Microchemical Journal最新文献

{"title":"Detecting tetracycline with one drop of water in a zeolitic sensor through visualized cyan light","authors":"Xingai Ge ,&nbsp;Yanqiu Chen ,&nbsp;Na Zhang ,&nbsp;Xiyuan Tong ,&nbsp;Yifeng E ,&nbsp;Li Li ,&nbsp;Kun Qian ,&nbsp;Zhuozhe Li","doi":"10.1016/j.microc.2025.115211","DOIUrl":"10.1016/j.microc.2025.115211","url":null,"abstract":"<div><div>The excessive utilization of antibiotics has led to a considerable amount of tetracycline (TC) residues in the water system, giving rise to ecosystem disruption and human health risk. Detecting TC residues through a pragmatic, rapid, and sensitive approach is an imperative need. In this research, a composite fluorescence sensor is combined with the Ti<img>Fe dual-doped nanoparticles and the sodalite (SOD) structured zeolite. The sensor is as-synthesized in a one-pot reaction under the hydrothermal condition, in which the Ti and Fe nanoparticles are uniformly embedded and highly dispersed within the zeolite. With the LOD 0.12 μM of TC, cyan light can be observed through the sensor. A self-service home testing solution is prepared by mixing a drop of liquid to be tested, milligrams of sensor powders, and several milliliters of ethanol. Under ultraviolet light irradiation, the cyan emission light indicates the presence of TC in the liquid. And the light became stronger with more TC concentration. The sensor demonstrates outstanding stability, repeatability, selectivity, and sensitivity.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115211"},"PeriodicalIF":4.9,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micro-hotplate gas sensor based on tungsten trioxide (WO3) nanoflakes for detecting chemical warfare agent simulants","authors":"Şule Özdilek ,&nbsp;Ahmet Ünverdi ,&nbsp;Ümit Doğan ,&nbsp;Alican Ökçün ,&nbsp;Serkan Büyükköse ,&nbsp;Zafer Ziya Öztürk","doi":"10.1016/j.microc.2025.115196","DOIUrl":"10.1016/j.microc.2025.115196","url":null,"abstract":"<div><div>In this study, micro-hotplate chemiresistive gas sensors based on pristine, and silver (Ag) loaded tungsten trioxide (WO₃) nanoflakes are developed and comparatively evaluated for detecting chemical warfare agent (CWA) simulants. WO₃ nanoflakes are synthesized directly on a platinum (Pt) micro-hotplate platform via hydrothermal method. X-Ray diffraction (XRD) results show the orthorhombic phase of WO₃. Scanning electron microscopy (SEM) analysis proves the dense nanoflake morphology of WO₃, while Energy dispersive spectroscopy (EDS) analysis proves the formation of WO₃ with atomic ratio of W/O ∼ 25 % / 75 %. WO₃ samples are functionalized with a nominal thickness of 10 nm Ag layer (∼2.5 % wt.) using RF magnetron sputtering. The fabricated sensors are tested against CWA simulants, including hydrogen cyanide (HCN), hydrogen sulfide (H₂S), 2-chloroethyl ethyl sulfide (2-CEES), dimethyl methylphosphonate (DMMP), dipropylene glycol monomethyl ether (DPGME), and trimethyl phosphate (TMP). Ag loading enhances sensitivity and selectivity toward HCN, achieving a response of 27.70 at 1 ppm compared to 6.93 for pristine WO₃, while the response time is observed as 112 s. The improved performance is attributed to specific interaction between HCN molecules and Ag sites on the WO₃ surface, providing a distinct response mechanism. Compared to previous studies that have reported broad or non-specific responses toward toxic gases, this work demonstrates for the first time a sharp enhancement in HCN selectivity through Ag nanoparticle decoration, making it highly suitable as a targeted CWA detection. These results highlight the impact of Ag loading on gas selectivity, offering a strategic approach for designing WO₃ based sensors tailored for specific gas detection applications and emphasizing its potential for real-time CWA detection.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115196"},"PeriodicalIF":4.9,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tetrahedral DNA cluster-based signal-amplified Impedimetric biosensor for ultrasensitive detection of Ochratoxin A","authors":"Zhixue Yu ,&nbsp;Yue He ,&nbsp;Hui Wang ,&nbsp;Dongxia Pan ,&nbsp;Ruipeng Chen ,&nbsp;Xiangfang Tang ,&nbsp;Junhu Yao ,&nbsp;Benhai Xiong","doi":"10.1016/j.microc.2025.115204","DOIUrl":"10.1016/j.microc.2025.115204","url":null,"abstract":"<div><div>Ochratoxin A (OTA) is a highly toxic mycotoxin with nepHrotoxicity, hepatotoxicity, and carcinogenicity. It poses a long-term threat to the health of humans and animals. Although screen printed electrodes (SPE) with aptamer functionalization provide promising detection capabilities, their applications are limited by inherent weak electrochemical signals, prompting the need for signal amplification strategies. In this study, tetrahedral DNA clusters (TDCs) were prepared as aptamer probes for OTA, and an aptamer-based electrochemical sensing method for OTA was established for signal amplification. Multiple single-stranded DNA (ssDNA) were designed to self-assemble into tetrahedral DNA nanostructure (TDN) through base complementarity, with the OTA aptamer attached to one vertex. Additional ssDNA strands were further utilized to extend TDNs at the three remaining vertices, forming a DNA tetrahedral cluster. The method had a linear range of 1 pg/mL to 100 ng/mL (LOD = 1 pg/mL) for detecting OTA, with excellent specificity and satisfactory recovery rate in feed samples</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115204"},"PeriodicalIF":4.9,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sulfonate-modified cyanine probe enables real-time monitoring of oxidative stress in colitis via hydroxyl radical-specific fluorescence turn-on","authors":"Lan Gu ,&nbsp;Juan Song ,&nbsp;Tong Wang ,&nbsp;You-Zhen Feng ,&nbsp;Kai Wang ,&nbsp;Qiong Lin","doi":"10.1016/j.microc.2025.115212","DOIUrl":"10.1016/j.microc.2025.115212","url":null,"abstract":"<div><div>Hydroxyl radicals (·OH) are pivotal in inflammatory diseases but difficult to detect in vivo. We developed a near-infrared probe (<strong><em>Re</em>-Cy7-SO</strong>_{<strong>3</strong>}<strong>H</strong>) based a sulfonated cyanine dye, which shows ·OH-specific fluorescence activation at 800 nm through oxidative C<img>N bond cleavage and structural planarization. Density functional theory calculations confirmed enhanced intramolecular charge transfer upon planarization. The probe demonstrated excellent water solubility (logP = −4.333), selectivity (R² = 0.987), and biosafety (&gt;90 % viability at 25 μM), enabling real-time ·OH monitoring in lipopolysaccharide (LPS) stimulated macrophages and dextran sulfate sodium (DSS) induced colitis mice. In vivo imaging revealed disease severity-dependent fluorescence, with 2.5 % DSS-treated mice showing 3.2-fold higher colonic signals than controls at 90 min.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115212"},"PeriodicalIF":4.9,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel electrochemical sensor based on hollow and porous N-doped carbon frameworks embedded with Co nanoparticles for the determination of 4-nitrophenol","authors":"Qirong Zhou ,&nbsp;Yanting Zhou ,&nbsp;Jiaqi Wu ,&nbsp;Junjie Fei ,&nbsp;Feng Wu ,&nbsp;Yixi Xie ,&nbsp;Li Zhang","doi":"10.1016/j.microc.2025.115218","DOIUrl":"10.1016/j.microc.2025.115218","url":null,"abstract":"<div><div>4-Nitrophenol (4-NP), a priority pollutant with significant adverse effects on human health and the environment, necessitates the development of sensitive and reliable detection methods. Herein, we report a novel electrochemical sensor for 4-NP detection based on a ZIF-8-derived hollow and porous N-doped carbon framework embedded with uniformly dispersed cobalt nanoparticles (Co-HMCF). This material ingeniously integrates hierarchical structures, N-doping, and Co NPs loading, endowing it with excellent conductivity, a large specific surface area, and superior catalytic activity. These attributes synergistically enhance the electrochemical sensing performance. Under optimal conditions, the achieved wide linear range was 5 μM to 600 μM. The low detection limit of 0.79 μM with high sensitivity of 5.19 μA μM⁻¹ cm⁻² was obtained. Furthermore, the Co-HMCF sensor holds outstanding selectivity and stability. Therefore, the innovative structure and excellent properties of carbon frameworks make them alternative materials for various electrochemical sensors for the detection of other toxic organic pollutants.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115218"},"PeriodicalIF":4.9,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An electrochemical biosensor with engineered Co-N active sites loaded on humic acid for catalyzing and detecting of biomolecules","authors":"Yijie Xuan ,&nbsp;Aili Zhao ,&nbsp;Junjie Wang ,&nbsp;Shuai Wang ,&nbsp;Jingui Wang ,&nbsp;Min Cui","doi":"10.1016/j.microc.2025.115205","DOIUrl":"10.1016/j.microc.2025.115205","url":null,"abstract":"<div><div>Humic acid (HA), a natural organic matter (NOM), exhibits high biocompatibility, low toxicity and antioxidant properties, making it highly suitable as a biosensing interface for capturing, binding, catalyzing and detecting diverse biomolecules. However, the inherently poor conductivity of HA has resulted in very few studies on its electrochemical catalysis and detection of biomolecules. This study focused on the Co-N active sites supported on nitrogen-doping HA (N-HA), primarily investigating their electrochemical catalytic performance towards various biomolecules and biosensing capability for characteristic biomolecules. Both N doping and Co loading on HA increased surface area, enhanced conductivity, promoted electron transfer, and boosted detection sensitivity. The engineered Co-N active sites possessed the capability to selectively catalyze diverse biomolecules including dopamine (DA), ascorbic acid (AA), uric acid (UA) and 5-hydroxytryptamine (5-HT), which improved the anti-interference property. Developed biosensor based on Co@N-HA achieved sensitive detecting of DA and AA with the extremely low catalyzing potentials (0.20 V for DA, 0.25 V for AA), the wide linear ranges, the low limits of detection (LODs, 1.03 μM for AA, 1.21 μM for DA) and limits of quantification (LOQs, 3.40 μM for AA, 4.03 μM for DA), accompanied by high reproducibility and stability. Biosensor enabled reliable target detection in biological fluids, including artificial sweat and kiwifruit juice, with high selectivity and sensitivity, declaring its robustness for practical applications. The work expanded the application of HA in electrochemical biosensing field.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115205"},"PeriodicalIF":4.9,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable extraction of phenolics from underutilised onion and garlic field residues: subcritical water approach and bioactivity evaluation","authors":"Slađana Krivošija ,&nbsp;Mire Zloh ,&nbsp;Nataša Nastić ,&nbsp;Stela Jokić ,&nbsp;Krunoslav Aladić ,&nbsp;Aleksandra Jovanović Galović ,&nbsp;Senka Vidović","doi":"10.1016/j.microc.2025.115199","DOIUrl":"10.1016/j.microc.2025.115199","url":null,"abstract":"<div><div>Increasing production of agri-food waste is a global challenge, considering the huge amounts of waste materials that are generated, and often not used or disposed adequately. During the agricultural production and further use and processing of onion and garlic, a large amount of waste is generated globally. Up to now, scientific research was mainly focused on the waste/by-products generated in the processing phase – by the food industry. However, a significant part of the waste originated from these crops comes from the agricultural production and harvesting phase. This material, agricultural waste from onion (OAW) and garlic (GAW), is recognised as the cut dried upper part - dried stalks, husks and leaves, which remains in the arable fields, and is ploughed or in some cases burned causing harmful effects on the environment. The aim of this study is to investigate the potential of this kind of waste by applying high-efficiency subcritical water extraction (SWE), and focusing on the influence of temperature as a key parameter in the extraction process. The targeted compounds of investigation were polyphenols. The dominant compounds identified and quantified by HPLC-DAD analysis were phenolic acids (especially protocatechuic and neochlorogenic) and flavonoids (quercetin and quercetin 3-β-D-glucoside in the case of OAW, and epigallocatechin, epicatechin and catechin in the case of GAW). Based on the chemical profile, an <em>in silico</em> study was conducted where the effects of the compounds of OAW and GAW extracts were specified with a focus on cardiovascular diseases. Furthermore, the anticancer activity of the selected extracts was evaluated, contributing to sustainable strategies for agricultural waste use.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115199"},"PeriodicalIF":4.9,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145007508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of an electrochemical sensor based on 3-thiophene methanol and 3-methylthiophene supported molecularly imprinted polymer for the sensitive and selective detection of levothyroxine","authors":"Emrah Yayan,&nbsp;Dilek Kazıcı,&nbsp;Ebru Kuyumcu Savan","doi":"10.1016/j.microc.2025.115192","DOIUrl":"10.1016/j.microc.2025.115192","url":null,"abstract":"<div><div>Levothyroxine (L-T4) is the most frequently prescribed drug to treat thyroid hormone deficiency. Herein, a levothyroxine-specific sensor was designed using the molecular imprinting method to increase the selectivity of the target molecule on the electrode surface and prevent interference effects. 3-thiophene methanol (3-TMeOH) and 3-methyl thiophene (3-MT) monomers were electro-polymerized as molecularly imprinted polymer (MIP) on the surface of a glassy carbon electrode (GCE) in the presence of L-T4. Gaps were created on the surface of the designed electrode to fit the target molecule by removing L-T4 molecules. This way, L-T4-specific selective structures were formed on the sensors' surface. The results showed that under optimized conditions, the fabricated modified sensor (3-TMeOH/3-MT@MIP/GCE) exhibited a linear response in the concentration range of 1.0–5.7 μM with limit of determination, limit of quantitation, and sensitivity values <!--> <!-->of 1.83 nM, 5.50 nM, and 0.0023 <span><span>A.L.mmol⁻¹.cm</span><svg><path></path></svg></span>⁻², respectively. The analytical method validation process of the voltammetric determination method using the sensor selective to L-T4 was completed following the method's intended use. The designed modified sensor exhibited high sensitivity, repeatability, excellent stability, selectivity, and high precision and accuracy.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115192"},"PeriodicalIF":4.9,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochar from sewage sludge as a sustainable and green dispersive solid pHase adsorbent in the clean-up of QuEChERS extracts: First application to the LC–MS/MS analysis of contaminants of emerging concern in edible crop samples","authors":"Lapo Renai ,&nbsp;Michelangelo Fichera ,&nbsp;Federico Sinigaglia ,&nbsp;Giulia Bonaccorso ,&nbsp;Lorenzo Bini ,&nbsp;Stefano Biricolti ,&nbsp;Edgardo Giordani ,&nbsp;Donatella Fibbi ,&nbsp;Luca Rivoira ,&nbsp;Maria Concetta Bruzzoniti ,&nbsp;Massimo Del Bubba","doi":"10.1016/j.microc.2025.115198","DOIUrl":"10.1016/j.microc.2025.115198","url":null,"abstract":"<div><div>Biochar from pyrolysis of sewage sludge (SS-BC) was tested for the first time as dispersive solid-phase extraction (d-SPE) sorbent in the clean-up of QuEChERS extracts of rocket, tomato, and strawberry for the analysis of a wide group of contaminants of emerging concern, which included 23 analytes belonging to the classes of pharmaceutical compounds (PhCs), perfluorinated alkyl substances (PFASs), and sunscreen agents (SAs). The SS-BC was compared for its clean-up efficiency with graphitized carbon black (GCB) and styrene-divinylbenzene copolymer (SDVB), evaluating recovery efficiency (R) in matrix-free experiments, matrix effect (ME) reduction and apparent recovery (AR%). SS-BC at 10 mg/mL of extract showed high ME removals for all target analytes, but variable recoveries (R% = 67 ± 36), inversely and strongly correlated with the number of aromatic rings and directly correlated with the size and hydrophobicity of the molecule. BC was effective as d-SPE sorbent for the QuEChERS analysis of PFAS (AR% = 96 %–136 %, depending on the crop analysed), while for the simultaneous analysis of both non-aromatic and aromatic analytes better results were obtained by properly mixing SS-BC with SDVB. The proposed QuEChERS extraction and clean-up approach was compared for its environmental greenness with previously published methods, showing the highest score (0.53 vs. 0.35–0.47). Based on the results obtained, SS-BC represents a sustainable and cost-effective bio-based material that can replace GCB as d-SPE sorbent for the analysis of a wide variety of emerging contaminants, covering a broad range of physicochemical properties (e.g., Log D at pH = 7 in the range − 2–6.8) in various pigmented crop extracts.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115198"},"PeriodicalIF":4.9,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gold-graphene quantum dot-N-doped porous carbon-based electrochemical aptasensor with DNA amplification for ultrasensitive detection of omethoate","authors":"Dan Xu,&nbsp;Mingyuan Liu,&nbsp;Lizhong Wang,&nbsp;Lei Wang,&nbsp;Hui Yang","doi":"10.1016/j.microc.2025.115181","DOIUrl":"10.1016/j.microc.2025.115181","url":null,"abstract":"<div><div>The synthesis of highly catalytically active gold‑carbon composites remains a significant challenge. This study reports a novel approach for synthesizing a gold-histidine functionalized graphene quantum dots-N-doped porous carbon composite (Au-HFGQD-NPC). Gold ions (Au³⁺) were coordinated with HFGQD through Au<img>N bonds to form Au-HFGQD complexes, which were then combined with polyacrylamide, freeze-dried, and thermally reduced under a N₂ atmosphere at 500 °C. The resulting Au-HFGQD-NPC features a three-dimensional porous architecture with uniformly dispersed, small Au nanoparticles within the carbon matrix, which enhances its catalytic performance. This composite was utilized as a sensing material to develop an electrochemical aptasensor for omethoate detection that incorporates a DNA recycling amplification strategy. The aptasensor employed a triple-helix aptamer probe (TAP) consisting of an aptamer loop, two segment stems, and a triplex oligonucleotide (probe). Omethoate binding to the aptamer induces the TAP conformational change, releasing the probe. The released probe hybridizes with hairpin DNA 1 (H1) immobilized on the electrode surface via Au<img>S bonds. Subsequently, ferrocene-modified hairpin DNA 2 (H2-Fc) hybridizes with H1, releasing the probe and triggering the next cycle. This recycling mechanism results in the accumulation of multiple H2-Fc molecules on the electrode. The highly catalytically active Au-HFGQD-NPC then catalyzes the oxidation of Fc, leading to a significantly enhanced detection signal. The differential pulse voltammetry peak current exhibited a linear relationship with the logarithm of omethoate concentration over the range of 3 × 10⁻¹⁵ to 1 × 10⁻⁹ M, achieving a detection limit of 1.2 × 10⁻¹⁵ M. The proposed aptasensor demonstrates high sensitivity, selectivity, and stability, and has been successfully applied for determine omethoate in cabbage samples.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115181"},"PeriodicalIF":4.9,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}