensors offer advantages in monitoring apoB-100 due to their speed, portability, and on-site analysis capabilities. This review provides a comprehensive analysis of how apoB-100 levels change in biological fluids as CVD advances. It includes a detailed explanation of the construction and analytical capabilities of various electrochemical sensors. A comparison of electrochemical biosensors using amperometric, potentiometric, voltammetric, conductometric, and impedimetric methods is presented. Additionally, the suitability of these sensors for measuring apoB-100 in clinical samples, including serum, plasma, whole blood, and other bodily fluids, is evaluated. Furthermore, the challenges associated with electrochemical sensors as diagnostic tools for apoB-100 in CVD biomarker detection are examined, and potential future directions and trends are outlined.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111867"},"PeriodicalIF":4.9,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Next-generation smart biomaterials for storage and extraction of bioanalytical samples: Current standing and path forward 用于储存和提取生物分析样本的新一代智能生物材料:现状与未来之路
IF 4.9 2区 化学
Microchemical Journal Pub Date : 2024-10-05 DOI: 10.1016/j.microc.2024.111846
Sohan G. Jawarkar, Megha Pillai, Prasad Chavan, Pinaki Sengupta
{"title":"Next-generation smart biomaterials for storage and extraction of bioanalytical samples: Current standing and path forward","authors":"Sohan G. Jawarkar,&nbsp;Megha Pillai,&nbsp;Prasad Chavan,&nbsp;Pinaki Sengupta","doi":"10.1016/j.microc.2024.111846","DOIUrl":"10.1016/j.microc.2024.111846","url":null,"abstract":"<div><div>Smart biomaterials are gaining increasing importance in the field of bioanalytical sciences because of the unique ability to change their inherent properties as per need. Recently, many advancements have been witnessed in the storage techniques of biological samples in solid state. Among these, dried blood spot and dried plasma spot methods have unique advantages as cutting-edge approaches. However, such methods are capable to accommodate only a very low volume of sample. To overcome this limitation, the application of smart biomaterial for the storage and extraction of biological samples is now being widely explored. The primary focus of this review is to assess the potential of smart biomaterial for the storage and extraction of bioanalytical samples. The applicability of biomaterials as sorbents for bioanalytical sample extraction and storage emphasizing their unique nature, characterization techniques, and constraints are critically evaluated in this review. Furthermore, applications of biomaterials in tissue engineering, drug delivery, and 3D-printing showcasing their potential to address key challenges in healthcare have been discussed. This review provides a clear-insights into the future directions of smart biomaterial as a sorbent for bioanalytical sample preparation and storage. Interdisciplinary collaboration and translational efforts are identified as a need of the hour to harness the full potential of smart biomaterials in clinical applications.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111846"},"PeriodicalIF":4.9,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信